| danazol oral / Generic mfg. |
ChiCTR-TRC-12002424: Clinical study on therapeutic efficacy and mechanism of all-trance-retinoid acid in refractory immune thrombocytopenia patients |
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| Completed | 4 | 80 | | All-trance retinoid acid + Danazol ;Danazol | Peking University People's Hospital, Peking University Institute of Hematology; Level of the institution：, Beijing Municipal Science and technology Commission | immune thrombocytopenia | | | | |
ChiCTR1900025219: A prospective, open-label, multicenter clinical trail for Ruxolitinib combined with Prednisone, Thalidomide and Danazole in adult patients wiht myelofibrosis |
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| Not yet recruiting | 4 | 80 | | Ruxolitinib combined with Prednisone, Thalidomide and Danazol | Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences; Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Institute of Hematology and Blood Diseases Hospital,Chinese Academy of Medical Sciences | myelofibrosis | | | | |
ChiCTR2000041485: Efficacy of Danazol after no response to cyclosporin in transfusion independent aplastic anemia: a prospective study |
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| Recruiting | 4 | 228 | | Cyclosporine combined with danazol ;Cyclosporine | Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, self-raised | transfusion independent aplastic anemia | | | | |
| Completed | 3 | 195 | Europe, Canada, US, RoW | Momelotinib, MMB, GS-0387, CYT387, Placebo to match danazol, Danazol, Danocrine, Placebo to match momelotinib | Sierra Oncology LLC - a GSK company | Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis | 12/21 | 12/22 | | |
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2018-004400-19: Study of the effects of telomerase reactivation with Danazol on ovarian function. A Pilot Study. Estudio de los efectos de la reactivación de la telomerasa con Danazol en la función ovárica. Estudio piloto. |
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| Not yet recruiting | 3 | 45 | Europe | Capsule, DANATROL | IVIRMA MADRID, FINOX AG | low ovarian reserve Baja respuesta ovárica, Premature ovarian aging Envejecimiento del ovario, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
PACIFICA, NCT03165734 / 2017-001772-28: A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis |
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| Recruiting | 3 | 399 | Europe, Canada, US, RoW | Pacritinib, Physician's Choice medications, corticosteroids, hydroxyurea, danazol, low-dose ruxolitinib | CTI BioPharma, PSI CRO | Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis | 06/25 | 12/25 | | |
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NCT05697471: Comparisons of the Therapeutic Effects of Dienogest and Danazol on Endometriosis |
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| Recruiting | 3 | 120 | RoW | Dienogest, Danazol | Far Eastern Memorial Hospital | Endometriosis | 12/25 | 12/25 | | |
NCT04324060: A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia |
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| Active, not recruiting | 2/3 | 75 | RoW | Danazol + rhTPO (recombinant human thrombopoietin injection), Danazol + sodium chloride | Peking Union Medical College Hospital | Low/Intermediate Risk-1 MDS | 03/22 | 12/22 | | |
ACTRN12620001363976p: The TELO-SCOPE Study: Attenuating Telomere Attrition with Danazol. Is there Scope to Dramatically Improve Health Outcomes for Adults and Children with Pulmonary Fibrosis?
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| Not yet recruiting | 2 | 50 | | | The University of Queensland, Australian Government Department of Health, Medical Research Future Fund | Pulmonary fibrosis associated with age adjusted telomere length less than the 10th centile. | | | | |
ACTRN12620001363976: The TELO-SCOPE Study: Attenuating Telomere Attrition with Danazol. Is there Scope to Dramatically Improve Health Outcomes for Adults and Children with Pulmonary Fibrosis?
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| Recruiting | 2 | 50 | | | The University of Queensland, Australian Government Department of Health, Medical Research Future Fund | Pulmonary fibrosis associated with age adjusted telomere length less than the 10th centile. | | | | |
NCT04481282: The Combination of Terbutaline and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 40 | RoW | Terbutaline, Bricanyl Brethine, Danazol, Danocrine, Cleregil, Danol | Peking University People's Hospital | Immune Thrombocytopenia | 03/21 | 07/21 | | |
NCT05353673: The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 120 | RoW | Sitagliptin, JANUVIA, Danazol, Danocrine | Peking University People's Hospital | Immune Thrombocytopenia, Blood Coagulation Disorders, Thrombocytopenia, Physiological Effects of Drugs | 12/22 | 02/23 | | |
NCT05471050: The Combination of Tacrolimus and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 120 | RoW | TAC, Danazol | Peking University People's Hospital | Immune Thrombocytopenia | 03/23 | 06/23 | | |
NCT05281068: The Combination of Iguratimod and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 120 | RoW | Iguratimod, Iremod, Danazol | Peking University People's Hospital, Beijing Hospital, China-Japan Friendship Hospital, Beijing Friendship Hospital, The First Affiliated Hospital of Zhengzhou University, First Affiliated Hospital of Chongqing Medical University, Shanxi Bethune hospital, Shanxi, China | ITP, Immune Thrombocytopenia | 09/23 | 12/23 | | |
NCT05494307: The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia |
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| Not yet recruiting | 2 | 228 | NA | Terbutaline, Danazol | Peking University People's Hospital | Immune Thrombocytopenia | 09/23 | 02/24 | | |
NCT06176911: The Combination of Teriflunomide and Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 124 | RoW | Teriflunomide, AUBAGIO, Danazol | Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital | Immune Thrombocytopenia | 12/24 | 07/25 | | |
NCT05852847: Low-dose Baricitinib Plus Danazol for Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Recruiting | 2 | 216 | RoW | Baricitinib 2 MG [Olumiant], Olumiant, Danazol | Peking University People's Hospital, Beijing Luhe Hospital, Chinese PLA General Hospital, Navy General Hospital, Beijing, Beijing Hospital, Beijing Friendship Hospital, Peking University First Hospital, Peking University Third Hospital, China-Japan Friendship Hospital, Beijing Tsinghua Changgeng Hospital | Immune Thrombocytopenia | 11/24 | 05/25 | | |
TELO-SCOPE, NCT04638517: The Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis |
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| Recruiting | 2 | 50 | RoW | Danazol, Placebo | The University of Queensland | Pulmonary Fibrosis, Telomere Shortening, Telomere Disease, Dyskeratosis Congenita | 12/24 | 06/25 | | |
| Recruiting | 2 | 120 | Europe | Sodium Valproate, Bezafibrate, Medroxyprogesterone, Danazol | Prof. Janet Dunn, Blood Cancer UK, Dudley Group NHS Foundation Trust, University of Birmingham, University of Manchester, King's College Hospital NHS Trust | Myelodysplastic Syndromes (MDS) | 01/25 | 06/25 | | |
NCT04873102: Danazol for Treatment of Cytopenias in Patients With Cirrhosis |
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| Recruiting | 2 | 10 | US | Danazol Pill, Danocrine | University of Southern California | Cirrhosis, Liver, Cytopenia | 11/25 | 11/25 | | |
NCT03312400: Low-Dose Danazol for the Treatment of Telomere Related Diseases |
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| Recruiting | 2 | 40 | US | Danazol | National Heart, Lung, and Blood Institute (NHLBI) | Telomere Disease | 04/26 | 10/27 | | |
NCT03460808: The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia |
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| Not yet recruiting | 1/2 | 200 | RoW | atorvastatin, Acetylcysteine, Danazol, Danocrine, Cleregil, Danol | Peking University People's Hospital | Immune Thrombocytopenia | 01/20 | 01/23 | | |
| Not yet recruiting | 1/2 | 40 | NA | Danazol 200 MG | Assistance Publique - Hôpitaux de Paris | Telomere Shortening, Telomere Length, Mean Leukocyte | 10/21 | 10/22 | | |
| Withdrawn | 1/2 | 30 | NA | Danazol Pill, Placebo | Brigham and Women's Hospital | Short Telomere Length, Lung Transplant | 11/21 | 01/22 | | |
ChiCTR1800020309: Autophagy mechanism of ovarian EMs cells with intervention of Luo's prescription for endometriosis based on PI3K/Akt/mTOR signaling pathway: an in vitro study |
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| Not yet recruiting | N/A | 200 | | None ;Luo 's prescription for endometriosis ;Luo 's prescription for endometriosis ;Luo 's prescription for endometriosis ;Danazol ;Danazol ;Danazol ;Temsirolimus ;Temsirolimus ;Temsirolimus | The First Affiliated Hospital of Guangzhou University of Chinese Medicine; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Traditional Chinese Medicine Bureau Of Guangdong Province | Endometriosis | | | | |
ChiCTR1900027553: Clinical therapies for patients in subtypes of non-severe aplastic anemia |
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| Not yet recruiting | N/A | 490 | | Cyclosporine ;Cyclosporine ;Cyclosporine+Danazol ;CSA+TPO+G-CSF | Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, Tianjin Major Disease Prevention and Control Science and Technology Project | non-severe aplastic anemia | | | | |
ChiCTR1800016177: Withdraw by the investigator Efficacy and safety of danazol combined with low-dose glucocorticoids in the treatment of refractory/recurrent primary immune thrombocytopenia: a multicenter, single arm, prospective and open clinical study |
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| Suspended | N/A | 30 | | danazol combined with low-dose glucocorticoids | Second Affiliated Hospital of Dalian Medical University; Second affiliated hospital of Dalian medical university, Research funding | Immune thrombocytopenic purpura | | | | |