phenytoin / Generic mfg.  >>  Phase 3
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11 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
phenytoin / Generic mfg.
NCT00004817: Phase III Double Blind Trial of Valproate Sodium for Prophylaxis of Post Traumatic Seizures

Completed
3
385
US
phenytoin, valproate sodium
National Institute of Neurological Disorders and Stroke (NINDS), Harborview Injury Prevention and Research Center
Post-Traumatic Seizure Disorder, Head Injuries
 
 
NCT00210782: A Comparison of the Effectiveness and Safety of Topiramate and Phenytoin in Patients With New Onset Epilepsy Requiring Rapid Initiation of Antiepileptic Drug Treatment

Completed
3
262
US
topiramate, phenytoin
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Ortho-McNeil Neurologics, Inc.
Epilepsy
 
08/07
PIGO, NCT00781196: Folic Acid Supplementation in Phenytoin Induced Gingival Overgrowth

Completed
3
120
RoW
folic acid, placebo
All India Institute of Medical Sciences, New Delhi
Gingival Overgrowth
01/09
07/09
NCT00591006: Phenytoin as a Neuroprotective Agent Against Corticosteroid-induced Functional Imaging Changes

Completed
3
17
US
Phenytoin (brand name Dilantin), 5,5-Diphenylhydantoin, Fenitoin, Antisacer, Difenin, Dihydan, Dilantin, Diphenylhydantoin, Epamin, Hydantol, Sodium Diphenylhydantoinate, Hydrocortisone, Cortef, Corticosteroids, Placebo, Sugar pill
University of Texas Southwestern Medical Center
Healthy
07/09
07/09
NCT01586208 / 2009-013796-22: Refractory Status Epilepticus Treatment Study

Completed
3
5
Europe
valproic acid (VPA), Valrpoic acid, Phenytoin, Benzodiazepines, Status Epilepticus Refractarius
Hospital Universitari de Bellvitge, Hospital Vall d'Hebron, Germans Trias i Pujol Hospital, Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta, Hospital Clinic of Barcelona
Grand Mal Status Epilepticus, Non-convulsive Status Epilepticus
05/12
10/12
2015-001222-42: A comparison of the effectiveness and safety of topiramate and phenytoin in patients with new onset epilepsy requiring rapid initiation of antiepileptic drug treatment

 
3
261
US
TOPAMAX, PHENYTEK, Tablet, Capsule, TOPAMAX, PHENYTEK
Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Johnson & Johnson Pharmaceutical Research and Development
New onset epilepsy, Seizures unprovoked, Diseases [C] - Nervous System Diseases [C10]
 
 
NCT02374567: Pharmacovigilance in Gerontopsychiatric Patients

Terminated
3
407
Europe
Phenobarbital, Phenytoin, Carbamazepine, Oxcarbazepine, Valproic Acid, Lamotrigine, Topiramate, Gabapentin, Levetiracetam, Pregabalin, Lacosamide, Clonazepam, Biperiden, Levomepromazine, Fluphenazine, Perphenazine, Perazine, Thioridazine, Haloperidol, Melperone, Pipamperone, Bromperidol, Benperidol, Sertindole, Ziprasidone, Flupentixol, Chlorprothixene, Zuclopenthixol, Fluspirilene, Pimozide, Clozapine, Olanzapine, Quetiapine, Sulpiride, Tiapride, Amisulpride, Prothipendyl, Risperidone, Aripiprazole, Paliperidone, Diazepam, Oxazepam, Lorazepam, Bromazepam, Clobazam, Alprazolam, Hydroxyzine, Buspirone, Chloral Hydrate, Flurazepam, Nitrazepam, Triazolam, Lormetazepam, Temazepam, Midazolam, Brotizolam, Zopiclone, Zolpidem, Zaleplon, Melatonin, Clomethiazole, Diphenhydramine, Promethazine, Imipramine, Clomipramine, Opipramol, Trimipramine, Amitriptyline, Nortriptyline, Doxepin, Maprotiline, Amitriptyline oxide, Fluoxetine, Citalopram, Paroxetine, Sertraline, Fluvoxamine, Escitalopram, Tranylcypromine, Moclobemide, Mianserin, Trazodone, Mirtazapine, Bupropion, Venlafaxine, Reboxetine, Duloxetine, Agomelatine, Pyritinol, Piracetam, Donepezil, Rivastigmine, Galantamine, Memantine, Nicergoline, Acamprosate, Lithium
Hannover Medical School
Dementia, Depression, Schizophrenia, Psychosomatic Disorders, Anxiety Disorders
06/17
06/17
NCT03650270: Childhood Convulsive Status Epilepticus Management In A Resource Limited Setting

Completed
3
198
RoW
Phenobarbital, Phenytoin, Midazolam
University of Cape Town
Pediatric Status Epilepticus
03/18
03/18
MAST, NCT04573803: Pharmacological Management of Seizures Post Traumatic Brain Injury

Not yet recruiting
3
1649
NA
Phenytoin Sodium, Levetiracetam, Keppra
Cambridge University Hospitals NHS Foundation Trust, University of Cambridge
Traumatic Brain Injury, Post Traumatic Seizures
03/26
03/28
Tyme-88-Panc , NCT03512756: A Randomized Phase 2/3 Multi-Center Study of SM-88 in Patients With Metastatic Pancreatic Cancer

Completed
2/3
132
US
SM-88 used with MPS (methoxsalen, phenytoin, sirolimus), SM-88, Racemetyrosine, Capecitabine, Gemcitabine, and 5-FU, Physician's Choice
Tyme, Inc
Pancreatic Cancer
04/22
04/22
EPHENE, NCT04647877: Phenytoin Cream for the Treatment of Neuropathic Pain

Completed
2/3
81
Europe
phenytoin cream, Placebo cream
David J. Kopsky, Princess Beatrix Muscle Foundation, Dr. C.J. Vaillant Fonds
Chronic Idiopathic Axonal Polyneuropathy
06/23
06/23

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