| phenytoin / Generic mfg. |
ACTRN12619000730101: Antiarrhythmic effects of phenytoin or dantrolene in patients with cardiomyopathy. |
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| Not yet recruiting | 1 | 105 | | | University of Newcastle, John Hunter Hospital | Heart failure with reduced ejection fraction (HFrEF), Arrhythmia, Cardiomyopathy | | | | |
| Not yet recruiting | 1 | 105 | | | University of Newcastle, John Hunter Hospital | Heart failure with reduced ejection fraction (HFrEF); Arrhythmia; Cardiomyopathy | | | | |
NCT00011063: Effect of Ginkgo Biloba on Phenytoin Elimination |
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| Completed | 1 | 12 | US | Ginkgo Biloba | National Institutes of Health Clinical Center (CC) | Healthy | | 04/01 | | |
NCT00000285: Effects of Phenytoin on Cocaine Use in Humans - 2 |
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| Completed | 1 | 0 | US | Phenytoin | National Institute on Drug Abuse (NIDA), University of Minnesota | Cocaine-Related Disorders | | 12/01 | | |
NCT01878578: The Effect of BIA 2-093 on the Steady-state Pharmacokinetic Profile of Phenytoin in Patients |
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| Terminated | 1 | 4 | Europe | Eslicarbazepine acetate, BIA 2-093, phenytoin, Hidantina® 100 mg tablets, Placebo, Placebo tablets | Bial - Portela C S.A. | Epilepsy | 03/03 | 03/03 | | |
NCT00647621: Steady-State Study of Extended Phenytoin Sodium Capsules 100 mg and Dilantin® Kapseals® 100 mg |
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| Completed | 1 | 72 | US | Extended Phenytoin Sodium Capsules 100 mg, Dilantin® Kapseals® 100 mg | Mylan Pharmaceuticals Inc | Healthy | 12/05 | 12/05 | | |
NCT00426673: An Open-Label Interaction Study to Look at the Effects of Brivaracetam on Phenytoin When Taken Together in 15 Adult Patients With Epilepsy. |
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| Completed | 1 | 15 | US | Brivaracetam (ucb34714) | UCB Pharma | Epilepsy | 06/06 | 06/06 | | |
NCT02283827: Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Phenytoin. |
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| Completed | 1 | 32 | Canada | BIA 2-093, Eslicarbazepine acetate, ESL, Phenytoin, PHT | Bial - Portela C S.A. | Epilepsy | 03/07 | 03/07 | | |
| Completed | 1 | 119 | US | lamotrigine, atorvastatin, phenytoin | GlaxoSmithKline | Epilepsy | 09/08 | 09/08 | | |
| Terminated | 1 | 6 | NA | topiramate, Topamax, phenytoin, Dilantin | University of Pennsylvania | Traumatic Brain Injury, Epilepsy | 02/09 | 02/09 | | |
NCT01122953: Bioequivalence Study Of PHENYTOIN Suspension Made By Pfizer, Versus EPAMIN® Made By McNeil LA LLC In Healthy Volunteers Under Fasting Conditions |
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| Completed | 1 | 34 | RoW | Phenytoin, Epamin | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Healthy | 06/10 | 06/10 | | |
NCT01122940: Bioequivalence Study Of Phenytoin Suspension Versus Epamin® In 34 Healthy Volunteers. |
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| Completed | 1 | 32 | RoW | Epamin: Reference Drug, Phenytoin: Study Drug | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Healthy | 08/10 | 08/10 | | |
NCT01355068: A Study to Assess if Epanutin Infatabs 50 mg From Germany Are Similar to Dilantin Infatabs 50 mg From Australia |
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| Completed | 1 | 26 | RoW | Epanutin Infatabs (Phenytoin), Dilantin Infatabs (Phenytoin) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Healthy | 06/11 | 06/11 | | |
NCT01635829: A Study to Investigate the Potential Pharmacokinetic Interactions Between Phenytoin or Carbamazepine and Telaprevir |
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| Completed | 1 | 24 | Europe | Telaprevir, Phenytoin, Carbamazepine | Janssen Infectious Diseases BVBA | Healthy Participants | 08/12 | 09/12 | | |
NCT01680042: Clinical Effect of Phenytoin Mucoadhesive Paste on Wound Healing After Oral Biopsy |
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| Unknown status | 1 | 40 | RoW | Phenytoin paste, Placebo | Shahid Beheshti University of Medical Sciences | Wound Healing, Pain | 03/13 | | | |
| Completed | 1 | 21 | US | Oxcarbazepine (brand name vs generic drugs), Divalproex Sodium (brand name vs generic drugs), Carbamazepine (brand name vs generic drugs), Lamotrigine (brand name vs generic drugs), levetiracetam (brand name vs generic drugs), Topiramate (brand name vs generic drugs), Zonisamide (brand name vs generic drugs), Phenytoin sodium (brand name vs generic drugs) | Food and Drug Administration (FDA), University of Maryland, Baltimore | Epilepsy | 08/18 | 09/18 | | |
NCT04845646: DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD. |
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| Completed | 1 | 24 | US | ASC41, Itraconazole, Phenytoin | Gannex Pharma Co., Ltd. | Healthy, NAFLD | 06/21 | 06/21 | | |
SPI-POZ-103, NCT04981704: A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants |
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| Completed | 1 | 74 | US | Poziotinib, Itraconazole, Phenytoin, Paroxetine, Paxil ® | Spectrum Pharmaceuticals, Inc | Healthy | 06/21 | 08/21 | | |
NCT04956627: A Study to Assess the Effect of Itraconazole, Phenytoin and Gemfibrozil on the Drug Levels of BMS-986166 in Healthy Participants |
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| Completed | 1 | 15 | US | BMS-986166, Itraconazole, Sporanox, Extended Phenytoin Sodium, Dilantin, Gemfibrozil, Lopid | Bristol-Myers Squibb | Healthy Participants | 04/22 | 04/22 | | |
NCT05901714: A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam |
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| Recruiting | 1 | 50 | US | Afimetoran, BMS-986256, Phenytoin, Midazolam | Bristol-Myers Squibb | Healthy Participants | 10/23 | 10/23 | | |
NCT05995249: A Study of the Interaction of TAK-279 With Substances That Have an Impact on Metabolism in Healthy Adults |
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| Completed | 1 | 172 | US | TAK-279, Erythromycin, Phenytoin, Efavirenz | Takeda | Healthy Volunteers | 12/23 | 12/23 | | |
NCT06379958: Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects |
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| Recruiting | 1 | 36 | Europe | leramistat 40mg, Itraconazole 200 mg, Phenytoin 100 Mg Oral Capsule, Simvastatin 40mg | Modern Biosciences Ltd | Pharmacokinetics | 05/24 | 09/24 | | |
NCT06466473: A Study to Learn How Different Forms of The Study Medicine Called Phenytoin Are Taken up Into the Blood in Healthy Adults |
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| Not yet recruiting | 1 | 34 | NA | Phenytoin (Ascoli), Phenytoin (Vega Baja) | Pfizer | Healthy | 11/24 | 11/24 | | |
