| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap |
| Not yet recruiting | 4 | 46 | | | Prof Philip Bardin | Severe asthma, Vocal cord Dysfunction | | | | |
| Active, not recruiting | 4 | 58 | | | Allergan Pty Ltd, Allergan Pty Ltd | Chronic pelvic pain | | | | |
ACTRN12605000559617: A double blind randomised, placebo-controlled trial evaluating the effect of Botox injected into the pelvic floor of women with chronic pelvic pain and levator spasm. |
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| Completed | 4 | 60 | | | Allergan Australia Pty Ltd, Allergan Australia Pty Ltd | Chronic pelvic pain and levator spasm. | | | | |
| Recruiting | 4 | 20 | | | John Trantalis, Orthocentre | Elbow Contracture | | | | |
NCT00717782: Pain Relief for Thrombosed External Haemorrhoids |
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| Completed | 4 | 30 | Europe | injection of botulinum toxin, botox injection, injection of saline, saline injection | University of Palermo | Thrombosed External Hemorrhoid | 12/05 | 01/06 | | |
NCT00827736: Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure |
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| Completed | 4 | 73 | Europe | Botox, ISDN ointment, Placebo | Onze Lieve Vrouwe Gasthuis | Anal Fissure | 03/06 | 03/06 | | |
NCT00434863: Comparative Study of the Effect of Dysport and Botox |
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| Completed | 4 | 24 | Europe | botulinum toxin type A | Laserklinik Karlsruhe | Aging | | 03/06 | | |
NCT00430196: BOTOX® Versus Zanaflex® for the Treatment of Post-Stroke or Traumatic Brain Injury Upper Limb Spasticity |
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| Completed | 4 | 135 | US | BOTOX®, Zanaflex® | Icahn School of Medicine at Mount Sinai, Allergan | Upper Limb Spasticity | | 09/06 | | |
NCT00527202: Efficacy Study of Botox to Treat Neuropathic Pain |
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| Completed | 4 | 29 | Europe | botulinum toxin A, saline (placebo) | Hospital Ambroise Paré Paris | Postherpetic Neuralgia, Nerve Trauma | 03/07 | 03/07 | | |
NCT00168480: A Study Using Botulinum Toxin Type A in Patients With Axillary Hyperhidrosis |
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| Completed | 4 | 424 | US, Europe | Botulinum Toxin Type A, BOTOX® | Allergan | Hyperhidrosis | 04/07 | 04/07 | | |
NCT00168415: A Study Using Botulinum Toxin Type A in Adolescents With Axillary Hyperhidrosis |
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| Completed | 4 | 144 | US, Canada | Botulinum Toxin Type A, BOTOX® | Allergan | Hyperhidrosis | 06/07 | 06/07 | | |
NCT00194623: Botox as a Treatment for Chronic Male Pelvic Pain Syndrome |
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| Terminated | 4 | 30 | US | Botulinum Toxin A (Botox) | University of Washington, Paul G. Allen Family Foundation | Chronic Male Pelvic Pain Syndrome | | 08/07 | | |
NCT00959907: Comparison of Two Commercial Preparations of Botulinum Toxin Type A |
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| Completed | 4 | 29 | RoW | BOTULINUM TOXIN TYPE-A, BoNT A1 = Dysport, BoNT A2 = Botox | Brazilan Center for Studies in Dermatology | Wrinkles in Frontal Area | 11/07 | 12/07 | | |
NCT00989768: Field of Effects of Two Commercial Preparations of Botulinum Toxin Type A |
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| Completed | 4 | 29 | RoW | Botulinum Toxin Type A (Dysport®), Botulinum Toxin Type A/Botox®, Botulinum Toxin Type A/Dysport® | Brazilan Center for Studies in Dermatology | Wrinkles in Frontal Area | 11/07 | 12/07 | | |
| Completed | 4 | 65 | Europe | Botulinum Toxin Type A 900kDa, BOTOX®, Botulinum Toxin Type A 150kDa, Xeomin® | Allergan | Blepharospasm | 01/08 | 01/08 | | |
| Unknown status | 4 | 64 | Europe | Botulinum toxin | Rigshospitalet, Denmark | Vulvar Vestibulitis, Vulvar Diseases | | 06/08 | | |
NCT00320281: Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. |
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| Completed | 4 | 19 | US | botulinum toxin A, Botox-A, placebo, normal saline dose based on muscles to be injected, multiple injections may occur based on treatment plan. Injection occur at one single clinical visit. | Craig Hospital, The Craig H. Neilsen Foundation, Allergan | Spinal Cord Injury, Pain | 08/08 | 08/08 | | |
NCT00477802: Botulinum Toxin Type A (Botox) in the Management of Levodopa-Induced Peak-Dose Dyskinesias in Parkinson's Disease |
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| Terminated | 4 | 8 | US | Botulinum Toxin Type A, Placebo | University of Cincinnati, Allergan | Parkinson Disease | 11/08 | 12/08 | | |
NCT00432055: Effects of Botulinum Toxin Type A in Adults With Cerebral Palsy |
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| Completed | 4 | 66 | Europe | Botulinum toxin type A (Botox), placebo (saline) | Sunnaas Rehabilitation Hospital, The Royal Norwegian Ministry of Health | Cerebral Palsy | 01/09 | 01/09 | | |
NCT00432341: Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia |
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| Terminated | 4 | 54 | RoW | botulinum toxin type A, BOTOX®, Dysport® | Allergan | Spasmodic Torticollis | 03/09 | 06/09 | | |
NCT00856414: Patient Satisfaction With Treatment of BOTOX® Cosmetic for the Temporary Correction of Moderate to Severe Glabellar Lines |
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| Completed | 4 | 45 | US | botulinum toxin Type A, BOTOX® | Allergan | Skin Aging | 04/09 | 04/09 | | |
NCT00194610: Botox as a Treatment for Interstitial Cystitis in Women |
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| Completed | 4 | 20 | US | Botox, Botulinum Toxin A, normal saline | University of Washington, Paul G. Allen Family Foundation | Painful Bladder Syndrome, Interstitial Cystitis | 06/09 | 09/10 | | |
NCT00528541 / 2006-006449-14: Comparison of Efficacy and Safety of Two Different Types of Botulinum Toxin Type A in Moderate to Severe Cervical Dystonia |
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| Completed | 4 | 145 | Europe, RoW | botulinum toxin type A, BOTOX®, Dysport® | Allergan | Spasmodic Torticollis | 09/09 | 09/09 | | |
2005-004685-17: A prospective placebo controlled study of botulilium toxin (BOTOX) on gait disorder induced by spastic equinovarus foot. |
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| Completed | 4 | 12 | Europe | BOTOX, Powder and solvent for solution for injection, BOTOX | CUB - Hôpital Erasme | Spastic equinus foot is a common dynamic deformity in patients with cerebral palsy. This dynamic deformity, mainly caused by spasticity of the soleus, gastrocnemius and tibialis posterior muscles, may lead to gait impairment. | | | | |
| Completed | 4 | 274 | Canada, Europe | Botulinum Toxin Type A 900kD, BOTOX®, Placebo | Allergan | Muscle Spasticity | 01/10 | 07/10 | | |
NCT00178646: Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity |
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| Completed | 4 | 33 | US | Botox, generic name: botulinum toxin type A | The University of Texas Health Science Center, Houston, Allergan | Stroke, Brain Injuries, Spasticity | 03/10 | 03/10 | | |
| Withdrawn | 4 | 0 | Europe | Botox, Saline | Sheffield Children's NHS Foundation Trust | Leg Length Inequality, Foot Deformities | 03/10 | 05/10 | | |
NCT01004042: Quality of Life and Self-esteem After Botox® Injections in Depressed and Non-depressed Patients |
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| Completed | 4 | 50 | RoW | Botulinum Toxin Type A, Botox® | Brazilan Center for Studies in Dermatology, Allergan | Depression, Quality of Life | 03/10 | 04/10 | | |
NCT00773253: Botox for Cervical Dystonia Following EMG Mapping |
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| Completed | 4 | 10 | US | Botulinum toxin A, Botox | University of California, San Francisco, Allergan | Cervical Dystonia | 10/10 | 01/11 | | |
NCT00856999: Botox Cosmetic and the Young Patient With Glabellar Furrows |
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| Completed | 4 | 50 | NA | Botox | Oregon Health and Science University, Allergan | Glabellar Furrows | 11/10 | 11/10 | | |
2007-003138-41: Ensayo clínico para evaluar la seguridad de la toxina botulínica inyectada en esfínter uretral externo vía transperineal (esfinterotomía química) en la retención urinaria crónica secundaria a una lesión medular. |
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| Completed | 4 | 20 | Europe | Powder for solution for injection, Botox | Hospital Universitario Vall d’Hebron. Barcelona. Spain | Tratamiento de la retención urinaria secundara a lesión medular. | | | | |
NCT00950664: A Study to Compare Dysport® and Botox® in the Treatment of Cervical Dystonia |
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| Completed | 4 | 103 | RoW | Dysport® (abobotulinumtoxinA), Dysport® (abobotulinumtoxinA)injection, Botox® (onabotulinumtoxinA), Botox® (onabotulinumtoxinA)injection | Seoul National University Hospital, Ipsen, Medical Research Collaborating Center, Seoul, Korea | Cervical Dystonia | 01/11 | 07/11 | | |
| Completed | 4 | 224 | Europe | botulinum toxin type A, Vistabel®, BOTOX® Cosmetic, Bocouture® | Allergan | Glabellar Lines | 01/11 | 04/11 | | |
NCT00404417: Botulinum Toxin A for the Treatment of Chronic Lumbar Back Pain |
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| Unknown status | 4 | 160 | US | Botulinum Toxin A / Placebo, Botox, Botulinum Toxin A / Botulinum Toxin A, Placebo / Botulinum Toxin A, Placebo / Placebo, Placebo | Walter Reed Army Medical Center | Chronic Low Back Pain | 02/11 | 02/11 | | |
2010-018345-64: Evaluation of the efficacy of Xeomin in the treatment of cervical dystonia (CD) and blepharospasmus (BS) in patients who did not respond to treatment with Botox. |
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| Completed | 4 | 30 | Europe | Powder for solution for injection, XEOMIN, BOTOX | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI | cervical dystonia, blepharospasmus (BS) | | | | |
NCT01421719: Safety and Efficacy of botulinumA Toxin (BotoxA) for Treatment of Neurogenic Bladder of Parkinson's Disease |
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| Completed | 4 | 20 | US | Cystoscopic injection of Botox into the urinary bladder, Botox A (Allergan, Inc) | Stanford University, Allergan | Parkinson's Disease, Neurogenic Bladder, Urinary Incontinence, Clostridium Botulinum Toxin Adverse Reaction | 05/11 | 07/11 | | |
NCT01071096: Calcitonin Gene-related Peptide Levels in Chronic Migraine |
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| Completed | 4 | 20 | US | OnabotulinumtoxinA, Botulinum Toxin Type A Purified Neurotoxin Complex, Botox, Saline, Placebo | Cady, Roger, M.D., Allergan | Chronic Migraine | 06/11 | 06/11 | | |
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NCT00908050: Study of the Safety and Efficacy of Botox in Bruxism |
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| Completed | 4 | 23 | US | Botulinum toxin type A, Botulinum toxin type A (Botox), Placebo arm | Baylor College of Medicine, Allergan | Bruxism | 08/11 | 09/11 | | |
NCT00669474: Unicentric Comparing Study of Suction Curettage With Standard BOTOX Injection in the Treatment of Patients With Essential Axillar Hyperhidrosis: Comparing of Efficacy, Duration of Effectiveness, and Adverse Events. |
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| Terminated | 4 | 25 | Europe | Suction curettage, Treatment with Botox | University Hospital, Ghent, Allergan | Essential Axillary Hyperhidrosis | 08/11 | 08/11 | | |
NCT00384371: Pilot Study to Assess the Efficacy of Botulinum Toxin A Treatments on Pain and Disability in Sub-Acute Low Back Pain |
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| Terminated | 4 | 0 | US | Botulinum Toxin A, Botox, Placebo | United States Department of Defense | Low Back Pain | 09/11 | 09/11 | | |
JUVE_BTX, NCT01269801: Study of BOTOX and JUVEDERM for Treatment of Moderate to Severe Facial Wrinkles and Folds |
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| Completed | 4 | 156 | US, Canada | onabotulinumtoxinA, Europe Investigative Sites:, VISTABEL® (Botulinum toxin type A) for Injection, JUVÉDERM, EU Investigative Sites:, JUVÉDERM® Ultra 2 and JUVÉDERM® Ultra 3 Injectable Gel | AboutSkin Dermatology and DermSurgery, PC, Allergan | Wrinkles | 09/11 | 02/12 | | |
| Completed | 4 | 30 | US | Juvederm XC, Botox | Skin Care and Laser Physicians of Beverly Hills | Brow Ptosis | 10/11 | 10/11 | | |
NCT01391312: Patient Satisfaction Study of BOTOX® Cosmetic in the Treatment of Moderate to Severe Frown Lines |
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| Completed | 4 | 40 | US | botulinum toxin Type A, BOTOX® Cosmetic, Vistabel®, Vistabax®, normal saline (placebo) | Allergan | Glabellar Frown Lines | 10/11 | 10/11 | | |
ABO ONA, NCT01732809: Fields Of Effects Of Two Commercial Preparations Of Botulinum Toxin Type A At Equal Labeled Unit Doses |
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| Completed | 4 | 19 | RoW | AbobotulinumtoxinA (ABO), Dysport®, OnabotulinumtoxinA (ONA), Botox® | Brazilan Center for Studies in Dermatology | Skin Wrinkling | 11/11 | 11/11 | | |
NCT01297634: Radial Diffusion of the Botulinum Toxin Type A (Botox®): Electromyographic Evaluation of the Frontal Muscle |
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| Completed | 4 | 64 | RoW | Botulinum Toxin Type-A (day 0) | Ivo Pitanguy Institute, Allergan | Wrinkles | 11/11 | 11/11 | | |
| Completed | 4 | 40 | RoW | BOTOX-A®, Generic Name: Botulinum toxin type A | The Catholic University of Korea, Bobath Memorial Hospital | Muscle Spasticity, Stroke | 12/11 | 05/12 | | |
NCT01272414: Use of Botox in the Management of Thyroid Related Upper Eyelid Retraction |
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| Withdrawn | 4 | 0 | Canada | Botulinum Toxin Type A, BoTox, Saline injection, Placebo | University of Toronto, Allergan | Graves Ophthalmopathy | 01/12 | 02/12 | | |
| Unknown status | 4 | 60 | US | Botox, Saline Solution | Capital Clinical Research Associates, LLC | Major Depression | 06/12 | 06/12 | | |
| Completed | 4 | 280 | Europe | -, -, Powder for solution for injection, Botox | Leiden University Medical Center, Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO), Allergan Pharmaceuticals | Patients suffering from chronic migraine and medication overuse Patienten met chronische migraine en overgebruik van medicatie, Patients suffering from headache on more than 14 days per month of which at least 8 are migraine-days and overusing migraine and/or pain medication. Patienten met hoofdpijn op meer dan 14 dagen per maand waarvan minimaal 8 migraine-dagen en overgebruik van migraine- en/of pijn medicatie., Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT01045694: Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint |
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| Terminated | 4 | 8 | US | Botulinum Toxin Type A, Botox Cosmetic, Botox, Steroid - Triamcinolone Acetonide, Kenalog-40, Lidocaine, Xylocaine | University of Missouri-Columbia | Arthritis Multiple Joint | 08/12 | 10/15 | | |
NCT01529788: Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study |
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| Completed | 4 | 90 | US | Right lateral orbital injection of Botox Cosmetic or Dysport, Botox Cosmetic, Dysport, Left lateral orbital injection of Botox Cosmetic or Dysport | The Maas Clinic, Medicis Pharmaceutical Corporation | Intrinsic Aging of Skin, Solar Elastosis | 09/12 | 09/14 | | |
2012-005068-82: An alternative approach for treatment of infantile esotropia with botulinum toxin A. |
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| Ongoing | 4 | 40 | Europe | Botox, RVG 32957, Powder for solution for injection, Botox | The Rotterdam Eye Hospital, Stichting Wetenschappelijk Onderzoek Oogziekenhuis – Prof. Dr. Flieringa (SWOO) | infantile esotropia, infantile esotropia, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT01777620: A Study of Subject Satisfaction With BOTOX® Cosmetic Treatment in Facial Rhytides |
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| Completed | 4 | 125 | Canada | onabotulinumtoxinA, botulinum toxin Type A, BOTOX®, BOTOX® Cosmetic, Normal Saline | Allergan | Facial Rhytides | 05/13 | 07/13 | | |
NCT01501500: Effect of Botulinum Toxin to Hallux Valgus in Addition to Total Contact Insole |
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| Completed | 4 | 25 | RoW | BOTOX, BOTOX (Allergan, Irvine, CA), Normal Saline (0.9% NaCl) | Chang Gung Memorial Hospital, National Science Council, Taiwan | Hallux Valgus | 08/13 | 08/13 | | |
| Completed | 4 | 66 | Europe | Botox infiltration, botox infiltration, and grup solving terapy group, Psychology therapy, Problem solving group therapy, Botox infiltration & psychology therapy, Botox infiltration and problem solving group therapy. | University Rovira i Virgili, Catalan Institute of Health, Universidad Nacional de Educación a Distancia | Fibromyalgia | 09/13 | 02/14 | | |
NCT01500668: Botulinum Toxin A for Treatment of Catocholamine Induced Finger Necrosis |
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| Unknown status | 4 | 20 | RoW | Botox, Placebo | Sheba Medical Center | Catocholamine Induced Finger Necrosis | 12/13 | 12/13 | | |
| Completed | 4 | 66 | Europe, RoW | botulinum toxin type A, botox | Hospital Ambroise Paré Paris | Postherpetic Neuralgia, Diabetic Polyneuropathies, Other Polyneuropathies | 01/14 | 01/14 | | |
NCT02009540: Botulinum Toxin in the Treatment of Idiopathic Detrusor Overactivity |
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| Unknown status | 4 | 60 | Europe | Botulinum toxin injected to bladder body, Botulinum toxin, Onabotulinumtoxin, Botox, Botulinum toxin injected into trigone | Mr HD Flood | Overactive Detrusor | 01/14 | | | |
2013-003842-18: Prevention of renal and bladder damage in children with spina bifida by means of early injections with Botulinum-Toxin-A (Botox): a pilot study. Preventie van nier- en blaasschade bij kinderen met spina bifida door middel van vroegtijdige injecties met Botulinum-Toxin-A (Botox): een pilotstudie. |
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| Terminated | 4 | 10 | Europe | BOTOX, Intravesical solution/solution for injection, BOTOX | Erasmus MC, Jaap Schouten Foundation | Neurogenic bladder function disease in spina bifida patients. Neurogene blaasfunctiestoornis bij spina bifida patiënten., Spastic bladder in spina bifida patients. Spastische blaas bij patiënten met spina bifida., Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16] | | | | |
NCT01814670: Treatment With Botulinum Toxin Type A (BOTOX®) in Chinese Patients With Moderate to Severe Frown Lines |
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| Completed | 4 | 185 | RoW | botulinum toxin Type A, BOTOX®, onabotulinumtoxinA | Allergan | Glabellar Rhytides | 07/14 | 10/14 | | |
NCT01700387: A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency |
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| Completed | 4 | 20 | US | onabotulinumtoxinA, Botox, Botulinum Toxin Type A Purified Neurotoxin Complex, Topiramate, Topamax, Placebo | Cady, Roger, M.D., Allergan | Chronic Migraine | 08/14 | 08/14 | | |
| Completed | 4 | 250 | US | IncobotulinumtoxinA, Xeomin®, NT201, Botulinum toxin type A [150 kDa], free from complexing proteins, OnabotulinumtoxinA, Botox® | Merz North America, Inc. | Glabellar Frown Lines | 08/14 | 11/14 | | |
NCT01833130: Use of a Treatment Benefit Questionnaire in Patients With Chronic Migraine Treated With OnabotulinumtoxinA (BOTOX®) |
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| Completed | 4 | 52 | US | OnabotulinumtoxinA, botulinum toxin Type A, BOTOX®, Normal saline (placebo) | Allergan | Chronic Migraine | 09/14 | 09/14 | | |
NCT02147561: A Safety and Efficacy Study of BOTOX® in Korean Adults With Chronic Migraine |
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| Completed | 4 | 280 | RoW | botulinum toxin Type A, BOTOX®, onabotulinumtoxinA | Allergan | Migraine Disorders | 02/15 | 02/15 | | |
NCT03048383: Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis |
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| Completed | 4 | 71 | NA | OnabotulinumtoxinA Injectable Product, Botox, AbobotulinumtoxinA Injectable Product, Dysport, Incobotulinumtoxin A Injectable Product, Xeomin | University of Utah | Facial Nerve Injuries, Facial Paresis Associated With Facial Nerve Dysfunction, Facial Asymmetry, Synkinesis | 03/15 | 03/15 | | |
NCT02176356: Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study) |
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| Completed | 4 | 116 | US | onabotulinumtoxinA, botulinum toxin Type A, bimatoprost ophthalmic solution 0.03%, LATISSE®, JUVÉDERM® ULTRA XC, JUVÉDERM® ULTRA PLUS XC, JUVÉDERM® VOLUMA® XC | Allergan | Facial Rhytides, Crow's Feet Lines, Glabellar Lines, Nasolabial Fold | 05/15 | 05/15 | | |
NCT02472210: The Use of Botox in Advanced Parkinson's Patients Experiencing Pain |
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| Unknown status | 4 | 14 | NA | Botulinum Toxin, Botox | University Health Network, Toronto | Parkinson's Disease | 07/15 | 09/15 | | |
| Completed | 4 | 10 | US | Botox, Botulinum Toxin Type A, MYOBLOC, Botulinum Toxin Type B | Georgetown University, Solstice Neurosciences | Spasticity Secondary to Either a Disorder or Trauma, Spinal Cord Injury (SCI), Brain Injury, Tumor, Stroke | 08/15 | 08/15 | | |
NCT02037425: Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine |
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| Completed | 4 | 44 | US | onabotulinumtoxinA, Botox | Cady, Roger, M.D., Allergan | Chronic Migraine | 09/15 | 09/15 | | |
2013-002896-17: Functional evaluation of two therapy concepts: dynamic orthoses and BoNT Funktionelle Evaluierung von zwei Theraphiekonzepten: dynamischen Orthesen und BoNT |
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| Completed | 4 | 40 | Europe | Botulinumtoxin-A, 1-23699, Powder and solvent for solution for injection, Botulinumtoxin-A (BOTOX) | Orthopädisches Spital Speising, Orthopädisches Spital Speising | Infantile cerebral palsy Infantile Zerebral Parese, Infantile cerebral palsy Infantile Zerebral Parese, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
COMPEL, NCT01516892: A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine |
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| Completed | 4 | 716 | US, RoW | onabotulinumtoxinA, BOTOX®, botulinum toxin Type A | Allergan | Migraine Disorders | 11/15 | 11/15 | | |
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2009-015620-29: The efficacy of the Botulinum toxin-A on the manual abilities in children with congenital spastic hemiplegia. Interest of the measure of the bimanual task performance. |
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| Completed | 4 | 30 | Europe | BOTOX, 9060X, Injection*, BOTOX | | The main objective of this study is to investigate the effect of Botulinum toxin A to improve the Upper Limb dysfunction in Hemiplegic Cerebral Palsy Children and in particular, its impact on Upper limb activity performance and how this might be translate in bimanual activities. | | | | |
2004-004633-33: local botox administration on patients with vulvar vestbulitis |
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| Completed | 4 | 64 | Europe | Botox, Botox | Sexological Clinic, Rigshospitalet | Vulvar vestibulits | | 09/08 | | |
2004-004589-33: Tratamiento del dolor cervical crónico secundario a síndrome del latigazo cervical con toxina botulínica tipo A: estudio piloto. Estudio de fase IV, randomizado, a doble ciego y controlado con placebo. |
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| Ongoing | 4 | 36 | Europe | BOTOX, 8881727, | Rehabilitation Department. Hospital mútua de Terrassa | LATIGAZO CERVICAL | | | | |
2005-001378-29: A double blinded randomised controlled trial of injection of botulinum toxin versus normal saline into the puborectalis muscle in patients with pelvic floor dyssynergia. |
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| Ongoing | 4 | 20 | Europe | Botox, Botox, Botox | Bradford Teaching Hospitals NHS Foundation Trust | Obstructed defeacation | | | | |
2005-006169-15: A Double-Blind, Randomised, Cross-over, Safety and Efficacy Pilot Study Comparing Two Botulinum Toxin Type-A Products in the Treatment of Moderate to Severe Cervical Dystonia. |
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| | 4 | 66 | Europe | BOTOX, Xeomin, Botulinum Toxin Type A, Clostridium Botulinum Neurotoxin, | Allergan Limited | Cervical dystonia is the most common form of focal dystonia prevalent at a rate of 89 per million individuals. Sustained involuntary contractions of the neck muscles, lead to painful and disabling neck spasms with abnormal postures of the head. | | 09/07 | | |
| Ongoing | 4 | 64 | Europe | Botulinum Toxin A, BOTOX, BOTOX | Guy\'s & St Thomas\' NHS Foundation Trust | Sensory Urinary Urgency. This is a condition where patients have urinary urgency (sudden desire to urinate which cannot be deferred) /- urge incontinence (urine leakage) and usually is accompanied by frequency (frequent passage of urine; usually > 8/day); and nocturia (passing urine at night ie getting up from sleep). No abnormal bladder muscle overactivity, however, is present. | | | | |
2007-004650-93: The effect of Botulinum toxin A injections for overactive bladder on detrusor contractility |
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| Ongoing | 4 | 10 | Europe | botulinum toxin A, BOTOX ®, BOTOX ® | University Medical Center Groningen | Neurogenic or idiopathic overactive bladder, not adequately responding to anticholinergic therapy | | | | |
2006-000833-36: The Action of Botox® on Urgency – A precise evaluation of its impact on urodynamic parameters during bladder filling in patients with non-neurogenic Overactive Bladder (OAB). |
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| Ongoing | 4 | 14 | Europe | BOTOX, BOTOX | Sheffield Teaching Hospitals NHS Foundation Trust | Non-neurogenic Overactive Bladder (OAB) | | | | |
2007-003017-14: A comparison of the effect of Atropine and Botulinum-toxin in patients with severe drooling |
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| Ongoing | 4 | 40 | Europe | Botox, Atropin Chauvin, M03AX01, S01FA01, Botox, Atropin Chauvin, Botox, Atropin Chauvin | Käkkliniken, Universitetssjukhuset i Linköping | Patients with ALS, Parkinson´s disease, brain-damage cerebral paralysis or other neurological conditions often have an impaired swallowing, resulting in drooling. This adds a social handicap and often also causes facial dermatitis, especially around the mouth. | | | | |
2008-000769-49: Unicentrische vergelijkende studie van suctie curretage met standaard BOTOX injectie bij de behandeling van patiënten met essentiële axillaire hyperhidrosis: vergelijking van efficaciteit, duur van effect, en optreden van bijwerkingen |
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| Completed | 4 | 25 | Europe | Botox, Botox, Botox | University Hospital Ghent | behandeling van axillaire hyperhydrosis | | 08/11 | | |
2004-002981-39: Randomised trial of detrusor botulinum toxin injection (BOTOX®) compared to placebo in women with idiopathic detrusor overactivity |
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| Ongoing | 4 | 240 | Europe | BOTOX®, N/A, BOTOX, BOTOX | University Hospitals of Leicester NHS Trust | Detrusor overactivity which is a disease of bladder function where unprovoked contractions of the detrusor muscle are generated during the storage phase of micturition. Symptoms include frequency, urgency, urge incontinence, nocturia. The first line treatment for this condition is with oral anticholinergic medication, which in many patients is ineffective. | | | | |
2008-004584-19: Skolioser hos cerebral parese patienter behandlet med Botulinum toxin AInjektioner. |
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| Ongoing | 4 | 33 | Europe | botox, botox, botox | University hospital of Hvidovre | Scoliosis in patients with cerebral palsy | | | | |
2008-000853-37: Botulinum Toxin: an adjunct in limb reconstruction – can it reduce pain and joint complications in the lengthening phase? |
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| | 4 | 36 | Europe | Botox, Botox | Sheffield Children\'s NHS Foundation Trust | The surgery to correct leg & foot deformities in children is a lengthy, & sometimes, difficult procedure. Metal frames are attached to the leg and / or foot and over a period of time the frame is manipulated to obtain the corrected position. During this period the muscles & skin become very tight which causes pain & may pull the joint out of position. | | 06/09 | | |
2009-009357-22: A phase IV randomised, placebo controlled, double-blind, single centre, out-patient trial to investigate the functional benefit of botulinum toxin injections combined with physiotherapy treatment for spasticity of the upper limb after stroke |
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| Completed | 4 | 30 | Europe | not applicable, not applicable, BOTOX, BOTOX | University College London | upper limb spasticity after stroke | | 04/14 | | |
2009-009868-31: Quality of life, gross motor function, and actual everyday physical activity level in children with spastic Cerebral Palsy: (cost)effectiveness of combined treatment with multilevel botulinum-toxin injections and intensive functional physiotherapy. |
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| Ongoing | 4 | 60 | Europe | Botox, NDC 0023-1145-01, Botox, Botox | ZonMW | Spastic Cerebral Palsy, GMFCS levels I-III | | | | |
2008-005819-18: A comparison of Dysport (100 U/ml) and Botox (100 U/ml) using dose conversion factor 3:1 and 1.7:1 in the treatment of cervical dystonia. |
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| Ongoing | 4 | 75 | Europe | Botox, Dysport, Botox, Dysport, Botox, Dysport | Department of Neuroscience, Uppsala University | Cervical dystonia, not multifocal or generalised dystonia. | | | | |
2009-013684-19: Studie av botulinumtoxiners anhidrotiska (svettreducerande) effekt beroende på använd koncentration. |
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| Ongoing | 4 | 20 | Europe | Botox, Dysport, Xeomin, Neurobloc, Botox, Dysport, Xeomin, Neurobloc, Botox, Dysport, Xeomin, Neurobloc | Uppsala läns landsting | Studien kommer att utföras på friska försökspersoner. Anhidrotisk (svettreducerande) effekt samt durationen av denna kommer att undersökas efter injektioner med botulinumtoxin.Resultaten från studien kommer senare att appliceras vid behandling av patienter med sjukdomen hyperhidros. | | | | |
| Ongoing | 4 | 30 | Europe | Botox, Botox | Heli Sätilä, Army School of Health | Peripheral intravenous catheter failure, Shock, haemorrhage | | | | |
2010-020057-13: Proof-of-concept-study to Evaluate the Efficacy and Tolerability of Repeated Versus Single Treatment with Botulinum-Toxin (Vistabel®) Treatment in Combination with a Hyaluronic Acid (Juvederm-Ultra® 2) in Patients with Glabellar Frown Lines |
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| Completed | 4 | 40 | Europe | Vistabel, Vistabel | Dermatologikum Hamburg | moderate to severe glabellar frown lines | | 01/12 | | |
2011-004636-66: Development of a method for the measuremnet of botulinumtoxin injection in the facial muscles Utveckling av en metod att mäta effekten av botulinumtoxininjektioner i ansiktsmuskulatur |
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| Completed | 4 | 16 | Europe | VISTABEL, VISTABEL | Uppsala University Hospital, Baau Therapeutics AB | The treatment of glabellar lines in healthy women by muscle paralysis from injection of botulinum toxin Behandling av “arghetsrynkor” hos friska kvinnor genom muskelparalys med botulinum toxin. | | 12/12 | | |
2012-002938-37: NA Comprobación del efecto clínico de tres toxinas botulínicas tipo A, sobre líneas verticales del entrecejo (líneas glabelares). |
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| Ongoing | 4 | 60 | Europe | Vistabel, Bocouture, Azzalure, Vistabel, Bocouture, Azzalure, Powder and solution for solution for injection, Vistabel®, Bocouture®, Azzalure® | DR. JAVIER ANIDO RUBIO, Merz Pharma S.A | NA Se trata de sujetos que requieren tratamiento con toxina botulínica para las arrugas del entrecejo (líneas glabelares) de moderadas a profundas., NA Sujetos con arrugas en el entrecejo a los cuales se les tratará con toxinas botulínicas tipo A, Not possible to specify | | | | |
NCT01486264: Open-Label Non-Inferiority Study Evaluating the Efficacy and Safety of Xeomin® in Subjects With Cervical Dystonia Flex |
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| Completed | 4 | 283 | US | Xeomin®, botulinum toxin, botulinum toxin type A | Merz Pharmaceuticals GmbH, Merz North America, Inc. | Cervical Dystonia | 03/16 | 03/16 | | |
2015-001680-40: Bladder instillation of Botox with iontophoresis for overactive bladder - a pilot study |
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| Completed | 4 | 15 | Europe | Botox, Powder for injection, Botox | Vestfold Hospital, Vestfold Hospital, South-Eastern Norway Regional Health Authority | Overactive bladder, Overactive bladder means a sudden, strong urge to void, often associated with incontinence of urine, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] | | | | |
COMFORT, NCT01945489: OnabotulinumtoxinA (BOTOX®) Treatment for Urinary Incontinence in Patients With Overactive Bladder |
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| Completed | 4 | 254 | US | onabotulinumtoxinA, BOTOX®, botulinum toxin Type A, Normal saline | Allergan | Overactive Bladder | 05/16 | 01/17 | | |
NCT02601287: A Safety and Efficacy Study of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korean Patients |
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| Completed | 4 | 168 | RoW | Botulinum Toxin Type A, BOTOX®, onabotulinumtoxinA | Allergan | Urinary Incontinence, Overactive Bladder | 07/16 | 07/16 | | |
NCT02829281: Intra-articular Botox Type A Versus Corticosteroids in Knee Osteoarthritis |
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| Unknown status | 4 | 105 | RoW | Botulinum Toxin Type A, Triamcinolone hexacetonide, Saline | Federal University of São Paulo | Knee Osteoarthritis | 10/16 | 12/16 | | |
| Completed | 4 | 16 | US | Botox injection, Neurotoxin, Physical Therapy, Transcranial magnetic stimulation (TMS) | University of Florida, American Academy of Neurology, National Ataxia Foundation, American Brain Foundation | Cervical Dystonia | 01/17 | 01/17 | | |
NCT02228863: Upper Extremity Rehabilitation Using Robot and Botulinum Toxin |
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| Unknown status | 4 | 348 | RoW | Early Inmotion and Botox, Botox, then Inmotion, Inmotion, then Botox, Late Inmotion and Botox | National Rehabilitation Center, Seoul, Korea | Stroke, Spasticity | 02/17 | | | |
2016-001378-13: A randomized, sham-controlled trial which compare the deep brain stimulation of a specific brain region against a conventional botulinum toxine treatment for cervical dystonia. Eine randomisierte, scheinkontrollierte Studie, die die tiefe Hirnstimulation eine speziellen Hirnregion mit einer herkömmlichen Botulinumtoxintherapie bei zervikaler Dystonie vergleicht. |
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| Ongoing | 4 | 66 | Europe | Botulinumtoxin Type A, Powder for solution for injection, Botox(R) 50, Botox(R) 100, Botox(R) 200, Dysport(R) 300, Dysport(R) 500, XEOMIN(R) 50, XEOMIN(R) 100 | University Hospital Wuerzburg, Federal Ministry of Education and Research (BMBF), Medtronic GmbH | cervical dystonia zervikale Dystonie, Torticollis spasmodicus Schief- bzw. Fehlhaltung des Halses, Diseases [C] - Nervous System Diseases [C10] | | | | |
