| Botox (onabotulinumtoxin A) / GSK, AbbVie, Healis Therap |
NCT04631588: Intradermal (ID) BOTOX in the Treatment of Facial Fine Lines |
|
|
| Completed | 1b | 172 | US | Botox, Placebo | Allergan | Facial Fine Lines | 11/21 | 11/21 | | |
ACTRN12611000077965: Healthy Volunteer Study to Determine the Safety and Tolerability of MT10109 (Clostridium Botulinum Toxin Type A) in Comparison to Botox(Registered Trademark) |
|
|
| Completed | 1 | 20 | | | Medytox, Inc, Medytox, Inc | Muscle relaxation in Extensor Digitorum Brevis muscle | | | | |
NCT00175604: Comparative Trial of Botox in the Management of Children With Congenital Muscular Torticollis |
|
|
| Withdrawn | 1 | 0 | Canada | Botox | University of British Columbia | Torticollis | 02/08 | 02/08 | | |
NCT00279903: Is Botox Effective in Relieving Pain From Knee Osteoarthritis? |
|
|
| Completed | 1 | 62 | US | Botulinum toxin type A (Btx-A), Botox, Cortisone, Medrol | Mayo Clinic | Osteoarthritis, Knee | 08/08 | 08/08 | | |
| Terminated | 1 | 8 | US | intramuscular Botox versus oral baclofen | Vanderbilt University | Spasticity | 02/09 | 02/09 | | |
NCT00529386: Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) |
|
|
| Terminated | 1 | 7 | Canada | Botox, Botulinem toxin | Queen's University, Allergan | Prostatitis, Chronic Pain Syndrome | 09/09 | 12/09 | | |
Botox/Rehab, NCT00565201: Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients |
|
|
| Completed | 1 | 25 | US | Botox and rehab, Placebo and rehab | Emory University, Allergan | Stroke | 12/09 | 12/11 | | |
NCT00976443: Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects |
|
|
| Completed | 1 | 60 | US | BTA, Botox, Placebo (normal saline) | Mayo Clinic | Obesity | 09/11 | 09/11 | | |
| Completed | 1 | 31 | US | BOTOX | Plastic Surgery Professional Association, Allergan | Vaginismus | 12/12 | 12/12 | | |
NCT03796351: Pharmacodynamic and Safety of MT10107(Botulinum Type A Neurotoxin) in Comparison to BOTOX® |
|
|
| Completed | 1 | 25 | RoW | MT10107, Coretox, Botox | Medy-Tox | Healthy Volunteers | 01/13 | 01/13 | | |
NCT02403219: Paralysis of the Orbicularis Muscle of the Eye in the Treatment for Dry Eye |
|
|
| Completed | 1 | 20 | RoW | Botulinum toxin type A injection, Botox, Saline solution injection, Saline solution | Instituto de Oftalmología Fundación Conde de Valenciana | Dry Eye Syndromes | 02/14 | 01/15 | | |
NCT01520441: BOTOX in Men With Prostate Cancer With Lower Urinary Tract Symptoms(LUTS)/Benign Prostatic Hyperplasia (BPH) |
|
|
| Withdrawn | 1 | 0 | US | BOTOX, onabotulinumtoxinA | The University of Texas Health Science Center, Houston | Prostate Cancer, Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms (LUTS) | 03/14 | 03/14 | | |
| Completed | 1 | 20 | Canada | Botox, Onabotulinum Toxin A | Mount Sinai Hospital, Canada | Scrotal Pain | 04/14 | 04/14 | | |
NCT01682733: Endoscopic Gastric Reduction for Weight Management |
|
|
| Completed | 1 | 10 | US | Botulinum toxin, Botox, Overstitch Endoscopic Suturing System | Mayo Clinic | Obesity | 12/14 | 12/14 | | |
| Completed | 1 | 8 | US | injection of botulinum toxin type A., Botox. | University of Minnesota, Allergan | Psoriasis Vulgaris | 06/15 | 12/15 | | |
NCT02173405: Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain |
|
|
| Completed | 1 | 10 | US | OnabotulinumtoxinA, Botox, Placebo | University Hospitals Cleveland Medical Center, Allergan | Myofascial Pain Syndromes, Myofascial Trigger Point Pain, Trigger Point Pain, Myofascial | 09/15 | 09/16 | | |
NCT02202070: Botox for Treatment of TMJ Disorder With Bruxism |
|
|
| Withdrawn | 1 | 0 | US | onabotulinumtoxinA, BOTOX | Washington University School of Medicine | Temporomandibular Joint Disorders, Bruxism, Temporomandibular Joint Dysfunction Syndrome, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint | 12/15 | 12/15 | | |
NCT03103594: Comparison of the Treatment of Refractory Bladder Pain Syndrome With DMSO and DMSO With Botulinum Toxin A |
|
|
| Completed | 1 | 2 | NA | DMSO, Botox | University of Pennsylvania, Society for Urodynamics and Female Urology | Bladder Pain Syndrome | 08/16 | 04/17 | | |
NCT02524236: Effect of 50 and 100 IU Doses of Botox A Toxin Injection in BPH Patients. |
|
|
| Completed | 1 | 40 | RoW | Botox injection in the prostate, transrectal injection of the prostate | Beni-Suef University | Benign Prostatic Hyperplasia | 11/16 | 11/16 | | |
NCT05164003: CORETOX® in Treatment of Post Stroke Upper Limb Spasticity (Phase1) |
|
|
| Completed | 1 | 30 | RoW | CORETOX®, BOTOX® | Medy-Tox | Muscle Spasticity | 09/17 | 09/17 | | |
NCT03317717: Pharmacodynamic and Safety of MEDITOXIN® in Healthy Male Volunteers |
|
|
| Completed | 1 | 25 | RoW | Meditoxin, Botox | Medy-Tox | Healthy | 01/18 | 01/18 | | |
NCT03371342: Treatment of MEDITOXIN® in Female Patients With Idiopathic Overactive Bladder |
|
|
| Completed | 1 | 30 | RoW | Meditoxin, Botox | Medy-Tox | Overactive Bladder | 05/18 | 09/18 | | |
NCT03186547: Satisfaction Of Adult Patients With Gummy Smile Treated By Botulinum Toxin A Injection |
|
|
| Unknown status | 1 | 22 | NA | Botulinum Toxin A Injection, BOTOX, Modified Lip Repositioning Surgery | Cairo University | Gummy Smile Due to Hypermobile Upper Lip | 06/18 | 06/18 | | |
NCT02008136: New Approaches in Evaluating Patients' Response to Botulinum Toxins in the Treatment of Chronic Neck Pain and Back Pain |
|
|
| Unknown status | 1 | 60 | US | Botulinum Toxins, Botox, Myobloc | VA Connecticut Healthcare System | Cervicalgia, Low Back Pain | 08/18 | 12/18 | | |
NCT03547141: Pharmacodynamic and Safety of MBA-P01 in Healthy Male Volunteers |
|
|
| Completed | 1 | 28 | RoW | MBA-P01, BOTOX | Medy-Tox | Healthy | 08/18 | 11/18 | | |
NCT03647982: Anhidrotic Area and Safety of MEDITOXIN in Healthy Male Valunteers |
|
|
| Completed | 1 | 13 | RoW | Meditoxin, Botox | Medy-Tox | Anhidrotic Area, Hyperhidrosis | 10/18 | 11/18 | | |
NCT03069911: Trial of OnabotulinumtoxinA for Depression in Parkinson Disease |
|
|
| Terminated | 1 | 3 | US | OnabotulinumtoxinA, Botox, Botulinum Toxin Type A, Control, Normal saline | Johns Hopkins University | Parkinson Disease, Depression | 05/19 | 06/19 | | |
NCT03616262: "Efficacy of Botulinum Toxin Injection in Reducing Limb Pain in Patients With Complex Regional Pain Syndrome" |
|
|
| Unknown status | 1 | 20 | US | Botox + Lidocaine, Lidocaine alone | VA Connecticut Healthcare System, Allergan | Complex Regional Pain Syndrome | 12/19 | 12/19 | | |
NCT04439825: Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction |
|
|
| Completed | 1 | 45 | US | Botulinum Neurotoxin, Placebo | DeNova Research | Mood | 09/20 | 12/20 | | |
NCT04030767: Evaluating Lip Repositioning for the Treatment of Excess Gingival Display With and Without Pretreatment With Botox |
|
|
| Not yet recruiting | 1 | 22 | NA | Botox Injectable Product, Xeomin | Cairo University | Gingival Overgrowth | 09/20 | 09/22 | | |
NCT04467450: Ultrasound Guided Botulinum Toxin Type A Injection of Subacromial-Subdeltoid Bursa in Hemiplegic Shoulder Pain |
|
|
| Recruiting | 1 | 36 | RoW | botulinum toxin type A, botox 100 IU, Methyl Prednisolonate, Depomedrol 40mg /2ml | Benha University | Subacromial Bursitis, Subdeltoid Bursitis | 11/20 | 12/20 | | |
NCT03346252: The Effect of Botulinum Toxin A on Headache Attributed to TMD |
|
|
| Completed | 1 | 20 | US | Botulinum Toxin type A, Botox | State University of New York at Buffalo | Secondary Headache Disorder | 03/21 | 03/21 | | |
NCT04715048: Split-Face Study Comparing Botox and Jeuveau in Treating Glabellar Lines |
|
|
| Active, not recruiting | 1 | 20 | US | PrabotulinumtoxinA, Jeuveau, Onabotulinum toxin A, Botox | University of Southern California | Glabellar Frown Lines | 05/25 | 06/25 | | |
NCT04523506: The Effects of Botulinum Toxin on Oral Aperture in Patients With Scleroderma |
|
|
| Completed | 1 | 17 | US | Botulinum toxin(Botox) | University of Texas Southwestern Medical Center | Scleroderma | 04/21 | 04/21 | | |
NCT04186442: Evaluate the Safety and Efficacy of Botulax® Versus Botox® in Patient With Overactive Bladder |
|
|
| Completed | 1 | 38 | RoW | Botulinum toxin type A injection, Botulax®, Botulinum Toxin Type A Injection [Botox], Botox® | Hugel | Overactive Bladder | 04/21 | 10/21 | | |
NCT04171258: Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia |
|
|
| Completed | 1 | 38 | RoW | Botulinum toxin type A injection, Botulax®, Botulinum Toxin Type A Injection [Botox], Botox® | Hugel | Cervical Dystonia | 04/21 | 10/21 | | |
| Completed | 1 | 38 | RoW | Botulinum Toxin Type A Injection [Botox], Botox®, Botulinum toxin type A injection [HG-102], HG-102 | Hugel | Glabellar Lines | 09/21 | 12/21 | | |
| Completed | 1 | 15 | US | Transvaginal botulinum toxin A (BTA) injection, Botox® 100 units | Stanford University, Society for Urodynamics & Female Urology Foundation | Overactive Bladder, Bladder, Overactive, Urge Incontinence, Urgency Urinary, Urinary Frequency/Urgency | 09/21 | 09/21 | | |
NCT03236012: Hyperhidrosis in Patients With Amputations-Botox |
|
|
| Completed | 1 | 25 | US | Botulinum Toxin Type A (Botox), Manual Muscle Testing (MMT), Labs (CBC, BMP, PFT'S, (FEV1 & FVC)), Iodine Starch Skin Test | University of Utah, US Department of Veterans Affairs, U.S. Army Medical Research and Development Command | Hyperhidrosis | 01/22 | 02/22 | | |
NCT04970407: A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants |
|
|
| Completed | 1 | 45 | Europe | Botulinum toxin type A, abobotulinumtoxinA (Dysport®), onabotulinumtoxinA (Botox®), incobotulinumtoxinA (Xeomin®) | Ipsen | Healthy Participants | 03/22 | 06/22 | | |
NCT05292638: Safety and Efficacy of CKDB-501A in Subjects With Moderate-to-severe Glabellar Lines |
|
|
| Completed | 1 | 30 | RoW | CKDB-501A, Botox® | CKD Bio Corporation | Glabellar Lines | 06/22 | 06/22 | | |
NCT05083286: Duration of Botox Using OLD Versus COLD for Treatment of Glabellar Lines |
|
|
| Recruiting | 1 | 40 | US | OnabotulinumtoxinA, Botox | Clinical Testing of Beverly Hills, Allergan | Glabellar Frown Lines | 08/22 | 08/22 | | |
NCT05428930: Safety and Efficacy of CKDB-501B in Subjects With Moderate-to-severe Glabellar Lines |
|
|
| Completed | 1 | 30 | RoW | CKDB-501B, Botox®50U | CKD Bio Corporation | Glabellar Lines | 10/22 | 10/22 | | |
NCT05382767: Safety and Efficacy of CKDB-501A in Subjects With Post-stroke Upper Limb Spasticity |
|
|
| Completed | 1 | 24 | RoW | CKDB-501A, Botox® | CKD Bio Corporation | Post-stroke Upper Limb Spasticity | 12/22 | 12/22 | | |
NCT05496335: A Study to Evaluate Sequential Administration of AGN-151586 and OnabotulinumtoxinA (BOTOX) Injections in Adult Participants for Treatment of Glabellar Lines |
|
|
| Completed | 1 | 90 | US | AGN-151586, BOTOX, OnabotulinumtoxinA, Placebo | AbbVie | Glabellar Lines | 05/23 | 05/23 | | |
NCT04917731: Botulinum Toxin Type A for Cold Intolerance Secondary to Digital Amputations and Replantations: A Pilot Study |
|
|
| Enrolling by invitation | 1 | 28 | US | Botulinum toxin type A, Botox | Massachusetts General Hospital, Allergan | Cold Intolerance | 06/23 | 06/23 | | |
NCT05766683: Depth of Botulinum Neurotoxin Injection for Treatment of Glabellar Lines |
|
|
| Active, not recruiting | 1 | 20 | US | onabotulinumtoxinA at a depth of 2mm, onabotulinumtoxinA at a depth of 4mm | Henry Ford Health System | Glabellar Frown Lines | 06/23 | 12/25 | | |
NCT07292025: Phase 1 Trial of JTM201 in Subjects With Post-stroke Upper Limb Spasticity |
|
|
| Completed | 1 | 30 | RoW | JTM201 in normal saline, BOTOX 100U in normal saline | Jetema Co., Ltd. | Upper Limb Spasticity Post-Stroke | 04/24 | 09/24 | | |
NCT06212960: Evaluate the Safety and Explore the Efficacy of DWP712 With Moderate to Severe Glabellar Lines |
|
|
| Completed | 1 | 20 | RoW | DWP712, BOTOX® | Daewoong Pharmaceutical Co. LTD. | Glabellar Lines | 02/24 | 03/24 | | |
NCT02019004: A Pilot Study Testing Onabotulinum Toxin a Versus Incobotulinum Toxin a Injections for Facial Wrinkles |
|
|
| Active, not recruiting | 1 | 20 | US | Onabotulinum Toxin A, Botox, Incobotulinum Toxin A, Xeomin | Northwestern University | Wrinkles | 12/25 | 12/25 | | |
NCT05807412: Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides |
|
|
| Completed | 1 | 10 | US | PrabotulinumtoxinA-Xvfs, Jeaveau, OnabotulinumtoxinA, Botox | Lupo Center for Aesthetic and General Dermatology, Evolus, Inc. | Rhytides | 02/24 | 02/24 | | |
NCT06013644: Acupuncture, Dry Needle and Botox Injection in Management of Patient With Myofascial Pain Dysfunction Syndrome |
|
|
| Recruiting | 1 | 39 | RoW | Acupuncture needle, Dry needle, Botox Injectable Product | Cairo University | Myofascial Trigger Point Pain, Myofascial Pain Syndrome | 02/24 | 02/24 | | |
ChiCTR2300074351: Clinical research of botulinum toxin A in reducing scar hyperplasia after correction of epicanthus |
|
|
| Recruiting | 1 | 40 | | 0.9% sodium chloride injection ;Injection of botox | Shenzhen Hospital of Peking University; Shenzhen Hospital of Peking University, Project funds by Shenzhen Hospital of Peking University | scar hyperplasia | | | | |
NCT05769478: Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinA |
|
|
| Completed | 1 | 21 | US | Amifampridine, Firdapse | Wake Forest University Health Sciences | Botulism, Iatrogenic Botulism | 10/24 | 10/24 | | |
ChiCTR2300068735: A prospective cohort study of the efficacy and safety of BOTOX-A versus surgery for the treatment of Acute Concomitant Esotropia (AACE) |
|
|
| Not yet recruiting | 1 | 80 | | None ;None | TIANJIN EYE HOSPITAL; Tianjin Eye Hospital, The Open Fund of the Institute of Ophthalmology of Nankai University （nkykk202208） | Acute Concomitant Esotropia (AACE) | | | | |
| Enrolling by invitation | 1 | 10 | US | Bladder chemodenervation (Botox), Bladder Sham (Saline) Injection Procedure | University of Washington | Spinal Cord Injuries | 04/28 | 09/28 | | |
NCT04630873: Low or High Botox Dilution for the Hemiplegic Gait? |
|
|
| Recruiting | 1 | 20 | Europe | Botulinum toxin, gait analysis, medicapteurs Win-Track, RehaGait Pro | University of Ioannina | Post Stroke Spastic Hemiplegia | 08/25 | 08/25 | | |
NCT04984317: Feasibility of BOTOX Injection on Improving Female Stress Urinary Incontinence |
|
|
| Suspended | 1 | 20 | US | onabotulinumtoxin A, BOTOX | Northwell Health, Allergan | Stress Urinary Incontinence | 04/25 | 08/25 | | |
| Active, not recruiting | 1 | 5 | US | Transvaginal botulinum toxin A (BTA) injection, Botox® 100 units | Stanford University, McCormick and Gabilan Faculty Fellowship Award | Interstitial Cystitis, Bladder Pain Syndrome | 02/25 | 02/25 | | |
NCT04580238: Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache |
|
|
| Withdrawn | 1 | 80 | Canada | Botox 200 UNT Injection, onabotulinum toxin a, Non Botox based Standard of Care Treatments for Headache/Migraine | University of Alberta | Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis, Carotid Dissection Artery, Vertebral Dissection Artery, Hemorrhagic Stroke, Reversible Cerebral Vasoconstriction Syndrome | 01/25 | 06/25 | | |
NCT06778421: Impact of OnabotulinumtoxinA (BOTOX®) on Stress |
|
|
| Recruiting | 1 | 20 | US | Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Botulinum Toxin A, BTA, Sodium Chloride | Center for Advanced Facial Plastic Surgery | Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic, Stress, Psychological Cumulative, Stress, Physiological, Stress Response, Stress Levels, Stress Perception | 07/25 | 09/25 | | |
2004-002369-19: Behandling af savlen hos børn med cerebral parese ved anvendelse af botulinum toksin i spytkirtler |
|
|
| Completed | 1 | 20 | Europe | BOTOX, Powder for injection*, BOTOX | Hvidovre Hospital | Børn med cerebral parese har ofte problemer med savlen, primært på grund af nedsat synkefunktion. | | | | |
NCT06834789: A Study to Assess the Adverse Events of Intramuscular Injections of AGN-151586 and OnabotulinumtoxinA in Adult Participants for the Change of Glabellar Lines (GL) |
|
|
| Completed | 1 | 132 | US | AGN-151586, OnabotulinumtoxinA, Placebo | AbbVie | Glabellar Lines | 11/25 | 11/25 | | |
| Recruiting | 1 | 30 | US | Botulinum neurotoxin, High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device | University of Miami, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Pelvic Floor Disorders | 03/27 | 03/27 | | |
AD, NCT06928246: The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis |
|
|
| Recruiting | 1 | 8 | US | Onabotulinum Toxin Type A - Phase 1b, Onabotulinum Toxin Type A - Phase 2 | Daniel Kaplan, Almirall, S.A. | Atopic Dermatitis (AD) | 12/25 | 01/26 | | |
NCT05956509: Study of Intramuscular Injections of ABBV-950 to Assess Adverse Events and Change in Disease Activity in Adult Participants With Upper Limb Spasticity |
|
|
| Terminated | 1 | 1 | US | ABBV-950, Botulinum toxin type A, BOTOX, OnabotulinumtoxinA, Placebo for ABBV-950 | AbbVie | Upper Limb Spasticity | 06/24 | 06/24 | | |
