Sarcoma  >>  plerixafor  >>  Phase 2
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5 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
plerixafor / Generic mfg.
NCT01621477: T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant

Terminated
2
34
US
clofarabine, Cl-F-Ara-A, CAFdA, Clofarex, Clolar(TM), cytarabine, Ara-C, busulfan, Myleran(R), Busulfex, Plerixafor, AMD3100, Mozobil(R), cyclophosphamide, Cytoxan, antithymocyte globulin (rabbit), Rabbit ATG, Rabbit Thymoglobulin(R), stem cells, HSC infusion, Tacrolimus, FK506, Prograf(R), Protonic(R), mycophenolate mofetil, MMF, CellCept(R)
St. Jude Children's Research Hospital, Assisi Foundation
Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Hodgkin or Non-Hodgkin Lymphoma, Sarcoma, Myeloid
12/15
12/15
NCT03746080: Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Active, not recruiting
2
21
US
Plerixafor, AMD 3100, JM-3100, Mozobil, SDZ SID 791, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac, Whole-Brain Radiotherapy (WBRT), WBRT, whole-brain radiation therapy, whole-brain radiotherapy, Radiation Therapy, XRT, RT
Lawrence D Recht, Sanofi
Glioblastoma, Glioblastoma With Primitive Neuronal Component, Gliosarcoma, Malignant Glioma, Oligodendroglial Component Present
05/22
07/27
NCT01288573 / 2010-019340-40: A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone

Completed
1/2
46
Europe, RoW
plerixafor
Genzyme, a Sanofi Company, Sanofi
Ewing's Sarcoma/Soft Tissue Sarcoma, Neuroblastoma, Brain Tumors
05/17
05/17
NCT01977677: Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade Glioma

Completed
1/2
30
US
radiation therapy, irradiation, radiotherapy, therapy, radiation, temozolomide, SCH 52365, Temodal, Temodar, TMZ, plerixafor, AMD 3100, Mozobil, laboratory biomarker analysis, pharmacological study, pharmacological studies
Lawrence Recht, National Cancer Institute (NCI)
Adult Ependymoblastoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma, Adult Medulloblastoma, Adult Mixed Glioma, Adult Oligodendroglial Tumors, Adult Pineoblastoma, Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
11/17
09/18
NCI-2013-00701, NCT00669669: O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Terminated
1/2
12
US
3-Dimensional Conformal Radiation Therapy, 3-dimensional radiation therapy, 3D CONFORMAL RADIATION THERAPY, 3D CRT, 3D-CRT, Conformal Therapy, Radiation Conformal Therapy, Autologous Hematopoietic Stem Cell Transplantation, Autologous Stem Cell Transplantation, Carmustine, BCNU, Becenum, Becenun, BiCNU, Bis(chloroethyl) Nitrosourea, Bis-Chloronitrosourea, Carmubris, Carmustin, Carmustinum, FDA 0345, Gliadel, N,N'-Bis(2-chloroethyl)-N-nitrosourea, Nitrourean, Nitrumon, SK 27702, SRI 1720, WR-139021, Filgrastim, Filgrastim XM02, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tbo-filgrastim, Tevagrastim, In Vitro-Treated Peripheral Blood Stem Cell Transplantation, in vitro-treated PBPC transplantation, in vitro-treated peripheral blood progenitor cell transplantation, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, O6-Benzylguanine, 6-O-BENZYLGUANINE, O(6)-Benzylguanine, Plerixafor, AMD 3100, JM-3100, Mozobil, SDZ SID 791, Proton Beam Radiation Therapy, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac
Fred Hutchinson Cancer Center
Glioblastoma, Gliosarcoma
07/18
01/21

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