Not yet recruiting

2

98

Europe

Nivolumab, Ipilimumab, Capecitabine, Solution for infusion, Solution for injection, Film-coated tablet, Opdivo, Yervoy, Capecitabine

Centre Léon Bérard, Bristol-Myers Squibb

Triple negative breast cancer patients with residual disease after neoadjuvant chemotherapy Cancer du sein triple négatif et présentant une maladie résiduelle après chimiothérapie néoadjuvante, Breast cancer Cancer du sein, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

90

RoW

Arm A : standard neoadjuvant chemoradiotherapy group, fluoropyrimidine based CCRT -> TME -> adjuvant chemotherapy, Arm B : adjuvant FOLFOX group, Total mesorectal excision (TME) -> 12 cycles of FOLFOX every 2 weeks, or Total mesorectal excision (TME) -> CCRT + 12 cycles of FOLFOX every 2 weeks

Yonsei University

Locally Advanced Rectal Cancer

05/19

08/21

Not yet recruiting

2

60

 

5 - fluorouracilcapecitabine in combination with cisplatin synchronous intensity-modulated radiotherapy (CCRT) ;capecitabine in combination with cisplatin synchronous intensity-modulated radiotherapy(CCRT)

The Second People's Hospital of Neijiang; The Second People's Hospital of Neijiang, Project funding

Nasopharyngeal carcinoma

 

 

Not yet recruiting

2

125

Europe

tesetaxel, Xeloda, DJ-927, Capsule, hard, Film-coated tablet, Xeloda

Odonate Therapeutics, Inc., Odonate Therapeutics, Inc.

breast cancer cáncer de mama, breast cancer cáncer de mama, Diseases [C] - Cancer [C04]

 

 

Ongoing

2

40

Europe

Solution for infusion, Film-coated tablet, Fluorouracil Accord Healthcare 50 mg/ml, solution pour injection ou perfusion, Xeloda 150 mg comprimés pelliculés., Xeloda 500 mg comprimés pelliculés., ELOXATIN 5 mg/ml solution à diluer pour perfusion, Vectibix 20 mg/mL solution à diluer pour perfusion, Elvorine 25 mg/2,5 ml solution injectable Elvorine 50 mg/5 ml solution injectable

Fédération Francophone de Cancérologie Digestive, Belgian Group of Digestive Oncology (BGDO), FFCD itself

metastatic colorectal adenocarcinoma without a RAS mutation adénocarcinome colorectal métastatique sans mutation RAS, patient with a metastatic colorectal cancer Patient présentant un cancer colorectal métastatique, Diseases [C] - Cancer [C04]

 

 

Recruiting

2

25

 

Continuous administration of apatinib 500mg/ days; capecitabine 1000mg/m2, Bid, D1-14, Q3W; after 6 cycles of PD patients without apatinib 500mg/ days + capecitabine 500mg

The Affiliated Tumor Hospital of Guangxi Medical University; The Affiliated Tumor Hospital of Guangxi Medical University, Self-raised

recurrent/metastatic triple-negative breast cancer

 

 

Recruiting

2

120

 

Gemcitabine plus capecitabine ;cisplatin plus capecitabine?

Anhui Provincial Hospital; Anhui Provincial Hospital, scientific research funding of Anhui province hospital

metastatic or locally advanced triple-negative breast cancer

 

 

Not yet recruiting

2

55

Europe

pembrolizumab, MK-3475, Solution for infusion, Concentrate for solution for infusion, CAPÉCITABINE MYLAN, OXALIPLATINE HOSPIRA, Avastin, KEYTRUDA (Pembrolizumab, MK3-475)

Federation Francophone de Cancerologie Digestive, MSD

MICROSATELLITE STABLE (MSS) METASTATIC COLORECTAL CANCER AND A HIGH IMMUNE INFILTRATE, METASTATIC COLORECTAL CANCER WITH SPECIFIC MOLECULAR PROFIL (MSS) AND A HIGH IMMUNE INFILTRATE, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

280

Europe

radiotherapy, capecitabine, oxaliplatin

Uppsala University, Swedish Cancer Society

Rectal Cancer

05/20

06/25

Recruiting

2

138

 

maintenance treatment group of capecitabine ;maintenance treatment group of apatinib combined with capecitabine

Guizhou Province Cancer Hospital Affiliated to Guizhou Medical University; Guizhou Province Cancer Hospital Affiliated to Guizhou Medical University, Self-raised funds

Cervical Carcinom

 

 

Ongoing

2

340

Europe

METFORMINA, XELODA, OXALIPLATINO, aspirina, [657-24-9], [154361-50-9], [63121-00-6], [58-78-2], Tablet, Concentrate for solution for infusion, xeloda, OXALIPLATINO

ISTITUTO NAZIONALE TUMORI - IRCCS FONDAZIONE PASCALE, Istituto Nazionale Tumori - Fondazione G.Pascale, IRCCS Napoli

LOCALLY ADVANCED RECTAL CANCER PATIENTS IN STAGE II/III Pazienti con cancro del retto localmente avanzato in stadio II/III., LOCALLY ADVANCED RECTAL CANCER PATIENTS IN STAGE II/III Pazienti con cancro del retto localmente avanzato in stadio II/III., Diseases [C] - Cancer [C04]

 

 

Completed

2

274

Europe, Canada, US, RoW

BMS-986213, Nivolumab, Opdivo, BMS-936558, XELOX, FOLFOX, SOX

Bristol-Myers Squibb

Gastric Cancer, Cancer of the Stomach, Esophagogastric Junction

08/20

01/24

Not yet recruiting

2

54

Europe

Durvalumab, Oxaliplatin, Fluorouracil, Folinic Acid, capecitabine, Concentrate for solution for infusion, Solution for injection/infusion, Film-coated tablet, Durvalumab

NHS Greater Glasgow and Clyde, The University of Glasgow, , AstraZeneca

Rectal Cancer., Cancer of the lower end of the large bowel., Diseases [C] - Cancer [C04]

 

 

Not yet recruiting

2

400

Europe, RoW

PEMBROLIZUMAB, KEYTRUDA (pembrolizumab, MK-3475), Lenvatinib, Docetaxel EVER Valinject, Docetaxel Amneal, Docetaxel Aurobindo, Capecitabine Accord, Paclitaxel EVER Pharma, Erbitux (Cetuximab), Docetaxel, Capecitabine, Paclitaxel, Cetuximab, MK-3475, E7080/MK-7902, Solution for infusion, Capsule, hard, Concentrate for solution for infusion, Film-coated tablet, KEYTRUDA (pembrolizumab, MK-3475), Docetaxel EVER Valinject, Docetaxel Amneal, Docetaxel Aurobindo, Capecitabine Accord, Paclitaxel EVER Pharma, Erbitux (Cetuximab), Docetaxel, Capecitabine, Paclitaxel, Cetuximab

Merck Sharp & Dohme LLC, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc, Merck Sharp & Dohme LLC, Eisai Limited, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co.,Inc

Recurrent/metastatic head and neck squamous cell carcinoma, Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) which has progressed after treatment with both platinum therapy and most recently immunotherapy, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

102

RoW

Neoadjuvant Chemotherapy, NACT, Laparoscopic gastrectomy, LDG, Open gastrectomy, ODG, Adjuvant Chemotherapy, ACT

Peking University, Beijing Municipal Science & Technology Commission

Gastric Cancer

11/20

11/22

Active, not recruiting

2

25

RoW

SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine

Henan Cancer Hospital

Gastric Cancer

01/24

12/26

Not yet recruiting

2

80

NA

Capecitabine, additional chemotherapy

Zhejiang Cancer Hospital

Breast Cancer

12/20

12/22

Completed

2

64

RoW

Capecitabine plus temozolomide VS Capecitabine, Temoram, Xeloda

Asan Medical Center

Advanced Rectal Cancer

02/21

02/21

Completed

2

33

RoW

Apatinib Combined With Tislelizumab and Chemotherapy, Combined therapy

Renmin Hospital of Wuhan University

Advanced Gastric Adenocarcinoma

03/23

01/24

Recruiting

2

119

RoW

Oxaliplatin and capecitabine, antiemetics, Total Mesorectal Excision, TME

Peking University Cancer Hospital & Institute

Rectal Cancer

04/21

04/24

Active, not recruiting

2

78

RoW

Pyrotinib plus Capecitabine, Irene

Henan Cancer Hospital

HER2 Positive Metastatic Breast Cancer

04/21

12/24

Active, not recruiting

2

144

US

temozolomide, Temodar, capecitabine, Xeloda

ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)

Gastrinoma, Glucagonoma, Insulinoma, Islet Cell Carcinoma, Pancreatic Polypeptide Tumor, Recurrent Islet Cell Carcinoma, Somatostatinoma

05/21

12/24

Not yet recruiting

2

25

Europe

VINORELBINA, Capecitabina, Ciclofosfamide, [VINORELBINA], [Capecitabina], [Ciclofosfamide], Capsule, soft, Tablet

FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS UNIVERSITA' CATTOLICA DEL SACRO CUORE

HER2 negative hormone receptors positive metastatic breast cancer progressed after CDK 4/6 inhibitors Carcinoma della mammella in fase metastatica con recettori ormonali positivi, HER2 negativo in progressione dopo terapia con inibitori delle chinasi cicline dipendenti 4/6, HER2 negative hormone receptors positive metastatic breast cancer progressed after CDK 4/6 inhibitors Carcinoma della mammella in fase metastatica con recettori ormonali positivi, HER2 negativo in progressione dopo terapia con inibitori delle chinasi cicline dipendenti 4/6, Diseases [C] - Cancer [C04]

 

 

Not yet recruiting

2

49

Europe

Lonsurf, oxaliplatin, Tablet, Solution for infusion, Lonsurf, oxaliplatin

GERCOR, Servier

colorectal or oesogastric adenocarcinoma, colorectal or oesogastric adenocarcinoma, Diseases [C] - Cancer [C04]

 

 

Recruiting

2

43

RoW

1. Treatment: IP chemotherapy + Systemic chemotherapy, 2. Response evaluation after 4 cycles of IP + systemic chemotherapy

Gangnam Severance Hospital

Advanced Gastric Cancer, Peritoneal Carcinomatosis

06/21

12/21

Not yet recruiting

2

25

Europe

Retifanlimab, INCMGA00012, Solution for infusion

Academic Medical Center, Incyte

Gastroesophageal cancer Oesophagus- en maagcarcinoom, Gastroesophageal cancer Slokdarm- en maagkanker, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

91

US

Capecitabine, Ro 09-1978/000, Xeloda, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, Nealorin, Novoplatinum, Paraplat, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Fluorouracil, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-FU, AccuSite, Carac, Fluoro Uracil, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Ribofluor, Ro 2-9757, Ro-2-9757, Laboratory Biomarker Analysis, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Quality-of-Life Assessment, Quality of Life Assessment

ECOG-ACRIN Cancer Research Group, National Cancer Institute (NCI)

Anal Basaloid Carcinoma, Anal Canal Cloacogenic Carcinoma, Anal Squamous Cell Carcinoma, Metastatic Anal Canal Carcinoma, Recurrent Anal Canal Carcinoma, Stage IIIB Anal Canal Cancer, Stage IV Anal Canal Cancer

08/21

08/23

Recruiting

2

100

RoW

EGFR antibody and Chemotherapy, Chemotherapy

Shanghai Changzheng Hospital

Gastric Cancer, Cetuximab, Nimotuzumab

08/21

12/21

Not yet recruiting

2

21

Europe

temozolomide, [temozolomide], Capsule, hard

FONDAZIONE IRCCS "ISTITUTO NAZIONALE DEI TUMORI"

Localy advanced low-risk rectal cancer, placed at less then 15 cm form the anal verge and staged as cT = 2 and cN0 or cT1-3 cN1 (TNM classification 8th edition), without evidence of distant metastases (cM0).The study requires central confirmation of tumor molecular status of microsatellitestability by multiplex polymerase chain reaction, lack of MGMT expression by immunohistochemistry (IHC) and evidence of MGMT promoter methylation by pyrosequencing. Adenocarcinoma del retto localmente avanzato a basso rischio, stadiato clinicamente, secondo la classificazione TNM (8° edizione) come cT=2 ed N0 oppure ogni cT1-3 cN1, senza evidenza di metastasi a distanza (cM0) e localizzato a meno di 15 cm dallo sfintere anale esterno. Presenza di stabilità microsatellitare, negatività di espressione immunoistochimica di MGMT sul materiale istologico ed evidenza di metilazione del promotore del gene MGMT in pirosequenziamento., Rectal cancer within 15 cm from the anal verge, without metastases in other organs and surgically resectable, with micro satellite stability and no MGMT gene expression. Tumore nel retto entro 15 cm dallo sfintere anale senza metastasi in altri organi e asportabile chirurgicamente, con stabilità dei microsatelliti e assenza di espressione del gene MGMT., Diseases [C] - Cancer [C04]

 

 

Recruiting

2

30

RoW

Anti-PD-1 antibody, XELOX

China Medical University, China

Gastric or Gastroesophageal Junction Adenocarcinoma, AFP

09/21

09/21

Not yet recruiting

2

158

 

Raltitrexed Combined with Vinorelbine ;Capecitabine Combined with Vinorelbine

The Affiliated Tumor Hospital of Guangxi Medical University; The Affiliated Tumor Hospital of Guangxi Medical University, Self-raised

Advanced Breast Cancer

 

 

Recruiting

2

261

Europe

PAXG, mFOLFIRINOX, short-course chemotherapy, long-course chemotherapy

Associazione Italiana per lo Studio del Pancreas, High Research srl, Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente

Pancreas Ductal Adenocarcinoma

11/21

11/23

Active, not recruiting

2

46

RoW

inetetamab and PD-1 inhibitor combined with chemotherapy.

Henan Cancer Hospital

HER2 Positive Metastatic Breast Cancer

11/21

12/24

Not yet recruiting

2

62

Europe

CAPECITABINE ACCORD, THERASPHERE, Coated tablet, Radiopharmaceutical precursor, solution, CAPECITABINE ACCORD, THERASPHERE

Centre Régional de lutte contre le Cancer Eugène Marquis, Boston Scientific Corporation, Centre Régional de lutte contre le cancer Eugène Marquis

Patients having operable intrahepatic cholangiocarcinoma Patients présentant un cholangiocarcinome intra-hépatique résécable, Biliary tract cancer Cancer des voies biliaires, Diseases [C] - Cancer [C04]

 

 

Active, not recruiting

2

37

US

bevacizumab, Avastin, trastuzumab, Herceptin, oxaliplatin, capecitabine, xeloda

Dana-Farber Cancer Institute, Brigham and Women's Hospital, Massachusetts General Hospital, Genentech, Inc.

Esophageal Cancer, Gastric Cancer

12/21

07/24

Recruiting

2

136

 

Cetuximab combined with capecitabine ;capecitabine alone

Affiliated Hospital of Southwest Medical University; Affiliated Hospital of Southwest Medical University, own expense

left colorectal cancer

 

 

Active, not recruiting

2

25

RoW

PD-1 Antibody, Toripalimab, Oxaliplatin, Capecitabine, External beam radiotherapy, Total mesorectal excision

Sun Yat-sen University

DMMR Colorectal Cancer, MSI-H Colorectal Cancer, Locally Advanced Colorectal Cancer

04/24

12/24

Recruiting

2

112

Europe

CPT-11, Calcio levofolinate, 5-Fluorouracil, Capecitabine, Temozolomide

Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori

Neuroendocrine Carcinoma

01/22

01/22

Not yet recruiting

2

164

Europe

Concentrate for solution for infusion, Powder and solution for solution for injection, Solution for injection/infusion, Film-coated tablet, Irinotecan, OXALIPLATIN, Calcium folinate, FLUORURACIL, Capecitabine

Instituto de Investigación Sanitaria INCLIVA, Instituto de Salud Carlos III

Localised Colon Cancer (stage II-III) Cáncer Colorrectal Localizado (estadio II-III), Colon Cancer (stage II-III) Cáncer Colorrectal (estadio II-III), Diseases [C] - Cancer [C04]

 

 

Not yet recruiting

2

31

Europe

Olaparib, Oxaliplatin, Calcium Folinate, 5-Fluorouracil, Capecitabine, MK-7339, Solution for infusion, Film-coated tablet, Solution for injection, KEYTRUDA (pembrolizumab, MK-3475)

Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus Nordwest, MSD Sharp & Dohme GmbH

metastatic or advanced inoperable Her-2 negative esophagogastric adenocarcinoma, metastatic advanced gastric cancer, Diseases [C] - Cancer [C04]

 

 

Completed

2

60

RoW

Trastuzumab, Oxaliplatin, Capecitabine

Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

Advanced Gastric Carcinoma

02/22

06/23

Active, not recruiting

2

40

US

Erlotinib, Tarceva, capecitabine, Xeloda, Radiation Therapy, gemcitabine, Gemzar, erlotinib

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Genentech, Inc.

Pancreatic Cancer

04/22

04/23

Completed

2

223

RoW

Docetaxel / Capecitabine, Combination chemotherapy group., The chemotherapy regimen will be decided by the treating physician., Capecitabine / Vinorelbine, Paclitaxel / Gemcitabine, Ribociclib, Endocrine treatment arm:, NSAI + goserelin+ ribociclib, Letrozole OR Anastrozole, Goserelin

Novartis Pharmaceuticals

Breast Cancer

04/22

05/23

Not yet recruiting

2

50

RoW

PD-1 antibody, Capecitabine, Xeloda, Irinotecan, Neoadjuvant Radiotherapy

Fudan University

Locally Advanced Rectal Cancer

04/22

12/22

Completed

2

37

US

pembrolizumab, trastuzumab, capecitabine, cisplatin, Oxaliplatin, 5-Fluorouracil, 5-FU

Memorial Sloan Kettering Cancer Center

Esophageal Cancer, Gastric Cancer

06/22

03/23

Recruiting

2

210

RoW

Dendrobium Huoshanense Granules, Pelvic Radiation, Capecitabine, Irinotecan, Placebo

Fudan University

Locally Advanced Rectal Cancer

06/22

12/22

Recruiting

2

91

RoW

Capecitabine-Oxaliplatin-Irinotecan-Bevacizumab Combination

First Affiliated Hospital of Zhejiang University

Unresectable Metastatic Colorectal Carcinoma

06/22

06/23

Active, not recruiting

2

108

RoW

JS001, PD-1 antibody, Oxaliplatin, S1, Capecitabine, XELODA

Sun Yat-sen University, Shanghai Junshi Bioscience Co., Ltd.

Gastric Cancer, Locally Advanced Solid Tumor

06/22

10/24

Recruiting

2

73

 

Capecitabine/Oxaliplatin (XELOX Regimen) in Combination with Regorafenib and PD-1 Monoclonal Antibody

Shanghai Oriental Hospital; Shanghai Oriental Hospital, East Clinical Center of Oncology, ECCO

HER2-negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

 

 

Recruiting

2

60

RoW

Paclitaxel/DDP, Group A, XELOX/SOX, Group B

Peking Union Medical College Hospital

Locally Advanced Gastric Cancer

08/22

08/23