2009-015895-87: Application of zileuton (Zyflo CR) in patients with Sjögren Larsson Syndrome |
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| Ongoing | 3 | 20 | Europe | zileuton, Zyflo CR, Zyflo CR | UMC St Radboud | Sjögren Larsson syndrome (SLS) is an autosomal recessive inherited neurometabolic disorder which is characterized by a clinical triad of congenital ichthyosis, spastic di- or tetraplegia and mental retardation. A disturbance of lipid metabolism due to deficiency of the microsomal fatty aldehyde dehydrogenase (FALDH) underlies SLS. | | | | |