| donepezil / Generic mfg. |
2005-003789-40: A randomized, four-way cross-over, double-blind, controlled study of oral donepezil (2, 5, 10 mg) in patients with moderate to severe obstructive sleep apnea. |
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| Ongoing | 2 | 30 | Europe | donepezil, donepezil, Aricept, Aricept | Pharmapnea AB | Moderate to severe obstructive sleep apnea. Males and females; aged 25 to 65 years, previously diagnosed OSA defined as an oxygen desaturation (4%) index of 15 or more per hour of sleep obtained from a preceding routine outpatient screening recording. | | | | |
2005-004215-30: Imaging the neural correlates of cholinergic and behaviour driven rehabilitation in patients with Wernicke’s aphasia: a double-blinded, cross-over, randomised controlled trial. |
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| Ongoing | 2 | 60 | Europe | PR1, PR2, PR1, PR2, Aricept 5mg, Aricept 5mg (x2 tabs to give 10mg), Aricept 5mg, Aricept 5mg (x2 tabs to give 10mg) | Joint Sponsorship: University College London (UCL) & University College London Hospitals (UCLH) | Wernicke\'s aphasia caused by a stroke | | | | |
| Ongoing | 2 | 400 | Europe | AN06DA02, Arizept, Arizept | Technische Universität München, Fakultät für Medizin, Klinikum rechts der Isar | Postoperative delirium | | | | |
2008-001940-38: Functional RMN study to evaluate the prompt and middle term effect of the treatment with Donepezil in patients affected by multiple sclerosis and mild impairment of cognitive function. |
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| Ongoing | 2 | 30 | Europe | ARICEPT, ARICEPT | OSPEDALE S. RAFFAELE | patients affected by multiple sclerosis | | | | |
2008-006337-27: A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBOCONTROLLED,PARALLEL GROUP STUDY TO EVALUATE THEEFFICACY AND SAFETY OF PRX-03140 AS MONOTHERAPY INSUBJECTS WITH ALZHEIMER’S DISEASE |
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| Ongoing | 2 | 75 | Europe | PRX-03140, Aricept, Aricept | EPIX Pharmaceuticals, Inc. | Alzheimer\'s Disease | | | | |
2008-008481-12: Tratamiento de la Afasia Post-ictus con Donepezilo y Rehabilitación Grupal Intensiva de la Afasia: Análisis de la Reorganización Funcional de la Redes del Lenguaje con Neuroimagen Estructural y Funcional.Treatment of post-stroke aphasia with donepezil and constraint-induced aphasia therapy: Analysis of functional reorganization of language networks with structural and functional neuroimaging |
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| Ongoing | 2 | 15 | Europe | ARICEPT FLAS 10 mg, comprimidos bucodispersbles, ARICEPT FLAS 10 mg, comprimidos bucodispersbles | Marcelo L. Berthier Torres | Tratamiento de la Afasia crónica con DonepeziloTreatment of chronic aphasia with Donepecil | | | | |
ChiCTR1800014316: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study to Evaluate the Efficacy and Safety of Benfotiamine Tablets in Patients with Mild-to-moderate Altheimer's Disease Treated with Donepezil Hydrochloride |
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| Recruiting | 2 | 300 | | 600 mg benfotiamine ;300 mg benfotiamine ;placebo | Huashan hospital of fudan university; Shanghai Rixin Biological Co., Ltd, 2014ZX09101005-005 | Alzheimer's disease | | | | |
NCT03907371: The Effect of Donepezil in Radiotherapy-related Cognitive Impairment. |
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| Recruiting | 2 | 238 | RoW | Donepezil Hydrochloride, Placebo | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Radiation Injuries, Cognitive Impairment | 12/22 | 12/22 | | |
2022-001751-17: Study evaluating the efficacy and safety of donepezil versus placebo in mild cognitive impairment associated with Parkinson's disease Estudio de evaluación de la eficacia y la seguridad del donepezilo versus placebo en el deterioro cognitivo leve asociado a la Enfermedad de Parkinson |
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| Not yet recruiting | 2 | 120 | Europe | Tablet, Aricept | Institut de Recerca Hospital de la Santa Creu i Sant Pau - IIB Sant Pau, Instituto de Salud Carlos III | Parkinson's disease Enfermedad de Parkinson, Parkinson's disease Enfermedad de Parkinson, Diseases [C] - Nervous System Diseases [C10] | | | | |
| Recruiting | 2 | 20 | US | Donepezil, Placebo oral tablet, Topical Zinc Oxide | University of Maryland, Baltimore | Wound Heal | 07/23 | 07/23 | | |
| Completed | 2 | 77 | Europe | DONEPEZIL, PLACEBO | University Hospital, Clermont-Ferrand, Federation Francophone de Cancerologie Digestive | Digestive Oncology, Supportive Care | 01/24 | 01/24 | | |
NCT04507438: The Effect of Donepezil on Glycemic Control in Type II Diabetics |
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| Terminated | 2 | 7 | US | Donepezil 5-10 Mg Oral Tablet, Placebo Oral Tablet | University of Maryland, Baltimore | Diabetes Mellitus, Type 2 | 09/23 | 09/23 | | |
2021-005326-23: Evaluation of the efficacy of donepezil in the treatment of oxaliplatin-induced peripheral neuropathy EVALUATION DE L’EFFICACITE DU DONEPEZIL DANS LE TRAITEMENT DES NEUROPATHIES PERIPHERIQUES INDUITES PAR L’OXALIPLATINE |
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| Not yet recruiting | 2 | 80 | Europe | DONEPEZIL, Tablet, Donepezil | CHU de Clermont-Ferrand, Institut National du Cancer (INCa) | Oxaliplatine-induced peripheral neuropathy Neuropathie périphérique induite par l'oxaliplatine, Oxaliplatine-induced peripheral neuropathy Neuropathie périphérique induite par l'oxaliplatine, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT06518941: An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa |
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| Not yet recruiting | 2 | 10 | US | Donepezil | New York State Psychiatric Institute | Anorexia Nervosa | 12/25 | 12/25 | | |
NCT06041789: Effect of Acetylcholinesterase Inhibitors on Bone Metabolism |
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| Not yet recruiting | 2 | 45 | US | Donepezil, Placebo | Duke University, National Institute on Aging (NIA) | Osteoporosis | 06/25 | 06/25 | | |
NCT05709301: Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease |
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| Not yet recruiting | 2 | 120 | NA | Donepezil Hydrochloride, Placebo | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | Parkinson Disease, Mild Cognitive Impairment | 11/25 | 11/25 | | |
NCT05042102: Donepezil and Cognitive Training for Alcohol Use Disorder (AUD) |
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| Recruiting | 2 | 160 | US | Donepezil + Cognitive remediation therapy (CRT), Donepezil + Placebo CRT, Placebo medication + Cognitive remediation therapy (CRT), Placebo medication + Placebo CRT | VA Connecticut Healthcare System, Yale University, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Use Disorder | 05/26 | 05/26 | | |
