| donepezil / Generic mfg. |
2021-001788-26: Interest of adding donepezil to the non-medicinal care pathway recommended in France for Alzheimer's disease: CHOLINE-2 study Intérêt de l’adjonction du donepezil à la prise en charge non médicamenteuse par parcours de soin préconisée en France dans la maladie d’Alzheimer: Etude CHOLINE-2 |
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| Not yet recruiting | 4 | 120 | Europe | Tablet | Assistance Publique - Hôpitaux de Paris, ASSOCIATION FRANCE ALZHEIMER ET MALADIES APPARENTEES | Newly diagnosed patient with mild to moderate Alzheimer's disease meeting IWG-2 research diagnostic criteria including positivity for Alzheimer's disease biomarkers. Patient nouvellement diagnostiqué pour une maladie d’Alzheimer à un stade léger ou modéré répondant aux critères diagnostiques de recherche IWG-2 incluant la positivité des biomarqueurs de la maladie d’Alzheimer., Alzheimer's disease Maladie d’Alzheimer, Diseases [C] - Nervous System Diseases [C10] | | | | |
2017-003586-94: Monitoring of changes in the concentration of donepezil (Alzheimer's disease drug), oxidative stress indicators, and acetylcholinesterase enzyme activity in cerebrospinal fluid and plasma of patients with Alzheimer's disease. Sledování změn koncentrace donepezilu (léku na Alzheimerovu chorobu), ukazatelů oxidačního stresu a aktivity enzymu acetylcholinesterásy v mozkomíšním moku a plasmě pacientů s Alzheimerovou chorobou. |
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| Not yet recruiting | 4 | 32 | RoW | Landex, Aricept, Dospelin, Donpethon, Tablet, , Landex, Aricept, Dospelin, Donpethon | Fakultní nemocnice Hradec Králové, Neurologická klinika Fakultní nemocnice Hradec Králové | Alzheimer's disease Alzheimerova choroba, Alzheimer's disease Alzheimerova choroba, Diseases [C] - Nervous System Diseases [C10] | | | | |
PM012-2b, NCT05811000: A Phase 2 Clinical Study to Explore the Optimal Dosage/Administration of PM012 Tablet in Alzheimer's Disease |
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| Recruiting | 2/3 | 312 | RoW | PM012, PM012 Placebo, Donepezil, Donepezil placebo | Mediforum Ltd., Co., LSK Global Pharma Services Co. Ltd. | Mild Alzheimer Disease | 02/21 | 08/24 | | |
2022-001751-17: Study evaluating the efficacy and safety of donepezil versus placebo in mild cognitive impairment associated with Parkinson's disease Estudio de evaluación de la eficacia y la seguridad del donepezilo versus placebo en el deterioro cognitivo leve asociado a la Enfermedad de Parkinson |
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| Not yet recruiting | 2 | 120 | Europe | Tablet, Aricept | Institut de Recerca Hospital de la Santa Creu i Sant Pau - IIB Sant Pau, Instituto de Salud Carlos III | Parkinson's disease Enfermedad de Parkinson, Parkinson's disease Enfermedad de Parkinson, Diseases [C] - Nervous System Diseases [C10] | | | | |
2021-005326-23: Evaluation of the efficacy of donepezil in the treatment of oxaliplatin-induced peripheral neuropathy EVALUATION DE L’EFFICACITE DU DONEPEZIL DANS LE TRAITEMENT DES NEUROPATHIES PERIPHERIQUES INDUITES PAR L’OXALIPLATINE |
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| Not yet recruiting | 2 | 80 | Europe | DONEPEZIL, Tablet, Donepezil | CHU de Clermont-Ferrand, Institut National du Cancer (INCa) | Oxaliplatine-induced peripheral neuropathy Neuropathie périphérique induite par l'oxaliplatine, Oxaliplatine-induced peripheral neuropathy Neuropathie périphérique induite par l'oxaliplatine, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT00457769: Aricept to Improve Functional Tasks in Vascular Dementia |
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| Active, not recruiting | 1 | 18 | US | Donepezil and self-generated memory training, Aricept, Donepezil and experimenter-administered memory training | Kessler Foundation, Pfizer | Stroke, Vascular Dementia, Memory Deficits | 12/21 | 12/21 | | |
| Completed | 1 | 44 | US, RoW | Donepezil, MK-0000, Donepezil hydrochloride, Aricept, Placebo | Merck Sharp & Dohme LLC | Alzheimer's Disease, Mild Cognitive Impairment | 01/23 | 02/23 | | |
NCT05525780: Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Donepezil From Single Dose of GB-5001 IM Depot and Aricept® Oral Tablets in Healthy Male Volunteers |
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| Completed | 1 | 48 | Canada | GB-5001, Placebo, Oral cohort | G2GBio, Inc. | Alzheimer Disease | 06/23 | 06/23 | | |
NCT06285240: Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007) |
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| Active, not recruiting | 1 | 28 | US | MK-1167, Donepezil, Placebo | Merck Sharp & Dohme LLC | Alzheimer's Disease | 09/24 | 09/24 | | |
| Not yet recruiting | 1 | 64 | RoW | Donepezil Dihydroxynaphthalate for Injection, HHT201 | Shanghai Synergy Pharmaceutical Sciences Co., Ltd. | Alzheimer Disease | 03/25 | 03/25 | | |