Digestive System Neoplasms  >>  conatumumab (AMG 655)  >>  Phase 2
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6 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
conatumumab (AMG 655) / Amgen
QUILT-2.018, NCT00813605 / 2008-005301-19: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Completed
2
155
US, Europe, RoW
FOLFIRI, AMG 655, Conatumumab, Placebo, AMG 479
NantCell, Inc.
Metastatic Colorectal Cancer
01/11
06/12
NCT00630786 / 2007-004722-25: Conatumumab/Panitumumab Combination Metastatic Colorectal Cancer Study

Completed
1b/2
53
US, Europe, RoW
Panitumumab, Vectibix®, Conatumumab, AMG 655
Amgen
Colon Cancer, Colorectal Cancer, Rectal Cancer, Metastatic Colorectal Cancer, Oncology
05/09
11/10
QUILT-2.019, NCT00630552: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancer

Checkmark P2 data
Jun 2012 - Jun 2012: P2 data
Checkmark P1/2 data
Sep 2011 - Sep 2011: P1/2 data
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Completed
1b/2
138
US
Placebo, AMG 479, AMG 655
NantCell, Inc.
Adenocarcinoma of the Pancreas, Metastatic Pancreatic Cancer, Pancreatic Cancer
01/10
04/12
NCT00625651: Phase 1b/2 Study of AMG 655 With mFOLFOX6 and Bevacizumab for First-Line Metastatic Colorectal Cancer

Completed
1b/2
202
US
Placebo, AMG 655, Modified FOLFOX6, mFOLFOX6, Bevacizumab
Amgen
Metastatic Colorectal Cancer, Colon Cancer, Colorectal Cancer, Rectal Cancer
08/10
09/11
NCT00819169 / 2008-005074-12: QUILT-3.026: AMG 655 in Combination With AMG 479 in Advanced, Refractory Solid Tumors

Terminated
1b/2
89
US, Europe
AMG 479, AMG 655, AMG 655 is also known as conatumumab.
NantCell, Inc.
Colorectal Cancer, Locally Advanced, Metastatic Cancer, Non-Small Cell Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Sarcoma, Solid Tumors
10/10
10/11
NCT01017822: Conatumumab, Gemcitabine Hydrochloride, Capecitabine, and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Withdrawn
1/2
0
US
conatumumab, capecitabine, gemcitabine hydrochloride, 3-dimensional conformal radiation therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI)
Pancreatic Cancer
 
 

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