| aspirin / Generic mfg. |
NCT02273505: Comparison of Pharmacokinetics of Dipyridamole in Asasantin Extended Release (ER) and in a Combination of Persantin Immediate Release Tablets and ASA Tablets in Healthy Subjects |
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| Completed | 1 | 20 | Europe | Asasantin (ER), Persantin, Acetyl salicylic acid (ASA) | Boehringer Ingelheim | Healthy | 05/00 | | | |
NCT02187562: Effect of Steady State Meloxicam on Low Dose Aspirin Induced Inhibition of Platelet Aggregation and Thromboxane Synthesis in Healthy Males and Females |
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| Completed | 1 | 16 | Europe | Meloxicam, Aspirin | Boehringer Ingelheim | Healthy | 08/02 | | | |
NCT00325715: AGN 201904 Versus Esomeprazole in the Prevention of Aspirin-induced Stomach or Upper Intestinal Damage in Healthy Volunteers |
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| Completed | 1 | 150 | US | AGN 201904, esomeprazole | Allergan | Peptic Ulcer | 08/06 | 08/06 | | |
NCT00442052: To Compare the Gastroprotective Effects and Pharmacokinetic Profile of PA Versus Enteric-Coated Aspirin |
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| Completed | 1 | 80 | US, Canada | aspirin, omeprazole | POZEN | Healthy | | 01/07 | | |
NCT00265408: Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection |
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| Withdrawn | 1 | 0 | US | aspirin, warfarin | University of California, San Diego | Ischemic Stroke | | 03/07 | | |
NCT00363753: Pilot Study of Continuing Aspirin Versus Switching to Clopidogrel After Stroke or Transient Ischemic Attack |
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| Withdrawn | 1 | 0 | US | aspirin versus clopidogrel | University of California, San Diego | Transient Ischemic Attack, Stroke, Aspirin, Clopidogrel | | 03/07 | | |
NCT00441519: A Parallel Group Study to Compare the Gastroprotective Effects of PA 325 Versus 81 mg Enteric Coated Aspirin |
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| Completed | 1 | 80 | US, Canada | aspirin, omeprazole | POZEN | Healthy | 04/07 | 04/07 | | |
NCT00425074: Pharmacodynamic-pharmacokinetic Trial, of Slow Release ASA, in the Platelet Functionalism. |
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| Completed | 1 | 50 | Europe | slow release acetyl salicylic acid, ASA, SR-ASA | Rottapharm Spain | Cardiovascular Disease | 06/07 | 07/07 | | |
NCT00688961: Effects of Omacor and Aspirin on Platelet Function |
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| Completed | 1 | 10 | US | Aspirin, omega-3 acid ethyl esters, Omacor, Lovaza | Sanford Research | Healthy | 08/07 | 08/07 | | |
NCT00442585: S(+)-Ibuprofen Effects on Asprin Treated Volunteers |
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| Completed | 1 | 72 | Europe | S(+)-ibuprofen | Gebro Pharma GmbH | Drug Interactions | | 10/07 | | |
NCT00548678: Platelet Function and Safety After IV and Oral Diclofenac, IV Ketorolac and Oral Aspirin in Adult Volunteers |
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| Completed | 1 | 30 | US | intravenous diclofenac sodium (DIC075V), ketorolac, oral diclofenac (Cataflam), aspirin | Javelin Pharmaceuticals | Healthy | 11/07 | 11/07 | | |
NCT00632086: Evaluate Relative Bioavailability of PA32540 (Asa/Omeprazole), Its Aspirin Component, and Ecotrin® in Healthy Volunteers |
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| Completed | 1 | 36 | US | PA32540, aspirin component of PA32540, Ecotrin | POZEN | Healthy | 02/08 | 02/08 | | |
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NCT01424332: To Evaluate Whether Acetyl Salicylic Acid (Aspirin) and Darexaban (YM150) Interact in Their Effects |
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| Completed | 1 | 24 | Europe | Darexaban, YM150, Acetyl Salicylic Acid (ASA), Aspirin | Astellas Pharma Inc | Pharmacodynamic and Pharmacokinetic Interaction, Healthy Subjects | 03/08 | 03/08 | | |
NCT00258245: Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia |
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| Completed | 1 | 5 | US | ascorbic acid, All Day C CR, Ascot, C Complex, C-500, C-500-Gr, C-Time, Cecon, Cemill 1000, Cemill 500, Centrum Singles-Vitamin C, Cevi-Bid, N Ice with Vitamin C, Special C, Sunkist Vitamin C, Vicks Vitamin C Drops, Vitamin C TR, arsenic trioxide, Trisenox®, bortezomib, Velcade®, dexamethasone, Dexasone, Decadron, Diodex, Hexadrol, Maxidex, Dexamethasone Sodium Phosphate, Dexamethasone Acetate, thalidomide, Thalomid, Aspirin, Acuprin 81, Anacin Aspirin Regimen, Ascriptin, Ascriptin Enteric, Aspergum, Aspidrox, Aspir-Low, Aspir-Mox, Aspir-trin, Aspirtab, Bayer Aspirin, Bufferin, Buffex, Easprin, Ecotrin, Ecpirin, Empirin, Entaprin, Entercote, Fasprin, Genacote, Gennin-FC, Genprin, Halfprin, Magnaprin, Med Aspirin, Migralex, Miniprin, Minitabs, Norwich Aspirin, Ridiprin, Sloprin, St. Joseph Aspirin, Uni-Buff, Uni-Tren, Valomag, Zero-Order Release, Zorprin | Barbara Ann Karmanos Cancer Institute, National Cancer Institute (NCI) | Multiple Myeloma and Plasma Cell Neoplasm | 04/08 | 04/08 | | |
NCT00688428: Study Comparing a Fixed-Dose Capsule of Esomeprazole 40mg and LDA 325mg With Free Combination |
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| Completed | 1 | 84 | US | Esomeprazole 40mg/ASA 325mg, Nexium/Bayer Aspirin, Esomeprazole, Nexium, ASA, Bayer aspirin | AstraZeneca | Ulcers, Upper GI Symptoms | 04/08 | 04/08 | | |
NCT02251795: Effects of Steady State Tipranavir/Ritonavir or Darunavir/Ritonavir or Ritonavir on Platelet Function, Coagulation and Fibrinolysis Biomarkers in Healthy Subjects |
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| Completed | 1 | 52 | US | Tipranavir, APTIVUS®, Ritonavir, Norvir®, Darunavir, PREZISTA®, Aspirin, Acetylsalicylic acid | Boehringer Ingelheim | Healthy | 06/08 | | | |
NCT04008979: Pharmacokinetic and Pharmacodynamic Assessment of a Novel, Pharmaceutical Lipid-Aspirin Complex |
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| Completed | 1 | 32 | NA | Aspirin | PLx Pharma | Bioequivalence | 06/08 | 06/08 | | |
NCT00587496: 30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers |
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| Unknown status | 1 | 60 | US | valacyclovir hydrochloride, Valtrex, placebo, valacyclovir plus aspirin | National Eye Institute (NEI) | Herpes Simplex | 07/08 | 07/08 | | |
PA32540-109, NCT00700687: Study Evaluating the Effect on Gastroduodenal Mucosa of PA32540, PA32540 and Celecoxib, and Aspirin With Celecoxib |
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| Completed | 1 | 90 | US | PA32540, PA32540 and celecoxib, aspirin and [NSAID] | POZEN | Healthy | 07/08 | 07/08 | | |
NCT00566904: New Topical Treatment for Continued Pain After Shingles |
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| Completed | 1 | 30 | US | Epikeia coatings with aspirin, Epikeia coatings with acetylsalicylic acid, Epikeia coatings with lidocaine, Epikeia coatings with local anesthetic, Epikeia coatings alone | Biomedical Development Corporation, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), The University of Texas Health Science Center, Houston | Postherpetic Neuralgia | 08/08 | 09/08 | | |
ChiCTR-TRC-09000483: A Multi-center, Randomized, Double Blinding, Controlled Phase III Clinical Trial of Dl-3-Butylphthalide Injection in the Treatment of Acute Cerebral Infarct |
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| Completed | 1 | 600 | | 1-14 days, NBP injection 25mg/100ml; blank ozagrel, 100ml; intravenous drip (styrene-NBP injecti on 50-70 minutes),2 times/day.15-90days,NBP soft capsules,100mg / pills, 2 / second, 2 times / day.Blank aspirin tablets. ;1-14 days, NBP injection 25mg/100ml; blank ozagrel, 100ml; intravenous drip (NBP injection 50-70 minutes), 2 times/day, 15-90 days, aspirin tablets, 25mg / chip, 4 / time, 1 times / day.blank NBP soft capsules，2 / time, 2 times / day. ;1-14 days, a blank NBP injection 100ml; Ozagrel injection, 100ml: 80mg; intravenous drip (NBP injection 50-70 minutes), 2 times/day, between 6-8 hours. 15-90 days, aspirin tablets, 25mg / chip, 4 / time, 1 times / day.blank NBP soft capsules 2 / time, 2 times / day. | Beijing Union Medical College Hospital; CSPC-NBP Pharmaceutical Co., Ltd, CSPC-NBP Pharmaceutical Co., Ltd | Acute Cerebral Infarct | | | | |
NCT00331786: Nitric Oxide-Releasing Acetylsalicyclic Acid in Preventing Colorectal Cancer in Patients at High Risk of Colorectal Cancer |
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| Completed | 1 | 240 | US | nitric oxide-releasing acetylsalicylic acid derivative, laboratory biomarker analysis, biopsy | Stony Brook University, National Cancer Institute (NCI) | Colorectal Cancer | | | | |
| Completed | 1 | 11 | NA | aspirin, Acetylsalicyclic Acid, ASA | University of Rochester, University of Miami, Bayer, National Institute of Neurological Disorders and Stroke (NINDS) | Sickle Cell Disease | 04/09 | 11/09 | | |
NCT01072604: Pharmacokinetic Study Comparing Aspirin and Aspirin Granules |
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| Completed | 1 | 30 | US | Acetylsalicylic acid (Aspirin, BAY1019036), Acetylsalicylic acid (Aspirin, BAYE4465) | Bayer | Pharmacokinetics | 08/09 | 08/09 | | |
NCT01409616: To Evaluate Whether Acetyl Salicylic Acid (Aspirin), the Combination of Aspirin and Clopidogrel and Darexaban (YM150) Interact in Their Effects |
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| Completed | 1 | 100 | Europe | darexaban, YM150, darexaban (double dose), Acetyl Salicylic Acid, Aspirin, clopidogrel, Plavix | Astellas Pharma Inc | Pharmacodynamic Interaction, Healthy Subjects | 09/09 | 09/09 | | |
| Completed | 1 | 400 | US | Aspirin | University of Pennsylvania, National Institutes of Health (NIH), Bayer | Aspirin Resistance, Pharmacological Aspirin Non-responsiveness | 10/09 | 10/09 | | |
NCT01081353: Pharmacokinetic Study Comparing Aspirin and Effervescent Aspirin |
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| Completed | 1 | 26 | US | Acetylsalicylic Acid (Aspirin BAY1019036), Alka Seltzer Extra Strength, Aspirin Migraine, Aspirin Aspro | Bayer | Pharmacokinetics | 03/10 | 03/10 | | |
NCT01094483: A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin |
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| Completed | 1 | 40 | US | PN400, ASA, Asprin, Placebo | AstraZeneca, POZEN | Platelet Inhibition | 05/10 | 05/10 | | |
NCT01188304: A Study of Aleglitazar in Combination With Aspirin in Healthy Volunteers |
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| Completed | 1 | 44 | US | aleglitazar, aspirin, placebo | Hoffmann-La Roche | Healthy Volunteer | 10/10 | 10/10 | | |
NCT01199328: Study to Evaluate the Interaction Between Aspirin and Nexium |
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| Completed | 1 | 34 | US | Aspirin, Esomeprazole, Nexium | AstraZeneca | Healthy Volunteers | 11/10 | 11/10 | | |
NCT00727948: The Effect of Aspirin on Angiogenesis Proteins in Women on Tamoxifen Therapy |
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| Completed | 1 | 11 | US | Aspirin | University of Vermont | Breast Cancer, Angiogenesis | 12/10 | 12/12 | | |
NCT01042704: Bendamustine in Combination With Lenalidomide and Dexamethasone in Refractory or Relapsed Multiple Myeloma |
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| Completed | 1 | 29 | US | Bendamustine, Lenalidomide, Dexamethasone, Aspirin, Prophylaxis, Antibiotic, Biweekly Follow Up, Cyclical Follow Up, Restaging, Post-Treatment Follow Up | Robert Redner, MD, Cephalon | Myeloma | 01/11 | 03/15 | | |
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NCT01762787: Phase I Methodology Study to Validate the Cantharidin Blister Model in Healthy Volunteers |
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| Completed | 1 | 40 | Europe | Cantharidin solution, Aspirin, Prednisolone, Placebo to aspirin, Placebo to prednisolone | GlaxoSmithKline | Inflammation | 01/11 | 01/11 | | |
| Completed | 1 | 56 | US | Dimethyl Fumarate (BG00012), Aspirin, BG00012 matching placebo, ASA matching placebo | Biogen | Healthy | 03/11 | 03/11 | | |
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| Completed | 1 | 92 | US | enteric-coated aspirin, acetylsalicylic acid, Chewable aspirin | Vanderbilt University, National Heart, Lung, and Blood Institute (NHLBI) | Coronary Artery Disease | 08/11 | 03/14 | | |
FEATHER, NCT01107925: Comparison of Prasugrel and Clopidogrel in Low Body Weight Versus Higher Body Weight With Coronary Artery Disease |
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| Completed | 1 | 72 | US, Europe | prasugrel, Efient, Effient, LY640315, CS747, clopidogrel | Eli Lilly and Company, Daiichi Sankyo Co., Ltd. | Coronary Artery Disease | 08/11 | 08/11 | | |
NCT01238185: Aspirin Mouthwash in Treating Patients With Oral Leukoplakia |
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| Completed | 1 | 40 | Europe | acetylsalicylic acid, gene expression analysis, protein expression analysis, laboratory biomarker analysis, questionnaire administration, biopsy | Institute of Head and Neck Studies and Education, United Kingdom | Precancerous Condition | 10/11 | 10/11 | | |
GENERATIONS, NCT01107912: Comparison of Prasugrel and Clopidogrel in Very Elderly and Non-Elderly Patients With Stable Coronary Artery Disease |
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| Completed | 1 | 155 | US, Europe | prasugrel, Efient, Effient, LY640315, CS747, clopidogrel | Eli Lilly and Company, Daiichi Sankyo Co., Ltd. | Coronary Artery Disease | 10/11 | 10/11 | | |
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NCT01494402: Study to Assess the Bioequivalence Between D961S and Esomeprazole/Buffered Acetylsalicylic Acid (ASA) in Japanese Healthy Male Subjects |
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| Completed | 1 | 77 | Japan | D961S, Esomeprazole, Nexium® capsule 20 mg, Buffered acetylsalicylic acid, Bufferin Combination Tablet A81 | AstraZeneca | Bioequivalence Study | 03/12 | 03/12 | | |
NCT01448031: A Healthy Female and Male Volunteers Aspirin Study |
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| Completed | 1 | 54 | Europe | Capsule ASA 81mg/esomeprazole 20mg, Acetylsalicylzuur Apotex Cardio | AstraZeneca | Healthy | 04/12 | 04/12 | | |
NCT01708369: Alcohol Inhibits Drug Metabolism by Carboxylesterases |
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| Completed | 1 | 19 | US | Placebo, Tropicana orange juice, Ethanol, Ethanol plus Tropicana orange juice, Oseltamivir, Tamiflu, Aspirin | University of Tennessee | Drug Interactions | 05/12 | 05/12 | | |
NCT00417898: Study of Aspirin and TPA in Acute Ischemic Stroke |
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| Withdrawn | 1 | 0 | RoW | Aspirin | Hadassah Medical Organization | Acute Ischemic Stroke | | 12/12 | | |
NCT02060396 / 2012-001098-94: Study of Biochemical Markers to Determine the Acetylsalicylic Acid Chemopreventive Effect Through Antiplatelet Action |
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| Completed | 1 | 24 | Europe | Acetylsalicylic acid, Adiro 100 | Aragon Institute of Health Sciences | Healthy Volunteers | 06/13 | 12/13 | | |
NCT01847404: Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of ASA (Acetylsalicylic Acid) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fasting Conditions |
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| Completed | 1 | 24 | RoW | Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one, Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two, ASA 100 mg tablet, Aspirin Protect, Pantoprazole 20 mg gastro-resistant tablet, Protium | GlaxoSmithKline, Piramal Clinical Research (Hyderabad, India) | Ulcers, Duodenal and Gastric | 06/13 | 06/13 | | |
NCT01847417: Comparative Bioavailability Study of Two Test Products of Fixed Dose Combination Capsule of Acetylsalicylic Acid (ASA) and Pantoprazole (Each Capsule Contains ASA 100 mg and Pantoprazole 20 mg) Under Fed Conditions |
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| Completed | 1 | 24 | RoW | Test 1= ASA 100 mg and pantoprazole 20 mg capsule formulation one, Test 2= ASA 100 mg and pantoprazole 20 mg capsule formulation two, ASA 100 mg tablet, Pantoprazole 20 mg gastro-resistant tablet | GlaxoSmithKline, Piramal Clinical Research (Hyderabad, India) | Ulcers, Duodenal and Gastric | 07/13 | 07/13 | | |
| Completed | 1 | 18 | Europe | DS-1040b, Aspirin | Daiichi Sankyo, Inc. | Acute Ischemic Stroke | 02/14 | 02/14 | | |
NCT02034292: Safety Study of APD-791 With Aspirin and/or Clopidogrel |
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| Terminated | 1 | 16 | NA | Clopidogrel, Aspirin, APD791, Placebo | IlDong Pharmaceutical Co Ltd, Asan Medical Center | Acute Coronary Syndrome | 03/14 | 03/14 | | |
NCT01744288: Study to See if Platelet Transfusion Stop or Lessen the Effect of the Drug on Platelets |
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| Completed | 1 | 258 | US | Ticagrelor, Clopidogrel, ASA | AstraZeneca | Inhibition on Platelet Aggregation | 04/14 | 04/14 | | |
| Completed | 1 | 48 | US | Aspirin, ASA, Clopidogrel, Plavix | University of Texas Southwestern Medical Center, American Heart Association | Chronic Kidney Disease | 04/14 | 06/14 | | |
ECCLIPSE, NCT02243137: Study of Platelet Function After Administration of Aspirin Versus Lysine Acetylsalicylate |
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| Completed | 1 | 30 | Europe | acetylsalicylic acid, Adiro, prasugrel, Effient, lysine acetylsalicylate, Inyesprin | David Vivas, St Carlos Hospital, Madrid, Spain | Adverse Effect of Antithrombotic Drugs | 06/14 | 06/14 | | |
NCT01710072: Aspirin Attenuates Inflammation in Human Cerebral Aneurysms |
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| Completed | 1 | 11 | US | aspirin | University of Iowa | The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm | 08/14 | 08/14 | | |
| Completed | 1 | 40 | Europe | Ticagrelor + Apixaban + ASA, Ticagrelor + Apixaban | Medical University of Vienna | Atrial Fibrillation, Acute Coronary Syndrome | 10/14 | 02/15 | | |
| Completed | 1 | 10 | US | Microdialysis, Vascepa - Fish Oil, Aspirin, Pioglitazone, Actos | University of Colorado, Denver, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Infertility, Female, Obesity | 12/14 | 12/14 | | |
| Terminated | 1 | 135 | | | Royal Melbourne Hospital, National Health and Medical Research Council | Sepsis | | | | |
| Completed | 1 | 195 | US | Sugar test, Aspirin Challenge | Rush University Medical Center, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcoholic Liver Disease | 03/15 | 03/15 | | |
NCT02394093: To Evaluate the Bioavailability of a Single Oral Dose of the Acetylsalicylic Acid Containing Dry Powder 500 mg in Comparison to the Bioavailability of a Single Oral Dose of Aspirin Tablets and Aspirin Effervescent Tablets in Healthy Adults. |
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| Completed | 1 | 30 | US | Aspirin (Acetylsalicylic acid, BAYe4465) | Bayer | Pharmacology, Clinical | 03/15 | 03/15 | | |
| Completed | 1 | 200 | RoW | Herbal plaster ( styrax, borneol, frankincense, santalum,trichosanthes kirilowii Maxim, allium macrostemon Bunge, leech), Herbal medicine application, acupoint, acupuncture point, Aspirin: 100mg qd; Metoprolol：25mg bid; Ramipril:5mg qd; Atorvastatin:20mg qn., basic treatment | Chengdu University of Traditional Chinese Medicine | Stable Angina Pectoris | 05/15 | 08/15 | | |
| Completed | 1 | 117 | US | Naproxen Sodium (Aleve, BAY117031), Acetylsalicylic Acid (Aspirin, BAYE4465) | Bayer | Hematology | 05/15 | 05/15 | | |
ChiCTR-TRC-13003357: Randomized controlled clinical trial of oral enteric-coated tablet of aspirin for primary liver cancer with portal vein tumor thrombosis surgery prevention of portal vein tumor thrombus recurrence efficacy |
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| Completed | 1 | 180 | | hepatectomy combined with oral enteric-coated tablet of aspirin ;hepatectomy | Eastern Hepatobiliary Surgical Hospital; Eastern Hepatobiliary Surgical Hospital, Eastern Hepatobiliary Surgical Hospital | Liver cancer | | | | |
NCT02370680: Length of Effect of Extended Release Aspirin on Platelets in Patients With Diabetes and Heart Disease |
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| Completed | 1 | 41 | US | Aspirin, Bayer aspirin, Durlaza™ | New Haven Pharmaceuticals, Inc. | Cardiovascular Disease | 07/15 | 07/15 | | |
NCT02341638: Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986141 in Healthy Subjects |
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| Completed | 1 | 148 | US | BMS-986141, Placebo, Aspirin, Itraconazole | Bristol-Myers Squibb | Thrombosis | 09/15 | 09/15 | | |
NCT01047722: In-Vivo Bleeding Volume Test for Platelet-Aspirin Interaction |
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| Unknown status | 1 | 100 | US | Aspirin ingestion followed by doing a Bleeding Volume Test, Gatorade Placebo followed by Bleeding Volume Test. | Klein, Jeffrey A., M.D. | Healthy | 10/15 | 10/15 | | |
NCT01796951: Low Dose Aspirin Inhibition of COX-2 Derived PGE2 in Male Smokers |
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| Completed | 1 | 6 | US | Aspirin 325 mg daily, Celecoxib 200 mg BID | Vanderbilt University | Tobacco Use Disorder, Smoking | 02/16 | 02/16 | | |
NCT03197779: A Short and Long Intravenous Infusion Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-962212 in Healthy Subjects |
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| Completed | 1 | 691 | US | BMS-962212, Aspirin, Placebo | Bristol-Myers Squibb | Thrombosis | 02/16 | 01/17 | | |
NCT02062255: Impact of COX2 on Sera Biomarkers From Obese Subjects |
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| Completed | 1 | 126 | US | Aspirin, Omega 3 FFA | The University of Texas Health Science Center at San Antonio | Breast Cancer Survivors | 04/16 | 04/16 | | |
| Completed | 1 | 50 | US | Aspirin, Indomethacin | Sally E. Wenzel MD | Asthma, Electrophilic Fatty Acids | 09/16 | 06/17 | | |
NCT02268565: Preventing the Inflammatory Response to Experimentally-induced Insomnia Symptoms |
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| Completed | 1 | 8 | US | Aspirin, non-steroidal anti-inflammatory drug, Placebo | Beth Israel Deaconess Medical Center | Insomnia | 10/16 | 12/16 | | |
| Completed | 1 | 135 | US | Aspirin, Ticagrelor | Duke University | Platelet Aggregation Inhibitors, Aspirin, Ticagrelor, RNA | 12/16 | 12/16 | | |
NCT00731302: Aspirin Resistance in Systemic Lupus Erythematosus (SLE) |
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| Completed | 1 | 70 | US | aspirin and meloxicam, generic, not applicable | Vanderbilt University, National Heart, Lung, and Blood Institute (NHLBI) | Systemic Lupus Erythematosus | 04/17 | 04/17 | | |
NCT03051646: Aspirin as a Pre-Treatment for Exercise in Multiple Sclerosis |
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| Completed | 1 | 12 | US | Acetylsalicylic acid at 1st visit, then Placebo at 2nd visit, aspirin, placebo, Placebo at 1st visit, then Acetylsalicylic acid at 2nd visit | Columbia University, National Multiple Sclerosis Society | Fatigue, Overheating | 05/17 | 05/17 | | |
NCT03130153: Topical Analgesic Versus Saline Mouth Rinses in Post Extraction Healing |
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| Completed | 1 | 60 | RoW | Aspirin Powder, Acetyl salicylic acid, Normal saline, 0.9% NaCl, Saline | Aga Khan University | Tooth Extraction Site Healing | 07/17 | 12/17 | | |
NCT03225352: A Study to Assess Disintegration of the New Aspirin Disintegrating Tablets |
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| Completed | 1 | 12 | Europe | 500 mg acetylsalicylic acid (Aspirin, BAYE4465), 1000 mg acetylsalicylic acid (Aspirin, BAYE4465), 400 mg ibuprofen(Nurofen), 400 mg ibuprofen (Dolormin Extra) | Bayer | Moderate Pain | 10/17 | 10/17 | | |
NCT03341390: An Investigational Study to Assess the Effect of BMS-986177 on Aspirin in Healthy Participants |
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| Completed | 1 | 20 | US | Aspirin, Acetylsalicylic Acid, BMS-986177, Placebo | Bristol-Myers Squibb | Healthy Volunteers | 11/17 | 11/17 | | |
NCT01707823: Low-Dose Acetylsalicylic Acid in Treating Patients With Stage I-III Non-Small Cell Lung Cancer |
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| Terminated | 1 | 4 | US | acetylsalicylic acid, ASA, Ecotrin, Empirin, Extren, laboratory biomarker analysis | Vanderbilt-Ingram Cancer Center, National Cancer Institute (NCI) | Adenocarcinoma of the Lung, Recurrent Non-small Cell Lung Cancer, Stage IA Non-small Cell Lung Cancer, Stage IB Non-small Cell Lung Cancer, Stage IIA Non-small Cell Lung Cancer, Stage IIB Non-small Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer | 06/18 | 08/18 | | |
| Completed | 1 | 50 | US | Aspirin, Acetylsalicylic acid (ASA), Placebo | University of Minnesota | Healthy | 06/18 | 08/18 | | |
NCT03456960: A Study to Evaluate the Bioequivalence (BE) and the Food Effect of TAK-438ASA Tablet |
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| Completed | 1 | 276 | Japan | TAK-438ASA, TAK-438, Aspirin | Takeda | Healthy Volunteers | 10/18 | 10/18 | | |
NCT06419283: Prospective Study on Safety and Efficacy of Stenting for Chronic Middle Cerebral Artery Occlusion With Limb Dysfunction |
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| Completed | 1 | 59 | RoW | Middle Cerebral Artery Stent Implantation, standard treatment with aspirin. | Huizhou Municipal Central Hospital | Chronic Middle Cerebral Artery Occlusion, Stenting Treatment, Modified Rankin Scale, National Institutes of Health Stroke Scale | 12/22 | 03/24 | | |
NCT04328883: Pharmacodynamics and Pharmacokinetics of Aspirin Inhalation Powder With Non-Enteric-Coated Chewable Aspirin |
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| Completed | 1 | 19 | US | Aspirin, Bayer Aspirin | Inova Health Care Services | Platelet Aggregation Inhibitors | 10/19 | 10/19 | | |
APPLE, NCT03100123: AntiPhospholipid Syndrome Low-molecular-weight Heparin Pregnancy Loss Evaluation: The Pilot Study |
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| Terminated | 1 | 1 | Canada | Aspirin 81 mg, Acetylsalicylic Acid, Low-molecular-weight heparin, Tinzaparin, Dalteparin, Enoxaparin, LMWH | Ottawa Hospital Research Institute | Antiphospholipid Syndrome in Pregnancy, Pregnancy Loss | 10/19 | 10/19 | | |
NCT03844191: A Randomized Phase 1 Dose-Escalation Study of Subcutaneously(SC) Administered RUC-4 |
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| Completed | 1 | 44 | US | RUC-4 Compound | CeleCor Therapeutics, Precision For Medicine, CirQuest Labs, CRL | Coronary Disease | 11/19 | 12/19 | | |
NCT03900871: Clinical Research on the Effect of Aspirin on the Disease Free Survival Rate of Esophageal Carcinoma |
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| Not yet recruiting | 1 | 600 | RoW | Acetylsalicylic acid | Hebei Medical University Fourth Hospital | Aspirin as an Adjuvant Therapy, to Observe Its Effect on the Disease Free Survival Rate of Patients With Esophageal Squamous Cell Carcinoma | 04/20 | 04/24 | | |
NCT05055752: Randomized, Crossover Bioequivalence Study of PL-ASA Versus Immediate Release Aspirin in Healthy Volunteers. |
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| Completed | 1 | 24 | US | Pharmaceutical-lipid aspirin (PL-ASA), Immediate-release aspirin (IR-ASA) | PLx Pharma | Bioequivalence | 06/20 | 10/20 | | |
NCT02047539: Randomized Controlled Trial of Aspirin vs Placebo in the Treatment of Pre-psychosis |
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| Terminated | 1 | 1 | US | Aspirin, Placebo | Yale University | Clinical High Risk for Psychosis | 03/21 | 03/21 | | |
NCT04792723: Pharmacokinetic and Pharmacodynamic Study of a Novel Sublingual Aspirin Tablet |
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| Not yet recruiting | 1 | 24 | NA | Sublingual aspirin, Oral aspirin | Vita Green Health Products Co. Ltd | Cardiovascular Diseases | 07/21 | 09/21 | | |
ChiCTR2000038524: Persistent Wound Drainage among Total Joint Arthroplasty Patients Receiving Aspirin vs Coumadin |
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| Not yet recruiting | 1 | 100 | | aspirin ;Coumarin | Affiliated Hospital of Xuzhou Medical University; Affiliated Hospital of Xuzhou Medical University, None | Total Joint Arthroplasty | | | | |
| Completed | 1 | 57 | US | Aspirin | University of Utah, University of Colorado, Denver | Aspirin Sensitivity | 10/21 | 10/21 | | |
NCT04588727: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AZD3366 in Healthy Subjects, Japanese and Chinese Subjects |
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| Completed | 1 | 103 | US | AZD3366, Placebo, Ticagrelor, Brilinta, acetylsalicylic acid (ASA), Chewable aspirin | AstraZeneca | Cardiovascular Disease | 01/22 | 01/22 | | |
NCT04083950: Induction of Gut Permeability by an Oral Vaccine |
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| Active, not recruiting | 1 | 10 | US | Vivotif Typhoid Oral Vaccine, Ty21a Typhoid Oral Vaccine, Aspirin (Positive Control), Aspirin Challenge | USDA, Western Human Nutrition Research Center | Intestinal Permeability, Inflammation, Vaccine, Typhoid Fever | 01/22 | 09/24 | | |
| Completed | 1 | 40 | Europe | Low dose irradiation + Nivolumab + Ipilimumab or Cyclophosphamide + Aspirin/Celecoxib | Centre Hospitalier Universitaire Vaudois | Solid Tumor, Adult | 10/23 | 10/23 | | |
NCT05166096: Comparative Pharmacokinetic, Pharmacodynamic, and Safety Study of 1 Dose Level of Aspirin for Injection and Oral Aspirin Tablets in Healthy Adult Human Subjects |
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| Completed | 1 | 24 | US | Rho-11, Intravenous aspirin, aspirin 325mg | Rhoshan Pharmaceuticals Inc | Healthy | 05/22 | 05/22 | | |
NCT05304845: Drug-drug Interactions Between DWP14012 and Aspirin in Healthy Subjects |
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| Completed | 1 | 24 | RoW | DWP14012, Aspirin | Daewoong Pharmaceutical Co. LTD. | Drug Drug Interaction | 05/22 | 05/22 | | |
NCT04535804: Aspirin in the Treatment of Pregnant Women With Adenomyosis on Reducing Preterm Delivery |
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| Not yet recruiting | 1 | 550 | NA | Aspirin/placebo, acetylsalicylic acid | Shanghai First Maternity and Infant Hospital | Adenomyosis of Uterus | 09/22 | 09/22 | | |
ChiCTR2000037511: The effect of intravenous immunoglobulin on pregnancy outcomes of recurrent spontaneous abortion combined with antiphospholipid syndrome：a multi-center clinical trial |
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| Not yet recruiting | 1 | 360 | | aspirin+low molecular weight heparin+prednisone ;aspirin+low molecular weight heparin+prednisone+intravenous immunoglobulin | Shanghai First Maternity and Infant Hospital; Shanghai First Maternity and Infant Hospital, Hospital development center | recurrent spontaneous abortion | | | | |
NCT05237843: Hydroxychloroquine in Unexplained Recurrent Pregnancy Loss |
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| Not yet recruiting | 1 | 70 | NA | Hydroxychloroquine, placebo - Aspirin (LDA) - Clexan (LMWH) | Ain Shams University | Recurrent Pregnancy Loss | 11/22 | 01/23 | | |
| Completed | 1 | 268 | US | Aspirin 500 MG, actelysalicylic acid, Placebo | Ohio State University | Healthy Adults | 04/22 | 04/22 | | |
IMPACT, NCT03378297: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC |
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| Completed | 1 | 26 | Europe | Metformin, Acetylsalicylic acid, Olaparib, Letrozole | Haukeland University Hospital | Ovarian Cancer | 01/23 | 01/23 | | |
NCT05625334: Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults. |
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| Completed | 1 | 86 | US | ASA, non-enteric-coated chewable aspirin | Vectura, Inc., Syneos Health | Healthy Volunteers | 03/23 | 03/23 | | |
| Completed | 1 | 157 | US | Wintergreen Throat Spray and Aspirin Tablet, Group B, Aspirin Throat Spray and Placebo Tablet, Group C, Wintergreen Throat Spray and Placebo Tablet, Group D, Placebo Throat Spray and Placebo Tablet, Group A | Applied Biological Laboratories Inc, Econometrica, Inc. | Common Cold, Pharyngitis, Fever, Congestion, Rhinorrhea, Cough, Sore-throat, Sore Throats Viral, Malaise, Headache, Runny Nose, Sneezing | 04/23 | 06/23 | | |
NCT05308030: Outcomes of Rivaroxaban and Aspirin in PAD After Endovascular Revascularization |
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| Not yet recruiting | 1 | 100 | NA | Rivaroxaban and Aspirin | Assiut University | Peripheral Arterial Disease | 05/23 | 07/23 | | |
NCT03771651: Short Term Aspirin on the Biologic and Immunologic Changes of the Fallopian Tube |
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| Active, not recruiting | 1 | 18 | US | Aspirin 81 mg | University of Oklahoma | Fallopian Tube Cancer, Fallopian Tube Infection | 05/22 | 06/25 | | |
