| Exviera (dasabuvir) / AbbVie |
CHESS, ACTRN12615001167550: - Curing Hepatitis C: Effect on the Endothelium and cardiovaScular riSk - a pilot single arm trial, assessing the effect of hepatitis C virus (HCV) treatment with 12 weeks of paritaprevir/ritonavir/ombitasvir, dasabuvir +/- ribavirin on endothelial function. |
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| Completed | 4 | 16 | | | John Hunter Hospital, Abbvie Sciences | Hepatitis C virus infection, Endothelial function | | | | |
NCT02734173: Pilot HCV Direct Acting Antiviral Therapy and Metabolism |
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| Completed | 4 | 24 | Canada | ABT450r-ABT267-ABT333 +/- Ribavirin, ombitasvir/paritaprevir/ritonavir, dasabuvir, ribavirin | Ottawa Hospital Research Institute, AbbVie | Hepatitis C | 02/17 | 05/17 | | |
2016-003607-59: An Open-Label Study to Evaluate Long-Term Results With Ombitasvir-Paritaprevir-Ritonavir and Dasabuvir With or Without Ribavirin (RBV) on ovarian function in fertile women With Genotype 1 and 4 Chronic Hepatitis C Virus (HCV) Infection. Studio in aperto per valutare i risultati a lungo termine con Ombitasvir-paritaprevir-Ritonavir e Dasabuvir, con o senza ribavirina (RBV) sulla funzione ovarica delle donne in et¿ fertile con epatite cronica HCV-positiva, genotipo 1 e 4 . |
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| Terminated | 4 | 50 | Europe | VIEKIRAX, EXVIERA, 043841, Film-coated tablet, VIEKIRAX - 12,5MG/75MG/50MG COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PVC/PE/PCTFE/ALU) - 56 COMPRESSE (CONFEZIONE MULTIPLA), EXVIERA - 250 MG COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER (PVC/PE/PCTFE/ALU) - 56 COMPRESSE (CONFEZIONE MULTIPLA) | DIPARTIMENTO AD ATTIVITà INTEGRATA CHIRURGICO, MEDICO, ODONTOIATRICO E DI SCIENZE MORFOLOGICHE, ABBVIE SRL | Genotype 1 and 4 Chronic Hepatitis C Virus (HCV) Infection Epatite cronica HCV-positiva, genotipo 1 e 4, Hepatitis C EPATITE C, Diseases [C] - Virus Diseases [C02] | | | | |
NCT02461745: Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO |
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| Completed | 4 | 200 | US | ombitasvir, paritaprevir/r, dasabuvir + ribavirin, VIEKIRA PAK + RBV, ombitasvir, paritaprevir/r, dasabuvir, VIEKIRA PAK | Kaiser Permanente, AbbVie | Hepatitis C, Chronic | 05/17 | 05/17 | | |
| Completed | 4 | 87 | RoW | "3D" regimen, Viekira pack, "3D" regimen with ribavirin, Viekira pack with ribavirin | Kirby Institute | Hepatitis C, Chronic | 08/17 | 03/19 | | |
| Completed | 4 | 100 | NA | paritaprevir/ritonavir/ombitasvir + dasabuvir +/- ribavirin | American Research Corporation, AbbVie | Chronic Hepatitis C | 09/17 | 09/17 | | |
NCT03050905: Proof of Concept Study To Evaluate the Efficacy and Justification Of OBV/PTV/r and DSV In Adults With Chronic Hepatitis C Virus Genotype 2K/1B |
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| Completed | 4 | 7 | RoW | VEKIRAX, Ombitasvir+Paritaprevir+Ritonavir, EXVIERA, Dasabuvir | HaEmek Medical Center, Israel, AbbVie | HCV Coinfection | 11/17 | 11/18 | | |
NCT02950870: Efficacy Study to Evaluate the Effect of New Antiviral Drugs on HCV Infection. |
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| Unknown status | 4 | 75 | Europe | Ombitasvir-Paritaprevir-Ritonavir, Viekirax, Dasabuvir, Exvieria, Ribavirin, RBV | University of Modena and Reggio Emilia | Chronic Hepatitis, C Virus | 12/17 | 12/19 | | |
NCT03003338: MHH-HCV-NPM-Neuropsychiatric Manifestations of HCV-infection During and After Treatment With OBV/PTV/r and DSV |
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| Terminated | 4 | 5 | Europe | OBV/PTV/r and DSV, Viekirax and Exviera, Placebo to match OBV/PTV/r and DSV | Hannover Medical School, AbbVie | Hepatitis C, Chronic | 10/18 | 10/18 | | |
| Completed | 4 | 46 | RoW | PTV/r/OBV/DSV, Viekirax/Exviera | National Taiwan University Hospital, AbbVie | Hepatitis Viruses | 10/18 | 12/18 | | |
| Completed | 4 | 1275 | US | SOF/LDV (sofosbuvir/ledipasvir), Harvoni® (sofosbuvir/ledipasvir), PrOD (ombitasvir/paritaprevir/ritonavir with dasabuvir) (Phase 1 only), Viekira Pak/Viekira, EBR/GZR (elbasvir/grazoprevir), Zepatier, Ribavirin, RBV | University of Florida, Patient-Centered Outcomes Research Institute, Merck Sharp & Dohme LLC, AbbVie | Chronic Hepatitis C | 06/19 | 09/20 | | |
NCT02460133: Understanding HCV Reinfection Rates in an Incarcerated Population After Cure With Interferon Free HCV Treatment |
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| Active, not recruiting | 4 | 44 | NA | Paritaprevir, Ritonavir, Dasabuvir, Ombitasvir, Ribavirin | Nova Scotia Health Authority, Provincial Correction Centre (PEI) | Hepatitis C Virus | 10/25 | 10/25 | | |
