| sertraline / Generic mfg. |
ACTRN12624000475549: A randomised double-blinded interventional trial of Estradiol and Zoloft to treat Menopausal Depression |
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| Not yet recruiting | 3 | 120 | | | Monash University, Monash University | Menopausal depression, Depression, Menopause | | | | |
NCT00000384: Treatment of Obsessive-Compulsive Disorder (OCD) in Children |
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| Completed | 3 | | US | Cognitive Behavior Therapy, Educational Support, Sertraline | University of Pennsylvania, National Institute of Mental Health (NIMH) | Obsessive-Compulsive Disorder | | 04/02 | | |
| Completed | 3 | 20 | US | sertraline, venlafaxine XR | Vanderbilt University, Pfizer | Major Depressive Disorder | | 04/03 | | |
NCT00179257: The Effectiveness of Sertraline in Patients Who Have Had Inadequate Response to Escitalopram |
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| Completed | 3 | 20 | US | sertraline (Zoloft) | Vanderbilt University, Pfizer | Major Depressive Disorder | | 03/05 | | |
NCT02122393: A Randomised Trial of Sertraline, Cognitive Behaviour Therapy & Combined Therapy for Postnatal Depression |
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| Completed | 3 | 45 | RoW | Sertraline, Cognitive Behavioural Therapy | University of Melbourne, Pfizer | Depression, Anxiety | 04/05 | 04/05 | | |
NCT00066859: Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression |
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| Completed | 3 | 2 | US | Zoloft 50 mg, Sertraline, Zoloft, St. John's Wort 600 mg, Hypericum perforatum | Wake Forest University Health Sciences, National Cancer Institute (NCI) | Depression, Unspecified Adult Solid Tumor, Protocol Specific | 04/05 | 11/05 | | |
NCT00078767: Pharmacologic Treatment of PTSD in Sexually Abused Children |
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| Completed | 3 | 24 | US | Trauma-Focused Cognitive Behavioral Therapy, Sertraline Pill, Placebo Oral Tablet | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), National Institute of Mental Health (NIMH) | Stress Disorders, Post-Traumatic | 03/06 | 03/06 | | |
ACTRN12605000381684: Antidepressants, well-being and survival in advanced cancer. The ZEST Trial: A double-blind, placebo-controlled trial of Zoloft's Effects on Symptoms and survival Time in Advanced Cancer |
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| Terminated | 3 | 440 | | | CTC, Cancer Council, Pfizer, CTC | People with advanced cancer in whom there is doubt about the benefits of treatment with antidepressants. | | | | |
NCT00232167: Study Of Indiplon/Placebo With Sertraline In Insomnia Co-Existing With Depression |
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| Terminated | 3 | 380 | US | Indiplon, Sertraline | Neurocrine Biosciences | Insomnia, Depression | | 04/06 | | |
NCT00276900: Sertraline for the Prevention of Recurrent Postpartum Depression |
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| Completed | 3 | 300 | US | Sertraline | University of Pittsburgh, National Institute of Mental Health (NIMH) | Depression | 08/06 | 08/06 | | |
NCT00655174: Fluvoxamine and Sertraline in Childhood Autism - Does SSRI Therapy Improve Behaviour and/or Mood? |
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| Completed | 3 | 108 | Canada | fluvoxamine, sertraline, Placebo | The Hospital for Sick Children | Autism | 09/06 | 01/07 | | |
| Completed | 3 | 494 | Canada, Europe, RoW | Quetiapine, Amitriptyline, Bupropion, Citalopram, Duloxetine, Escitalopram, Fluoxetine, Paroxetine, Sertraline, Venlafaxine | AstraZeneca | Major Depressive Disorder | | 04/07 | | |
NCT00331305: Exercise Training Versus Drug Therapy for Treating Depression in Older Adults |
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| Completed | 3 | 457 | US | Supervised Exercise, Home-Based Exercise, Sertraline (Zoloft), Placebo Pill | Duke University, National Institute of Mental Health (NIMH) | Depression | | 05/07 | | |
NCT00026637: Depression and Health Outcomes in Refractory Epilepsy |
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| Completed | 3 | 140 | US | sertraline, cognitive behavior therapy, CBT | Columbia University, National Institute of Neurological Disorders and Stroke (NINDS) | Depression, Epilepsy | 06/07 | 06/08 | | |
NCT00491478: Repetitive Behavior Disorders in People With Severe Mental Retardation |
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| Unknown status | 3 | | US | sertraline | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Mental Retardation, Stereotyped Behavior, Self-Injurious Behavior, Compulsive Behavior | | | | |
NCT00158990: Triiodothyronine (T3) Supplementation in the Treatment of Bipolar and Unipolar Depression. |
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| Completed | 3 | 220 | US, RoW | triiodothyronine, sertraline | Hadassah Medical Organization, Stanley Medical Research Institute | Major Depression, Bipolar Disorder, Unipolar Depression | | 07/07 | | |
NCT00150306 / 2014-004162-17: A Ten-Week Study Evaluating The Effectiveness And Safety Of Zoloft In Children And Adolescents With A Diagnosis Of PTSD |
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| Terminated | 3 | 160 | US | Zoloft (Sertraline) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Stress Disorders, Post-Traumatic | | 07/07 | | |
NCT00174590: Treatment of Major Depressive Disorder With Psychotic Features. |
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| Terminated | 3 | 30 | US | risperidone | Rush University Medical Center, Janssen, LP | Major Depression With Psychotic Features | | 08/07 | | |
| Completed | 3 | 488 | US | Sertraline (SRT), Zoloft, Cognitive Behavioral Therapy (CBT), Placebo | Johns Hopkins University, National Institute of Mental Health (NIMH) | Anxiety Disorders, Social Phobia, Generalized Anxiety Disorder | 10/07 | 03/08 | | |
| Completed | 3 | 259 | US, Canada | Olanzapine, Zyprexa, Sertraline, Zoloft, placebo | Weill Medical College of Cornell University, National Institute of Mental Health (NIMH) | Major Depressive Disorder With Psychotic Features | 06/08 | 06/08 | | |
NCT00043550: Treatments for Depression: Drug Versus Psychotherapy |
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| Completed | 3 | 156 | US | Supportive Expressive Therapy, Sertraline, Zoloft, Pill Placebo, Venlafaxine, Effexor | University of Pennsylvania, National Institute of Mental Health (NIMH) | Depression | 06/09 | 06/09 | | |
NCT00116857: Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors |
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| Completed | 3 | 122 | US | Sertraline/omega-3, Sertraline/Corn Oil | Washington University School of Medicine, National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases, Depression, Heart Diseases, Myocardial Infarction, Angina, Unstable | 06/09 | 11/09 | | |
NCT00074815: Treatment of Obsessive Compulsive Disorder in Children |
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| Completed | 3 | 124 | US | Serotonin reuptake inhibitors management, Drug Name with Minimum-Maximum Dosage, Citalopram (Celexa)10-60;, Escitalopram (Lexapro)5-30;, Fluoxetine (Prozac) 10-60;, Fluvoxamine (Luvox)25-300;, Paroxetine (Paxil)10-50;, Paroxetine-CR (Paxil)10-50;, Clomipramine (Anafranil)25-200;, Sertraline (Zoloft) 25-200;, Venlafaxine (Effexor)25-225;, Venlafaxine XR (Effexor)37.5-225;, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist | Duke University, National Institute of Mental Health (NIMH) | Obsessive-Compulsive Disorder | 11/09 | 11/09 | | |
NCT01015976: A Preliminary Comparison of the Blood Levels of Medications in Obese Subjects Compared to Post-Gastric Bypass Subjects |
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| Completed | 3 | 10 | US | bariatric surgery, control | Neuropsychiatric Research Institute, Fargo, North Dakota, University of North Dakota | Obesity | 04/10 | 04/10 | | |
| Completed | 3 | 27 | Europe | Extended release quetiapine (quetiapine XR), SEROQUEL XR®, Sertraline, Zoloft, adequate mood stabilizer | AstraZeneca | Bipolar Disorder, Bipolar Depression | 02/11 | 02/11 | | |
| Completed | 3 | 101 | US | Supervised Aerobic Exercise, Sertraline, Placebo Pill. | Duke University, Pfizer | Depression, Heart Diseases | 07/11 | 12/11 | | |
NCT00127673: Comparison of Two Treatments for Post-Traumatic Stress Disorder |
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| Completed | 3 | 200 | US | Sertraline, Zoloft, Cognitive behavioral therapy (CBT), Prolonged exposure (PE) | Case Western Reserve University, National Institute of Mental Health (NIMH) | Post-Traumatic Stress Disorder | 08/11 | 08/11 | | |
NCT00276965: Bipolar II Depression: Lithium, SSRI, or the Combination |
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| Completed | 3 | 139 | US | Sertraline, Zoloft, Lithium carbonate, Eskalith, Lithobid | Lindner Center of HOPE, National Institute of Mental Health (NIMH), University of California, Los Angeles, Stanford University | Bipolar Disorder, Depression | 03/12 | 07/12 | | |
NCT01098318: Rhodiola Rosea Therapy of Major Depressive Disorder |
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| Completed | 3 | 58 | US | Herbal extract, Golden root, Sertraline, Zoloft, Lactose monohydrate, Milk powder | University of Pennsylvania, National Center for Complementary and Integrative Health (NCCIH) | Depression | 07/13 | 07/13 | | |
| Completed | 3 | 203 | RoW | sertraline, Zoloff, citalopram, Cipramil, venlafaxine, Effexor, reboxetine, Edronax, control, cognitive behavioral therapy | Guiyang Medical University | Bone Mineral Density Quantitative Trait Locus 7 | 04/14 | 04/14 | | |
NCT01214382: Pharmacokinetic Properties of Sertraline Before and After Gastric Bypass Surgery |
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| Completed | 3 | 31 | US | Sertraline, Zoloft | North Dakota State University, National Institutes of Health (NIH) | Roux en Y Gastric Bypass Surgery | 08/14 | 08/14 | | |
NCT01987960 / 2012-004982-41: Brexpiprazole as an Adjunctive Treatment to Paroxetine or Sertraline in Adult Patients Suffering From Post-traumatic Stress Disorder (PTSD) |
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| Terminated | 3 | 417 | US, Europe, RoW | Placebo, Brexpiprazole | H. Lundbeck A/S, Otsuka Pharmaceutical Co., Ltd. | Post-traumatic Stress Disorder, PTSD | 10/15 | 10/15 | | |
2004-004009-10: Efficacy of agomelatine (25 mg/day with potential adjustment to 50 mg) given orally on rest/activity circadian rhythms in outpatients with Major Depressive Disorder. A randomized, double-blind international study with parallel groups versus sertraline (50 mg/day with potential adjustment to 100 mg). Six-week treatment plus optional continuation for 18 weeks. |
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| | 3 | 100 | Europe | ZOLOFT, S20098-F56, S20098-F57, GLADEM, GLADEM | Institut de Recherches Internationales Servier, Laboratorios Servier S.L. (For Spain only), INSTITUT DE RECHERCHES INTERNATIONALES SERVIER | Major Depressive Disorder | | 03/07 | | |
| Completed | 3 | 150 | | | Flinders University, Commonwealth Department of Health and Ageing | Intractable dyspnoea | | | | |
| Completed | 3 | 201 | US | Sertraline, placebo | VA Office of Research and Development, University of Texas Southwestern Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Chronic Kidney Disease, Depression | 11/16 | 11/17 | | |
NCT01600456: Optimizing Posttraumatic Stress Disorder Treatment: Prolonged Exposure (PE) Versus PE Plus Sertraline |
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| Completed | 3 | 150 | US | Prolonged exposure (PE), PE plus Sertraline, Zoloft | Case Western Reserve University, University of Washington, National Institute of Mental Health (NIMH) | Posttraumatic Stress Disorder | 01/17 | 01/17 | | |
2013-004881-33: Multicentre trial in to investigate the usage of antidepressant and antipsychotics (with / without approval) in patients at the age of children and adolescents Groß an gelegte, einfache offene klinische Studie mit mehreren teilnehmenden Prüfzentren zur Anwendung von Antidepressiva und Neuroleptika (mit /ohne Zulassung) |
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| Ongoing | 3 | 1000 | Europe | Tablet, Abilify, Zyprexa, Leponex, Seroquel, Risperdal, Zeldox, Melneurin, Dipiperon, Saroten, Cipramil, Anafranil, Aponal, Cymbalta, Cipralex, Fluctin, Fevarin, Tofranil, Ludiomil, Remergil, Nortrilen, Paroxat, Zoloft, Stangyl, Trevilor | Universitätsklinikum Würzburg, Kompetenznetz TDM-KJP e.V., BfArM | therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, therapeutic use in clinical practise Therapeutische Anwendung im klinischen Alltag, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Completed | 3 | 2944 | Canada, US, Europe, RoW | OPC-34712, Escitalopram, Lexapro, Fluoxetine, Prozac, Paroxetine CR, Paxil CR, Sertraline, Zoloft, Duloxetine, Cymbalta, Venlafaxine XR, Effexor XR | Otsuka Pharmaceutical Development & Commercialization, Inc. | Depressive Disorder, Depression, Depressive Disorder, Major, Mood Disorders, Mental Disorders | 04/17 | 05/17 | | |
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TRANSFORM-2, NCT02418585 / 2014-004585-22: A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression |
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| Completed | 3 | 236 | Europe, US, RoW | Esketamine, Placebo, Duloxetine (Oral Antidepressant), Escitalopram (Oral antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant) | Janssen Research & Development, LLC | Treatment-resistant Depression | 06/17 | 11/17 | | |
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NCT02374567: Pharmacovigilance in Gerontopsychiatric Patients |
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| Terminated | 3 | 407 | Europe | Phenobarbital, Phenytoin, Carbamazepine, Oxcarbazepine, Valproic Acid, Lamotrigine, Topiramate, Gabapentin, Levetiracetam, Pregabalin, Lacosamide, Clonazepam, Biperiden, Levomepromazine, Fluphenazine, Perphenazine, Perazine, Thioridazine, Haloperidol, Melperone, Pipamperone, Bromperidol, Benperidol, Sertindole, Ziprasidone, Flupentixol, Chlorprothixene, Zuclopenthixol, Fluspirilene, Pimozide, Clozapine, Olanzapine, Quetiapine, Sulpiride, Tiapride, Amisulpride, Prothipendyl, Risperidone, Aripiprazole, Paliperidone, Diazepam, Oxazepam, Lorazepam, Bromazepam, Clobazam, Alprazolam, Hydroxyzine, Buspirone, Chloral Hydrate, Flurazepam, Nitrazepam, Triazolam, Lormetazepam, Temazepam, Midazolam, Brotizolam, Zopiclone, Zolpidem, Zaleplon, Melatonin, Clomethiazole, Diphenhydramine, Promethazine, Imipramine, Clomipramine, Opipramol, Trimipramine, Amitriptyline, Nortriptyline, Doxepin, Maprotiline, Amitriptyline oxide, Fluoxetine, Citalopram, Paroxetine, Sertraline, Fluvoxamine, Escitalopram, Tranylcypromine, Moclobemide, Mianserin, Trazodone, Mirtazapine, Bupropion, Venlafaxine, Reboxetine, Duloxetine, Agomelatine, Pyritinol, Piracetam, Donepezil, Rivastigmine, Galantamine, Memantine, Nicergoline, Acamprosate, Lithium | Hannover Medical School | Dementia, Depression, Schizophrenia, Psychosomatic Disorders, Anxiety Disorders | 06/17 | 06/17 | | |
TRANSFORM-3, NCT02422186 / 2014-004588-19: A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression |
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| Completed | 3 | 139 | Europe, US, RoW | Esketamine, Placebo, Duloxetine (Oral Antidepressant), Escitalopram (Oral Antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (New Antidepressant) | Janssen Research & Development, LLC | Depressive Disorder, Treatment-Resistant | 08/17 | 08/17 | | |
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| Completed | 3 | 460 | RoW | Sertraline, Zoloft, Lustral | University of Minnesota, Infectious Disease Institute, Kampala, Uganda, National Institute of Neurological Disorders and Stroke (NINDS), Mbarara University of Science and Technology, Medical Research Council, Wellcome Trust, Makerere University | Cryptococcal Meningitis, Fungal Meningitis | 09/17 | 09/17 | | |
| Completed | 3 | 802 | Europe, US, RoW | Esketamine (Intranasal Spray), Duloxetine (Oral Antidepressant), Escitalopram (Oral Antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant) | Janssen Research & Development, LLC | Treatment-resistant Depression | 10/17 | 10/17 | | |
ASCEND, NCT02358343: A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {} |
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| Completed | 3 | 184 | US | Engagement Interview, Cognitive Behavioral Therapy, CBT, Antidepressant Drug Therapy, Sertraline, "Zoloft" | University of Washington, University of Texas, University of New Mexico, Patient-Centered Outcomes Research Institute | Depression, End Stage Renal Disease | 11/17 | 12/17 | | |
| Completed | 3 | 719 | Europe, Canada, US, RoW | Esketamine, Placebo, Duloxetine (Oral Antidepressant), Escitalopram (Oral antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant) | Janssen Research & Development, LLC | Depressive Disorder, Treatment-Resistant | 02/18 | 02/18 | | |
TRANSFORM-1, NCT02417064 / 2014-004584-20: A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression |
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| Completed | 3 | 346 | Europe, Canada, US, RoW | Esketamine, Placebo, Duloxetine (Oral Antidepressant), Escitalopram (Oral antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant) | Janssen Research & Development, LLC | Treatment-resistant Depression | 02/18 | 02/18 | | |
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| Terminated | 3 | 22 | RoW | Sertraline, Zoloft, Lustral, Sertraline hydrochloride, Placebo Oral Tablet, Placebo, Fluconazole, Fluconazole 200mg tab | University of Minnesota, Infectious Diseases Institute, Uganda, National Institute of Allergy and Infectious Diseases (NIAID), Mbarara University of Science and Technology | Cryptococcosis, Cryptococcal Infections, AIDS-Related Opportunistic Infections | 03/18 | 03/18 | | |
2020-002787-32: Antidepressant for the prevention of DEPression following first episode Psychosis trial |
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| Not yet recruiting | 3 | 508 | Europe | Sertraline, Film-coated tablet | University of Birmingham, National Institute for Health Research | Patients with First Episode Psychosis., Patients who are experience symptoms of psychosis for the first time., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT03434041: A Study to Evaluate the Efficacy, Pharmacokinetics, Safety and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression |
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| Completed | 3 | 252 | US, RoW | Esketamine 56 mg, Esketamine 84 mg, Placebo, Duloxetine (Oral Antidepressant), Escitalopram (Oral Antidepressant), Sertraline (Oral Antidepressant), Venlafaxine Extended Release (XR) (Oral Antidepressant) | Janssen Research & Development, LLC | Depressive Disorder, Treatment-Resistant | 04/21 | 04/21 | | |
NCT03852160: A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression |
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| Withdrawn | 3 | 0 | NA | Esketamine 28 mg, JNJ-54135419, Esketamine 56 mg, Esketamine 84 mg, Placebo, Escitalopram, Sertraline, Duloxetine, Mirtazapine, Agomelatine, Bupropion, Trazodone Prolonged Release | Janssen-Cilag International NV | Depressive Disorder, Treatment-Resistant | 07/21 | 07/21 | | |
NCT04476030: A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder |
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| Completed | 3 | 440 | US | SAGE-217, Matching Placebo, Sertraline, Escitalopram, Citalopram, Duloxetine, Desvenlafaxine | Biogen | Depressive Disorder, Major | 10/21 | 12/21 | | |
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NCT03538691 / 2018-000601-22: A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder |
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| Completed | 3 | 1149 | US | Brexpiprazole, OPC-34712, Rexulti, Antidepressant therapy | Otsuka Pharmaceutical Development & Commercialization, Inc. | Major Depressive Disorder | 07/22 | 07/22 | | |
NCT05950061: Sertraline Versus Escitalopram in South Asian Participants With Moderate to Severe Major Depressive Disorder |
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| Completed | 3 | 744 | RoW | Sertraline, Sertraline pill, Escitalopram, Escitalopram pill | KRL Hospital, Islamabad, Khyber Medical College, Peshawar, Quaid-e-Azam Medical College, Dow University of Health Sciences | Major Depressive Disorder | 10/22 | 02/23 | | |
NCT04124614: Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD |
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| Completed | 3 | 450 | US | Brexpiprazole, Rexulti, Sertraline, Zoloft, Placebo | Otsuka Pharmaceutical Development & Commercialization, Inc. | Post Traumatic Stress Disorder | 07/23 | 08/23 | | |
NCT04174170: Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder |
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| Completed | 3 | 591 | US | Brexpiprazole, Rexulti, Sertraline, Zoloft, Placebo | Otsuka Pharmaceutical Development & Commercialization, Inc. | Post Traumatic Stress Disorder | 07/23 | 08/23 | | |
NCT06025474: Comparison of Vortioxetine Versus Other Antidepressants With Pregabalin Augmentation in Burning Mouth Syndrome |
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| Recruiting | 3 | 203 | Europe | Vortioxetine 20Mg Tab, Brintellix, Paroxetine 20 Mg Oral Tablet, Sertraline 50 MG, Citalopram 20mg, Escitalopram 10mg, Duloxetine 60 MG, Pregabalin 75mg | Federico II University | Burning Mouth Syndrome | 10/23 | 07/24 | | |
INTENSIFY BD, NCT05973786: The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. |
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| Recruiting | 3 | 418 | Europe | Escitalopram, ATC code: N06AB10, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04 | Dr. Inge Winter, Universität Münster | Bipolar Depression | 06/26 | 06/26 | | |
INTENSIFY, NCT05603104: Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure |
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| Not yet recruiting | 3 | 1254 | RoW | Clozapine, ATC code: N05AH02, Esketamine Nasal Product, ATC code: N06AB10, Escitalopram, Sertraline, ATC code: N06AB06, Venlafaxine, ATC code: N06AX16, Lithium, ATC code: N05AN01, Valproate acid, ATC code: N03AG01, Quetiapine, ATC code: N05AH04, Second-line Antidepressants, Second-line Antipsychotics, Ketamine Hydrochloride, N01AX03, Esketamine hydrochloride, N015X14 | Dr. Inge Winter, Universität Münster | Schizophrenia and Related Disorders, Major Depressive Disorder, Bipolar Depression | 06/26 | 06/26 | | |
NCT00340379: Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression |
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| Completed | 2/3 | 72 | US, RoW | Ziprasidone, Geodon, Sertraline, Zoloft, Haloperidol, Haldol | Duke University, Pfizer, National Institute of Mental Health and Neuro Sciences, India | Affective Disorders | 08/05 | 08/05 | | |
| Completed | 2/3 | 80 | US | sertraline and risperidone | Duke University, Janssen Pharmaceuticals | Post-Traumatic Stress Disorder | | 07/06 | | |
NCT00080158: Treatment of Adolescent Suicide Attempters (TASA) |
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| Completed | 2/3 | 120 | US | fluoxetine, sertraline, citalopram, escitalopram, bupropion, mirtazapine, venlafaxine, lithium, Cognitive Behavioral Therapy | New York State Psychiatric Institute, National Institute of Mental Health (NIMH) | Depression, Suicide, Attempted | | 06/07 | | |
NCT00118417: Therapies for Treatment-Resistant Panic Disorder Symptoms |
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| Completed | 2/3 | 46 | US | Clonazepam, Sertraline, Cognitive behavioral therapy | Massachusetts General Hospital, National Institute of Mental Health (NIMH) | Panic Disorder | 10/07 | 10/07 | | |
NCT00299611: Augmentation Study of Levetiracetam in Obsessive Compulsive Disorder |
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| Terminated | 2/3 | 12 | US | Sertraline, Zoloft, Levetiracetam, Keppra, Placebo | Duke University, UCB Pharma | Obsessive-Compulsive Disorder | 12/07 | 04/08 | | |
| Completed | 2/3 | 469 | US | Sertraline, Zoloft, Placebo, Inactive pill | Duke University, National Institute of Mental Health (NIMH) | Heart Failure, Congestive, Chronic Heart Failure, Depression | 03/08 | 09/08 | | |
| Completed | 2/3 | 131 | US | Sertraline (Zoloft), Placebo | Johns Hopkins University, National Institute of Mental Health (NIMH) | Alzheimer's Disease, Depression | 07/08 | 07/09 | | |
| Completed | 2/3 | 120 | RoW | transcranial direct current stimulation, Sertraline, double placebo | University of Sao Paulo, Fundação de Amparo à Pesquisa do Estado de São Paulo | Depressive Disorder, Major | 12/11 | 12/11 | | |
NCT00704379: Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury |
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| Completed | 2/3 | 94 | US | Placebo, Sertraline, Zoloft | Baylor College of Medicine, National Institute of Neurological Disorders and Stroke (NINDS) | Traumatic Brain Injury | 04/14 | 04/14 | | |
NCT02565316: Efficacy of Nepeta Menthoides Extract on Anxiety of Patients With Depression: a Double-blind Randomized Controlled Clinical Trial |
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| Completed | 2/3 | 70 | RoW | Nepeta menthoides Boiss & Bohse freeze dried extract, Sertraline | Shiraz University of Medical Sciences | Depression, Anxiety | 03/15 | 03/15 | | |
| Recruiting | 2/3 | 330 | US | Antidepressant, AD: aripiprazole, bupropion, duloxetine, escitalopram, mirtazapine, sertraline, venlafaxine, Enhanced Fear Avoidance Rehabilitation, EFAR | Ajay Wasan, MD, Msc, National Institutes of Health (NIH), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Brigham and Women's Hospital, Mayo Clinic | Chronic Low Back Pain, Negative Affectivity | 12/25 | 04/26 | | |
