rosuvastatin / Generic mfg. 
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43 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
rosuvastatin / Generic mfg.
2009-011291-29: RACE 3 study: Intensive vs. usual rhythm control for atrial fibrillation.

Ongoing
4
250
Europe
eplerenone, Spironolactone, atorvastatin, Fluvastatin, Pravastatin, rosuvastatin, Simvastatin, eplerenone, spironolactone, atorvastatin, Fluvastatin, Pravastatin, rosuvastatin, Simvastatin, eplerenone, spironolactone, atorvastatin, Fluvastatin, Pravastatin, rosuvastatin, Simvastatin
Interuniversity Cardiology Institute of the Netherlands (ICIN), Interuniversity Cardiology Institute Netherlands, The Interuniversity Cardiology Institute of the Netherlands (ICIN), Netherlands Heart Foundation (NHS B 2008 035), Working group on Cardiovascular Research, the Netherlands, Sanofi Aventis, Boehringer Ingelheim, Medtronic, Biotronik, St Jude Medical, Boston Scientific, AstraZenenca, Interuniversity Cardiology Institute Netherlands, Working group on Cardiovascular Research, Astra Zeneca, Bayer
atrial fibrillation
 
 
2016-003457-15: Delaying progression of arterial disease

Ongoing
4
350
RoW
Rosuvastatin Krka, Tablet, Rosuvastatin Krka
Icelandic Heart Association, Icelandic Heart Association
Atherosclerosis, Subclinical atherosclerosis of the carotid arteries, Diseases [C] - Cardiovascular Diseases [C14]
 
 
2018-003837-13: Statin effect on atheroma calcification

Not yet recruiting
4
44
Europe
Rosuvastatin, Film-coated tablet, Crestor
Centro Hospitalar e Universitário de Coimbra, E.P.E., Astrazeneca-Produtos Farmacêuticos, Lda
Atherosclerosis, namely in the aorta, carotid and coronary arteries, Cardiovascular disease, Diseases [C] - Cardiovascular Diseases [C14]
 
 
TACTiC, NCT04964544: Technology-Assisted Cholesterol Trial in Consumers

Completed
3
1196
US
5 mg rosuvastatin calcium with a Web App (combination product), Crestor 5 mg
AstraZeneca, Concentrics Research LLC, Concentrics Research - STATKING JV, Idea Evolver, The Cleveland Clinic
High Cholesterol
03/23
03/23
NCT03527069: Efficacy and Safety of Cipros 10 Association on the Isolated Hypertriglyceridemia and Dyslipidemia Treatment

Recruiting
3
298
RoW
Cipros 10 association, EMS association, Crestor 10 mg, Rosuvastatin 10 mg
EMS
Hypertriglyceridemia, Dyslipidemia
06/24
02/25
NCT03540355: Efficacy and Safety of Cipros 20 Association on Dyslipidemia Treatment

Recruiting
3
312
RoW
Cipros 20 association, EMS Association, Crestor 20 mg, Rosuvastatin 20 mg
EMS
Dyslipidemias
11/23
02/24
NCT04603508: Efficacy and Safety of Berlim 25/10 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia

Not yet recruiting
3
240
NA
BERLIM 25/10 association, EMPAGLIFLOZIN, ROSUVASTATIN CALCIUM, BERLIM 25/10 ASSOCIATION PLACEBO, EMPAGLIFLOZIN PLACEBO, ROSUVASTATIN CALCIUM PLACEBO
EMS
Type 2 Diabetes Mellitus, Dyslipidemia
04/25
08/25
NCT04602754: Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.

Recruiting
3
228
RoW
BERLIM 25/20 ASSOCIATION, EMPAGLIFLOZIN PLACEBO, ROSUVASTATIN CALCIUM PLACEBO, EMPAGLIFLOZIN, ROSUVASTATIN CALCIUM, BERLIM 25/20 ASSOCIATION PLACEBO
EMS
Dyslipidemia Associated With Type II Diabetes Mellitus
04/25
08/25
2006-000978-68: Treatment of systemic effects in patients with COPD

Ongoing
2
100
Europe
acetylcysteine, rosuvastatin,
AstraZeneca
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease state characterized by airflow limitation that is not fully reverible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases, primarily caused by cigarette smoking.
 
 
NCT06048588: YN001 in Healthy Subjects and Patients With Coronary Atherosclerosis

Recruiting
1/2
130
RoW
YN001, Placebo for YN001, Placebo, rosuvastatin calcium tablets, Crestor®
Beijing Inno Medicine Co., Ltd.
Atherosclerotic Cardiovascular Disease
10/24
11/24
NCT02592317: A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate Cancer

Recruiting
1
20
Europe, RoW
JNJ 56021927, Drug Cocktail, Pioglitazone, Rosuvastatin
Aragon Pharmaceuticals, Inc.
Prostatic Neoplasms, Castration-Resistant
11/16
12/24
NCT03864042: Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

Active, not recruiting
1
56
Europe, Canada, US
losartan, dextromethorphan, caffeine, omeprazole, midazolam, rosuvastatin, bupropion immediate release (IR), encorafenib, binimetinib, modafinil
Pfizer, Pierre Fabre Laboratories
Advanced Solid Tumors, Metastatic Melanoma
07/22
06/23
NCT05594615: Drug-Drug Interaction Study Between EDP-235, Midazolam, Caffeine and Rosuvastatin in Healthy Subjects

Completed
1
24
US
EDP-235, Midazolam, Rosuvastatin, Caffeine
Enanta Pharmaceuticals, Inc
COVID-19
11/22
11/22
NCT05389722: A Study to Assess the Drug Levels of CC-92480 After Coadministration With Rifampin and Itraconazole, and the Drug Levels of Digoxin and Rosuvastatin After Coadministration With CC-92480 in Healthy Participants

Completed
1
24
US
CC-92480, BMS-986348, Rifampin, Itraconazole, Digoxin, Rosuvastatin
Bristol-Myers Squibb
Healthy Volunteers
11/22
11/22
NCT04887194: PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Completed
1
40
US
Sitravatinib, MGCD516, Warfarin, Coumadin, Dextromethorphan, Robitussin, Midazolam, Versed, Digoxin, LANOXICAPS, Rosuvastatin, Crestor, Nivolumab, OPDIVO
Mirati Therapeutics Inc.
Advanced Solid Tumor
12/22
12/22
NCT05652660: A Study to Understand the Effect of a Study Medicine Called ARV-471 on Rosuvastatin in Healthy Adults

Completed
1
12
US
ARV-471, PF-07850327, Rosuvastatin, CRESTOR®
Pfizer, Arvinas Estrogen Receptor, Inc.
Healthy
03/23
03/23
NCT05708573: Potential Drug Interaction Between ALXN2040 and Rosuvastatin

Completed
1
20
US
Rosuvastatin, ALXN2040
Alexion
Healthy Participants
03/23
04/23
NCT05763459: A Phase 1 Study of ABBV-CLS-7262, Rosuvastatin, and Digoxin in Healthy Subjects

Completed
1
12
US
ABBV-CLS-7262
Calico Life Sciences LLC, AbbVie
Healthy
05/23
06/23
NCT05787002: A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin.

Completed
1
16
US
AZD0780, Rosuvastatin
AstraZeneca
Dyslipidemia
05/23
05/23
NCT05789342: A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers

Completed
1
54
RoW
GP681, Rosuvastatin, Digoxin, Itraconazole, Oseltamivir
Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Healthy Volunteers
09/23
10/23
NCT05898672: A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin

Completed
1
12
Europe
Rosuvastatin, Nirmatrelvir/ritonavir
Pfizer
Pharmacokinetics, Healthy Volunteers
08/23
08/23
NCT05954624: Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid

Completed
1
49
RoW
Digoxin, Rosuvastatin, ZSP1273, Itraconazole, Probenecid
Guangdong Raynovent Biotech Co., Ltd
Drug Drug Interaction
11/23
11/23
NCT05788328: A Drug-Drug Interaction Study to Estimate the Effect of PF-07081532 on the Pharmacokinetics of Dabigatran and Rosuvastatin in Overweight or Obese Adult Participants

Terminated
1
16
US
Dabigatran etexilate (DE), Pradaxa, Rosuvastatin, Crestor, PF-07081532, Lotiglipron
Pfizer
Healthy
09/23
09/23
NCT03720366: A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients

Completed
1
40
RoW
enasidenib, CC-90007, AG-221, Arm 1 probes, Arm 2 Probes, Arm 3 probes
Celgene
Leukemia, Myeloid, Acute
09/23
12/23
NCT05981365: Voxelotor CYP and Transporter Cocktail Interaction Study

Completed
1
44
US
Voxelotor, Oxbryta, Bupropion, Wellbutrin, Repaglinide, Prandin, Flurbiprofen, Ansaid, Omeprazole, Prilosec, Midazolam, Dormicum, Metformin, Glucophage, Furosemide, Lasix, Rosuvastatin, Crestor
Pfizer
Sickle Cell Disease
10/23
10/23
NCT05906836: A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

Completed
1
32
US
Rosuvastatin, Selpercatinib, LY3527723, LOXO-292, Retevmo®
Eli Lilly and Company
Healthy
10/23
10/23
NCT06031454: Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin

Completed
1
56
RoW
Midazolam, Omeprazole, Rosuvastatin, Verapamil, Rifampin, Leritrelvir
Guangdong Raynovent Biotech Co., Ltd
Drug Drug Interaction
11/23
12/23
NCT06081166: A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin

Completed
1
74
Canada
Obicetrapib, tablets, Atorvastatin Calcium, Rosuvastatin Calcium
NewAmsterdam Pharma, Pharma Medica Research, Inc.
Healthy Volunteers
12/23
01/24
NCT06191991: A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Active, not recruiting
1
27
US
Atorvastatin, ALG-055009, Rosuvastatin
Aligos Therapeutics
Healthy Volunteers
03/24
06/24
NCT06092931: A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Completed
1
28
US
DC-806, Midazolam, Repaglinide, Digoxin, Rosuvastatin
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
Healthy Participants
11/23
11/23
NCT06475872: Study to Evaluate the Bioequivalence of "Crecheck Tablet 2.5 mg (Rosuvastatin Calcium)" and "Crestor Tablet 5 mg (Rosuvastatin Calcium)" in Healthy Adult Subjects

Completed
1
36
RoW
Crecheck Tablet 2.5 mg, Rosuvastatin Calcium, Crestor Tablet 5 mg
Hanlim Pharm. Co., Ltd.
Primary Hypercholesterolemia, Combined Hyperlipidemia
12/23
12/23
NCT06162169: A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects

Completed
1
66
RoW
JAB-21822, Itraconazole, Omeprazole, Midazolam , Rosuvastatin calcium and digoxin, Rifampicin
Jacobio Pharmaceuticals Co., Ltd.
Healthy Subjects
02/24
02/24
NCT06186622: A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

Active, not recruiting
1
50
US
Orforglipron, LY3502970, Simvastatin, Digoxin, Rosuvastatin, Acetaminophen, Midazolam, Sodium Bicarbonate
Eli Lilly and Company
Healthy, Obese, Overweight
06/24
06/24
NCT06111521: A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants

Not yet recruiting
1
56
US
LY3537982, Digoxin, Rosuvastatin, Midazolam
Eli Lilly and Company, Loxo Oncology, Inc.
Healthy
01/24
01/24
NCT06293742: ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Recruiting
1
64
US
ECC5004, Midazolam, Rosuvastatin, Digoxin, Atorvastatin
Eccogene
Type 2 Diabetes Mellitus
04/24
04/24
NCT06279234: A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Recruiting
1
122
US
Placebo, Rosuvastatin, Midazolam, Omeprazole, PF-06954522
Pfizer
Type 2 Diabetes Mellitus (T2DM), Obesity
12/24
12/24
NCT05738291: A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood

Completed
1
67
Europe
BI 1839100, Placebo matching BI 1839100, midazolam, digoxin, rosuvastatin
Boehringer Ingelheim
Healthy
06/24
06/24
NCT05384262: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects

Active, not recruiting
1
183
Europe, US
AZD0780, Placebo, Rosuvastatin
AstraZeneca, Parexel
Dyslipidemia
06/24
06/24
NCT06329895: A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants

Recruiting
1
15
Europe
BAY2927088, Dabigatran etexilate, Rosuvastatin
Bayer
Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers
05/24
05/24
NCT06105255: A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553

Active, not recruiting
1
44
RoW
D-1553, other
InventisBio Co., Ltd
Healthy Male
03/24
07/24
NCT06348290: Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects

Not yet recruiting
1
72
NA
JMKX001899, Itraconazole, Midazolam, Rifampin, dextromethorphan, Rosuvastatin, digoxin
Jemincare
Solid Tumor, Adult
05/24
09/24
NCT05926180: Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19)

Recruiting
1
31
RoW
DZD9008 and Probe drugs (midazolam, digoxin, rosuvastatin), Inapplicable
Dizal Pharmaceuticals
Non-small Cell Lung Cancer
08/24
08/24
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

Recruiting
N/A
1600
Canada, US
Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine
Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
09/24
09/24

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