| rosuvastatin / Generic mfg. |
NCT05763459: A Phase 1 Study of ABBV-CLS-7262, Rosuvastatin, and Digoxin in Healthy Subjects |
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| Completed | 1 | 12 | US | ABBV-CLS-7262 | Calico Life Sciences LLC, AbbVie | Healthy | 05/23 | 06/23 | | |
NCT05787002: A Study to Assess the Effect of AZD0780 on the Pharmacokinetics of Rosuvastatin. |
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| Completed | 1 | 16 | US | AZD0780, Rosuvastatin | AstraZeneca | Dyslipidemia | 05/23 | 05/23 | | |
NCT05789342: A Study to Evaluate the Drug-drug Interactions (DDIs) of GP681 With Rosuvastatin, Digoxin, Itraconazole, Oseltamivir in Chinese Healthy Volunteers |
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| Completed | 1 | 54 | RoW | GP681, Rosuvastatin, Digoxin, Itraconazole, Oseltamivir | Jiangxi Qingfeng Pharmaceutical Co. Ltd. | Healthy Volunteers | 09/23 | 10/23 | | |
NCT05898672: A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin |
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| Completed | 1 | 12 | Europe | Rosuvastatin, Nirmatrelvir/ritonavir | Pfizer | Pharmacokinetics, Healthy Volunteers | 08/23 | 08/23 | | |
NCT05954624: Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid |
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| Completed | 1 | 49 | RoW | Digoxin, Rosuvastatin, ZSP1273, Itraconazole, Probenecid | Guangdong Raynovent Biotech Co., Ltd | Drug Drug Interaction | 11/23 | 11/23 | | |
NCT05788328: A Drug-Drug Interaction Study to Estimate the Effect of PF-07081532 on the Pharmacokinetics of Dabigatran and Rosuvastatin in Overweight or Obese Adult Participants |
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| Terminated | 1 | 16 | US | Dabigatran etexilate (DE), Pradaxa, Rosuvastatin, Crestor, PF-07081532, Lotiglipron | Pfizer | Healthy | 09/23 | 09/23 | | |
NCT03720366: A Study of Perpetrator Drug Interactions of Enasidenib in AML Patients |
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| Completed | 1 | 40 | RoW | enasidenib, CC-90007, AG-221, Arm 1 probes, Arm 2 Probes, Arm 3 probes | Celgene | Leukemia, Myeloid, Acute | 09/23 | 12/23 | | |
NCT05981365: Voxelotor CYP and Transporter Cocktail Interaction Study |
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| Completed | 1 | 44 | US | Voxelotor, Oxbryta, Bupropion, Wellbutrin, Repaglinide, Prandin, Flurbiprofen, Ansaid, Omeprazole, Prilosec, Midazolam, Dormicum, Metformin, Glucophage, Furosemide, Lasix, Rosuvastatin, Crestor | Pfizer | Sickle Cell Disease | 10/23 | 10/23 | | |
NCT05906836: A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants |
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| Completed | 1 | 32 | US | Rosuvastatin, Selpercatinib, LY3527723, LOXO-292, Retevmo® | Eli Lilly and Company | Healthy | 10/23 | 10/23 | | |
NCT06031454: Drug-durg Interaction of Leritrelvir(RAY1216) With Midazolam, Omeprazole, Rosuvastatin, Verapamil, and Rifampin |
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| Completed | 1 | 56 | RoW | Midazolam, Omeprazole, Rosuvastatin, Verapamil, Rifampin, Leritrelvir | Guangdong Raynovent Biotech Co., Ltd | Drug Drug Interaction | 11/23 | 12/23 | | |
ChiCTR2300072490: A single-center, open, fixed-sequence phase I clinical study to evaluate the pharmacokinetics of multiple doses of Desidustat Tablets on a single dose of rosuvastatin calcium tablets in healthy subjects |
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| Not yet recruiting | 1 | 24 | | Desidustat tablets 150 mg, D4, D6, D8, D10, administered 4 times, Bupropion hydrochloride sustained-release tablets 150 mg, D1, D10, administered twice | Henan Privince Hospital of Traditional Chinese Medicine; Kangzhe (Hunan) Pharmaceutical Co., Ltd., Sponsor | Renal anemia | | | | |
NCT06081166: A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin |
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| Completed | 1 | 74 | Canada | Obicetrapib, tablets, Atorvastatin Calcium, Rosuvastatin Calcium | NewAmsterdam Pharma, Pharma Medica Research, Inc. | Healthy Volunteers | 12/23 | 01/24 | | |
NCT06191991: A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies) |
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| Active, not recruiting | 1 | 27 | US | Atorvastatin, ALG-055009, Rosuvastatin | Aligos Therapeutics | Healthy Volunteers | 03/24 | 06/24 | | |
NCT06092931: A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants |
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| Completed | 1 | 28 | US | DC-806, Midazolam, Repaglinide, Digoxin, Rosuvastatin | DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company | Healthy Participants | 11/23 | 11/23 | | |
NCT06475872: Study to Evaluate the Bioequivalence of "Crecheck Tablet 2.5 mg (Rosuvastatin Calcium)" and "Crestor Tablet 5 mg (Rosuvastatin Calcium)" in Healthy Adult Subjects |
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| Completed | 1 | 36 | RoW | Crecheck Tablet 2.5 mg, Rosuvastatin Calcium, Crestor Tablet 5 mg | Hanlim Pharm. Co., Ltd. | Primary Hypercholesterolemia, Combined Hyperlipidemia | 12/23 | 12/23 | | |
NCT06162169: A Clinical Trial to Evaluate JAB-21822 Drug-drug Interactions in Healthy Subjects |
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| Completed | 1 | 66 | RoW | JAB-21822, Itraconazole, Omeprazole, Midazolam , Rosuvastatin calcium and digoxin, Rifampicin | Jacobio Pharmaceuticals Co., Ltd. | Healthy Subjects | 02/24 | 02/24 | | |
ChiCTR2100048407: A randomized controlled trial of rosuvastatin in the prevention of deep vein thrombosis in total knee arthroplasty |
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| Recruiting | 1 | 226 | | Fondaparinux sodium ;Rosuvastatin + fondaparinux sodium | The Third Hospital of Mianyang, Sichuan Mental Health Center; The Third Hospital of Mianyang, Science and technology project of Sichuan province | End-stage knee disease | | | | |
| Active, not recruiting | 1 | 20 | US | Rosuvastatin, Crestor, Rosuvastatin (Inhibitor arm), Cresto, Eltrombopag, Promacta | University of California, San Francisco, Food and Drug Administration (FDA) | Healthy Volunteers | 12/24 | 12/24 | | |
NCT06186622: A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants |
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| Active, not recruiting | 1 | 50 | US | Orforglipron, LY3502970, Simvastatin, Digoxin, Rosuvastatin, Acetaminophen, Midazolam, Sodium Bicarbonate | Eli Lilly and Company | Healthy, Obese, Overweight | 06/24 | 06/24 | | |
NCT06111521: A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants |
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| Not yet recruiting | 1 | 56 | US | LY3537982, Digoxin, Rosuvastatin, Midazolam | Eli Lilly and Company, Loxo Oncology, Inc. | Healthy | 01/24 | 01/24 | | |
NCT06293742: ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants |
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| Recruiting | 1 | 64 | US | ECC5004, Midazolam, Rosuvastatin, Digoxin, Atorvastatin | Eccogene | Type 2 Diabetes Mellitus | 04/24 | 04/24 | | |
NCT06279234: A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus |
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| Recruiting | 1 | 122 | US | Placebo, Rosuvastatin, Midazolam, Omeprazole, PF-06954522 | Pfizer | Type 2 Diabetes Mellitus (T2DM), Obesity | 12/24 | 12/24 | | |
NCT05738291: A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood |
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| Completed | 1 | 67 | Europe | BI 1839100, Placebo matching BI 1839100, midazolam, digoxin, rosuvastatin | Boehringer Ingelheim | Healthy | 06/24 | 06/24 | | |
NCT05384262: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects |
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| Active, not recruiting | 1 | 183 | Europe, US | AZD0780, Placebo, Rosuvastatin | AstraZeneca, Parexel | Dyslipidemia | 06/24 | 06/24 | | |
NCT06329895: A Study to Learn About How BAY2927088 Affects the Level of Dabigatran or Rosuvastatin in the Blood When These Drugs Are Taken Together in Healthy Participants |
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| Recruiting | 1 | 15 | Europe | BAY2927088, Dabigatran etexilate, Rosuvastatin | Bayer | Advanced Non-small Cell Lung Cancer, EGFR Mutation, HER2 Mutation, Healthy Volunteers | 05/24 | 05/24 | | |
NCT06105255: A Study to Evaluate the Effects of D-1553 on PK of Midazolam, Caffeine, Rosuvastatin, Furosemide, Digoxin, and Itraconazole or Omeprazole on PK of D-1553 |
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| Active, not recruiting | 1 | 44 | RoW | D-1553, other | InventisBio Co., Ltd | Healthy Male | 03/24 | 07/24 | | |
NCT06348290: Study to Evaluate the Drug-drug Interaction of JMKX001899 in Healthy Subjects |
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| Not yet recruiting | 1 | 72 | NA | JMKX001899, Itraconazole, Midazolam, Rifampin, dextromethorphan, Rosuvastatin, digoxin | Jemincare | Solid Tumor, Adult | 05/24 | 09/24 | | |
| Recruiting | 1 | 50 | US | Rosuvastatin 10mg | Children's Mercy Hospital Kansas City | Cholesterol; Lipidosis | 01/25 | 01/25 | | |
BASiC-CIC, NCT06304896: Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy |
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| Not yet recruiting | 1 | 150 | RoW | Carvedilol, Carvid, Coreg, Ramipril, Tritace, Altace, Rosuvastatin, Crestor, Colchicine, Colcrys, Mitigare, Placebo | Arab Contractors Medical Centre | Chemotherapy Induced Systolic Dysfunction | 05/25 | 12/25 | | |
NCT05926180: Assessing the Effect of DZD9008 on the Pharmacokinetics of the Cocktail Probes Representative for CYP3A4, P-gp, BCRP and OATP1B1 in Patients With EGFR or HER2 Mutant Advanced Non-small Cell Lung Cancer (WU-KONG19) |
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| Recruiting | 1 | 31 | RoW | DZD9008 and Probe drugs (midazolam, digoxin, rosuvastatin), Inapplicable | Dizal Pharmaceuticals | Non-small Cell Lung Cancer | 08/24 | 08/24 | | |
NCT06105060: Clinical Effects of New Approach on Patients With Non-alcoholic Steatohepatitis |
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| Not yet recruiting | 1 | 160 | NA | Rosuvastatin 20mg, N-acetyl cysteine, Rosuvastatin and N-acetyl cysteine, Vita-E | Beni-Suef University | Non-alcoholic Steatohepatitis | 10/24 | 01/25 | | |
NCT05912387: Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study |
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| Recruiting | 1 | 15 | US | Rosuvastatin | Stanford University | Primary Sclerosing Cholangitis, Inflammatory Bowel Diseases | 05/25 | 12/25 | | |
ChiCTR-IOR-15006664: The effects of rosuvastatin on retinal vessels in hypercholesterolemic patients with low-to-moderate risk of coronary artery disease |
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| Not yet recruiting | N/A | 150 | | rosuvastatin 10mg qn+aspirin 100mg qd ;aspirin 100mg qd | Beijing Tongren Hospital; Beijing Tongren Hospital, AstraZeneca | Coronary artery disease | | | | |
ChiCTR-TRC-06000677: A Randomized, Open-labebeled, Parallel, Comparative Study of the Efficacy and Tolerability of Rosuvastatin in LDL-C Reduction Using Different Dosing Regimes of 5mg Daily, 10mg Daily and 10mg Alternate day in Hong Kong Chinese Type 2 Diabetic Patients |
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| Completed | N/A | 120 | | rosuvastatin 5 mg daily or 10 mg daily or 10 mg on alternate days versus Rosuvastatin 10mg alt day is compared with Rosuvastatin 5mg qd and Rosuvastatin 10mg qd for 24 weeks | Dr Francis C.C. Chow; Dr Risa Ozaki Dr Alice P.S. Kong Dr Wing Yee So Dr Wing Bun Chan Dr Winnie W.Y. Lau Dr Anglea Y.S. Cheng Dr Linda Yu Dr Andrea Luk Dr Dicky Cheung Dr Dr C.Y. Yeung Dr H.K. Pang Dr I.M. Wong, Chinese University of Hong Kong (investigator-initiated study) AstraZeneca Limited | hyperliipidaemia | | | | |
ChiCTR-IOR-17013595: Effets of Qishen Yiqi Dripping pill on serum resistin and related factors in patients with stable angina pectoris of coronary artery disease: single blind, placebo and randomized controlled trial |
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| Completed | N/A | 100 | | Aspirin, rosuvastatin calcium tablets, metoprolol sustained-release tablets, isosorbide mononitrate tablets, qishen yiqi drop pills ; Aspirin, rosuvastatin calcium tablets, metoprolol sustained-release tablets, isosorbide mononitrate tablets,placebo | Weifang City People's Hospital; Weifang City People's Hospital, Weifang City Science and Technology Development Project 2015WF004 | Stable angina | | | | |
| Completed | N/A | 64 | | All patients received 10 mg/day of rosuvastatin for 4-8 weeks | Dalian Medical University; First Affiliated Hospital, Dalian Medical University, National Program on Key Basic Research Project of China | Hyperlipidemia | | | | |
| Recruiting | N/A | 320 | | 20mg/d rosuvastatin treated within 24 hours by oral or gastric tube is applying in intense rosuvastatin group in 2 weeks . ;5mg/d rosuvastatin treated within 24 hours by oral or gastric tube is applying in conventional rosuvastatin group in 2 weeks . | The First Affiliated Hospital of Jinan University; The First Affiliated Hospital of Jinan University, Science and Technology Program of Guangzhou 1561000289, Science and Technology Program of Guangzhou 155700029 | Ischemic Cerebrovascular Disease | | | | |
ChiCTR1800019031: A study for lipoprotein particle size on risk of cardiovascular events in patients with coronary artery disease and statin intervention |
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| Completed | N/A | 100 | | Rosuvastatin | FuWai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; Fuwai Hospital, Capital Health Development Research Project | Coronary Heart Disease | | | | |
INTENSITY-HIGH, NCT03355027: Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease |
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| Active, not recruiting | N/A | 60 | Europe | Alirocumab 150 MG/ML, Praluent, Ezetimibe 10Mg Tablet, Ezetrol, Atorvastatin 40Mg Tablet, Atorvastatin 80Mg Tablet, Rosuvastatin 20Mg Tablet, Crestor, Rosuvastatin 40Mg Tablet, Simvastatin 80mg | Cambridge University Hospitals NHS Foundation Trust, University of Cambridge | Atherosclerosis, Cardiovascular Diseases | 09/19 | 11/23 | | |
TITOCNI, ChiCTR1800014908: Comparison the efficacy and safety of ticagrelor and TEG-optimized clopidogrel on emergency PCI for patients with acute non-ST segment-elevation myocardial infarction |
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| Not yet recruiting | N/A | 2000 | | 180mg loading dose of ticagrelor, followed by 90mg q12h.; 600mg loading dose of clopidogrel, with TEG-guided upstream tirofiban, followed by clopidogrel 75mg/day ;Rosuvastatin of 20mg are given twice in the first 24 hours, followed by 20mg/day ;Rosuvastatin are given 5mg/day | Tianjin Cardiogy Institue; Level of the institution：, Health and Family Planning Commision of Tianjin | acute non-ST-elevation myocardial infarction | | | | |
NCT06094244: Statins in Patients With Spontaneous Intracerebral Hemorrhage |
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| Completed | N/A | 153 | Europe | Atorvastatin, Rosuvastatin, No drugs | Pomeranian Medical University Szczecin | Intracerebral Hemorrhage | 12/20 | 03/21 | | |
ChiCTR2000037306: A randomized controlled clinical study of rosuvastatin combined with carvedilol in the prevention of complications of portal hypertension due to cirrhosis guided by HVPG |
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| Recruiting | N/A | 220 | | Rosuvastatin combined with carvedilol ;carvedilol | Shanghai Public Health Clinical Center; Shanghai Public Health Clinical Center, Shanghai Shenkang Hospital Development Center | liver cirrhosis | | | | |
NCT04974814: Effect of Statin Preloading in STEMI in Improving PCI Outcomes |
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| Recruiting | N/A | 99 | RoW | Rosuvastatin 40mg, Atorvastatin 80mg, Control Test | Beni-Suef University | ST Elevation Myocardial Infarction | 10/22 | 04/23 | | |
| Completed | N/A | 195 | US | statin, evolocumab | Icahn School of Medicine at Mount Sinai | Coronary Artery Disease | 10/22 | 10/22 | | |
ChiCTR2100052605: Drug-Drug interaction research of atorvastatin and rosuvastatin on the pharmacokinetics and pharmacodynamics of clopidogrel in vivo |
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| Recruiting | N/A | 12 | | Atorvastatin ;Rosuvastatin | Xiangya Hospital, Central South University; Xiangya Hospital, Central South University, Natural Science Foundation of Hunan Province and Self-funded | N/A | | | | |
NCT04744571: Safety and Efficacy of Drug-Coated Balloon Angioplasty for the Treatment of Chronic Total Occlusions |
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| Enrolling by invitation | N/A | 200 | RoW | aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor, Optimal medical therapy, coronary wires. or coronary balloons, drug-coated balloon, drug-eluting stent | Beijing Anzhen Hospital | Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention, Chronic Total Occlusion of Coronary Artery, Drug-Eluting Stents | 12/22 | 01/23 | | |
| Completed | N/A | 36 | RoW | Test Drug, Vaptor 20 mg Tablet, Reference Drug, Crestor 20 mg Tablet | University of Karachi, The Searle Company Limited | Healthy Individuals | 12/22 | 12/22 | | |
NCT04699279: Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Rosuvastatin) I |
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| Recruiting | N/A | 300 | RoW | Rosuvastatin 10mg | Nanjing Medical University, Beijing Anzhen Hospital | Acute Aortic Syndrome, Aortopathy | 12/23 | 12/23 | | |
| Not yet recruiting | N/A | 105 | NA | rosuvastatin, ststins | Assiut University | Stroke, Acute | 02/25 | 08/25 | | |
NCT03511118: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants |
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| Recruiting | N/A | 1600 | Canada, US | Tranexamic acid (TXA), labetalol, metformin, nifedipine, clindamycin, oxycodone, azithromycin, escitalopram, sertraline, ondansetron, Ciprofloxacin, Doxycycline, Levofloxacin, Methylphenidate, Sumatriptan, Citalopram, Cyclobenzaprine, Furosemide, Gabapentin, Hydrochlorothiazide, Hydroxyurea, Rosuvastatin, Topiramate, Trazodone, Valganciclovir, Venlafaxine, Verapamil, Remdesivir, Anakinra, Tocilizumab, Fluvoxamine, Amoxicillin, Bupropion, Duloxetine, Hydrocodone, Levetiracetam, Paroxetine, Buprenorphine | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI | 09/24 | 09/24 | | |
ChiCTR2300067905: High-Resolution Assessment of extracranial Plaques in a multiple centers Evolocumab Randomized Study |
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| Not yet recruiting | N/A | 200 | | 140 mg of evolocumab by subcutaneous injection every 2 weeks; continuous administration for 26 weeks, of which a total of 13 doses of evolocumab ;Atorvastatin 40mg/day or rosuvastatin 20mg/day for 26 weeks | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, self-financing | acute ischemic stroke | | | | |
ChiCTR2300072544: Experimental and clinical studies on intervention of lower extremity arteriosclerosis obliteration by Sichong tablet through regulation of TNF-NF-κb signal pathway |
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| Not yet recruiting | N/A | 80 | | Sichong tablet + Aspirin/Clopidogrel + Rosuvastatin ;Aspirin/Clopidogrel + Rosuvastatin | Ji'nan Municipal Hospital of Traditional Chinese Medicine; Ji'nan Municipal Hospital of Traditional Chinese Medicine, Jinan Clinical Science and Technology Innovation Program | lower extremity arteriosclerosis obliteration | | | | |
ChiCTR2300071936: Clinical evaluation of Jiang Zhi Qing Shen Capsules in the treatment of hyperlipidemia (phlegm and turbidity blocking type) |
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| Recruiting | N/A | 120 | | Rosuvastatin + Jiang Zhi Qing Shen Capsules ;Rosuvastatin + placebo | Zhengzhou Chinese Hospital ; Zhengzhou Chinese Hospital, Henan Provincial Health and Wellness Commission,Zhengzhou Chinese Hospital | Dyslipidemia | | | | |
RADICALPC, NCT03127631: A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients |
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| Recruiting | N/A | 6000 | Canada, US, RoW | Nutrition, Exercise, Smoking cessation, Statin (such as Simvastatin, Atorvastatin, Rosuvastatin, Pravastatin), ACE inhibitor | McMaster University, Prostate Cancer Canada, Canadian Cancer Society (CCS) | Prostate Cancer, Cardiovascular Disease | 12/25 | 12/25 | | |
NCT04847752: Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis |
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| Recruiting | N/A | 1000 | RoW | carotid artery stenting, CAS, carotid endarterectomy, CEA, Aspirin, ASP, Clopidogrel, plavix, Anticoagulant, warfarin, rivaroxaban, dabigatran, any other anticoagulant therapy, Statin, atorvastatin, rosuvastatin, any other statin drugs, PCSK9 inhibitor, Evolocumab, Alirocumab, any other PCSK9 inhibitors | Tongji Hospital | Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis) | 12/26 | 12/28 | | |
ACTRN12607000473460: Study to evaluate the efficacy and safety of rosuvastatin in indian population who have diabetes with abnormal lipid levels (dyslipidemia) |
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| Recruiting | N/A | 360 | | | Ranbaxy Laboratories Ltd, Ranbaxy Laboratories Ltd | Dyslipidemia in patients with Diabetes Mellitus | | | | |