| methylprednisolone acetate / Generic mfg. |
| Ongoing | 4 | 704 | Europe | Methylprednisolone acetate, Triamcinolone acetonide, Injection, Solution for injection, Depo-Medrone, Kenalog | University of Oxford, NIHR Health Technology Assessment Programme | Pulmonary Hypertension, Right heart failure | | | | |
NCT00863889: Steroid Injection for the Treatment of Greater Trochanteric Pain Syndrome |
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| Withdrawn | 4 | 0 | US | Depomedrol injection, Lidocaine, Marcaine | Emory University | Bursitis | 02/10 | 02/10 | | |
NCT01144143: Treatment Of Knee Osteoarthritis With Intra-Articular Infliximab |
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| Completed | 4 | 16 | US | Infliximab, Placebo, Standard of Care: Methylprednisolone acetate | Herbert Lindsley, MD, Centocor, Inc. | Osteoarthritis of the Knee | 12/10 | 01/11 | | |
2010-021061-72: To evaluate the safety and efficacy of a single subconjunctival injection of methylprednisolone versus standard postoperative steroid regiment in terms of intraocular inflammation and intraocular pressure following uncomplicated phacoemulsification surgery. |
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| Ongoing | 4 | 50 | Europe | Eye drops, suspension, Suspension for injection, Isopto-Maxidex, Depo-Medrol injektionsvätska. | Ögonkliniken, Akademiska sjukhuset i Uppsala | Att studera säkerheten och effekten av en engångs subkonjunktival injektion med metylprednisolon jämfört med sedvanliga postoperativa kortisonbehandling med ögondroppar avseende intraokulär tryckstegring och intraokulär inflammation efter en okomplicerad kataraktoperation. | | | | |
| Completed | 4 | 44 | Europe | methylprednisolone acetate, Depo-medrol, Triamcinolone Acetonide, Triamvirgi | Istituto Ortopedico Rizzoli, Azienda Ospedaliera San Giovanni Battista | Tendinopathy, Adrenal Insufficiency | 05/13 | 05/13 | | |
LESS, NCT01238536: Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial ( Trial) |
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| Completed | 4 | 400 | US | Epidural steroid with local anesthetic injection, Epidural local anesthetic injection, Epidural steroid injection, Kenalog, depo-medrol, betamethasone or dexamethasone, lidocaine | University of Washington, Kaiser Permanente, University of California, San Francisco, Henry Ford Hospital, Harvard Pilgrim Health Care, Harvard Vanguard Medical Associates, University of Colorado, Denver, Mayo Clinic, Stanford University, Massachusetts General Hospital, Virginia Spine Research Institute, Oregon Health and Science University, Dallas VA Medical Center | Spinal Stenosis, Low Back Pain | 08/13 | 09/15 | | |
NCT02176304: Does Injection Site Matter? A Randomized Controlled Trial to Evaluate Efficacy of Knee Intraarticular Injections on Improval of Patient Reported Outcomes. |
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| Completed | 4 | 60 | US | Depomedrol, Depomedrol 40 mg/ml, Lidocaine, Lidocaine 2% | University of Puerto Rico | Knee Osteoarthritis | 09/14 | 12/14 | | |
NCT01994759: Optimal Treatment of Plantar Fasciitis: Physical Training, Glucocorticoid Injections or a Combination Thereof. |
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| Completed | 4 | 90 | Europe | Training, Heavy slow resistance exercise, Eccentric training, stretching, Glucocorticosteroid injection, Methylprednisolone, Depo-medrol, Reduction in impact, Shock absorbtion | Bispebjerg Hospital, Fonden for Faglig Udvikling af Speciallægepraksis, Denmark | Plantar Fasciitis | 07/15 | 12/16 | | |
NCT02140632: Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome |
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| Completed | 4 | 50 | RoW | Local methylprednisolone acetate and lidnocaine injection, depomedrol with lidnocaine, wrist splinting | Kwong Wah Hospital | Carpal Tunnel Syndrome, Local Steroid Injection, Wrist Splinting | 12/15 | 12/15 | | |
2004-004591-37: Efficacy of intrarticular steroid injection in osteoarthritis of the first carpometacarpal joint (CMCJ). |
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| Ongoing | 4 | 154 | Europe | METHYLPREDNISOLONE ACETATE 40mg, Bupivocaine Hydrochloride 0.5%, DEPO-MEDRONE, Marcain, DEPO-MEDRONE, Marcain | Leeds teaching Hospitals | Osteoarthritis of the 1st carpometacarpal joint (CMCJ) | | | | |
2007-004947-31: Injectie van autologe bloedplaatjes bij epicondylitis lateralis |
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| Ongoing | 4 | 100 | Europe | corticosteroid, Depo-Medrol met Lidocaïne, | Biomet Nederland BV | Tennis elbow, also known as lateral epicondylitis | | | | |
2008-003952-31: Treatment of chronic rotator cuff tendinopathy with local steroid injection or hypertermia. A Randomized, prospective, clinical study. |
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| Completed | 4 | 160 | Europe | DEPOMEDROL+LID.*1F 1ML+1SIR, DEPOMEDROL+LID.*1F 1ML+1SIR | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI | rotator cuff tendinopathy | | | | |
| Completed | 4 | 50 | Europe | 1. Methylprednisolone acetate with lidocaine hydrochloride, Lidocaine hydrochloride, Depo-Medrone with Lidocaine, Lidocaine Hydrochloride Injection B.P. 1% w/v, Depo-Medrone with Lidocaine, Lidocaine Hydrochloride Injection B.P. 1% w/v | University of Oxford | Rotator cuff tendinopathyAdhesive capsulitis of the shoulder joint | | 03/13 | | |
2010-022106-40: Longterm Effects of Intraarticular Hyaluronan vs Corticosteroid in Osteoarthritis of the Hip: A Randomized Controlled Trial |
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| Ongoing | 4 | 300 | Europe | Depomedrol, RVG 00605, Depomedrol, Depomedrol | | coxarthrosis | | | | |
2011-003207-37: COMPARISON BETWEEN INTRA-ARTICULAR INJECTION OF CORTICOSTEROIDS AND INTRA-ARTICULAR INJECTION OF HYALURONIC ACID IN THE TREATMENT OF ROTATOR CUFF TENDINOPATHY. A PROSPECTIVE CLINICAL TRIAL. CONFRONTO TRA TERAPIA INFILTRATIVA CON CORTICOSTEROIDI E TERAPIA INFILTRATIVA CON ACIDO IALURONICO NEL TRATTAMENTO DELLA TENDINOPATIA DELLA CUFFIA DEI ROTATORI. STUDIO CLINICO PROSPETTICO RANDOMIZZATO |
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| Ongoing | 4 | 92 | Europe | ORTHOVISC SIR 2ML 15MG/ML 1PZ, DEPOMEDROL*1FL 40MG 1ML, ORTHOVISC SIR 2ML 15MG/ML 1PZ, DEPOMEDROL*1FL 40MG 1ML | POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI, Policlinico Universitario Agostino Gemelli | ROTATOR CUFF TENDINOPATHY tendinopatia cuffia dei rotatori | | | | |
NCT02576249: Corticosteroid/Ropivacaine Versus Corticosteroid/Saline Injections for Knee Osteoarthritis |
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| Completed | 4 | 29 | US | Ropivacaine, Naropin, Normal saline, Sodium Chloride, Methylprednisolone, Depo-Medrol | Mayo Clinic | Osteoarthritis | 07/16 | 10/16 | | |
2016-001906-41: A randomised control trial of knee injections for relief of pain in osteoarthritis: A comparison of corticosteroid and NSAID injections |
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| Ongoing | 4 | 78 | Europe | Ketorolac Trometamol, Methylprednisolone Acetate, SUB02835MIG, SUB03255MIG, Solution for injection, Ketorolac Trometamol, Depo-medrone (Methylprednisolone Acetate) | Royal College of Surgeons in Ireland, Dept of Orthopaedic Surgery, MRHT, Tullamore, Co Offaly | Knee osteoarthritis is the condition of interest. Osteoarthritis is a common musculoskeletal complaint, with an underlying pathogenesis related to bio-mechanical stress loading, resulting in initial changes within the articular cartilage, progressing to develop cartilage fibrillation; vertical clefts and eventual exposure of subchondral bone and eburnation, Knee osteoarthritis is the condition of interest, which is a condition characterised by the wearing down of the protective cartilage within the knee, Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
NCT02652390: Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome |
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| Completed | 4 | 111 | NA | Methylprednisolone 80 mg, Depo-Medrol, Methylprednisolone 40 mg, Saline, Sodium chloride solution | Region Skane | Carpal Tunnel Syndrome | 10/16 | 10/16 | | |
NCT02448316: Plantar Fasciitis, Operation or Conservative Treatment |
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| Completed | 4 | 30 | Europe | endoscopic surgery, Fascial release, Heel spur resection, Training, methylprednisolon, Depo-medrol, Glucocorticosteroid injection, lidokaine, Xylocain, strength training, stretching | Bispebjerg Hospital, The Danish Rheumatism Association | Plantar Fasciitis | 11/16 | 11/17 | | |
NCT01995019 / 2013-003365-34: Arthralgia of the Temporomandibular Joint. Pain Relief Following One Intra-articular Injection of Methylprednisolone |
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| Completed | 4 | 56 | Europe | Methylprednisolone, Depo-Medrol 40 mg/ml, Physiologic saline, Sham substance | Uppsala University | Arthralgia, TMJ | 03/17 | 03/17 | | |
CALCECHO, NCT02403856: Efficacy and Tolerance of Ultrasound-guided Needling and Lavage of Calcific Tendinitis of the Rotator Cuff Performed With or Without Subacromial Corticosteroid Injection |
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| Completed | 4 | 136 | Europe | Sodium Chloride 0.9%, NaCl 0.9%, Methylprednisolone acetate, Dépomédrol, Ultrasound-guided Needling and Lavage | Nantes University Hospital | Calcifying Tendinitis of Shoulder | 04/17 | 11/17 | | |
NCT02847494: Corticosteroids for Acute Migraine in the Emergency Department |
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| Completed | 4 | 220 | US | metoclopramide, Dexamethasone, methylprednisolone acetate | Montefiore Medical Center | Migraine | 09/17 | 09/17 | | |
IPACK, NCT03094663: Adductor Canal Block With Periarticular Injection and (ACB/PAI/) Versus Periarticular Injection (PAI) |
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| Completed | 4 | 86 | US | Bupivacaine with epinephrine, Sensorcaine/Epinephrine, Sensorcaine-MPF/Epinephrine, Marcaine-Epinephrine (PF), Methylprednisolone, Depo-Medrol, Solu-Medrol, Medrol, Cefazolin, cephalosporin antibiotics, 8 MHz. Chiba needle, Bupivacaine with Dexamethasone, dexamethasone to non-liposomal bupivacaine, Bupivacaine 25cc, Exparel, Marcaine, Marcaine Spinal (PF), Bupivacaine 20cc, Dexamethasone, Ozurdex, Maxidex, DexPak 6 Day | Hospital for Special Surgery, New York | Knee Arthropathy | 05/18 | 09/18 | | |
2018-001085-42: POISE - Psoriatic Oligoarthritis Intervention with Symptomatic thErapy |
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| Not yet recruiting | 4 | 60 | Europe | Methylprednisolone acetate BP, Triamcinolone acetonide, Injection, Methylprednisolone acetate BP, Triamcinolone acetonide | University of Oxford, NIHR | Psoriatic Arthritis (PsA) is an inflammatory arthritis. PsA is a highly heterogenous disease with a proportion of participants having mild non-progressive disease. Well validated prognostic factors in PsA can identify these Participants including number of active joints, systemic inflammation levels, radiographic damage and functional ability at presentation. There is little research addressing outcomes and treatment options for mild disease., Psoriatic arthritis causes inflammation in and around the joints. It usually affects people who already have psoriasis, a skin condition that causes a red, scaly rash., Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
2018-004205-12: Methylprednisolone injection in treatment of birch pollen induced allergic rhinitis |
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| Not yet recruiting | 4 | 60 | Europe | Depo-medrol, Injection, Depo-Medrol® Injektionsvätska, suspension 40 mg/ml | Region Skåne, Region Skåne | Seasonal birch pollen induced allergic rhinitis, Pollen allergy, Body processes [G] - Circulatory and Respiratory Physiological Phenomena [G09] | | | | |
NCT03232749: Predicting Response to Intra-Articular Corticosteroid Injection in Patients With Osteoarthritis of the Glenohumeral Joint |
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| Terminated | 4 | 25 | US | intraarticular corticosteroid injections (IACSI), corticosteroid injections, Methylprednisolone, Depo-medrol, Ultrasound | University of Florida | Osteoarthritis of the Glenohumeral Joint | 06/19 | 06/19 | | |
| Terminated | 4 | 18 | US | Ketorolac Tromethamine Injection, Ketorolac Tromethamine; NDC 63323-162-02; J Code J1885, Methylprednisolone Acetate Injection, DEPO-MEDROL; NDC 0009-3073-01; J Code J1030, Hylan G-F 20, Synvisc-One; NDC 58468-0090-03; J Code J7325 | UConn Health, Orthopedic Research and Education Foundation | Osteoarthritis | 07/19 | 07/19 | | |
NCT01923909: Intraarticular Platelet-rich Plasma Injections Versus Corticosteroid Injections in Primary Knee Osteoarthritis |
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| Withdrawn | 4 | 0 | RoW | Intra-articular platelet-rich plasma, Prp, Intra-articular corticosteroid injections, Depo Medrol | King Hamad University Hospital, Bahrain | Osteoarthritis | 12/19 | 12/19 | | |
NCT04017741: A Study Investigating the Efficacy of GON Blocks. |
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| Completed | 4 | 8 | Europe | Combined Depo-Medrone and Lidocaine, Methylprednisolone Acetate BP 40mg/mL:, Lidocaine Hydrochloride 2%:, Sodium Chloride 0.9% Inj, normal saline 0.9% | Barts & The London NHS Trust | Migraine, Chronic Migraine, Headache | 12/19 | 01/20 | | |
NCT03704584: Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone |
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| Terminated | 4 | 62 | US | Treatment Group: Corticosteroid injection, depo-medrol, kenalog, Control Group (corticosteroid alone), Methylprednisolone acetate injectable suspension, Treatment Group: Lidocaine, Xylocaine | Emory University | Tenosynovitis | 01/20 | 01/20 | | |
NCT02867904: Intra-Operative Corticosteroid Injection During Arthroscopic Shoulder Surgery |
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| Terminated | 4 | 12 | US | Methylprednisolone (40 mg depomedrol, 1ml, injection), Marcaine (4ml 0.5%, injection) | Peter Chang | Arthroscopic Shoulder Surgery, Intra-articular Debridement, Subacromial Decompression, Acromioplasty, Acromioclavicular Joint Resection | 04/20 | 04/20 | | |
2020-002285-14: Effectiveness of corticosteroid injection in treatment of trigger fingers: a double blinded randomized clinical trial |
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| Not yet recruiting | 4 | 300 | Europe | depo-medrol, Kenacort, Kenacort-40, 8719497000913, Injection, Concentrate for solution for injection, Solution for injection, - Depo-Medrol: ATC code H02AB04 – Methylprednisolone: RVG code 00605, Kenacort-10 H02AB08 - Triamcinolone acetonide RVG code 01591, Kenacort-40 H02AB08 - Triamcinolone acetonide RVG code 05341 | JEROEN BOSCH HOSPITAL, Jeroen Bosch Hospital | Trigger finger (stenosing tenosynovitis) is one of the most common conditions seen by hand surgeons,Although not a severe disease, trigger fingers give disabling complaints in performance of work and ADL activities. The triggering is caused by a size mismatch between the first annular pulley (A1) and the corresponding flexor tendon sheath, but the precise etiology still remains unclear.2-4 Most often, trigger fingers do not resolve spontaneously and need some kind of treatment., A triggerfinger is a disease of the flexor tendon tunnel. It is too narrow due irritation that causes difficulty of the tendon to move in the tunnel., Diseases [C] - Musculoskeletal Diseases [C05] | | | | |
| Completed | 4 | 1 | Europe | Methotrexate, methotrexate sodium, Sulfasalazine, sulfasalazine pill, Leflunomide, leflunomide pill, Methylprednisolone, methylprednisolone acetate, Triamcinolone, triamcinolone acetonide | University of Oxford, National Institute for Health Research, United Kingdom | Psoriatic Arthritis | 07/20 | 07/20 | | |
NCT04622917: Methylprednisolone Injections Treating Birch Pollen Induced Allergic Rhinitis. |
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| Completed | 4 | 44 | Europe | MethylPREDNISolone 40 Mg/mL Injectable Suspension, Depo-Medrol, NaCl 9 MG/ML Injectable Solution, Sodium Chloride | Karolinska Institutet | Rhinitis, Allergic, Seasonal, Hay Fever, Pollen Allergy, Allergic Rhinitis | 06/22 | 05/23 | | |
NCT03973177: Phenol Neurolysis of Genicular Nerves for Chronic Knee Pain |
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| Withdrawn | 4 | 0 | NA | Phenol Injection, Phenol, Methylprednisolone Injection, Methylprednisolone acetate | Northwestern University | Pain, Chronic | 07/22 | 03/23 | | |
| Completed | 4 | 421 | US | Methylprednisolone (MPA), depomedrol, Triamcinolone Acetonide (TA), kenalog | Campbell Clinic | Shoulder Pain | 08/22 | 09/22 | | |
NCT04757740: Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint Dysfunction |
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| Completed | 4 | 94 | RoW | intra-articular Platelet rich fibrin and lidocaine, Platelet rich fibrin Group, methylprednisolone acetate and lidocaine, Steroid group | Fayoum University Hospital | Low Back Pain | 09/22 | 03/23 | | |
NCT06268704: Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection |
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| Recruiting | 4 | 230 | US | Dexamethasone, Ozurdex, Maxidex, DexPak, Methylprednisolone, Solu-medrol, Depo-Medrol, Medrol, 2% Lidocaine HCl Injection, Lignocaine, Xylocaine | University of New Mexico | Sacroiliac Joint Dysfunction, Sacro-Iliac Spondylosis | 01/25 | 05/25 | | |
NCT02283996: Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment |
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| Recruiting | 4 | 260 | US | Physical Therapy, Depot Methylprednisolone, Depo Medrol | Massachusetts General Hospital | Adhesive Capsulitis, Frozen Shoulder, Shoulder Frozen | 12/26 | 12/27 | | |
NCT04177433: The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint |
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| Recruiting | 4 | 90 | Canada | Depo-Medrol Injectable Product, Saline | University of Alberta | Osteoarthritis of the Carpometacarpal Joint, Thumb Osteoarthritis | 12/24 | 12/24 | | |
NCT03661645: Post-operative Methylprednisolone Taper Course for Orthopedic Surgery |
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| Enrolling by invitation | 4 | 1000 | US | 10 mg IV dexamethasone & 6 day oral methylprednisolone taper, Medrol, Depo-Medrol, Solu-Medrol, A-Methapred, Decadron, Dexasone, Diodex, Hexadrol, Maxidex, 10 mg IV dexamethasone | Emory University | Orthopedic Surgeries | 01/25 | 01/25 | | |
| Recruiting | 4 | 80 | US | Depo-Medrol, Gel-Flow NT | Hardeep Singh, Society for Minimally Invasive Spine Surgery | Muscle Weakness, Pain, Postoperative, Paresthesia, Pain, Muscle | 08/25 | 05/27 | | |
