Rizaben (tranilast) / Kissei, Nuon Therapeutics |
ChiCTR2000030002: Clinical study of novel NLRP Inflammasome inhibitor (Tranilast) in the treatment of novel coronavirus pneumonia (COVID-19) |
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| Recruiting | 4 | 60 | China | conventional therapy ;conventional therapy and Tranilast | The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital); The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital), Anhui Development and Reform Commission | Novel Coronavirus Pneumonia (COVID-19) | | | | |
NCT05130892: Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI |
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| Completed | 4 | 132 | RoW | Colchicine, Tranilast, Oridonin | Wuhan Union Hospital, China | NLRP3, hsCRP, Percutaneous Coronary Intervention | 02/23 | 02/23 | | |
NCT06307288: Efficacy and Safety of Tranilast Combined With Minocycline in the Treatment of Rosacea |
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| Enrolling by invitation | 4 | 45 | RoW | minocycline, tranilast | Second Affiliated Hospital of Xi'an Jiaotong University | Rosacea | 06/24 | 06/24 | | |
NCT03923140: A Clinical Study of Tranilast in the Treatment of Cryopyrin-Associated Periodic Syndrome (CAPS) |
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| Recruiting | 2 | 71 | RoW | Tranilast, Rizaben | Peking Union Medical College Hospital | Cryopyrin-Associated Periodic Syndromes | 04/24 | 10/24 | | |
NCT05626829: Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal Carcinoma |
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| Recruiting | 2 | 18 | RoW | Tranilast | Jian Guan | Nasopharyngeal Carcinoma, Recurrent Cancer | 07/24 | 11/24 | | |
ChiCTR1800015808: Pilot Clinical Study of Chemo-Cocktail (TTF) for Recurrent Glioblastoma |
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| Recruiting | 1 | 10 | | temmozoldmide+tranilast+fasudil | Huashan Hospital, Fudan University; Huashan Hospital, Fudan University, No | Recurrent Glioblastoma | | | | |
NCT03490708: A Clinical Study of Tranilast in the Treatment of Mucinoses |
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| Not yet recruiting | 1 | 56 | NA | Tranilast | The First Affiliated Hospital with Nanjing Medical University | Mucinoses | 06/22 | 12/22 | | |
ChiCTR1900028455: A single center, randomized, single blind, controlled trial for tranilast in the treatment of gout |
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| Not yet recruiting | N/A | 160 | | take one tranilast capsule (each containing 0.1g of tranilast), three times a day, take it after three meals, treatment for one week ;take 2 capsules of tranilast (0.1g of tranilast per capsule), 3 times / day, after three meals, treatment for 1 week ;Take 1 diclofenac capsule (each containing 50mg of diclofenac) twice a day, take it after breakfast and dinner, and treat for 1 week ;Take 1 colchicine tablet (each tablet contains 0.5mg colchicine), 3 times / day, take after three meals, treatment for 1 week | The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital); The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital), Researchers spontaneous | Gout | | | | |