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| Completed | 2 | | Europe | cisplatin, docetaxel, epirubicin hydrochloride, fluorouracil | Swiss Group for Clinical Cancer Research | Gastric Cancer | 07/03 | 07/03 | | |
NCT00375999: Docetaxel and Epirubicin in Advanced Gastric Cancer |
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| Completed | 2 | 34 | RoW | Docetaxel and epirubicin, taxotere, pharmorubicin | Yonsei University | Stomach Neoplasms | 12/06 | 12/06 | | |
NCT00058487: Epirubicin and Thalidomide in Treating Patients With Liver Cancer |
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| Completed | 2 | 12 | US | epirubicin hydrochloride, thalidomide | Dana-Farber Cancer Institute, National Cancer Institute (NCI) | Liver Cancer | | 01/07 | | |
| Completed | 2 | 72 | Europe | Matuzumab, EMD 72000, Epirubicin, Cisplatin, Capecitabine | Merck KGaA, Darmstadt, Germany | Esophageal Cancer, Gastric Cancer | 07/08 | 08/08 | | |
| Completed | 2 | 105 | Europe | capecitabine, XELODA, cisplatin, Cisplatino-TEVA, docetaxel, TAXOTERE, epirubicin hydrochloride, FARMARUBICINA, gemcitabine hydrochloride, GEMZAR | IRCCS San Raffaele | Pancreatic Cancer | 04/09 | 10/09 | | |
NCT00743964: Phase II Study of Epirubicin, Cisplatin and Capecitabine (ECX) Versus Cisplatin and Capecitabine (CX) for Advanced Gastric Cancer (AGC) |
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| Completed | 2 | 91 | RoW | Epirubicin, Cisplatin, capecitabine | Samsung Medical Center | Advanced Gastric Cancer | 10/09 | 10/09 | | |
NCT00820053: A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver Resection |
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| Completed | 2 | 450 | RoW | epirubicin and lipiodol, transarterial chemoembolization | Eastern Hepatobiliary Surgery Hospital | Hepatocellular Carcinoma | 12/09 | 12/10 | | |
NCT00220129: Neoadjuvant Epirubicin, Cisplatin and Capecitabine (ECX) Followed by Definitive Chemoradiation With/Without Surgery for Squamous Cell Carcinoma of the Oesophagus |
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| Completed | 2 | 16 | Europe | Epirubicin, Cisplatin, Capecitabine, Surgical Resection | Royal Marsden NHS Foundation Trust | Oesophageal Carcinoma | | | | |
NCT00220103: Pre-operative Epirubicin, Cisplatin, and Capecitabine in Patients With Newly Diagnosed Localised Oesophageal Adenocarcinoma |
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| Completed | 2 | 80 | Europe | epirubicin, capecitabine, cisplatin, Surgical resection | Royal Marsden NHS Foundation Trust | Adenocarcinoma of Oesophagus | | | | |
NCT00025441: Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors |
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| Completed | 2 | | Europe | dactinomycin, filgrastim, carboplatin, cyclophosphamide, doxorubicin hydrochloride, epirubicin hydrochloride, etoposide, ifosfamide, vincristine sulfate, peripheral blood stem cell transplantation, radiation therapy | Societe Internationale d'Oncologie Pediatrique, Children's Cancer and Leukaemia Group, Societe Francaise Oncologie Pediatrique | Ovarian Cancer, Sarcoma, Small Intestine Cancer | | 03/10 | | |
NCT00595972: Epirubicin Cisplatin and Fluorouracil (FU) Combined With Endostar in Patients With Advanced or Metastatic Gastric Cancer |
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| Completed | 2 | 25 | RoW | ECF-endostar, treatment group | Fudan University | Gastric Cancer | 12/10 | 12/10 | | |
| Completed | 2 | 28 | Europe | Radioembolisation (SIR-Spheres® microspheres), Transarterial Chemoembolisation | Sirtex Medical | Hepatocellular Carcinoma | 06/11 | 06/11 | | |
NCT00601705: Epirubicin, Oxaliplatin and Fluorouracil (EOF) in Cancer of the Esophagus, Gastroesophageal Junction, or Stomach |
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| Completed | 2 | 61 | US | cisplatin, epirubicin hydrochloride, fluorouracil, oxaliplatin, adjuvant therapy, neoadjuvant therapy | Case Comprehensive Cancer Center, National Cancer Institute (NCI) | Esophageal Cancer, Gastric Cancer | 03/12 | 01/15 | | |
NCT00767377: Continuous Infusion of FU Combined With Epirubicin and Oxaliplatin in Patients With A/MGC |
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| Completed | 2 | 163 | RoW | EOF5, treatment group | Fudan University | Gastric Cancer | 07/12 | 03/13 | | |
NCT01710592 / 2006-003332-29: A Phase II Trial of Epirubicin, Oxaliplatin and Capecitabine (EOX) Versus Docetaxel and Oxaliplatin (ElTax) in the Treatment of Advanced Gastro-oesophageal Cancer |
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| Completed | 2 | 35 | Europe | Epirubicin, Oxaliplatin, Capecitabine, Docetaxel | Cancer Trials Ireland | Gastro Oesophageal Cancer | 12/12 | | | |
NCT01123473 / 2009-011580-36: Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without Lapatinib Ditosylate as First-Line Therapy in Treating Patients With Stomach Cancer or Gastroesophageal Junction Cancer |
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| Terminated | 2 | 29 | Europe | capecitabine, cisplatin, epirubicin hydrochloride, fluorouracil, lapatinib ditosylate | European Organisation for Research and Treatment of Cancer - EORTC | Adenocarcinoma of the Gastroesophageal Junction, Gastric Cancer | 08/13 | 09/14 | | |
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| Terminated | 2 | 60 | Europe | capecitabine, XELODA, cisplatin, cisplatino TEVA, epirubicin, farmorubicina, gemcitabine, GEMZAR, metformin, glucophage | IRCCS San Raffaele | Pancreatic Cancer | 12/14 | 04/15 | | |
NCT00737438: Pre-operative Chemotherapy Plus Bevacizumab With Early Salvage Therapy Based on PET Assessment of Response in Patients With Locally Advanced But Resectable Gastric and GEJ Adenocarcinoma |
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| Completed | 2 | 22 | US | epirubicin, cisplatin, capecitabine, bevacizumab, docetaxel and irinotecan, Patients who have a poor PET response to cycle 1 of ECX plus bevacizumab, (eg. < 35% FDG reduction on the week 3 PET scan compared with baseline), will be switched to salvage therapy of docetaxel and irinotecan (DI)., This treatment will be administered on week 1 and 2 of a 3, week cycle for 2 cycles. Patients will receive bevacizumab for the 1st cycle, of salvage docetaxel/irinotecan only. There is again a planned 10-12 week time, interval (eg. 70-84 days) between the last bevacizumab treatment and surgery. | Memorial Sloan Kettering Cancer Center, Genentech, Inc., Weill Medical College of Cornell University | Esophageal Cancer, Gastric Cancer | 02/15 | 02/15 | | |
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NCT01830270: Preoperative Dose-dense Chemotherapy With Weekly Cisplatin, Epirubicin and Paclitaxel to Treat Patients With Locally Gastric Cancer |
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| Terminated | 2 | 30 | Europe | Epirubicin, Cisplatin, Paclitaxel, gastric surgery | Centre Hospitalier Universitaire de Besancon | Stomach Neoplasms, Oesophageal Junction Cancer, Lower Oesophagus Cancer | 04/15 | 07/16 | | |
NCT01624025: A Comparative Study of Salvage Treatment With Combination of Docetaxel and Epirubicin |
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| Completed | 2 | 22 | RoW | Docetaxel 60 mg/m2, epirubicin 60 mg/m2, q3wks | Yonsei University | Metastatic Advanced Gastric Cancer | 09/15 | 02/16 | | |
| Terminated | 2 | 21 | Europe | Omegaven, Omega-3 fish oil | University Hospitals, Leicester | Esophageal Neoplasm, Gastric Neoplasm | 12/15 | 12/15 | | |
| Completed | 2 | 171 | Europe | Epirubicin, Cisplatin, Capecitabine, Panitumumab, Xeloda®, Epirubicin, Cisplatin, Capecitabine, Vectibix®, Xeloda® | AIO-Studien-gGmbH, Amgen, WiSP Wissenschaftlicher Service Pharma GmbH | Stomach Neoplasms, Gastroesophageal Junction Neoplasms | 08/16 | 08/17 | | |
| Completed | 2 | 98 | Europe | capecitabine, XELODA, cisplatin, cisplatino TEVA, epirubicin, farmorubicina, gemcitabine, GEMZAR | IRCCS San Raffaele | Pancreatic Cancer | 04/17 | 08/17 | | |
| Completed | 1b/2 | 130 | US, Canada, Europe, RoW | Capecitabine, Xeloda, Epirubicin, AMG 102, Cisplatin, Placebo | Amgen | Esophagogastric Junction Adenocarcinoma, Gastric Cancer, Esophageal Cancer | 11/10 | 06/13 | | |
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NCT00021047: Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor |
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| Completed | 1/2 | | US | capecitabine, carboplatin, epirubicin hydrochloride | National Institutes of Health Clinical Center (CC), National Cancer Institute (NCI) | Esophageal Cancer, Extrahepatic Bile Duct Cancer, Gastric Cancer, Head and Neck Cancer, Liver Cancer, Unspecified Adult Solid Tumor, Protocol Specific | | 06/04 | | |
NCT00057980: Epirubicin and Celecoxib in Treating Patients With Hepatocellular Carcinoma |
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| Completed | 1/2 | 8 | US | celecoxib, epirubicin hydrochloride | Northwestern University, National Cancer Institute (NCI) | Liver Cancer | 02/07 | 02/07 | | |
NCT00130936: Study of Epirubicin (Pharmorubicin®), Carboplatin (Paraplatin®) and Capecitabine (Xeloda®) (ECC) in the Treatment of Unresectable Locally Advanced or Metastatic Gastric/Gastroesophageal Junction Cancer With Pharmacogenetic Correlates |
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| Terminated | 1/2 | 50 | Canada | Epirubicin, Carboplatin, Capecitabine | AHS Cancer Control Alberta | Gastric Cancer, Esophageal Cancer, Tumors | | 11/07 | | |
EOXP, NCT00667420: Perioperative Panitumumab and Epirubicin, Oxaliplatin and Xeloda (EOX) in Patients With Gastroesophageal Adenocarcinoma |
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| Terminated | 1/2 | 17 | US | panitumumab, epirubicin, oxaliplatin, xeloda | Massachusetts General Hospital | Esophageal Adenocarcinoma, Gastric Adenocarcinoma | 06/11 | 06/14 | | |
