Neuroectodermal Tumors  >>  humanised dinutuximab (Hu14.18K322A)  >>  Phase 1
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3 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
humanised dinutuximab (Hu14.18K322A) / Essential Pharma
NCT00743496: A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and Melanoma

Completed
1
50
US
Anti-GD2 antibody
St. Jude Children's Research Hospital, Evan T.J. Dunbar Neuroblastoma Foundation, Duke University, University of Wisconsin, Madison, University Children's Hospital Tuebingen, Children's Hospital Los Angeles
Neuroblastoma, Melanoma, Osteosarcoma, Ewing Sarcoma
04/14
04/14
NCT01576692: Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma

Completed
1
34
US
Humanized anti-GD2 antibody, Hu14.18K322A monoclonal antibody, Chemotherapy, Cytoxan, Hycamtin, Temodar, Camptosar, Paraplatin, Ifex, VP-16, Vepesid, Cytokines, IL-2, Aldesleukin, Proleukin, Sargramostim, Leukine, Natural killer cells, NK cells, CliniMACS, Cell Selection System
St. Jude Children's Research Hospital, CURE Childhood Cancer, Inc.
Neuroblastoma
10/14
10/18
NCT02130869: A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

Completed
1
8
US
CD133+ selected autologous stem cell infusion, Natural killer (NK) cell infusion, IL-2, Interleukin-2, Aldesleukin, Proleukin(R), hu14.18K322A, anti-GD2 antibody, Hu14.18K322MAB, Busulfan, Busulfex(R), Myleran(R), Melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, GM-CSF, Sargramostim, Leukine(R), Bendamustine, Treanda®, Bendamustine hydrochloride, Etoposide, VP-16, Vepesid(R), Cytarabine, ARA-C, Carboplatin, Inorganic heavy metal coordination complex, Haploidentical natural killer cell infusion, NK cell infusion, G-CSF, Filgrastim, Neupogen(R), Etoposide phosphate, Etopophos(R), CliniMACS, Cell Selection System
St. Jude Children's Research Hospital
Neuroblastoma, Lymphoma, High-risk Tumor
12/17
12/17

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