| risperidone / Generic mfg. |
NCT00158028: Risperidone in the Treatment of Psychotic-like and Deficit Symptoms of Schizotypal Personality Disorder |
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| Completed | N/A | 25 | US | Risperidone, Placebo | Icahn School of Medicine at Mount Sinai, Janssen Pharmaceutica | Schizotypal Personality Disorder | 12/01 | 12/01 | | |
NCT00515489: Study on the Safety and Effectiveness of Risperidone Treatment of Acute Psychotic Patients |
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| Terminated | N/A | 1882 | Europe | Risperidone | Janssen-Cilag, S.A. | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders | | 08/02 | | |
NCT00511628: Study on the Safety of Risperidone on Obese or Overweight Patients With Schizophrenia |
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| Terminated | N/A | 1717 | Europe | Risperidone | Janssen-Cilag, S.A. | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder | | 01/03 | | |
NCT00457106: A Single-Blind Trial of Risperidone vs. Paroxetine for Treatment of Panic Attacks |
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| Completed | N/A | 90 | US | Paroxetine, Risperidone | Beth Israel Medical Center | Major Depression With Panic Attacks, Panic Disorder | 06/03 | 06/03 | | |
NCT00203775: Haloperidol vs. Risperidone in the Treatment of Aggression in Psychotic Inmates |
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| Terminated | N/A | | US | risperidone | University of Connecticut, Janssen Pharmaceutica N.V., Belgium | Psychosis, Aggression | | 04/04 | | |
| Completed | N/A | 450 | US | Olanzapine, Quetiapine, Risperidone, Citalopram | National Institute of Mental Health (NIMH) | Alzheimer's Disease | | 10/04 | | |
NCT00018291: Specific Interventions for Agitation in Alzheimer's Disease |
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| Completed | N/A | | US | Risperidone, Gabapentin | US Department of Veterans Affairs | Alzheimer's Disease, Dementia | | 01/05 | | |
NCT01234454: Atypical Antipsychotic Treatment Effect On Brain Function In Schizophrenia Measured By FMRI |
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| Completed | N/A | 34 | US | Risperidone, risperidol, risperidal, Olanzapine, Zydis, Zyprexa | University of North Carolina, Chapel Hill | Schizophrenia | 06/05 | 12/07 | | |
NCT00012558: Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) |
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| Completed | N/A | 5000 | US | lithium, valproate, bupropion, paroxetine, lamotrigine, risperidone, inositol, tranylcypromine, Cognitive Behavioral Therapy, Family-focused Therapy, Interpersonal and Social Rhythms Therapy | National Institute of Mental Health (NIMH) | Bipolar Disorder | | 09/05 | | |
NCT00197483: Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia |
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| Suspended | N/A | 20 | Japan | Pergolide (drug) | Hamamatsu University | Schizophrenia, Negative Symptoms, Cognitive Impairments | | | | |
NCT00174200: Study To Assess Differential Sensitivity Of 2 Spatial Working Memory Tests In Schizophrenics Treated With Risperidone |
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| Completed | N/A | 20 | Canada, RoW | Risperidone 2 mg | Pfizer | Schizophrenia, Psychotic Disorders | | 05/06 | | |
NCT00222495: A Comparative Study of New Medications for Psychosis in Adolescents |
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| Completed | N/A | 30 | US | quetiapine, olanzapine, risperidone | University of Minnesota, AstraZeneca, Jensen, Jonathan B., M.D. | Psychotic Disorders, Schizophrenia, Schizophreniform Disorders, Schizoaffective Disorders | | 08/06 | | |
| Completed | N/A | 120 | US | Risperidone, Olanzapine | Washington University School of Medicine, Janssen, LP | Schizophrenia, Type 2 Diabetes Mellitus | 10/06 | 10/06 | | |
NCT00006195: Glucose Regulation During Risperidone and Olanzapine Treatment |
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| Unknown status | N/A | | US | risperidone, olanzapine | National Center for Research Resources (NCRR), Janssen, LP, Washington University School of Medicine | Schizophrenia | | | | |
NCT00227123: A Randomized Control Trial Comparing Quetiapine to Risperidone in Bipolar Disorder With Stimulant Dependence |
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| Completed | N/A | 96 | US | quetiapine, risperidone, Seroquel, Risperdal | University of Texas Southwestern Medical Center, Stanley Medical Research Institute, University of North Texas Health Science Center | Bipolar Disorder, Cocaine Dependence, Methamphetamine Dependence | | 11/06 | | |
NCT00287027: Family Perspectives:Treatment of Psychiatric Illnesses With Atypical Long Acting Injectable Antipsychotic Medication |
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| Terminated | N/A | 60 | US | Risperdal Long Acting Injectable Antipsychotic Medication | National Alliance on Mental Illness New Hampshire, Janssen Medical Affairs | Psychotic Disorders | | 12/06 | | |
| Completed | N/A | 2006 | RoW | Olanzapine, Risperidone, Haloperidol | Central Institute of Psychiatry, Ranchi, India | Metabolic Syndrome, Diabetes, Obesity | | 12/06 | | |
| Completed | N/A | 36 | Europe | quetiapine or olanzapine or risperidone or aripiprazole | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | Schizophrenia | | 02/07 | | |
NCT00169988: Antidepressant and Antipsychotic to Treat Attenuated Positive and Negative Symptoms |
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| Completed | N/A | 8 | US | risperidone, sertraline-primary | Northwell Health, Stanley Medical Research Institute, Janssen Pharmaceutica N.V., Belgium, Pfizer | Prodromal Schizophrenia, Psychotic Disorders | | 04/07 | | |
NCT00179062: Effects of Risperidone and Olanzapine on Patients With Schizophrenia, Schizoaffective Disorder, Major Depression or Bipolar Disorder |
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| Completed | N/A | 300 | US | olanzapine versus risperidone | Vanderbilt University | Schizophrenia, Schizoaffective Disorder, Depressive Disorder, Major, Bipolar Disorder | 06/07 | 06/07 | | |
NCT00080145: RUPP PI PDD: Drug and Behavioral Therapy for Children With Pervasive Developmental Disorders |
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| Completed | N/A | 124 | US | Risperidone, Behavior Therapy | Yale University, National Institute of Mental Health (NIMH) | Child Development Disorders, Pervasive | 09/07 | 09/07 | | |
NCT00644852: Medical Chart Review of Patients on Long-term Treatment With Long-acting Injectable Risperidone |
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| Completed | N/A | 342 | RoW | Retrospective chart review study | Johnson & Johnson Taiwan Ltd | Schizophrenia, Schizoaffective Disorder | 09/07 | 09/07 | | |
e-STAR, NCT00774085: An Observational Study to Assess Treatment & Outcomes Data in Patients Receiving Long-Acting Injectable Risperidone |
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| Completed | N/A | 408 | Europe | No intervention was given | Janssen Cilag N.V./S.A. | Schizophrenia | 12/07 | 12/07 | | |
NCT00686140: A Double-blind and Randomized Trial of Celecoxib Added to Risperidone in Treatment-naive First-episode Schizophrenia |
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| Completed | N/A | 200 | RoW | celecoxib, Celebrex(R), Placebo | Beijing HuiLongGuan Hospital, Stanley Medical Research Institute | Schizophrenia | 12/07 | 03/08 | | |
NCT00225498: Neurocognitive Effects of Ziprasidone: Relationship to Working Memory and Dopamine Blockade |
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| Completed | N/A | 35 | US | ziprasidone vs risperidone or olanzapine, Geodon vs Risperdal or Zyprexa | Northwell Health | Schizophrenia | 10/08 | 10/08 | | |
| Completed | N/A | 96 | US | risperidone, Risperdal, olanzapine, Zyprexa, quetiapine, Seroquel, ziprasidone, Geodon | Washington University School of Medicine, National Institute of Mental Health (NIMH) | Schizophrenia, Schizoaffective Disorder, Type 2 Diabetes Mellitus, Hyperglycemia | 12/08 | 12/08 | | |
| Completed | N/A | 100 | Canada | 2 antipsychotic medications (combinations of olanzapine, risperidone, clozapine, seroquel, haldol, perphenazine), main antipsychotic medication and placebo | Centre for Addiction and Mental Health, Canadian Psychiatric Research Foundation | Schizophrenia | 12/08 | | | |
NCT00633802: Low-Dose Risperidone Treatment for Subjects Suffering From Borderline Personality Disorder |
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| Unknown status | N/A | 30 | RoW | Risperidone | Tel-Aviv Sourasky Medical Center | Borderlone Personality Disorder | 04/09 | | | |
NCT01185418: Evaluation of Negative Symptoms and Cognitive Function After Administration of Antipsychotics in Healthy Volunteer |
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| Completed | N/A | 80 | RoW | risperidone, aripiprazole, haloperidol, amisulpride, lactose | Chonbuk National University Hospital | Normal Volunteers | 07/09 | 07/09 | | |
NCT00312598: Body Mass Index (BMI) and Metabolic Changes Following Switch to Aripiprazole From Olanzapine, Risperidone and Quetiapine |
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| Completed | N/A | 30 | US | Aripiprazole, Abilify | University of North Carolina, Chapel Hill, Bristol-Myers Squibb | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Mood Disorders | 04/10 | 04/10 | | |
NCT01043250: Effects of Atypical Antipsychotics on Appetite and Eating Behavior of Schizophrenia Patients |
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| Completed | N/A | 81 | RoW | | Samsung Medical Center, Ministry of Health & Welfare, Korea, Korea Otsuka Pharmaceutical Co., Ltd. | Schizophrenia, Schizoaffective Disorder | 04/10 | 12/10 | | |
| Completed | N/A | 1 | US | risperidone, Actigraphic measurements | Child Psychopharmacology Institute | Sleep Disorders, Circadian Rhythm, Insomnia, Psychomotor Agitation | 07/10 | 08/10 | | |
NCT00206960: Dopaminergic, Functional, Structural, and Cognitive Disturbances in First-episode Schizophrenia |
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| Completed | N/A | 56 | Europe | zuclopenthixol, Cisordinol, risperidone, Risperdal | Birte Glenthoj, University of Copenhagen, Glostrup University Hospital, Copenhagen, Rigshospitalet, Denmark, Hvidovre University Hospital, The Danish Medical Research Council, Copenhagen Hospital Corporation, Janssen-Cilag Ltd., The Novo Nordic Foundation | Schizophrenia | 09/10 | 09/10 | | |
PAMS, NCT00746252: Side Effect Study of Antipsychotic Medicines to Treat Childhood Bipolar Disorder |
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| Terminated | N/A | 5 | US | risperidone, Brand name: Risperdal, aripiprazole, Brand name: Abilify | University of Maryland, Baltimore | Bipolar Disorder | 10/10 | 10/10 | | |
NCT00573287: First Episode Schizophrenia and Cannabis-Related Disorder Study |
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| Completed | N/A | 14 | US | clozapine, Clozaril, risperidone, Risperdal | Dartmouth-Hitchcock Medical Center, National Institute of Mental Health (NIMH) | Cannabis-Related Disorder, Substance-Related Disorders, Schizophrenia, Psychotic Disorders | 12/10 | 12/11 | | |
NCT01057849: Standard Comprehensive Intervention to Treat First-episode Schizophrenia |
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| Unknown status | N/A | 600 | RoW | risperidone, olanzapine, Aripiprazole | Peking University, Ministry of Science and Technology of the People´s Republic of China | Schizophrenia | 03/11 | | | |
NCT00783783: CYP2D6 Pharmacogenetics in Risperidone-Treated Children |
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| Completed | N/A | 47 | US | | Children's Hospital Medical Center, Cincinnati, Ohio State University, Rainbow Babies and Children's Hospital | Psychiatric Disorders, Neurodevelopmental Disorders | 06/11 | 06/11 | | |
ChiCTR-TRC-13003145: Anti-toxoplasma Chinese Medicine as an Adjunct Therapy in Schizophrenia with seropositivity to T. gondii |
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| Completed | N/A | 100 | | artemether and risperidone ;Placebo and risperidone | Renmin Hospital of Wuhan University; Renmin Hospital of Wuhan University, the Stanley Medical Research Institute （USA） | schizophrenia | | | | |
NCT01026285: InORS - International Observational Registry on Schizophrenia With Injectable Risperidone and Oral Antipsychotics |
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| Completed | N/A | 1085 | Europe, RoW | Risperidone Long-Acting injectable or oral antipsychotics | Janssen-Cilag International NV | Schizophrenia | 03/12 | 03/12 | | |
NCT00629252: The Effect of Sertindole on Sensory Gating and Cognition in Schizophrenic Patients |
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| Terminated | N/A | 14 | Europe | Sertindole, Risperidone | University of Zurich, University Hospital of Psychiatry, Department Neuropsychopharmacology and Brain Imaging, H. Lundbeck A/S | Schizophrenia | 08/12 | 08/12 | | |
NCT02582736: Antipsychotics and Risk of Hyperglycemic Emergencies |
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| Completed | N/A | 725489 | Canada | Olanzapine, atypical antipsychotic, Risperidone, atypical antipsychotics (other), Clozapine, Quetiapine, Ziprasidone, Paliperidone, Aripiprazole, typical antipsychotics, Chlormezanone, Chlorpromazine, Chlorprothixene, Flupenthixol, Fluphenazine, Fluspirilene, Haloperidol, Levomepromazine, Loxapine, Mesoridazine, Methotrimeprazine, Perphenazine, Pimozide, Pipotiazine, Tetrabenazine, Thiopropazate, Thioproperazine, Thioridazine, Thiothixene, Trifluoperazine, Zuclopenthixol | Canadian Network for Observational Drug Effect Studies, CNODES, Drug Safety and Effectiveness Network, Canada, Canadian Institutes of Health Research (CIHR) | Psychotic Disorders, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Diabetes Mellitus, Type 2 | 12/12 | 12/12 | | |
| Completed | N/A | 124 | RoW | Ginkgo biloba extract, EGb761, Placebo | Beijing HuiLongGuan Hospital | Schizophrenia | 06/13 | 08/13 | | |
NCT01770600: Impulsivity and Thought Process Disorder in Patients With Active Suicidal Ideation and Depression |
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| Withdrawn | N/A | 0 | US | placebo, Riperidone, risperdal | University of Alabama at Birmingham | Impulsivity, Active Suicidal Ideation, Depression | 09/13 | | | |
NCT01181960: Research and Evaluation of Antipsychotic Treatment in Community Behavioral Health Organizations |
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| Completed | N/A | 1066 | US | Risperidone long acting injectable - New Starts, Risperidone long acting injectable - Continuous Users, Paliperidone Palmitate -New and Continuous Users, Other Antipsychotics - New Starts | Janssen Scientific Affairs, LLC | Schizophrenia, Bipolar Disorder | 11/13 | 11/13 | | |
NCT02013232: Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia |
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| Unknown status | N/A | 120 | RoW | Aripiprazole | Beijing HuiLongGuan Hospital | Schizophrenia | 01/14 | 02/14 | | |
ChiCTR-TRC-14004186: Research of the variance on patients with schizophrenia treated with aripiprazole on hyperprolactinemia induced by risperidone or paliperidone |
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| Completed | N/A | 60 | | adjunctive with 5mg aripiprazole ;single risperidone treatment | Shanghai Mental Health Center; Level of the institution：, project of Shanghai Mental Health Center | Schizophrenia | | | | |
NCT02192723: A Randomized Double-blind Trial With 6 Antipsychotic Drugs for Schizophrenia |
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| Completed | N/A | 550 | RoW | Typical antipsychotic, Haldol and Trilafon, Risperidone, Risperdal, Olanzapine, Zyprexa, Quetiapine, Seroquel, Aripiprazole, Abilify, Ziprasidone, Geodon | Beijing HuiLongGuan Hospital | Schizophrenia | 06/14 | 06/14 | | |
NCT01896349: Interpersonal Psychotherapy for Treatment Resistant Depression |
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| Unknown status | N/A | 74 | RoW | IPT+ antidepressant drugs, Interpersonal Psychotherapy, Antidepressant drugs, fluoxetine, sertraline, paroxetine, Citalopram, escitalopram, fluvoxamine, Venlafaxine, Duloxetine, Bupropion, Lithium, Risperidone, tranylcypromine, Imipramine, amitriptyline, Clomipramine, nortriptyline, trazodone, Mirtazapine, sulpiride | Hospital de Clinicas de Porto Alegre | Treatment Resistant Depression | 08/14 | 11/14 | | |
| Unknown status | N/A | 300 | RoW | risperidone, Risperidol, olanzapine, olanzapine tablets, Quetiapine, quetiapine tablets, Aripiprazole, Aripiprazole tablets | Central South University | Psychotic Disorders | 12/14 | 12/14 | | |
NCT02221635: Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Schizoaffective |
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| Unknown status | N/A | 540 | RoW | rTMS + risperidone, Risperidone | Xijing Hospital, The No.3 hospital of PLA, The No.91 hospital of PLA, No. 102 Hospital of Chinese People's Liberation Army | Schizoaffective Disorder | 12/14 | 01/15 | | |
ChiCTR-IOR-15006278: Adjunctive aripiprazole treatment for risperidone-induced hyperprolactinemia: an 8-week randomized, open-label, comparative clinical trial |
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| Completed | N/A | 113 | | no additional treatment ;adjunctive treatment with aripiprazole 10mg/day | The Second Affiliated Hospital/ Xinxiang Medical University; The Second Affiliated Hospital/ Xinxiang Medical University, Funding for this study was provided by the National Natural Science Foundation of China (No.30971058; No.81071090, 81371472), the Natural Science Foundation of Henan (No.102300413208) | Schizophrenia | | | | |
NCT01698216: Switching From Consta® to Sustenna® in Patients With Schizophrenia |
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| Completed | N/A | 50 | RoW | | Seoul National University Hospital | Schizophrenia | 05/15 | 05/15 | | |
| Completed | N/A | 91 | RoW | Guideline treatment (Risperidone, administered orally), Atypical antipsychotic, "Psychosocial treatment", "Psychoeducation", "Social Skills", "Healthy Life style", "Exercise in group", Treatment as Usual (any other antipsychotic), Any other antipsychotic assigned by clinician | Hospital Psiquiatrico Infantil Dr. Juan N. Navarro, Mexico | Schizophrenia | 06/15 | 07/15 | | |
NCT00716755: Minimizing Doses of Antipsychotic Medication in Older Patients With Schizophrenia. |
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| Completed | N/A | 45 | Canada | Risperidone/Olanzapine and PET scans, Risperidal, Zyprexa | Centre for Addiction and Mental Health | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Delusional Disorder, Psychotic Disorder | 08/15 | 08/15 | | |
| Completed | N/A | 50 | US | Risperidone, Risperdal, Omega-3 capsules, Omega-3, Placebo, Placebo capsules | Delbert Robinson, National Institute of Mental Health (NIMH), National Alliance for Research on Schizophrenia and Depression | Schizophrenia, Schizophreniform Disorder, Schizoaffective Disorder, Bipolar Disorder, Psychosis NOS | 09/15 | 09/15 | | |
NCT01739127: Comparison of Aripiprazole Versus Higher Metabolic Risk Antipsychotic Drugs on Adiposity Using MRI |
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| Completed | N/A | 83 | Canada | Aripiprazole, ABILIFY, Risperidone/Quetiapine, Risperdal, Apo-risperidone, Seroquel, Apo-quetiapine | University of British Columbia, Bristol-Myers Squibb | Psychotic Disorders, Bipolar Disorder, Metabolic Syndrome X | 02/16 | 02/16 | | |
| Completed | N/A | 37 | US | | Massachusetts General Hospital, Novartis Pharmaceuticals | Schizophrenia, Serious Mental Illness, Metabolic Syndrome, Insulin Resistance, Glucose Metabolism | 05/16 | 05/16 | | |
CARB, NCT02334904: Comparison of Aripiprazole Versus Risperidone on Brain Morphology Using MRI |
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| Unknown status | N/A | 60 | Canada | Aripiprazole, Abilify, Risperidone | University of British Columbia, Vancouver Coastal Health | First-Episode Psychosis, Bipolar Disorder | 06/16 | 06/16 | | |
NCT01931059: Acute D2 Receptor Blockade Induced Neuronal Network Changes in Human Volunteers |
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| Completed | N/A | 11 | US | Risperidone, Placebo | Northwell Health | Imaging of the Brain and Antipsychotics, Neuronal Network Changes | 07/16 | 07/16 | | |
ChiCTR-IOR-14005304: A randomized, 13-week study assessing the efficacy and safety of paliperidone palmitate and olanzapine in first-episode schizophrenic patients |
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| Recruiting | N/A | 100 | | Palm trees risperidone long-acting injection Paley ;Control | First Affiliated Hospital, College of Medicine, Zhejiang University; First Affiliated Hospital, College of Medicine, Zh, National Natural Science Foundation (81301158) | Schizophrenic | | | | |
NCT02423096: Neuroendocrine and Metabolite Substrates in Schizophrenia |
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| Unknown status | N/A | 200 | RoW | Risperidone, Haloperidol, Sulpiride, Olanzapine, Quetiapine | Chang Gung Memorial Hospital | Schizophrenia | 12/16 | 12/16 | | |
NCT02661347: Transcranial Direct Current Stimulation for Hallucinations in First-Episode Schizophrenia |
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| Withdrawn | N/A | 0 | US | Risperidone, tDCS | Northwell Health | Schizophrenia, Schizophreniform, Schizoaffective Disorder, Psychosis Not Otherwise Specified (NOS) | 12/16 | 12/16 | | |
NCT03019887: Correlation Between Cognitive Function and Relapse of Schizophrenia Regarding Dose Reduction |
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| Completed | N/A | 139 | NA | reduction of risperidone, haloperidol, olanzapine, quetiapine, aripiprazole, paliperidone, levomepromazine, perphenazine | Juntendo University | Schizophrenia Relapse | 01/17 | 01/17 | | |
ChiCTR-POC-15006642: Follow-up study of the risk of relapse and the function after reducing high doses risperidone maintenance treatment in patient with schizophrenia |
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| Not yet recruiting | N/A | 100 | | risperidone dose reduced by 50% and then maintained ;risperidone dose kept constant | Guangzhou Brain Hospital (Guangzhou Huiai Hospital, The Affiliated Brain Hospital of Guangzhou Medical University); Guangzhou Brain Hospital (Guangzhou Huiai Hospital, The Affiliated Brain Hospital of Guangzhou Medical University), Guangzhou Municipal Health Bureau | schizophrenia | | | | |
NCT02906501: Effect of Risperidone on Cognitive Functions in Adolescents With ADHD and Behavioral Disturbances |
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| Unknown status | N/A | 45 | RoW | The Penn Web-Based Computerized Neurocognitive Battery, The Iowa Gambling Test (IGT) | Shalvata Mental Health Center | ADHD | 09/17 | 03/18 | | |
NCT01498770: An Observational Drug Utilization Study of Asenapine in the United Kingdom (P08308) |
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| Completed | N/A | 42 | NA | Asenapine, Sycrest, SCH 900274, Aripiprazole, Abilfy, Quetiapine, Seroquel, Risperidone, Risperdal, Olanzapine, Zyprexa, Ziprasidone, Iloperidone, Paliperidone, Lurasidone, Clozapine, Amisulpride, Sertindole, Zotepine | Organon and Co | Bipolar Disorder | 12/17 | 12/17 | | |
ChiCTR1800014844: The effect of antipsychotic on first-onset drug-naive schizophrenia: brain image, DNA methylation and gene expression study |
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| Completed | N/A | 80 | | Risperidone ;No | The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, National Natural Science Foundation of China | Schizophrenia | | | | |
| Completed | N/A | 296 | US | Caregiver psycho-education and skills training, Caregiver support available at the study site, Paliperidone palmitate, Chlorpromazine, Droperidol, Fluphenazine, Haloperidol, Loxapine, Perphenazine, Pimozide, Prochlorperazine, Thiothixene, Thioridazine, Trifluoperazine, Aripiprazole, Asenapine, Clozapine, Iloperidone, Olanzapine, Paliperidone, Quetiapine, Risperidone, Ziprasidone | Janssen Scientific Affairs, LLC | Schizophrenia | 07/18 | 07/18 | | |
NCT01878513: Prospective Cytochrome P450 Genotyping and Clinical Outcomes in Patients With Psychosis |
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| Completed | N/A | 88 | US | risperidone, Risperdal | Northwell Health | Schizophrenia, Schizoaffective Disorder, Psychotic Disorder Not Otherwise Specified, Severe Bipolar Disorder With Psychotic Features | 07/18 | 07/18 | | |
NCT03390712: Mirror-image Study of Paliperidone Palmitate and Risperidone Long-acting Injection |
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| Unknown status | N/A | 328 | Canada | Paliperidone Palmitate, Invega Sustenna, Risperidal Consta, Risperidone long-acting injection, Antipsychotic, Oral antipsychotics | Réseau de Santé Vitalité Health Network, Janssen Inc. | Schizophrenia Spectrum and Other Psychotic Disorders | 09/18 | 12/18 | | |
ChiCTR-ONN-17012021: The effect and mechanism of Ditan Huayu therapy in treating paranoid schizophrenia based on histogenous hypoxia |
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| Not yet recruiting | N/A | 120 | | oral risperidone ;risperidone combined Ditan Huayu Therapy ;none | The Affiliated Brain Hospital of Guangzhou Medical University(Guangzhou Huiai Hospital); The Affiliated Brain Hospital of Guangzhou Medical University(Guangzhou Huiai Hospital), Guangdong Province Administration of Traditional Chinese Medicine (program number: 20171209) and Guangzhou Huiai Hospital | paranoid schizophrenia | | | | |
NCT02034253: Glutamate, Brain Connectivity and Duration of Untreated Psychosis |
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| Completed | N/A | 134 | US | Risperidone, Risperdal | University of Alabama at Birmingham | Schizophrenia, Psychosis, Schizoaffective Disorder | 11/18 | 11/18 | | |
NCT04076371: The Treatment Efficacy of Combination Atypical Antipsychotics With Sertraline in Patients With Schizophrenia |
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| Completed | N/A | 1640 | NA | olanzapine-sertraline combination, olanzapine-sertraline, only olanzapine, risperidone-sertraline combination, risperidone-sertraline, only risperidone, paliperidone-sertraline combination, paliperidone-sertraline, only paliperidone, ziprasidone-sertraline combination, ziprasidone-sertraline, only ziprasidone | Beijing HuiLongGuan Hospital | Schizophrenia | 12/18 | 12/18 | | |
PAFIP_TLR, NCT02897167: Study of the Activation of Proinflammatory Pathways of Toll-like Receptors in Schizophrenia Patients |
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| Completed | N/A | 150 | Europe | Retrospective study of frozen samples, Prospective study of fresh samples | Fundación Marques de Valdecilla, Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Investigación Marqués de Valdecilla | Schizophrenia, Mental Disorders, Psychotic Disorders | 12/18 | 03/19 | | |
ChiCTR-IOR-16009579: The multi-dimensional evaluation of the individualized treatment of atypical antipsychotics |
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| Not yet recruiting | N/A | 800 | | Olanzapine ;Risperidone ;Aripiprazole ;Amisulpride | Shanghai Mental Health Center; Shanghai Mental Health Center, The project to promote the municipal hospital clinical skills and innovation action for three year | schizophrenia | | | | |
| Unknown status | N/A | 20 | Canada | Intervention, Antipsychotic Atypical, Risperidone, Quetiapine, Olanzapine | McMaster University, College of Family Physicians of Canada, MediSystem Pharmacy | Dementia, Behavior | 01/19 | 08/19 | | |
NCT02893371: Longitudinal Comparative Effectiveness of Bipolar Disorder Therapies |
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| Terminated | N/A | 1037352 | US | Lithium Carbonate, Lithobid, Lamotrigine, Lamictal, Valproic Acid, Depakote, Valproate, Oxcarbazepine, Trileptal, Carbamazepine, Equetro, Ziprasidone, Geodon, Risperidone, Risperdal, Quetiapine, Seroquel, Olanzapine, Zyprexa, Aripiprazole, Abilify, Fluoxetine / Olanzapine, Symbyax, Haloperidol, Haldol Decanoate, Perphenazine, Trilafon, Clozapine, Clozaril, Asenapine, Saphris, Lurasidone, Latuda, Paliperidone, Invega, Mirtazapine, Remeron, Remeronsoltab, Bupropion, Zyban, Aplenzin, Wellbutrin, Desvenlafaxine, Pristiq, Desfax, Duloxetine, Cymbalta, Irenka, Venlafaxine, Effexor XR, Citalopram, Celexa, Escitalopram, Lexapro, Fluoxetine, Prozac, Sarafem, Fluvoxamine, Faverin, Fevarin, Floxyfral, Dumyrox, Luvox, Paroxetine, Paxil, Seroxat, Sertraline, Zoloft, Vilazodone, Viibryd, Doxepin, Sinequan, Silenor | University of New Mexico, Patient-Centered Outcomes Research Institute, Montana State University, National Alliance on Mental Illness Montana, CGStat LLC, Risk Benefit Statistics LLC, National Alliance on Mental Illness New Mexico, National Alliance on Mental Illness Westside Los Angeles | Bipolar Disorder | 06/19 | 06/19 | | |
NCT02926976: The Optimal Treatment for Treatment-resistant Schizophrenia |
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| Unknown status | N/A | 150 | RoW | Risperidone with Clozapine, Risperidone Tablet, Aripiprazole with Clozapine, Aripiprazole Tablets, sodium valproate with Clozapine, Valproate, modified electroconvulsive therapy(MECT) with Clozapine, Magnetic seizure therapy(MST) with Clozapine, clozapine | Shanghai Mental Health Center | Schizophrenia | 09/19 | 09/19 | | |
ChiCTR1900023058: The effects of celecoxib plus risperidone on psychopathology, cognition and cytokine levels in chronic schizophrenia: a prospective, randomized, controlled clinical trial. |
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| Recruiting | N/A | 90 | | Risperidone4~6mg/d ;Risperidone 4~6mg/d, Celecoxib 200mg/d ;Risperidone 4~6mg/d, Celecoxib 400mg/d | Jingzhou Mental Hospital; Jingzhou Mental Hospital, Hospital Research Fund | schizophrenia | | | | |
NCT03007303: The Relevance Between the microRNA-30e in Plasma and the Prognosis of Schizophrenia Patients |
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| Unknown status | N/A | 30 | RoW | Atypical Antipsychotic, olanzapine, quetiapine , ziprasidone and risperidone, atypical antipsychotic combined with MECT, MECT means modified electric convulsive therapy | Dalian Seventh People's Hospital, TAKARA BIOTECHNOLOGY(DALIAN)CO.,LTD. | Schizophrenia, Micrognathia | 03/20 | 07/20 | | |
NCT03302364: A Research in Pharmacogenomics and Accurate Medication of Risperidone |
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| Unknown status | N/A | 800 | RoW | Risperidone, Risperidal | Cui Yimin | Schizophrenia, Mental Illness | 06/20 | 06/20 | | |
NCT00825045: Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia |
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| Unknown status | N/A | 14 | Canada | risperidone | Centre for Addiction and Mental Health | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder | 12/20 | 12/20 | | |
ChiCTR1900027767: Efficacy and safety of adjunctive low-concentration sevoflurane for the treatment of hospitalized acute schizophrenia: a multicenter, randomized, active-controlled clinical trial. |
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| Recruiting | N/A | 50 | | antipsychotics (Risperidone/Paliperidone/Olanzapine) and Sevoflurane ;antipsychotics (Risperidone/Paliperidone/Olanzapine) | Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, National Natural Science Foundation of China (81671116 and 81870823) | schizophrenia | | | | |
NCT06200584: Synergistic Effect of Vitamin E & D in Reducing Risk of Effects Associated With Atypical Anti-psychotics |
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| Completed | N/A | 140 | RoW | Risperidone, neuroleptics, Olanzapine, Quetiapine, Risperidone and Vitamin D and Vitamin E, vitamin, Olanzapine and Vitamin D and Vitamin E, Quetiapine and Vitamin D and Vitamin E | Dr Rabia Arshad | Antipsychotics and Neuroleptics Toxicity | 06/21 | 06/21 | | |
SWITCH, NCT04312503: Observational Study on the Effect of Switch to Lurasidone in Subjects With Schizophrenia" |
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| Completed | N/A | 95 | Europe | Lurasidone, Latuda, aripiprazole, olanzapine, quetiapine or risperidone | Aziende Chimiche Riunite Angelini Francesco S.p.A | Schizophrenia | 10/22 | 10/22 | | |
NCT02822092: Striatal Connectivity and Clinical Outcome in Psychosis |
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| Completed | N/A | 196 | US | Risperidone or Aripiprazole (patients only), Risperidal, Aripiprazole | Northwell Health, National Institutes of Health (NIH) | Psychotic Disorders | 12/23 | 12/23 | | |
NCT06128408: The Characteristics of Treatment Resistant Schizophrenia From the Illness Onset |
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| Not yet recruiting | N/A | 300 | NA | risperidone, olanzapine, aripiprazole | Peking University | Treatment-resistant Schizophrenia | 10/24 | 10/24 | | |
ChiCTR2200059183: Mechanism and application of intestinal flora regulating TLR4 / NF KB pathway on the anti schizophrenic effect of risperidone |
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| Not yet recruiting | N/A | 100 | | None | Wuxi Mental Health Center; Wuxi Mental Health Center, Wuxi Health Commission | Major depression disorder | | | | |
| Completed | N/A | 509 | US | Risperidone, Risperdal, Aripiprazole, Abilify | Duke University, The Emmes Company, LLC | Weight, Body | 11/23 | 11/23 | | |
POPS or POP02, NCT04278404: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) |
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| Recruiting | N/A | 5000 | Canada, US | The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care:, Aminocaproic acid, Amiodarone, Bosentan, Budesonide, Cefdinir, Cefepime, Ceftazidime, Clindamycin, Clobazam, Dexamethasone, Dexmedetomidine, Dextroamphetamine/Amphetamine, Fosfomycin, Furosemide, Gabapentin, Guanfacine, Hydrocortisone, Labetalol, Meropenem, Metformin, Milrinone, Nalbuphine, Nicardipine, Nifedipine, Oseltamivir, Oxycodone, Risperidone, Sertraline, Sevelamer Carbonate / Sevelamer Hydrochloride, Spironolactone, Terbutaline, Tranexamic acid, Voriconazole, Zolpidem, Azithromycin, Lopinavir/Ritonavir, Ribavirin, Tocilizumab, Anakinra, Aspirin, Canakinumab, Colchicine, Interferon, Remdesivir, Ruxolitinib, Sarilumab, Abatacept, Infliximab | Duke University, The Emmes Company, LLC, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome | 05/24 | 07/24 | | |
ChiCTR2100048395: Effect of ruprasidone on the clinical efficacy and serum BDNF level of early risperidone in the treatment of unresponsive first-episode schizophrenia |
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| Not yet recruiting | N/A | 200 | | Risperidone ;Early dressing change ;Cozapine | Huzhou Third People's Hospital; Huzhou Third People's Hospital, Huzhou Third People's Hospital | Schizophrenia | | | | |
NCT05473741: Risk of Breakthrough Symptoms With Long-Acting Injectable Medications |
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| Recruiting | N/A | 180 | Canada | Second Generation Long-Acting Injectable Antipsychotic Medications, paliperidone palmitate, risperidone, aripiprazole | Centre for Addiction and Mental Health, Janssen Inc. | Schizophrenia, Schizophrenia Relapse | 12/25 | 12/25 | | |
| Recruiting | N/A | 600 | | Risperidone ;None | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, The National Natural Science Foundation of China | schizophrenia (SCZ) | | | | |
