| risperidone / Generic mfg. |
| Completed | 4 | 501 | US | iloperidone, Fanapt™ | Novartis | Schizophrenia | 01/12 | 01/12 | | |
NCT00539071: High Dose Risperidone Consta for Patients With Schizophrenia With Poor Response to Risperidone |
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| Completed | 4 | 160 | US | long-acting injectable risperidone, long acting injectable risperidone, Risperidone Consta | Northwestern University, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia, Schizoaffective Disorder | 05/12 | 05/12 | | |
NCT02075528: Early Prediction of Clinical Response in Patients With Schizophrenia Treated by Paliperidone ER |
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| Completed | 4 | 41 | RoW | Paliperidone ER, 9-hydroxyrisperidone | Taipei City Hospital, Johnson & Johnson Taiwan Ltd, Taipei Institute of Pathology | Schizophrenia, Schizoaffective Disorder | 05/12 | 07/12 | | |
NCT01193166: Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital |
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| Withdrawn | 4 | 0 | US | paliperidone palmitate, risperidone, olanzapine, aripiprazole, haloperidole, quetiapine, perphenazine, paliperidone | Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 09/12 | 09/12 | | |
| Completed | 4 | 168 | US | Methylphenidate HCl, Concerta, Risperidone, Risperdal, Parent Management Training (PMT), Community Parent Education Program, Placebo | Michael Aman, National Institute of Mental Health (NIMH) | Attention Deficit Disorder With Hyperactivity | 11/12 | 11/12 | | |
SPICY, NCT00794625: Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The Study) |
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| Unknown status | 4 | 270 | US | Valproate, Depakote, Valproic acid, Risperidone, Risperdal, Placebo, Inactive substance, "Sugar pill", Stimulant medication, Ritalin, Dexedrine, Behavioral family counseling | Joseph Blader, University of Texas, Northwell Health | Attention Deficit Disorder With Hyperactivity | 11/12 | 04/13 | | |
NCT01109147 / 2009-017673-38: Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients |
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| Completed | 4 | 67 | Europe | Imagery, pharmacogenetic sampling | Qualissima | Schizophrenia, Undifferentiated Type | 01/13 | 05/13 | | |
NCT01592201: A Comparative Study of Patient Satisfaction Between Continued Administration of Previous Antipsychotics Versus Switched Administration to Paliperidone ER in Non-satisfied Patients With Previous Antipsychotic Drug |
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| Terminated | 4 | 13 | RoW | Paliperdidone ER, Aripiprazole, olanzapine and risperidone (Antipsychotics) | Janssen Korea, Ltd., Korea | Schizophrenia | 06/13 | 06/13 | | |
NCT02021201: The Effect of Sertindole and Risperidone on Endophenotypic Markers of Schizophrenia |
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| Terminated | 4 | 1 | Europe | risperidone, Risperdal, Sertindole, Serdolect | Birte Glenthoj, Icahn School of Medicine at Mount Sinai | Schizophrenia | 07/13 | 07/13 | | |
2013-001315-71: Dopaminergic genotype of schizophrenic patients and the benefit of adjunctive aripiprazole to risperidone treatment. The effect on hormonal and metabolic measures Perfil dopaminérgico de los pacientes esquizofrénicos que se beneficiarán de la adición de aripiprazol al tratamiento con risperidona/paliperidona. Efecto sobre parámetros hormonales y metabólicos |
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| Ongoing | 4 | 110 | Europe | Tablet, ABILIFY | Mercedes Zumarraga Ortiz, Fundación Vasca de Investigación Sanitaria (Bioef) | schizophrenia Esquizofrenia, schizophrenia Esquizofrenia, Psychiatry and Psychology [F] - Psychological processes [F02] | | | | |
NCT01157351: 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated |
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| Completed | 4 | 450 | US | paliperidone, risperidone, haloperidole, perphenazine, aripiprazole, quetiapine, paliperidone palmitate, olanzapine | Janssen Scientific Affairs, LLC | Schizophrenia | 12/13 | 12/13 | | |
NCT01813643: A Comparison of Risperidone and Aripiprazole for Treatment of Patirnts With Methamphetamine-Associated Psychosis |
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| Terminated | 4 | 50 | RoW | Risperidone, Risperdal H20070057, Aripiprazole, Aopai H20041507 | Wei Hao | Methamphetamine Dependence | 12/13 | 08/14 | | |
NCT01742390: A Multicenter Study to Evaluate the Effects of Switching to Aripiprazole 12 Weeks on the Sexual Dysfunction From Risperidone or Paliperidone in Patients With Schizophrenia Spectrum Disorders or Bipolar Spectrum Disorders |
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| Unknown status | 4 | 120 | RoW | Aripiprazole, risperidone or paliperidone | Si Tianmei | Sexual Dysfunction, Hyperprolactinemia | 12/13 | 06/14 | | |
ChiCTR-RNC-09000521: The genetic association study on individual difference of therapeutic effects of antipsychotic medication |
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| Completed | 4 | 2100 | | Risperidone 2-6mg/d; Olanzapine 5-20mg/d; Qutiapine 400-750mg/d; Ziprasidone 80-160 mg/d; Aripiprazole 10-30mg/d; Clozapine 200-600 mg/d; Perphenazine 20-60 mg/d | Sixth Hospital, Peking University; Ministry of Health, China, Ministry of Health, China. | schizophrenia | | | | |
NCT01822730: A Comparison of Paliperidone and Risperidone for Treatment of Patirnts With Methamphetamine-Associated Psychosis |
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| Completed | 4 | 120 | RoW | paliperidone, Paliperidone Extended-Release Tablets, Invega, Risperidone, Risperdal H20070057 | Wei Hao | Methamphetamine Dependence | 01/14 | 05/14 | | |
IMPACT, NCT00806234: Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics |
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| Completed | 4 | 127 | US | Aripiprazole or Perphenazine, Abilify, Trilafon, Metformin, Glucophage, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine, Zyprexa, Seroquel, Risperdal, Geodon, Abilify, Saphris, Sycrest, Fanapt, Fanapta, Zomaril, Latuda, Invega, Symbyax | Johns Hopkins University, National Institute of Mental Health (NIMH), University of Maryland, University of North Carolina, Chapel Hill, The Zucker Hillside Hospital | Psychotic Disorders | 03/14 | 03/14 | | |
NCT01844700: 1/2-MC4R Genotype and Pediatric Antipsychotic Drug- Induced Weight Gain |
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| Terminated | 4 | 14 | US | Ziprasidone, Geodon, aripiprazole, quetiapine, or risperidone, Abilify, Seroquel, Risperdal | Northwell Health | High Risk MC4R Genotype, Low Risk MC4R Genotype, One Week or Less Antipsychotic Lifetime Exposure | 04/14 | 04/14 | | |
| Terminated | 4 | 104 | Europe | C-ECT, Thrymatron System IV device (Somatics, LLC, ISO 13485:2003)., Pharmacotherapy:, Antidepressants:, - Venlafaxine 75-225 mg/d. N06AX16, - Duloxetine 60-120 mg/d. N06AX21, - Imipramine 100-300 mg/d. N06AA02, - Clomipramine 75-225 mg/d. N06AA04, - Nortriptyline 75-200 mg/d. 906AA10, - Sertraline 50-200 mg/d. N06AB06, -Fluoxetine 20-40 mg/d. N06AB03, - Citalopram 20-60 mg/d. N06AB04, - Paroxetine 20-40 mg/d. N06AB05, - Escitalopram 10-20 mg/d. N06AB10, - Mirtazapine 15-45 mg/d. N06AX11, - Mianserin 10-60 mg/d. 906AX03, - Trazadone 50-200 mg/d. 906AX05, - Reboxetin 2-12 mg/d. N06AX18, Antipsychotic drugs, - Olanzapine 2'5-20 mg/d. N05AH03, - Risperidone 0'5-9 mg/d. N05AX08, - Quetiapine 50-600 mg/d. N05AH04, - Aripiprazole 5-30 mg/d. N05AX12, Lithium: 200-1200 mg/d. 905AN01, Anxyiolitics:, - Diazepam 2'5-50 mg/d. N05BA01, - Clorazepate 5-50 mg/d. N05BA05, - Lorazepam 1-10 mg/d. N05BA06, PHARMACOTHERAPY | Hospital Universitari de Bellvitge | Depression | 07/14 | 07/14 | | |
NCT01458379: Brain Myelination Effects of Paliperidone Palmitate Versus Oral Risperidone in First Episode Schizophrenia |
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| Not yet recruiting | 4 | 50 | US | Paliperidone Palmitate, Risperidone | University of California, Los Angeles, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 10/14 | 12/15 | | |
NCT02918097: Cost- Effectiveness and Quality of Life Assessment in Bipolar Disorder Depressive Episode |
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| Completed | 4 | 78 | NA | Lithium Carbonate, Carbolitium, Sertraline, Zoloft, Nortriptyline, Pamelor, Risperidone, Risperdal | Federal University of Rio Grande do Sul | Bipolar Disorder | 11/14 | 09/15 | | |
NCT00320671: Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis |
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| Completed | 4 | 198 | US | Aripiprazole, Abilify, Risperidone, Risperdal | Northwell Health, National Institute of Mental Health (NIMH) | Schizophrenia | 12/14 | 12/15 | | |
TAAS, NCT02040883: Tandospirone Combined With Atypical Antipsychotic Drugs in Schizophrenia |
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| Unknown status | 4 | 100 | RoW | Risperidone/Olanzapine/Quetiapine/Ziprasidone/Aripiprazole, AAPD, Tandospirone, Sediel | Qingyun Yin | Schizophrenia | 12/14 | 12/14 | | |
NCT01670071: A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia |
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| Terminated | 4 | 17 | RoW | Paliperidone extended-release, Paliperidone, Risperidone immediate-release, Risperidone IR | Johnson & Johnson Taiwan Ltd | Schizophrenia | 06/15 | 06/15 | | |
JFR, NCT02593734: Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana |
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| Completed | 4 | 139 | RoW | olanzapine, Zyprexa, risperidone, Risperdal, amitryptaline, Elavil, fluoxetine, Prozac | University of Ghana Medical School | Schizophrenia, Mood Disorders,, Anxiety Disorder | 07/15 | 07/15 | | |
2004-004482-15: Hirnaktivierung während Gedächtnisaufgaben bei Patienten mit Schizophrenie unter Behandlung von Ziprasidon oder Risperidon. Eine FMRT-Untersuchung. |
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| Ongoing | 4 | 28 | Europe | Ziprasidon (Zeldox), Risperidon (Risperdal) Tablette, Risperidon (Risperdal) Lösung, Risperidon (Risperdal) Quicklet, Risperidon (Risperdal) Consta, Zeldox, Risperidon (Risperdal), Zeldox, Risperidon (Risperdal) | Universitätsklinikum Aachen, Klinik f. Psychiatrie und Psychotherapie | Patienten mit DSM-IVTR diagnostizierter Schizophrenie | | | | |
2005-000472-40: A Comparative, Randomized, Open -Label, Multicenter Study on the Efficacy and Safety of Switch Treatment with Aripiprazole in Schizophrenic Out-patients who areExperiencing Insufficient Efficacy with Risperidone and/or Safety and Tolerability Issues,While on Risperidone. Protocol version 1.0 , dated 31-Mar-05; and Pharmacogenetics Amendment 1, version 1.0 dated 13-Jul-05. |
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| | 4 | 42 | Europe | Abilify, Abilify, Abilify | Bristol-Myers Squibb International Corporation, BRISTOL-M.SQUIBB | Schizophrenia | | 04/07 | | |
2006-005394-22: ESCITALOPRAM MONOTHERAPY COMPARED TO COMBINATION OF ESCITALOPRAM AND RISPERIDONE IN THE TREATMENT OF ACUTE PSYCHOTIC DEPRESSION |
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| Ongoing | 4 | 50 | Europe | Cipralex, Risperdal, Cipralex, Risperdal, Cipralex, Risperdal | Turku university hospital | ICD-10 diagnosis F32.3; psykoottinen masennus, F 33.3; toistuva psykoottinen masennus. | | | | |
2007-004482-18: A blinded-initiation study of medication satisfaction in subjects with schizophrenia treated with paliperidone ER after suboptimal response to oral risperidone. |
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| Completed | 4 | 9 | Europe | INVEGA, Risperdal, INVEGA, Risperdal | Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | | 06/08 | | |
2008-001128-30: EFFICACY OF SERTINDOLE AS COMPARED TO OLANZAPINE OR RISPERIDONE ON PREATTENTIONAL AND ATTENTION-DEPENDENT FUNCTIONS IN PATIENTS WITH CHRONIC SCHIZOPHRENIA. A COGNITIVE AND FMRI STUDY. |
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| Completed | 4 | 48 | Europe | Serdolect, Zyprexa, Hunperdal, Serdolect, Zyprexa, Hunperdal | SE Dept. of Psychiatry and Psychotherapy | schizophrenia | | 10/11 | | |
2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD |
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| Ongoing | 4 | 300 | Europe | Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary) | King\'s College London, North Essex Partnership NHS Foundation Trust | Alzheimer\'s disease | | | | |
2009-012003-26: Evaluation of Growth, Sexual Maturation, and Prolactin-Related Adverse Events in the Pediatric Population Exposed to Atypical Antipsychotic Drugs |
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| | 4 | 40 | Europe | RISPERDAL, RISPERDAL | Janssen-Cilag International, NV | Long-term safety data in children and adolescents will be collected from a population of patients with a diagnosis of schizophrenia, bipolar mania, autistic disorder or conduct and other disruptive disorders undergoing routine standard of care treatment. | | 07/11 | | |
NCT02118688: Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium |
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| Withdrawn | 4 | 0 | US | Risperidone, Trazodone, Placebo | Rochester General Hospital | Delirium, Agitation | 03/16 | 03/16 | | |
NCT02307396: Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients |
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| Completed | 4 | 21 | Europe | Olanzapine, Amisulpride, Risperidone, Haloperidol, Quetiapine, Perphenazine, Sulpiride, bromperidol, Zuclopenthixol, Thioridazine, Paliperidone, Ziprasidone, Benperidol, Fluspirilene, Pimozide, Perazine, Fluphenazine, Flupentixole, Sertindole | Technische Universität München | Schizophrenia, Schizophrenia and Disorders With Psychotic Features, Schizoaffective Disorders | 06/16 | 06/16 | | |
NCT01913327: Antipsychotic Effects on Brain Function in Schizophrenia |
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| Terminated | 4 | 4 | US | Aripiprazole, Abilify, Risperidone, Risperdal, Modafinil, Provigil | University of California, San Francisco, The Dana Foundation | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder | 01/17 | 01/17 | | |
| Completed | 4 | 49 | US | Clozapine, Clozaril, Risperidone, Risperdal | Dartmouth-Hitchcock Medical Center, University of South Carolina, Michigan State University, University of Miami, University of Massachusetts, Worcester | Schizophrenia, Cannabis Abuse, Cannabis Dependence, Dual Diagnosis | 03/17 | 03/17 | | |
NCT02634320: A Study of Aripiprazole Lauroxil (Also Known as ARISTADA TM) in Subjects With Schizophrenia |
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| Completed | 4 | 51 | US | Aripiprazole Lauroxil, ARISTADA | Alkermes, Inc. | Schizophrenia | 07/17 | 07/17 | | |
NCT02282085: Treatment Study Comparing Aripiprazole Once Monthly With Standard of Care Medication in Outpatients With Schizophrenia |
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| Unknown status | 4 | 200 | US | Aripiprazole Once-Monthly, Oral Antipsychotic (i.e. aripiprazole, risperidone, lurasidone, quetiapine, olanzapine, ziprasidone, etc) | Matt Byerly, Otsuka America Pharmaceutical | Schizophrenia | 12/17 | | | |
NCT02063945: Methylphenidate vs. Risperidone for the Treatment of Children and Adolescents With ADHD and Disruptive Disorders |
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| Terminated | 4 | 5 | RoW | Methylphenidate, Ritalin, Ritalin SR, Ritalin LA, Concerta, Risperidone, Risperdal | Sheba Medical Center | Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder | 02/18 | 02/18 | | |
PAFIP3_1Y, NCT02532491: Effectiveness of Second Generation Antipsychotics in First Episode Psychosis Patients: 1-year Follow-up |
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| Unknown status | 4 | 200 | Europe | Aripiprazole, Abilify, Risperidone, Risperdal | Fundación Marques de Valdecilla, Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Investigación Marqués de Valdecilla | Schizophrenia, Psychotic Disorders | 05/18 | 12/20 | | |
2015-000641-23: Clinical Trial of Risperidone for Irritability and Aggression after a Head Injury |
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| Completed | 4 | 50 | Europe | generic risperidone, Capsule, risperidone- generic product | Central and North West London NHS Foundation Trust | aggression and agitation following on from a traumatic brain injury, aggression and agitation following on from a traumatic brain injury, Psychiatry and Psychology [F] - Behaviours [F01] | | | | |
NCT03075657: Study of add-on Ramelteon Therapy on Sleep and Circadian Rhythm Disruption in Patients With Schizophrenia |
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| Completed | 4 | 120 | RoW | Risperidone, Risperidone and Ramelteon, Haloperidol, Haloperidol and Ramelteon | All India Institute of Medical Sciences, Bhubaneswar | Schizophrenia | 06/18 | 08/18 | | |
ChiCTR1900027504: Effect of different dosage of aripiprazole on preventing risperidone-induced hyperprolactinemia: a 8-week, multicenter, randomized, open-label, controlled trial |
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| Completed | 4 | 105 | | Patients treated with risperidone alone for 8 weeks ;Patients treated with risperidone and 5 mg/day aripiprazole for 8 weeks ;Patients treated with risperidone and 10 mg/day aripiprazole for 8 weeks | Shandong Mental Health Center; ShanDong Mental Health Center, Self financing | Schizophrenia | | | | |
NCT02237417: Study of the Impact of Aripiprazole (Abilify®) Once Monthly Versus Standard of Care Oral Antipsychotic Medications on Changes in Brain Structure and Metabolism |
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| Completed | 4 | 47 | US | Standard of Care Oral antipsychotics, IM aripiprazole once monthly, No Treatment | Deborah Yurgelun-Todd, Otsuka America Pharmaceutical | Schizophrenia | 11/18 | 07/20 | | |
2017-002406-12: HAMLETT. Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment. A study comparing continuation versus discontinuation/dose reduction of antipsychotic medication in patients remitted after a first episode of psychosis HAMLETT. Handling Antipsychotic Medication: Lange termijn evaluatie van specifiek toegepaste medicatie. Vergelijking tussen het doorgaan met antipsychotische medicatie bij patiënten die hersteld zijn van eerste psychotische episode en vroegtijdig afbouwen/stoppen. |
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| Not yet recruiting | 4 | 512 | Europe | RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE, CID5073, CID135398745, CID5002, CID60795, CID3559, CID5355, CID115237, CID16362, CID213046, CID135398737, CID2159, CID5467, CID60149, CID667467, CIS5311507, Tablet, RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE | University Medical Center Groningen, ZonMw | HAMLETT compares regular treatment guidelines for patients in remission after a first episode of psychosis, namely continuation with antipsychotic medication for at least one year, with early dose reduction/discontinuation. HAMLETT vergelijkt de reguliere behandeling van patiënten in remissie na een eerste psychotische episode zoals beschreven in de richtlijnen, namelijk het continueren van antipsychotica voor minstens 1 jaar, met het vroegtijdig afbouwen/stoppen met medicatie., HAMLETT compares continuation versus early discontinuation of antipsychotic medication in patients who have recovered from their first episode of psychosis. HAMLETT vergelijkt de reguliere behandeling van patiënten die hersteld zijn van een eerste psychose, namelijk minimaal 1 jaar antipsychotica gebruiken, met vroegtijdig afbouwen/stoppn met medicatie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 60 | Europe | DM-Aripiprazole, DM-Olanzapine, DM- Quetiapine, DM-Risperidone, Tablet, Aripiprazole, Olanzapine, Quetiapine, Risperidone | Otsuka Pharmaceutical, Otsuka Pharmaceutical | Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT03568500: A Trial to Explore Acceptance and Performance of Using a Digital Medicine System With Healthcare Professionals and Adults With Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis on an Oral Atypical Antipsychotic |
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| Completed | 4 | 44 | Europe | Digital Medicine System, Aripiprazole, Olanzapine, Quetiapine, Risperidone | Otsuka Pharmaceutical Development & Commercialization, Inc. | Schizophrenia, Schizoaffective Disorder, First Episode Psychosis | 05/19 | 09/19 | | |
| Unknown status | 4 | 200 | Europe | Aripiprazole, Abilify, Risperidone, Risperdal | Fundación Marques de Valdecilla, Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Investigación Marqués de Valdecilla | Schizophrenia, Psychotic Disorders, Psychosis | 06/19 | 06/21 | | |
NCT02562287: Clozapine Versus Other Atypical Antipsychotics for Bipolar Disorder |
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| Unknown status | 4 | 54 | RoW | Clozapine, Clozaril, Risperidone, Risperdal, Olanzapine, Zyprexa, Quetiapine, Seroquel | Hospital de Clinicas de Porto Alegre, Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior., Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico | Bipolar Disorder | 06/19 | 12/20 | | |
NCT03713658: A Study to Evaluate the Ability of Conducting a Study of Oral Risperidone Followed by Paliperidone Palmitate in Rwandan Healthcare Facilities |
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| Completed | 4 | 34 | RoW | Risperidone 3 mg, Paliperidone Palmitate 50 mg eq., R092670, Paliperidone Palmitate 75 mg eq., Paliperidone Palmitate 100 mg eq., Paliperidone Palmitate 150 mg eq., Paliperidone Palmitate 175 mg eq., Paliperidone Palmitate 263 mg eq., Paliperidone Palmitate 350 mg eq., Paliperidone Palmitate 525 mg eq. | Janssen Research & Development, LLC | Schizophrenia | 12/19 | 12/19 | | |
NCT03148509: A Study of Diagnosis and Treatment of Depression Based on Biological Evidence of Dopamine Reward Pathway |
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| Unknown status | 4 | 300 | NA | risperidone, aripiprazole, bupropion | Peking University | Diagnosis and Treatment of Depression | 12/19 | 12/19 | | |
ChiCTR1800016707: Effects of Four Antipsychotics on Social Cognitive Function and Metabolism in Patients with Stable Schizophrenia |
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| Recruiting | 4 | 275 | | clozapine ;chlorpromazine ;risperidone ;olanzapine ;no | Mental Health Center of Xuhui District Shanghai; Mental Health Center of Xuhui District Shanghai, Shanghai Municipal Commission of Health and Family Planning | schizophrenia | | | | |
ChiCTR1900022365: Tropisetron plus standard care versus placebo to improvement of cognitive impairment for people with schizophrenia: a randomized controlled trial |
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| Not yet recruiting | 4 | 40 | | Tropisetron combined with Risperidone ;Placebo combined with Risperidone | Beijing An'ding Hospital, Capital Medical University; Beijing An'ding Hospital, Capital Medical University, Beijing Municipal Administration of Hospitals'Youth Programme ' Talent cultivation in Beijing Anding Hospital (subject nova) | schizophrenia | | | | |
NCT03510325: Chinese First Episode Schizophrenia's Optimal Dynamic Antipsychotic Treatment Regime |
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| Unknown status | 4 | 1260 | RoW | Olanzapine, Risperidone, Aripiprazole, Amisulpride, Paliperidone long-acting injection | Shanghai Mental Health Center | Schizophrenia | 09/20 | 09/21 | | |
PAFIP3_nc3Y, NCT03883204: Neurocognitive Effectiveness in Treatment of First-episode Non-affective Psychosis: 3-years Follow-up |
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| Unknown status | 4 | 115 | Europe | Aripiprazole, Abilify, Risperidone, Risperdal | Fundación Marques de Valdecilla, Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Investigación Marqués de Valdecilla | Schizophrenia, Psychotic Disorders, Psychosis | 12/20 | 12/20 | | |
| Recruiting | 4 | 2000 | | Risperidone ;Olanzapine ;Aripiperazole ;Quetiapine | 国家科技部; Peking University Sixth Hospital, The Ministry of Science and Technology | Schizophrenia | | | | |
2020-005450-18: Can we improve antipsychotic medication safety by measuring medication blood concentration in children and adolescents. |
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| Ongoing | 4 | 140 | Europe | Tablet, Risperidone | Erasmus MC, Erasmus MC | irritability in autism spectrum disorder, Irritability and aggression in children with autism., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT01451736: Oral Risperidone Versus Injectable Paliperidone Palmitate for Treating First-Episode Schizophrenia |
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| Completed | 4 | 146 | US | paliperidone palmitate, Invega Sustenna, risperidone, Risperdal | University of California, Los Angeles, National Institute of Mental Health (NIMH), Janssen Scientific Affairs, LLC | Schizophrenia (Recent-onset) | 12/21 | 12/21 | | |
2021-003588-85: Individualized care with antipsychotics in patients suffering from schizophrenia spectrum disorders |
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| Not yet recruiting | 4 | 100 | Europe | Olanzapine, Risperidone, Tablet, , Aripiprazole, Olanzapine, Risperidone | UCLouvain, FNRS | Schizophrenia, schizoaffective disorders,psychosis not otherwise specified, and dellusional disorders, psychosis, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT04446234: Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building |
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| Not yet recruiting | 4 | 350 | RoW | Risperidone, Aripiprazole, Ziprasidone, Amisulpride, Quetiapine | Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine | Schizophrenia | 12/22 | 12/22 | | |
2022-001582-12: Open, multicenter, randomized clinical trial to evaluate the efficacy and safety of aripiprazole vs paliperidone / risperidone using multi-omics data in patients with a first psychotic episode. Ensayo clínico abierto, multicéntrico, aleatorizado para evaluar la eficacia y seguridad de aripiprazol vs paliperidona / risperidona mediante datos multi-ómicos en pacientes con un primer episodio psicótico. |
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| Ongoing | 4 | 244 | Europe | Injection, Abilify Maintena, Xeplion | Consorcio Centro de Investigacion Biomedica en Red (CIBER), Instituto de Salud Carlos III | First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT03323437: Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia |
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| Completed | 4 | 26 | US | Risperidone | Weill Medical College of Cornell University, New York State Psychiatric Institute, Columbia University, National Institute of Mental Health (NIMH) | Schizophrenia Spectrum and Other Psychotic Disorders | 05/23 | 05/23 | | |
ChiCTR2200066865: The strategy of use, efficacy and safety of Rykindo in the treatment of schizophrenia spectrum disorders：a prospective, single-arm, multicenter real-world study |
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| Recruiting | 4 | 300 | | Long-acting injectable risperidone | Beijing Huilongguan Hospital; Beijing Huilongguan Hospital, Corporate Grants | Schizophrenia spectrum disorders | | | | |
NCT06236451: Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia |
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| Recruiting | 4 | 60 | RoW | Aripiprazole, Risperidone | All India Institute of Medical Sciences, Bhubaneswar | Schizophrenia | 08/25 | 09/25 | | |
| Recruiting | 4 | 140 | Europe | Therapeutic Drug Monitoring, Risperidone plasma level | Erasmus Medical Center, Stichting de Merel, ZonMw: The Netherlands Organisation for Health Research and Development | Autism Spectrum Disorder | 05/24 | 05/24 | | |
CASPAR, NCT04940039: A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings |
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| Completed | 4 | 93 | RoW | Risperidone 3 mg, Paliperidone Palmitate 50 mg eq., R092670, Paliperidone Palmitate 75 mg eq., Paliperidone Palmitate 100 mg eq., Paliperidone Palmitate 150 mg eq., Paliperidone Palmitate 175 mg eq., Paliperidone Palmitate 263 mg eq., Paliperidone Palmitate 350 mg eq., Paliperidone Palmitate 525 mg eq. | Janssen-Cilag International NV | Schizophrenia | 04/24 | 04/24 | | |
| Terminated | 4 | 5 | US | Lumateperone, Caplyta, Risperidone, Risperdol | University of New Mexico | Psychosis | 02/24 | 02/24 | | |
SchizOMICS, NCT06060886: Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis |
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| Not yet recruiting | 4 | 244 | NA | Aripiprazole, Paliperidone | Consorcio Centro de Investigación Biomédica en Red (CIBER), Instituto de Salud Carlos III | Schizophrenia, Treatment-resistant Schizophrenia, Side Effect, Lipid Metabolism Disorders, Diabetes, NAFLD, Psychosis | 06/25 | 12/25 | | |
| Recruiting | 4 | 524 | US | clozapine, Clozaril, risperidone, Risperdal | University of Texas Southwestern Medical Center, National Institute of Mental Health (NIMH), Beth Israel Deaconess Medical Center, Hartford Hospital, University of Georgia, University of Chicago | Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder | 12/25 | 03/26 | | |
NCT05741502: An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine |
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| Recruiting | 4 | 60 | US | Clozapine, Antipsychotics,Other (non-Clozapine), Including Olanzapine, Risperidone, Paliperidone, Quetiapine, Aripiprazole, Ziprasidone, Lurasidone, Cariprazine, and all Typical antipsychotics | Ohio State University | Treatment-resistant Schizophrenia | 03/26 | 06/26 | | |
NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder |
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| Not yet recruiting | 4 | 80 | NA | Hydroxyzine, Atarax, Vistaril, Escitalopram Oxalate, citalopram, fluoxetine, fluvoxamine, paroxetine, paroxetine CR, sertraline, venlafaxine XR,, Alprazolam, clomipramine, clonazepam, diazepam, imipramine, lorazepam, mirtazapine, reboxetine, Bupropion SR, divalproex, duloxetine, gabapentin, levetiracetam, milnacipran, moclobemide, olanzapine, phenelzine, quetiapine, risperidone, tranylcypromine | Sultan Qaboos University | Panic Disorder | 12/26 | 12/26 | | |
NCT04478838: "Extended" (Alternate Day) Antipsychotic Dosing |
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| Recruiting | 4 | 120 | Canada | Risperidone, Risperdal, Olanzapine, Zyprexa, Apo-Olanzapine, Sandoz-Olanzapine | Centre for Addiction and Mental Health | Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents | 09/27 | 09/28 | | |
ACTRN12605000556640: Seroquel compared to Risperidone in the treatment of psychotic disorders adolescents. |
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| Completed | 3/4 | 60 | | | Dr Harith Swadi, AstraZeneca | Adolescent psychosis | | | | |
2007-004740-79: A One-Year Randomized, Prospective, Parallel, Open Comparison of Subjective Well-being in Schizophrenic Out-patients Treated with Quetiapine XR (SEROQUEL Prolong®) or Oral Risperidone at Flexible Dose in a Naturalistic Setting |
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| Completed | 3/4 | 916 | Europe | Seroquel XR, Prolonged-release tablet, Tablet, Risperdal 1 mg, Risperdal 2 mg, Risperdal 3 mg | AstraZeneca GmbH, ASTRAZENECA | Schizophrenia | | | | |
2010-021884-34: Relapse prevention in children and adolescents with aggressive anti-social behavior treated with risperidone: a randomized double blind, placebo-controlled, discontinuation study. |
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| Ongoing | 3/4 | 80 | Europe | Risperidone, 6000803, Risperidone, Risperidone | Radboud University Medical Centre Nijmegen, Radboud University, Radboud University Medical Centre Nijmegen, Comisión Europea | Conduct Disorder DSM-IV-TR; 312.8x, APA 2000 | | | | |
2011-000567-26: A randomized double-blind, placebo-controlled study of risperidone in the treatment of aggressive antisocial behavior in youth. |
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| Ongoing | 3/4 | 88 | Europe | Risperidone, 6000803, Risperidone, Risperidone | Radboud University Medical Centre Nijmegen, Radboud University Medical Centre Nijmegen, Comisión Europea | Conduct Disorder DSM-IV-TR; 312.8x¸ APA, 2000 | | | | |
