SUGARNSALT, NCT06217302: Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease |
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| Not yet recruiting | 3 | 150 | Canada, US | Sotagliflozin, INPEFA, Placebo | Alessandro Doria, Juvenile Diabetes Research Foundation, Canadian Institutes of Health Research (CIHR), The Kidney Foundation of Canada, The Cleveland Clinic, University of Washington, University of Michigan, University of Minnesota, University of Colorado, Denver, Northwestern University, Washington University School of Medicine, State University of New York - Upstate Medical University, Providence Medical Research Center, Stanford University, Montefiore Medical Center, University of Toronto, University Health Network, Toronto, University of Calgary, University of Alberta, University of British Columbia, Institut de Recherches Cliniques de Montreal, LMC Diabetes & Endocrinology Ltd., Joslin Diabetes Center, Lexicon Pharmaceuticals, DexCom, Inc. | Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure | 08/28 | 12/28 | | |
2017-002309-36: Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients with Mild to Moderate Hypertension |
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| Ongoing | 2 | 40 | Europe | Sotagliflozin, Jardiance, SAR439954, Film-coated tablet, Capsule, Jardiance | SANOFI-AVENTIS RECHERCHE ET DEVELOPPEMENT, SANOFI-AVENTIS RECHERCHE ET DEVELOPPEMENT | Diabetes mellitus, Diabetes mellitus, Diseases [C] - Nutritional and Metabolic Diseases [C18] | | | | |
| Not yet recruiting | 2 | 320 | NA | Sotagliflozin, Placebo | University of Dundee, Lexicon Pharmaceuticals, Juvenile Diabetes Research Foundation | Type 1 Diabetes, Heart Failure | 06/26 | 06/26 | | |
ASPIRE, NCT06072326: Ambrisentan Sotagliflozin and Prevention of Renal Injury; a Randomized Evaluation |
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| Not yet recruiting | 2 | 36 | Europe, Canada, US | Sotagliflozin, Ambrisentan, Ambrisentan and Sotagliflozin | University Medical Center Groningen, Juvenile Diabetes Research Foundation, Lexicon Pharmaceuticals | Type 1 Diabetes Mellitus With Diabetic Nephropathy | 03/25 | 03/25 | | |