leflunomide / Generic mfg.  >>  Phase 1
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10 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
leflunomide / Generic mfg.
ChiCTR-TRC-10001014: Randomized Controlled Study to Evaluate the Clinical Outcomes of Rheumatoid Arthritis Treated with Method of Activating Blood Circulation by Removing Blood Stasis

Completed
1
120
 
observation group: Leflunomide Tablets, from the first day to the third day, 50mg, qd, po, then 20mg, qd, po. Ligustrazine Powder-Needle, 0.12g, solubling in 5% GS/NS 100ml, qd, iv, in 30 to 60 minutes. ;control group: Leflunomide Tablets, from the first day to the third day, 50mg, qd, po, then 20mg, qd, po.
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences; Level of the institution：, Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences
Rheumatoid Arthritis
 
 
NCT04361214: Leflunomide in Mild COVID-19 Patients

Terminated
1
11
US
Leflunomide
University of Chicago
COVID-19
01/22
01/22
NCT05247203: Telitacicept Study in Chinese Subjects With Systemic Lupus Erythematosus

Completed
1
92
RoW
Telitacicept, RC18, standard therapy
RemeGen Co., Ltd.
Systemic Lupus Erythematosus
10/23
11/23
NCT04370483: Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma

Active, not recruiting
1
1
US
Leflunomide, Arava, SU101, Quality-of-Life Assessment, Quality of Life Assessment
City of Hope Medical Center, National Cancer Institute (NCI)
Smoldering Plasma Cell Myeloma
12/24
12/24
ChiCTR2300077294: Clinical efficacy evaluation of traditional Chinese medicine fumigation therapy in the treatment of rheumatoid arthritis with cold and dampness obstruction

Completed
1
60
 
Local fumigation with traditional Chinese medicine prescription; Methotrexate tablets combined with leflunomide tablets for oral treatment
Jiangxi Provincial People's Hospital; Jiangxi Provincial People's Hospital, Science and Technology Plan of Jiangxi Provincial Administration of Traditional Chinese Medicine
(rheumatoid arthritis)
 
 
NCT06228443: Bioequivalence Study of Generic Leflunomide 20 mg Film-coated Tablets and Reference Product Under Fasting Conditions

Not yet recruiting
1
48
NA
Leflunomide 20 mg Film-coated Tablet, ARAVA® 20 mg Film-coated Tablet
International Bio service
Healthy Volunteer
04/24
04/24
NCT06454383: Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

Recruiting
1
19
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Cholestyramine, Cholybar, Colestyramine, Duolite AP143 Resin, Questran, Questran Light, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Diagnostic Imaging, Medical Imaging, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Leflunomide, Arava, SU101, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI
City of Hope Medical Center, National Cancer Institute (NCI)
Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Pancreatic Ductal Adenocarcinoma
11/26
11/26
NCT04212416: Leflunomide in Treating Patients with Steroid Dependent Chronic Graft Versus Host Disease

Active, not recruiting
1
18
US
Leflunomide, Arava, SU101
City of Hope Medical Center, National Cancer Institute (NCI)
Chronic Graft Versus Host Disease, Steroid Refractory Graft Versus Host Disease
11/24
11/24
NCT05443425: Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

Recruiting
1
18
US
Cholestyramine, Cholybar, Colestyramine, Duolite AP143 Resin, Questran, Questran Light, Leflunomide, Arava, SU101, Steroid Therapy
City of Hope Medical Center, National Cancer Institute (NCI)
Acute Graft Versus Host Disease, Hematopoietic and Lymphoid System Neoplasm
07/25
07/25
NCT04997993: Leflunomide in Patients With PTEN-Altered Advanced Solid Malignancies

Recruiting
1
24
US
Leflunomide
Deborah Doroshow
PTEN-null Advanced Solid Tumors
09/26
09/26

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