| Monofer (iron isomaltoside 1000) / Pharmacosmos |
| Ongoing | 4 | 100 | Europe | COSMOFER, VENOFER, MONOFER, B03AB04, , Solution for infusion in administration system, COSMOFER, VENOFER, MOnofer | Hull and East Yorkshire Hospitals NHS Trust | patients with known chonic kidney disease with functional or absolute Iron deficiency Anaemia, and are greater than 18 years will be given repleacement iron therapy accoring to current local protocols and NICE guidelines | | | | |
2013-004979-13: A Placebo Study Comparing Intravenous Iron with Saline in Treatment of Low Blood Count before Surgery in Patients with Cancer of the Kidney, Bladder or Lower Abdominal Cavity Et placebokontrolleret lodtrækningsforsøg med intravenøst jern til behandling af lav blodprocent før operation hos patienter med kræft i nyre, blære eller bagerst i bugvæggen |
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| Ongoing | 4 | 84 | Europe | Monofer, Monofer, Monofer | Rigshospitalet, 2032, Pharmacosmos A/S | Iron deficiency anaemia and anaemia of chronic disease Jernmangelanæmi og anæmi ved kronisk sygdom | | | | |
2016-004439-19: Intravenous iron for treatment of anaemia before cardiac surgery |
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| Ongoing | 4 | 1000 | Europe | Iron(III) isomaltoside 1000 (Monofer), Solution for injection/infusion, Iron(III) isomaltoside 1000 (Monofer) | Alfred Health, National Health and Medical Research Council | Anaemia, Anaemia, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
2018-001669-17: ICaRAS - A Feasibility Study of Intravenous Iron Therapy for Anaemia in Palliative Cancer Care |
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| Ongoing | 4 | 40 | Europe | Iron Isomaltoside 100mg in 1ml solution for infusion, Solution for infusion, Iron Isomaltoside 100mg in 1ml solution for infusion | Nottingham University Hospitals NHS Trust, NIHR - Research for Patient Benefit | Iron deficiency anaemia secondary to cancer, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
2019-004370-26: Intravenous Iron Products and Phosphaturia in patients with Chronic Kidney Disease |
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| Not yet recruiting | 4 | 30 | Europe | Monofer, Ferinject, Solution for injection/infusion, Solution for injection, Monofer, Ferinject | Hull University Teaching Hospitals NHS Trust, Pharmacosmos A/S | Iron deficiency anaemia associated with Chronic Kidney Disease, Anaemia because of low iron associated with chronic kidney disease, Body processes [G] - Metabolic Phenomena [G03] | | | | |
2019-002661-35: FERRIC-CABG: Effect of Iron Isomaltoside in Patients Undergoing CoronaryArtery Bypass Grafting +/- Valve Surgery. |
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| Not yet recruiting | 4 | 240 | Europe | Solution for injection/infusion, MONOFER | King's College London, King's College Hospital NHS Foundation Trust, British Heart Foundation | Coronary or heart valve disease needing cardiac surgery, Coronary or heart valve disease needing cardiac surgery, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2021-005383-22: Cognitive Function, Depression, Anxiety, and Quality of Life in Chronic Heart Failure Patients with Iron Deficiency with and without Anaemia: Effects of Intravenous Iron (Ferric Derisomaltose) |
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| Not yet recruiting | 4 | 36 | Europe | MonoFer 100 mg/ml, Solution for infusion, MonoFer 100 mg/ml | Universitätsmedizin Göttingen, Pharmacosmos A/S | Iron deficiency in patients with chronic heart failure and mild cognitive impairment, Iron deficiency in patients with chronic heart failure and mild cognitive impairment, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
IVIronPPH, NCT04505514: Single Dose Intravenous Iron Isomaltoside in Combination With Oral Iron vs Oral Iron Monotherapy in Patients With Anemia After Postpartum Haemorrhage |
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| Recruiting | 4 | 60 | RoW | Iron Isomaltoside 1000, Placebo, Iberet-Folic-500 | University of Malaya | Post Partum Hemorrhage, Anemia | 10/22 | 12/22 | | |
NCT04346004: Effect of Preoperative Iron Isomaltoside 1000 Administration on Hemoglobin Concentration in Patients Undergoing Transcatheter Aortic Valve Implantation |
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| Recruiting | 4 | 214 | RoW | Normal saline, Iron isomaltoside | Yonsei University | Aortic Stenosis (Treated With TAVI) | 03/23 | 03/23 | | |
| Not yet recruiting | 4 | 32 | US | Monoferric | Brigham and Women's Hospital, Pharmacosmos A/S | Anemia, Surgery | 03/23 | 04/23 | | |
PICS, NCT04608539: A Clinical Trial Assessing the Efficacy of Intravenous Iron for the Treatment of Anemia Following Cardiac Surgery |
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| Completed | 4 | 110 | Europe | Ferric Derisomaltose, MonoFer, iron isomaltoside 1000, Ferrous sulfate, Ferro Duretter, normal saline, 0.9% natriumchloride | Michael Kremke, Aarhus University Hospital, University of Aarhus, Pharmacosmos A/S | Anemia Postoperative | 06/23 | 06/23 | | |
2020-001389-12: Intravenous iron for the treatment of anaemia following cardiac surgery |
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| Not yet recruiting | 4 | 110 | Europe | Solution for injection, Tablet, MonoFer, Ferro Duretter | Aarhus University Hospital, Aarhus University Hospital, Aarhus, Pharmacosmos A/S, Holbæk | Anaemia following cardiac surgery, Anaemia following cardiac surgery, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
| Completed | 4 | 1000 | RoW | Ferric carboxymaltose, ferinject, Iron isomaltoside, Placebo, No active drug | Bayside Health, National Health and Medical Research Council, Australia, Monash University | Anaemia | 04/24 | 09/24 | | |
NCT05804071: Analysis of the Effect of Iron Supplements on Iron Deficiency Anemia in Pregnancy |
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| Recruiting | 4 | 452 | RoW | Niferex, MonoFer | Qianfoshan Hospital | Iron Deficiency Anemia of Pregnancy, Iron Storage Disease | 01/24 | 01/25 | | |
| Completed | 4 | 4368 | RoW | Ferric carboxymaltose, Iron isomaltoside, Ferric derisomaltose, Ferric Sulfate, Ferric sulphate | Thomas Jefferson University, Children's Investment Fund Foundation, Jawaharlal Nehru Medical College, S. Nijalingappa Medical College, Raichur Institute of Medical Sciences, Sawai Mansingh Medical College | Iron Deficiency Anemia, Infant, Low Birth Weight, Anemia of Pregnancy | 12/23 | 01/24 | | |
| Recruiting | 4 | 94 | Europe | Iron isomaltoside, Iron Carboxymaltose | Lucie Favre | Hypophosphatemia, Roux-en-Y Gastric Bypass | 06/26 | 06/26 | | |
COREVIVE-HFrEF, NCT05971732: The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life |
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| Recruiting | 4 | 146 | RoW | Ferric derisomaltose, Monofer, Iron (III) isomaltoside 1000, Placebo, Normal saline | China-Japan Friendship Hospital | Heart Failure With Reduced Ejection Fraction, Iron Deficiency, Acute Heart Failure | 08/24 | 08/25 | | |
COREVIVE-HFpEF, NCT05991128: The Effects of Ferric Derisomaltose in Patients With Acute Heart Failure and Iron Deficiency on Exercise Capacity and Quality of Life |
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| Recruiting | 4 | 170 | RoW | Ferric derisomaltose, Monofer, Iron (III) isomaltoside 1000, Placebo, Normal saline | China-Japan Friendship Hospital | Heart Failure With Preserved Ejection Fraction, Iron Deficiencies, Acute Heart Failure | 08/24 | 08/25 | | |
ChiCTR2300074150: Efficacy and Safety of Monofer (Iron Isomaltate) in the Treatment of postoperative anemia in patients with Spinal Metastasis: a Randomized, controlled, open-label Clinical trial |
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| Not yet recruiting | 4 | 92 | | Iron isomaltoside on the third postoperative day (according to the recommendations of the drug manufacturer), and the maximum dose of iron isomaltoside was limited to 20mg/Kg.; Ferrous succinate tablets 200mg bid on the third day after operation, a total of 400mg per day, continuous oral administration for 28 days. | Shanghai Changzheng Hospital; Shanghai Changzheng Hospital, Cosmos Pharmaceutical Technology (Beijing) Co., Ltd. | spinal metastases patients with iron deficiency anemia after operation | | | | |
| Recruiting | 4 | 66 | US | Ferric Derisomaltose 1000 Mg in 100 mL INTRAVENOUS SOLUTION [Monoferric], Monoferric, Placebo, Normal Saline | Massachusetts General Hospital, National Heart, Lung, and Blood Institute (NHLBI), Pharmacosmos A/S, National Institutes of Health (NIH) | Iron-deficiency, Heart Failure With Preserved Ejection Fraction | 02/25 | 05/25 | | |
NCT05714007: The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery |
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| Recruiting | 4 | 120 | RoW | Ferric derisomaltose, MONOFER®, Ferrous succinate | Peking Union Medical College Hospital, Pharmacosmos A/S | Perioperative Anemia, Surgery, Spinal Deformity, Adult | 06/25 | 06/25 | | |
ChiCTR2300072661: Comparison of clinical outcome and pharmacoeconomics of high-dose intravenous iron(Iron Isomaltoside Injection) and oral iron in that treatment of iron deficiency anemia |
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| Recruiting | 4 | 312 | | Use of iron isomaltose on a simplified scale, intravenous infusion over 15 minutes ;Polysaccharide iron complex 0.3g was used once a day for 4 months after hemoglobin returned to normal. | Hongci Hematology Branch of the First Affiliated Hospital of Soochow University; Hongci Hematology Branch of the First Affiliated Hospital of Soochow University, Bethune Foundation | Iron Deficiency Anemia | | | | |
| Recruiting | 4 | 310 | Europe | Ferric Derisomaltose 100 MG/ML, Monofer, Sodium chloride, Placebo | dr. P. Noordzij, Pharmacosmos A/S | Iron Deficiency Anemia | 09/25 | 12/25 | | |
ChiCTR2400083168: Application Study of Iron Isomaltoside in Patients with Iron Deficiency Anemia Six Months After Weight Loss Surgery |
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| Not yet recruiting | 4 | 200 | | Iron isomaltoside injection (MonoFer), administered by intravenous drip, referring to the simplified scale method of administration in the product insert. Note: The maximum single dose of ferric isomaltoside is 20 mg/kg, and according to the simplified scale, a second infusion is required every other week if a single underdose is made up.; Iron Polysaccharide Complex (NIFEREX), 150mg/day for 8 weeks by oral | The Third People's Hospital of Chengdu; Bethune Foundation, Bethune Foundation | Iron Deficiency Anemia After Weight Loss Surgery | | | | |
NCT05719376: The Effect of Intravenous Iron Therapy and Erythropoiesis-stimulation Agent Combination on Renal Transplant Outcomes |
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| Not yet recruiting | 4 | 302 | RoW | Monofer (experimental), control group | Yonsei University | Kidney Failure, Chronic | 05/26 | 06/26 | | |
