No Longer Available

N/A

US

Allogeneic Pancreatic Islet Cells, Sirolimus, Basiliximab, Tacrolimus, Antibacterial, Antifungal, and Antiviral Prophylaxis, Trimethoprim/sulfamethoxazole, Septra SS, Clotrimazole, Mycelex Troche, Valganciclovir, Valcyte, Heparin, Anticoagulation and Hematological Agent, Enoxaparin, Lovenox; Anticoagulation and Hematological Agent, Pentoxifylline, Aspirin, ASA

National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Type 1 Diabetes Mellitus

 

 

Completed

N/A

178

NA

FKBP12 expression, sirolimus

First People's Hospital of Hangzhou

Hepatocellular Carcinoma, Liver Transplantation, Prognosis

01/21

08/23

Recruiting

N/A

30

 

mTOR inhibitors

Chinese PLA General Hospital; Chinese PLA General Hospital, Beijing Municipal Science and Technology Committee; The National Basic Research Program of China (973 Program)

Tuberous Sclerosis Complex

 

 

Not yet recruiting

N/A

50

 

Use sirolimus for treatment

Children‘s Hospital of Fudan University; Children’s Hospital of Fudan Universiy, Children's Hospital of Fudan University

refractory vascular malformations

 

 

Recruiting

N/A

70

 

Cyclosporine ;cyclosporine combined with sirolimus

Renal Division, Peking University First Hospital; Renal Division, Peking University First Hospital, Huabei Pharmaceutical Company.

idiopathic membranous nephropathy

 

 

Not yet recruiting

N/A

80

 

glucocorticoid ;glucocorticoid ＆ Ciclosporin ;glucocorticoid ＆ rapamycin ;rapamycin

Tianjin Medical University General Hospital; Tianjin Medical University General Hospital, Clinical Founding

Autoimmune

 

 

Recruiting

N/A

20

 

cyclophosphamide and sirolimus

The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical Universit, None

lupus nephritis

 

 

Recruiting

N/A

305

 

Rapamycin stent implantation

Zhoupu Hospital of New Pudong District in Shanghai City; Zhoupu Hospital of New Pudong District in Shanghai City, Key discipline group of New Pudong District

Coronary heart disease

 

 

Recruiting

N/A

20

 

sirolimus

The First Affiliated Hospital of China Medical University; The First Affiliated Hospital of China Medical University, Self-raised

Systemic Sclerosis

 

 

Recruiting

N/A

25

Europe

Tacrolimus（FK506）

Fondazione IRCCS Policlinico San Matteo di Pavia

Heart Transplant Failure

06/22

06/25

Not yet recruiting

N/A

10

 

Rapamycin

The First Medical Center of PLA General Hospital; The First Medical Center of PLA General Hospital, self-finance

Autism Spectrum Disorder

 

 

Not yet recruiting

N/A

108

 

Oral sirolimus treatment

Ninth People's Hospital, Shanghai JiaoTong University School of Medicine; Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Self-rised

Low-flow vascular malformation

 

 

Not yet recruiting

N/A

78

 

given sirolimus capsules combined with ciclosporin(CsA) or tacrolimus(FK506) capsules

The Hematology Department of Xinqiao Hospital, the Second Affiliated Hospital of The Army Medical University; Level of the institution：, Army medical university clinical innovation training program

Steroid- ineffective/dependent cGVHD

 

 

Completed

N/A

1300

Europe

University Hospital, Geneva, Insel Gruppe AG, University Hospital Bern

Coronary Artery Disease, Acute Coronary Syndrome

04/23

10/23

Recruiting

N/A

20

RoW

Autologous regenerative islet transplantation for insulin-dependent diabetes mellitus

Shanghai Changzheng Hospital

Diabetes

06/23

12/23

Recruiting

N/A

600

US

Sirolimus, Rapamune, rapamycin, Everolimus, Afinitor

University of Cincinnati, Rare Diseases Clinical Research Network, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI), The LAM Foundation

Lymphangioleiomyomatosis

07/24

07/25

Recruiting

N/A

700

US

Sirolimus

National Institute of Mental Health (NIMH)

Schizophrenia

 

 

Recruiting

N/A

10

RoW

Sirolimus 1Mg Oral Tablet

Sohag University

Microcystic Lymphatic Malformation, Combined Vascular Malformation, Vascular Malformations

09/24

09/24

Recruiting

N/A

10

Europe

Exercise, Insulin infusion, Placebo, Rapamycin

University of Copenhagen, Danish Diabetes Academy

Insulin Sensitivity

06/29

06/29

Recruiting

N/A

120

 

Corticosteroid ;rapamycin ;hormone in combination with propranolol ;rapamycin in combination with propranolol ;hormone in combination with vincristine ;Rapamycin in combination with hormones

Beijing Children's Hospital Affiliated to Capital Medical University; Anhui Children's Hospital, self-financing

Kaposi form hemangio endothelioma

 

 

Recruiting

N/A

70

Europe

SELUTION SLR DCB, Paclitaxel DCB

University Hospital, Essen

Peripheral Arterial Disease, Flow-mediated Dilation, Drug Eluting Balloon, Infrainguinal Peripheral Arterial Disease

04/24

04/24

Not yet recruiting

N/A

4

Europe

Lymphapheresis

Assistance Publique - Hôpitaux de Paris

Kidney Transplantation, Liver Transplantation

04/24

04/24

Recruiting

N/A

30

RoW

ABLUMINUS DES drug eluting stent

Concept Medical Inc.

Peripheral Artery Disease, Arterial Disease of Legs, Atherosclerosis

06/24

12/24

Recruiting

N/A

300

Europe, US, RoW

SELUTION SLR™ 018 DEB, Plain (Uncoated) Balloon Angioplasty (PTA)

Peripheral Arterial Disease, Superficial Femoral Artery Stenosis

12/24

12/29

Not yet recruiting

N/A

60

 

oral sirolimus

Beijing Children’s Hospital, Capital Medical University (National Center for Children’s Health, China); Beijing Children’s Hospital, Capital Medical University (National Center for Children’s Health, China), Beijing Natural Science Foundation (No.7222058)

PIK3CA-Related Overgrowth Spectrum（PROS）

 

 

Not yet recruiting

N/A

10

 

Gene detection and sirolimus therapy

Fujian Maternal and Child Health Hospital; Fujian Maternal and Child Health Hospital, Fujian Province Science and Technology Innovation Joint Fund Project

Vascular Malformations

 

 

Recruiting

N/A

174

RoW

Children's Hospital of Fudan University

Kaposiform Hemangioendothelioma

03/26

03/28

Not yet recruiting

N/A

120

 

sirolimus; nothing; nothing

Zhongshan Hospital, Fudan University; Zhongshan Hospital, Fudan University, Zhongshan Hospital，Fudan University

lymphangioleiomyomatosis

 

 

Not yet recruiting

N/A

500

 

Non-intervention; Non-intervention

Zhong Shan Hospital, Fudan University; Zhong Shan Hospital, Fudan University, Clinical Research Special Project of Shanghai Municipal Health Commission

Liver transplant

 

 

Recruiting

N/A

180

 

Cyclosporine ± glucocorticoid; Rapamycin and roxastat; Rapamycin and roxastat; Rapamycin

Suzhou Hongci Blood Disease Hospital; Suzhou Hongci Blood Disease Hospital, Self-financing

acquired pure red cell aplasia