Online Trial Tracker - Larvol Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

sirolimus / Generic mfg.

NCT00672243: Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme

Completed

Erlotinib + sirolimus, sirolimus - Rapamune, erlotinib - Tarceva - OSI-774

Duke University, Genentech, Inc., OSI Pharmaceuticals

Glioblastoma, Gliosarcoma

09/08

12/09

NCT00043979: Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas

Completed

F-18 Fluorodeoxyglucose, FDG, therapeutic allogeneic lymphocytes, cyclophosphamide, Cytoxan, cyclosporine, Sandimmune, doxorubicin hydrochloride, Adriamycin, etoposide, Vepesid, fludarabine phosphate, Fludara, melphalan, Alkeran, prednisone, Deltasone, sirolimus, Rapamune, tacrolimus, Prograf, vincristine sulfate, Oncovin, peripheral blood stem cell transplantation, PBSCT, Filgrastim, Peripheral Blood Stem Cell donation

National Cancer Institute (NCI)

Sarcoma

05/09

12/11

OCR, NCT00743509: A Phase II Study of Oral Cyclophosphamide and Sirolimus () in Advanced Sarcoma

	Data-ASCO
	Jun 2011 - Jun 2011: Data-ASCO

Completed

Cyclophosphamide and Sirolimus, Sirolimus (rapamycin, Rapamune)

University of Michigan Rogel Cancer Center

Osteosarcoma

04/10

09/12

2012-001106-26: TRIAL PHASE II MULTICENTER FOR CANCER PATIENTS DIAGNOSED WITH OSTEOSARCOMA WITH METASTASIS WHO HAVE ALREADY BEEN TREATED PREVIOUSLY ESTUDIO FASE II MULTICENTRICO PARA PACIENTES DIAGNOSTICADOS DE CANCER TIPO OSTEOSARCOMA CON METASTASIS QUE YA HAN SIDO TRATADOS PREVIAMENTE

Ongoing

Europe

Concentrate and solvent for solution for infusion, Oral solution, GEMCITABINE, RAPAMUNE

JAVIER MARTÍN BROTO, Dirección General de Farmacia y Productos Sanitarios del Ministerio de Sanidad, Política Social e Igualdad

Patients diagnosed with metastatic osteosarcoma cancer types that have been treated with chemotherapy and have active disease that permits to receive this treatment combination. Pacientes diagnosticados de osteosarcoma metastásico que han sido tratados con quimioterapia y tienen enfermedad que permite recibir esta combinación de tratamiento., Patients with metastatic osteosarcoma cancer that have been treated with standard chemotherapy and have active disease requiring treatment. Pacientes diagnosticados de cáncer tipo osteosarcoma metastásico que han sido tratados y tienen enfermedad activa, necesitando recibir tratamiento para su enfermedad., Diseases [C] - Cancer [C04]

GEIS-29, NCT02429973: Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma

Completed

Europe

Gemcitabine plus rapamycin

Broto, Javier Martín, M.D.

Osteosarcoma

12/14

04/15

NCT01842594: A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma

Terminated

RoW

Sirolimus and hydroxychloroquine

Shin Kong Wu Ho-Su Memorial Hospital

Sarcoma

01/15

NCT02987959: Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas

Terminated

TAK-228, MLN0128

Fox Chase Cancer Center

Soft-tissue Sarcoma

01/19

07/20

COSYMO, NCT02821507 / 2013-005155-32: Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma

Completed

Europe

sirolimus and cyclophosphamide

Leiden University Medical Center

Conventional Chondrosarcoma, Myxoid Liposarcoma, Mesenchymal Chondrosarcoma, Dedifferentiated Chondrosarcoma

12/21

HopES, NCT03778996: SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma

Active, not recruiting

Combination metyrosine-derivative, low-dose methoxsalen, phenytoin and sirolimus (MPS), SM-88

Sarcoma Oncology Research Center, LLC, Tyme, Inc

Sarcoma, Ewing, Sarcoma

12/24

03/25

NCT02790515: Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Recruiting

Anti-thymocyte globulin (rabbit), Thymoglobulin®, rabbit ATG, Blinatumomab, Blincyto, Cyclophosphamide, Cytoxan, Fludarabine, Fludara, G-CSF, Filgrastim, Neupogen®, Melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran, Mesna, Mesnex, Rituximab, Rituxan™, Tacrolimus, FK506, Prograf®, Protopic®, Thiotepa, Thioplex® by Immunex, TESPA, TSPA, HPC,A Infusion, Transplant, CliniMACS, Cell Selection System, Sirolimus, Rapamycin, Rapamune®

St. Jude Children's Research Hospital

Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myeloid Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)

07/24

07/25

NCT01684449: Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma

	ASCO 2014
	May 2014 - May 2014: ASCO 2014

Completed

1/2

Europe

Gemcitabine + Rapamycin

Grupo Espanol de Investigacion en Sarcomas

Advanced Soft Tissue Sarcoma

05/13

12/13

SARC023, NCT02008877: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Completed

1/2

ganetespib, STA-9090, Sirolimus, Rapamycin

Sarcoma Alliance for Research through Collaboration, Synta Pharmaceuticals Corp., United States Department of Defense

Malignant Peripheral Nerve Sheath Tumors (MPNST), Sarcoma

04/18

07/18

NCT01265030: A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis

Completed

1/2

Sirolimus, Rapamune®, Rapamycin

MaineHealth, Desmoid Tumor Research Foundation, Pfizer

Desmoid Tumor

12/21



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