| bupropion ER / Generic mfg. |
| Completed | 4 | 347 | US | Bupropion Hydrochloride Extended-release, Extended-release Venlafaxine | GlaxoSmithKline | Depressive Disorder, Major, Major Depressive Disorder (MDD) | 05/05 | 05/05 | | |
NCT00234195: Wellbutrin XL, Major Depressive Disorder and Breast Cancer |
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| Completed | 4 | 25 | US | bupropion extended release (Wellbutrin XL) | Thomas Jefferson University, GlaxoSmithKline | Breast Cancer, Major Depressive Disorder | | 01/07 | | |
| Completed | 4 | 15 | US | Wellbutrin XL | Indiana University School of Medicine | Depression, Side Effects, Sexual Dysfunction, Apathy | | 11/07 | | |
| Completed | 4 | 18 | US | bupropion XL, Wellbutrin XL, Placebo | St. Luke's-Roosevelt Hospital Center, GlaxoSmithKline | Dysthymic Disorder | 05/08 | 06/08 | | |
NCT00429169: Paroxetine/Bupropion in Suicide Attempters/Ideators With Major Depression |
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| Terminated | 4 | 101 | US | Paroxetine, Paxil CR, Bupropion, Wellbutrin XL | New York State Psychiatric Institute, National Institute of Mental Health (NIMH) | Depression | 01/10 | 01/13 | | |
2009-016953-16: Depressions-Spektrums-Störung und differenzielle Effekte neuerer Antidepressiva auf die Verkehrssicherheit |
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| Ongoing | 4 | 120 | Europe | Cipralex, Solvex, Remergil, Elontril, Valdoxan, Tablet, Cipralex, Solvex, Remergil, Elontril, Valdoxan | Inn-Salzach-Klinikum gGmbH | Spectrum of depressive diseases, ICD-10: F32.x, F33.x | | | | |
NCT01477931: Interventional Study of Wellbutrin XL in Major Depressive Disorder With Atypical Features |
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| Completed | 4 | 50 | RoW | Bupropion extended release, Wellbutrin XL | Chi-Un Pae, GlaxoSmithKline | Depressive Disorder, Major | 07/11 | 09/11 | | |
NCT00917059: Personalized Indicators for Predicting Response to SSRI Treatment in Major Depression (The PRISE-MD Study) |
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| Completed | 4 | 172 | US | Escitalopram, Lexapro, Bupropion XL, Wellbutrin XL | University of California, Los Angeles, National Institute of Mental Health (NIMH) | Depression | 05/12 | 05/12 | | |
NCT02173886: A Comparison of Sustained and Extended Release Bupropion Following Bariatric Surgery |
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| Completed | 4 | 20 | US | Bupropion SR and XL | North Dakota State University, Neuropsychiatric Research Institute, Fargo, North Dakota | Roux en Y Gastric Bypass | 02/15 | 02/15 | | |
NCT01748955: Paroxetine/Bupropion in Depression With Suicide Attempt or Thoughts: fMRI Study |
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| Completed | 4 | 15 | US | Paroxetine CR for Major Depressive Episode, Paxil CR, Bupropion XL for Major Depressive Episode, Wellbutrin XL | New York State Psychiatric Institute, National Institute of Mental Health (NIMH) | Depression, Suicidal Ideation | 03/15 | 03/15 | | |
NCT02638129: Naltrexone/Bupropion Cardiovascular Outcomes Study |
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| Terminated | 4 | 67 | US | Naltrexone HCl/Bupropion HCl ER, Contrave, Placebo | Orexigen Therapeutics, Inc | Obesity, Cardiovascular Diseases | 06/16 | 06/16 | | |
| Completed | 4 | 74 | US | Bupropion XL 300, Wellbutrin, Par, Mylan, Valeant | Washington University School of Medicine | Major Depressive Disorder | 08/16 | 08/16 | | |
NCT02616315: Efficacy of Naltrexone HCl/Bupropion HCl Extended Release Versus Placebo for Treatment of Weight Regain in Participants Post Bariatric Surgery |
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| Withdrawn | 4 | 0 | US | Naltrexone HCl/Bupropion HCl Placebo, Naltrexone HCl/Bupropion HCl | Takeda | Weight Regain Post Bariatric Surgery | 10/17 | 12/17 | | |
| Completed | 4 | 95 | US | Escitalopram, Lexapro, Bupropion XL, Wellbutrin XL | Vanderbilt University Medical Center | Major Depressive Disorder | 08/20 | 08/20 | | |
| Terminated | 4 | 18 | US | Escitalopram, Lexapro, Bupropion, Wellbutrin XL | University of Texas Southwestern Medical Center | Depression | 03/22 | 03/22 | | |
| Active, not recruiting | 4 | 69 | US | Weight Management Program (WMP), Traditional care, Phentermine / Topiramate Extended Release Oral Capsule, naltrexone/bupropion extended-release, liraglutide 3.0 mg, Orlistat | The Cleveland Clinic | Type 2 Diabetes, Obesity | 08/22 | 06/23 | | |
NCT04352101: Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits |
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| Completed | 4 | 18 | US | Bupropion XL, Wellbutrin, Escitalopram, Lexapro | Emory University, National Institute of Mental Health (NIMH) | Major Depression | 07/22 | 07/22 | | |
NCT04098874: Bupropion for the Prevention of Postpartum Smoking Relapse |
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| Recruiting | 4 | 200 | US | Bupropion Extended Release Oral Tablet, Placebo oral tablet | University of Minnesota, National Institute on Drug Abuse (NIDA) | Postpartum Smoking Relapse | 12/24 | 08/25 | | |
NCT04604509: Nicotine Replacement Therapy, Counseling, Varenicline, and Bupropion for Smoking Cessation, the PISCES I Trial |
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| Recruiting | 4 | 2010 | US | Bupropion Hydrochloride Controlled-release, Bupropion HCl Controlled-release, Bupropion HCl Extended Release, Bupropion Hydrochloride Extended-Release, Forfivo XL, Wellbutrin SR, Wellbutrin XL, Zyban, Nicotine Replacement, Nicotine Replacement Therapy, NRT, Questionnaire Administration, Tobacco Cessation Counseling, Varenicline, Champix, Chantix, CP-526555 | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Cigarette Smoking-Related Carcinoma | 12/28 | 12/28 | | |
NCT06098079: Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) |
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| Recruiting | 4 | 8600 | US | Naltrexone-Bupropion (NB) Combination, Placebo | Currax Pharmaceuticals | Obesity | 01/29 | 07/29 | | |
