Inflammation  >>  Pegasys (pegylated interferon α -2a)  >>  Phase N/A
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65 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pegasys (pegylated interferon α -2a) / Roche
NCT00188240: Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy

Unknown status
N/A
200
Canada
Pegasys; Copegus.
University Health Network, Toronto
Hepatitis C, Hepatitis B
 
 
NCT00514111: Factors Associated to Success of Hepatitis C Therapy

Completed
N/A
100
RoW
pegylated-interferon, conventional-interferon, ribavirin, Pegasys, PegIntron, Ribavirin
UPECLIN HC FM Botucatu Unesp
Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
07/08
12/08
NCT00543244: Early Prediction of Successful Treatment for Chronic Hepatitis C Virus Infection in Taiwan

Unknown status
N/A
300
RoW
Pegylated interferon alfa and ribavirin, Pegasys plus Robatrol, Peg-Intron plus Rebetol
National Taiwan University Hospital, National Science Council, Taiwan
Chronic Hepatitis C
10/08
12/08
NCT02850289: APPROACH Study: Quality of Life and Outcomes Assessment in Participants With Chronic Hepatitis C (CHC) Treated With Pegylated Interferon (PEG-IFN) Alfa-2a and Ribavirin

Completed
N/A
385
Canada
Pegylated interferon (PEG-INF) alfa-2a, PEGASYS, Ribavirin, COPEGUS
Hoffmann-La Roche
Hepatitis C, Chronic
10/08
10/08
DICO, NCT00909129: Interactions of Hepatitis C Viral (HCV) Dynamics and Immune Activation in HIV Coinfected Patients During HCV Treatment

Completed
N/A
25
Europe
pegylated interferon-alpha (Pegasys), Pegasys (interferon), ribavirin (COPEGUS), COPEGUS (RIBAVIRIN)
Karolinska Institutet, The Swedish Research Council, Hoffmann-La Roche
Human Immunodeficiency Virus, Chronic Hepatitis C
 
 
NCT00842205: Role of Heme Oxygenase in the Pathogenesis of Hepatocellular Injury in Chronic Hepatitis C Virus (HCV) Infection

Unknown status
N/A
150
Europe
pegylated interferon, Pegasys, Pegintron, Ribavarin, Copegus, Rebetol
Charles University, Czech Republic, IGA MZ, Czech Republic
Chronic HCV Infection, Nonalcoholic Steatohepatitis
06/09
12/09
NCT00571714: Pilot Comparison of Standard Antiviral Therapy With and Without 12 Weeks of Betaine in Genotype 1 Naive Patients

Withdrawn
N/A
0
NA
Peginterferon alpha-2a and ribavirin, Pegasys, Copegus, Peginterferon alpha-2a , ribavirin and betaine, Copegas
University of Nebraska
Chronic Hepatitis C
03/10
03/10
NCT00700401: POTENTE Study: A Study of Early Virological Response in Naive Patients With Chronic Hepatitis C, Genotype 2 or 3, Treated With PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Copegus (Ribavirin).

Completed
N/A
262
RoW
peginterferon alfa-2a [Pegasys], ribavirin [Copegus]
Hoffmann-La Roche
Hepatitis C, Chronic
11/10
11/10
NCT01066793: PROPHESYS 2: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Checkmark Data-EASL
Apr 2012 - Apr 2012: Data-EASL
Completed
N/A
2343
Europe
Peginterferon alfa-2a [Pegasys], Peginterferon alfa-2b [PegIntron®]
Hoffmann-La Roche
Hepatitis C, Chronic
03/11
05/11
NCT01464008: The Predictive Value of On-treatment Virological Response for Sustained Virological Response in Chronic Hepatitis C

Completed
N/A
297
RoW
Pegylated interferon alfa-2a and ribavirin, Pegasys®; Roche, Basel, Switzerland
Beijing Ditan Hospital
Chronic Hepatitis C
05/11
09/11
NCT02726022: A Quality of Life Study of Peginterferon-Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C and Persistently Normal Alanine Transaminase (ALT) Levels

Completed
N/A
114
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
07/11
07/11
NCT01070550: PROPHESYS 1: An Observational Study on Predictors of Response in Treatment-naïve Patients With Chronic Hepatitis C Virus (HCV)Treated With Pegasys (Peginterferon Alfa-2a)

Checkmark Data-EASL
Apr 2012 - Apr 2012: Data-EASL
Checkmark Data-AASLD
Oct 2011 - Oct 2011: Data-AASLD
Completed
N/A
4680
Canada, Europe, RoW
Peginterferon alfa-2a (Pegasys®)
Hoffmann-La Roche
Hepatitis C, Chronic
07/11
07/11
NCT01066819: PROPHESYS 3: Observational Study on Predictors of Response in Patients With Treatment-naïve Chronic Hepatitis C Initiated on Treatment With Pegasys (Peginterferon Alfa-2a) or Peginterferon-alfa-2b

Completed
N/A
1656
US
Peginterferon alfa-2a [Pegasys], Peginterferon alfa-2b [PegIntron®]
Hoffmann-La Roche
Hepatitis C, Chronic
08/11
08/11
MEN_EPID, NCT01402583: Menopause is a Critical Factor in Determining Failure of Antiviral Therapy in Women With Chronic Hepatitis C

Completed
N/A
1000
Europe
PEG IFN/Ribavirin, Pegylated IFN 2a Pegasys, Pegylated IFN 2b PegIntron, Copegus, Rebetol
Prof. Facchinetti Fabio, Merck Sharp & Dohme LLC
Chronic Hepatitis C
08/11
09/11
NCT00724451: Observational Study Assessing Chronic Hepatitis C Management in Clinical Practice in Italy (Study P05488 AM1)

Completed
N/A
1128
Europe
Peginterferon alfa-2b, SCH 054031, PegIntron, Ribavirin, SCH 018908, Copegus, Rebetol, Virazole, RBV, Peginterferon alfa-2a, Pegasys
Merck Sharp & Dohme LLC
Hepatitis C, Hepatitis C, Chronic
10/11
10/11
NCT00361179: Long Term Effects of Peginterferon Alfa-2a Plus Ribavirin for Chronic Hepatitis C/B Co-Infection and Chronic Hepatitis C

Completed
N/A
320
RoW
National Taiwan University Hospital, Hoffmann-La Roche
Coinfection With Hepatitis B Virus and Hepatitis C Virus, Monoinfection With Hepatitis C Virus
 
12/11
NCT01311947: Hepatitis B Virus Mutants and the Therapeutic Effect of Peginterferon Alfa-2a in HBeAg-Positive Chronic Hepatitis B

Completed
N/A
103
RoW
Peginterferon alfa-2a, Pegasys
China Medical University Hospital
Hepatitis B, Chronic
03/12
03/12
NCT01734018: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive or HBeAg-Negative Chronic Hepatitis B

Completed
N/A
50
Europe
Hoffmann-La Roche
Hepatitis B, Chronic
08/12
08/12
NCT01645969: A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265

Completed
N/A
65
RoW
Hoffmann-La Roche
Hepatitis B, Chronic
10/12
10/12
NCT00788918 / 2007-005707-18: Study of Cerebral Function in Patients With Chronic Hepatitis C Infection (HCV/CNS)

Completed
N/A
100
Europe
Interferon and ribavirin, Pegasys (ATC Code: L03AB11) and Copegus (ATC Code: J05AB04)
Aarhus University Hospital
Hepatitis C, Chronic, Cognition Disorders, Fatigue Syndrome, Chronic, Major Depressive Disorder
11/12
11/12
NCT01283074: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas)

Completed
N/A
107
Europe
Hoffmann-La Roche
Hepatitis B, Chronic
11/12
11/12
NCT01471535: HBsAg Clearance in Inactive Chronic HBsAg Carriers After Interferon Treated

Completed
N/A
20
RoW
Pegylated interferon alfa-2a, Pegasys®; Roche, Basel, Switzerland
Beijing Ditan Hospital
Chronic Hepatitis B
12/12
12/12
NCT01705704: A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

Completed
N/A
269
Europe, RoW
Hoffmann-La Roche
Hepatitis B, Chronic
02/13
02/13
NCT02113631: Comparative Effectiveness and Tolerability of Boceprevir vs Telaprevir

Completed
N/A
50
US
Telaprevir, INCIVEK, Boceprevir, Victrelis, Peg-IFN, Peg-Interferon alfa-2a, Pegasys, Ribavirin, Copegus
Louis Stokes VA Medical Center
Hepatitis C, Chronic, Cirrhosis
04/13
04/13
NCT01886300: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Positive Chronic Hepatitis B in Vietnam

Terminated
N/A
16
RoW
Hoffmann-La Roche
Hepatitis B, Chronic
05/13
05/13
NCT01200225: An Observational Study on The Impact of Insulin Resistance on Sustained Virological Response in Patients With Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin)

Completed
N/A
1155
Europe
Hoffmann-La Roche
Hepatitis C, Chronic
06/13
06/13
Perseo, NCT01900886: Epidemiological Study to Evaluate Personality Disorders in Prison Populations in Treatment for Hepatitis C

Checkmark AASLD 2013: PERSEO
Oct 2013 - Oct 2013: AASLD 2013: PERSEO
Unknown status
N/A
263
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Grupo de Enfermedades Infecciosas de la Sociedad Española de Sanidad Penitenciaria
Hepatitis C, Chronic, Personality Disorders in Prison
06/13
12/13
NCT01625793: Inflammation, Stress & Social Behavior: Using Ecological Assessments & Model Systems to Enhance Relevance to Health Outcomes

Withdrawn
N/A
0
US
Interferon-alpha, Pegintron®, Schering Plough, PEGASYS®, Roche
University of Arizona, Emory University, National Center for Complementary and Integrative Health (NCCIH)
Hepatitis C
07/13
07/13
NCT02106156: Observational Study Evaluating the Quality of Pegylated Interferon Alfa-2a and Ribavirin Treatment for Chronic Hepatitis C in Cooperation With the BNG (Association of German Resident Gastroenterologists)

Completed
N/A
10228
Europe
Pegylated interferon alfa-2a, Pegasys®, Ribavirin, Copegus®
Hoffmann-La Roche
Chronic Hepatitis C
09/13
09/13
NCT01794234: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis B Who Have Failed Antiviral Treatment With Nucleoside (Nucleotide) Analogues

Terminated
N/A
44
Europe
Hoffmann-La Roche
Hepatitis B, Chronic
09/13
09/13
ChiCTR-TRC-12002116: A multi-center randomized controlled clinical trial on treatment of chronic hepatitis C using Vitamin D combine pegylated interferon + ribavirin

Completed
N/A
200
 
vitamin D + peg-INF-alpha-2a ;peg-INF-alpha-2a
Department of Infectious Deases of First Teaching Hospital of Xinjiang Medical University; Department of Infectious Deases of First Teaching Hospital of Xinjiang Medical University, Roche China (Shanghai)
Hepatitis C
 
 
NCT01726400: In Hepatitis C Patients Treated With Interferon and Ribavirin, Does Hepcidin Contribute to Treatment Induced Anaemia

Completed
N/A
15
RoW
Pegylated interferon alpha, pegasys, pegatron, Ribavirin, Copegus, Rebetol, Ribasphere, Vilona, Virazole
Fremantle Hospital and Health Service
Hepatitis C
01/14
07/14
NCT02557646: An Observational Study to Assess the Effect of Cumulative Ribavirin Dose in Participants With Chronic Hepatitis C

Completed
N/A
697
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
03/14
03/14
NCT01508130: An Observational Study of Peginterferon (e.g. Pegasys)-Based Direct Acting Antiviral Triple Therapy in Patients With Chronic Hepatitis C Genotype 1

Completed
N/A
672
US
Hoffmann-La Roche
Hepatitis C, Chronic
03/14
03/14
OPTIM, NCT01884402: Observational,Prospective Study to Develop and Validate a Prognostic Tool to Optimize Therapy in Patients With HCV G1/4

Completed
N/A
770
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Hepatitis C, Chronic
05/14
08/14
NCT02556307: A Study of the Effectiveness of Peginterferon Alfa-2a (Pegasys) and Ribavirin Treatment in Slovenian Hepatitis C (HCV) Patients

Completed
N/A
270
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
07/14
07/14
NCT01639547: Sustained Virological Response (SVR)Rate of Pegasys Plus Ribavirin in Patients With Chronic Hepatitis C

Terminated
N/A
410
RoW
Peginterferon alfa-2a plus Ribavirin, PEGASYS® plus ROBATROL®
Chang Gung Memorial Hospital
Chronic Hepatitis C
07/14
07/14
NCT01392742: An Observational Study on Predictive Factors of Response in Patients With Chronic Hepatitis C Treated With Pegasys (Peginterferon Alfa-2a) and Ribavirin

Completed
N/A
443
Europe
Hoffmann-La Roche
Hepatitis C, Chronic
07/14
07/14
NCT01531166: A Cohort Study in Korean Patients With Chronic Hepatitis B (CHB) Receiving Pegylated Interferon

Completed
N/A
500
RoW
pegylated Interferon-alpha 2a, Pegasys
Yonsei University
Chronic Hepatitis B
08/14
10/14
NCT01667432: An Observational Study of Peginterferon Alfa-2a (PEGASYS®) in Patients With HBeAg Positive or HBeAg Negative Chronic Hepatitis B

Completed
N/A
141
Europe
Peginterferon alfa-2a, PEGASYS®, RO0258310
Hoffmann-La Roche
Hepatitis B, Chronic
08/14
08/14
PEGHOPE, NCT01416610: An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Copegus (Ribavirin) in Participants With Chronic Hepatitis C (CHC), Genotype 2, 3, 1 or 4, Undergoing Opioid Maintenance Therapy

Completed
N/A
88
Europe
Hoffmann-La Roche
Hepatitis C, Chronic
10/14
10/14
NCT01011738: An Observational Cohort Study in Patients With Chronic Hepatitis B Receiving Pegasys

Completed
N/A
1842
Europe, RoW
Hoffmann-La Roche
Hepatitis B, Chronic
11/14
11/14
NCT01855997 / 2013-001141-14: A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide Analogue

Completed
N/A
1669
Europe, RoW
Peg-IFN alfa-2a, Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
11/14
11/14
NCT02515279: An Observational Study of Peginterferon Alfa-2a Plus Ribavirin for Hepatitis C Virus (HCV) Infection in Austria

Completed
N/A
463
Europe
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C
12/14
12/14
NCT01750216: An Observational Study of Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) on Predictive Values of RVR on Sustained Virological Response in Different Stages of Liver Fibrosis in Treatment-Naïve Patients With Chronic Hepatitis C Genotype 1

Completed
N/A
196
Europe
Hoffmann-La Roche
Hepatitis C, Chronic
01/15
01/15
NCT01861444: An Observational Study on the Prevalence of Chronic Hepatitis D in Romania and the Efficacy of Treatment With Pegasys (Peginterferon Alfa-2a)

Terminated
N/A
45
Europe
Hoffmann-La Roche
Hepatitis D, Chronic
03/15
03/15
NCT02118597: An Observational Study Examining the Use of Triple Combination Therapy With Boceprevir, Peginterferon Alfa-2a and Ribavirin in the Re-Treatment of Chronic Hepatitis C Patients

Terminated
N/A
19
Europe
Boceprevir, Victrelis, Simeprevir, Olysio, Pegylated Interferon (Peginterferon) Alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
05/15
05/15
NCT00747539: Brain Deficits in HIV/HCV Coinfected People Before and After Anti-HCV Therapy

Completed
N/A
330
US
Pegylated interferon alfa and ribavirin (PEG-IFN/RBV), Pegasys
University of California, Los Angeles, National Institute of Mental Health (NIMH)
HIV, Hepatitis C, Infections
06/15
06/15
NCT01798576: An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Ribavirin Based Regimens in Patients With Chronic Hepatitis C With Previous Treatment Failure

Terminated
N/A
282
Europe
Pegylated Interferon alfa-2a, Peginterferon alfa 2A, Ribavirin
Hoffmann-La Roche
Hepatitis C, Chronic
06/15
06/15
STANDART, NCT01609049: An Observational Study of Peginterferon Alfa-2a in Combination With Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis

Completed
N/A
1496
RoW
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
06/15
06/15
NCT01447446: An Observational Study on Dual And Triple Therapies Based on Peginterferon Alfa (e.g. Pegasys) in Patients With Chronic Hepatitis C

Completed
N/A
4442
Europe, RoW
Peg-IFN Alfa-2a, Peg-IFN Alfa-2b, Ribavirin, Boceprevir, Telaprevir
Hoffmann-La Roche
Hepatitis C, Chronic
07/15
07/15
NCT01659567: A Study of Predictors of the Effectiveness of Pegylated Interferon in a Cohort of Participants With Hepatitis C

Completed
N/A
516
RoW
Pegylated Interferon Alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
10/15
10/15
NCT01604291: An Observational Study of Dual and Triple Therapies Based on Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C

Completed
N/A
991
RoW
Hoffmann-La Roche, Clalit Health Services
Hepatitis C, Chronic
02/16
02/16
NCT02201407: An Observational Study in Participants With Chronic Hepatitis B (CHB) Receiving Therapy With Peginterferon Alfa-2a 40 Kilodaltons (kD) (PEGASYS) - The PRO B Study

Completed
N/A
50
RoW
Peginterferon alfa-2a, PEGASYS
Hoffmann-La Roche
Hepatitis B, Chronic
04/17
04/17
NCT01730508: An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis B

Completed
N/A
978
RoW
Pegylated Interferon Alfa (Peginterferon Alfa), Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
06/17
06/17
NCT01679834: An Observational Study of Pegasys in Dual- or Triple-Therapy in Patients With Chronic Hepatitis C

Completed
N/A
7500
Europe
Hoffmann-La Roche
Hepatitis C, Chronic
07/17
07/17
LVL, NCT00973219: Hepatitis B Surface Antigen(HBsAg) Loss in Chronic Hepatitis B Patients With Low Viral Load

Completed
N/A
151
Europe
Peg-Interferon alfa 2a + Adefovir dipivoxil, Peg-Interferon alfa 2a + Tenofovir disoproxil fumarate, Pegsys®, Hepsera®, Viread®
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Hepatitis B
10/19
10/19
NCT03181113: Long-term Benefit in Chronic Hepatitis B Patients After Standard Peginterferon Alfa Therapy

Completed
N/A
473
RoW
Peginterferon Alfa-2B, pegberon, Peginterferon Alfa-2A, pegasys
Xiamen Amoytop Biotech Co., Ltd., Peking University First Hospital
Hepatitis B
09/20
09/20
NCT03957629: Optimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver Fibrosis

Recruiting
N/A
186
RoW
Tenofovir Disoproxil Fumarate, Viread, Beixin, PEG-Interferon alfa 2a, Pegasys
Third Affiliated Hospital, Sun Yat-Sen University
Hepatitis B, Liver Fibrosis
07/21
07/23
NCT03733652: Optimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B Patients

Unknown status
N/A
100
RoW
Interferon Alfa 2a, Pegasys
Third Affiliated Hospital, Sun Yat-Sen University
Chronic Hepatitis b, Efficacy, Self
09/21
12/21
NCT03920605: Optimized Treatment of Peginterferon Alfa 2a/2b in Treatment Experienced Patients With HBV Related Liver Fibrosis

Unknown status
N/A
100
RoW
Tenofovir Disoproxil Fumarate, Viread, Peginterferon Alfa-2a, Pegasys, Peginterferon Alfa-2b, Pegintron
Third Affiliated Hospital, Sun Yat-Sen University
Hepatitis B, Liver Fibrosis
10/21
12/21
HBV, NCT03919565: Optimized Treatment of Peginterferon Alfa 2a/2b in Anti-virus Treatment Naive Patients With Related Liver Fibrosis

Unknown status
N/A
120
RoW
Tenofovir Disoproxil Fumarate, Viread, Peginterferon Alfa-2a, Pegasys, Peginterferon Alfa-2b, Pegintron
Third Affiliated Hospital, Sun Yat-Sen University
Hepatitis B, Liver Fibrosis
10/21
12/21
RCAP, NCT05683548: Replicor Compassionate Access Program

Available
N/A
Europe, RoW
REP 2139-Mg, Tenofovir Disoproxil Fumarate, Viread, Pegylated interferon alpha2a, Pegasys
Replicor Inc.
Viral Hepatitis B, Viral Hepatitis D, Cirrhosis, Liver, Decompensated Cirrhosis, Ascites Hepatic, Varices, Esophageal, Hepatocellular Carcinoma
 
 
HERACLIS-BLV, NCT05928000: HEllenic Multicenter ReAl-life CLInical Study for Bulevirtide Therapy in Chronic Hepatitis D:

Recruiting
N/A
80
Europe
Bulevirtide, Entecavir, Tenofovir, Pegasys
University of Athens
Hepatitis D
11/23
12/23
NCT03771677: To Optimize the Therapeutic Pathway of Peginterferon Treatment in Patients With CHB Based on IFNA2p.Ala120Thr /ISGs.

Recruiting
N/A
400
RoW
Nucleotide Analog, Nucleotide Analogs, Interferon Alfa-2A, Pegasys
Sun Yat-sen University, First People's Hospital of Foshan, Eighth Affiliated Hospital, Sun Yat-sen University
Hepatitis B
12/23
12/24

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