Inflammation  >>  Pegasys (pegylated interferon α -2a) 
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13 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pegasys (pegylated interferon α -2a) / Roche
2015-003024-31: Protecting immune responses in patients treated with the new DAA anti hepatitis C alone or in combination with previously used medications (interferon and ribavirin) Risposte immunitarie proteggenti in pazienti trattati con i nuovi farmaci anti epatite C (nuovi DAA) da soli o in associazione con i farmaci precedentemente utilizzati (interferone e ribavirina)

Not yet recruiting
4
30
Europe
PEGINTERFERONE ALFA-2A, RIBAVIRINA, SOFOSBUVIR, LEDIPASVIR+SOFOSBUVIR, N.A., Solution for injection, Capsule, hard, Film-coated tablet, PEGASYS - 180MCG-SOLUZ. INIETTABILE-USO SOTTOCUT.-PENNA PRERIEMPITA-0.5 ML (360MCG/ML) 1 PENNA PRERIEMPITA, REBETOL - 200 MG 84 CAPSULE RIGIDE IN BLISTER, SOVALDI - 400 MG - COMPRESSA RIVESTITA CON FILM - FLACONE (HDPE) - 28 COMPRESSE, HARVONI - 90 MG/400 MG - COMPRESSE RIVESTITE CON FILM - USO ORALE - FLACONE (HDPE) - 28 COMPRESSE RIVESTITE CON FILM
AZIENDA OSPEDALIERO-UNIVERSITARIA DI PARMA, GILEAD SCIENCES SRL
CHRONIC HEPATITIS C EPATITE C CRONICA, CHRONIC HEPATITIS C EPATITE C CRONICA, Diseases [C] - Virus Diseases [C02]
 
 
NCT01727323 / 2010-021337-31: A Study to Assess the Safety, Tolerability and Efficacy of TMC435 Along With Pegylated Interferon Alpha-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hepatitis C Genotype-1 Infected Patients Co-infected With Human Immunodeficiency Virus-Type 1

Active, not recruiting
3
109
US, Canada, Europe
TMC435, Pegylated interferon alpha-2a, Ribavirin
Janssen Research & Development, LLC, Janssen R&D Ireland, Tibotec Pharmaceuticals
Hepatitis C Virus Genotype-1
08/13
08/13
D-LIVR, NCT03719313 / 2018-003167-54: Study of the Efficacy and Safety of Lonafarnib / Ritonavir With and Without Pegylated Interferon -Alfa-2a

Completed
3
407
Europe, Canada, US, RoW
Lonafarnib, EBP994, Sarasar, LNF, Ritonavir, Norvir, RTV, PEG IFN-alfa-2a, Pegasys, pegylated interferon-alfa, Placebo Lonafarnib, Placebo Ritonavir
Eiger BioPharmaceuticals
Hepatitis Delta Virus
10/22
03/23
2017-001647-12: A study to determine how safe the treatment is for subjects diagnosed with hepatitis B virus infections when combined with other treatments for hepatitis B. Subjects must have no evidence of liver damage. Un estudio para determinar la seguridad del tratamiento para los sujetos diagnosticados con infecciones por el virus de la hepatitis B cuando se combinan con otros tratamientos para la hepatitis B. Los sujetos no deben tener evidencia de daño hepático.

Ongoing
2
20
Europe
ARB-001467, Viread, Pegasys, ARB-001467, Solution for infusion, Film-coated tablet, Solution for injection in pre-filled syringe, Viread, Pegasys
Arbutus Biopharma Corporation, Arbutus Bipoharma Corporation
Hepatitis B virus e-antigen (HBeAg)-negative subjects with chronic hepatitis B virus infection (CHB) Pacientes con infección crónica por el virus de la hepatitis B (HBC) HBeAg-negativo sin cirrosis, Subjects infected with hepatitis B virus Los sujetos infectados con el virus de la hepatitis B, Diseases [C] - Virus Diseases [C02]
 
 
2019-001485-15: This study will use an investigational product (bulevirtide) for the treatment of chronic hepatitis Delta to learn the therapeutic effect, and safety of the drug in humans.

Ongoing
2
175
Europe
Bulevirtide, Lyophilisate for solution for injection, Solution for injection, Pegasys
MYR GmbH, MYR GmbH
Chronic Hepatitis Delta, Chronic Hepatitis Delta, Diseases [C] - Virus Diseases [C02]
 
 
2019-004978-26: A clinical study to evaluate efficacy, pharmacokinetics, safety, and tolerability of response-guided treatment with JNJ-73763989 + JNJ-56136379 + nucleos(t)ide analog regimen with or without pegylated interferon alpha-2a in treatment-naïve patients with HBeAg positive chronic hepatitis B virus infection.

Not yet recruiting
2
80
Europe
JNJ-73763989, JNJ-56136379, Solution for injection, Tablet, Film-coated tablet, Solution for injection in pre-filled syringe, Tenofovir disoproxil Mylan 245 mg film-coated tablets, Vemlidy 25 mg film-coated tablets, Pegasys 180 micrograms solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Sciences Ireland Unlimited Company
Chronic Hepatitis B Virus Infection, Chronic Hepatitis B Virus Infection, Diseases [C] - Virus Diseases [C02]
 
 
2021-002450-81: A Clinical Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Treatment With JNJ-73763989, Nucleos(t)ide Analogs, and Pegylated Interferon Alpha-2a in Patients With Chronic Hepatitis B Virus Infection. Estudio clínico para evaluar la eficacia, seguridad, tolerabilidad y farmacocinética del tratamiento con JNJ-73763989, análogos de nucleos(t)ido e interferón pegilado alfa-2a en pacientes con infección crónica por el virus de la hepatitis B.

Ongoing
2
102
Europe
JNJ-73763989, Solution for injection, Film-coated tablet, Solution for injection in pre-filled syringe, Entecavir Mylan 0.5 mg film-coated tablets, Viread 245 mg film-coated tablets, Vemlidy 25 mg film-coated tablets, Pegasys 180 micrograms solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research and Development LLC
Chronic Hepatitis B Virus Infection Infección crónica por el virus de la hepatitis B, Chronic Hepatitis B Virus Infection Infección crónica por el virus de la hepatitis B, Diseases [C] - Virus Diseases [C02]
 
 
2021-001033-39: A Phase 2 Study to Evaluate the Safety, Tolerability, and Efficacy of Regimens Containing VIR -2218, VIR-3434, and/or PEG-IFNα in Subjects with Chronic Hepatitis B Virus Infection

Not yet recruiting
2
260
Europe
Pegasys, VIR-2218, VIR-3434, NA, Solution for injection, Lyophilisate for solution for injection, Pegasys
Vir Biotechnology, Inc., Vir Biotechnology, Inc.
Chronic HBV infection., Chronic infection of Hepatitis B Virus., Diseases [C] - Immune System Diseases [C20]
 
 
2020-003956-34: A Clinical Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Treatment With JNJ-73763989, JNJ-56136379, Nucleos(t)ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Patients With Chronic Hepatitis B Virus Infection.

Not yet recruiting
2
50
Europe
JNJ-73763989, Solution for injection, Film-coated tablet, Solution for injection in pre-filled syringe, Viread 245 mg film-coated tablets, Vemlidy 25 mg film-coated tablets, Entecavir Mylan 0.5 mg film-coated tablets, Pegasys 180 micrograms solution for injection in pre-filled syringe
Janssen-Cilag International NV, Janssen Research and Development LLC
Chronic Hepatitis B Virus Infection, Chronic Hepatitis B Virus Infection, Diseases [C] - Virus Diseases [C02]
 
 
NCT04426968: A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B

Completed
2
96
RoW
Hepalatide 2.1mg, L47, Hepalatide 4.2mg, Hepalatide 6.3mg, placebo 2.1mg, placebo 4.2mg, placebo 6.3mg, Pegylated Interferon, Pegasys
Shanghai HEP Pharmaceutical Co., Ltd.
Hepatitis B, Chronic
11/23
11/23
NCT05244057: A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients

Recruiting
2
30
RoW
Hepalatide, L47, Placebo of Hepalatide, Placebo, Tenofovir Alafenamide Tablets, Vemlidy, Pegylated Interferon alfa 2a, Pegasys
Shanghai HEP Pharmaceutical Co., Ltd., Shanghai Tong Ren Hospital, Shanghai East Hospital
Chronic Hepatitis B
08/24
08/24
Piranga, NCT04225715 / 2019-002086-35: A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B

Active, not recruiting
2
280
Europe, Canada, US, RoW
Nucleos(t)ide (NUC), CpAM (RO7049389), TLR7 (RO7020531), siRNA (RO7445482), PEG-IFN, Pegasys®, PD-L1 LNA (RO7191863)
Hoffmann-La Roche
Hepatitis B, Chronic
08/24
01/25
RCAP, NCT05683548: Replicor Compassionate Access Program

Available
N/A
Europe, RoW
REP 2139-Mg, Tenofovir Disoproxil Fumarate, Viread, Pegylated interferon alpha2a, Pegasys
Replicor Inc.
Viral Hepatitis B, Viral Hepatitis D, Cirrhosis, Liver, Decompensated Cirrhosis, Ascites Hepatic, Varices, Esophageal, Hepatocellular Carcinoma
 
 

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