Hepatitis, Chronic  >>  Pegasys (pegylated interferon α -2a)  >>  Phase 1
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10 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pegasys (pegylated interferon α -2a) / Roche
NCT02908191: A Study in Healthy Volunteers and Patients With Chronic Hepatitis B

Completed
1a/1b
86
RoW
ABI-H0731, Placebo for ABI-H0731, Sugar pill manufactured to mimic the ABI-H0731 tablet, Entecavir, Tenofovir disoproxil fumarate, Pegasys, peginterferon alfa-2a, Nucleos(t)ide
Assembly Biosciences
Chronic Hepatitis B
03/18
06/18
NCT02401737: Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients

Completed
1b
58
US, RoW
NVR 3-778, Placebo for NVR 3-778, Pegasys, peginterferon alfa-2a
Novira Therapeutics, Inc.
Chronic Hepatitis B
05/16
05/16
NCT01087944: A Study of Administration of Peginterferon Alfa-2a [Pegasys] by Autoinjector Versus Pre-filled Syringe in Patients With Chronic Hepatitis C

Completed
1
60
US
Autoinjector, Pre-filled syringe
Hoffmann-La Roche
Hepatitis C, Chronic
06/10
06/10
NCT00882193: Pilot Study of Betaine + Combination Antiviral Therapy for Chronic Hepatitis C Genotype 1 Non-responder/Relapsers

Terminated
1
2
US
Betaine, trimethylglycine, Peginterferon alpha 2a, Pegasys, Ribavirin, Copegus
University of Nebraska
Chronic Hepatitis C, Genotype 1, Relapse
01/11
01/11
NCT01889849: Comparative Pharmacokinetics and Pharmacodynamics of Peginterferon BIP48 and 40kDa in Healthy Volunteers

Completed
1
32
RoW
BIP 48, Peginterferon alfa 2b 48kDA, Pegasys, Peginterferon alfa 2a 40kDA
The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz)
Chronic Viral Hepatitis C
08/11
08/11
NCT01185860: A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1

Completed
1
59
Europe, RoW
danoprevir, peginterferon alfa-2a [Pegasys], placebo, ribavirin, ritonavir
Hoffmann-La Roche
Hepatitis C, Chronic
01/12
01/12
NCT00962871: A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both

Completed
1
30
US, RoW
peginterferon alfa-2a [Pegasys], tenofovir
Hoffmann-La Roche
Hepatitis B, Chronic
02/12
02/12
NCT01337375: A Study of the Pharmacokinetics And Pharmacodynamics of Intravenously Administered Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C And Previous Non-Response to Pegylated Interferon And Ribavirin Combination Therapy

Completed
1
31
Europe
peginterferon alfa 2a [Pegasys], peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis C, Chronic
04/12
04/12
NCT00962975: A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies

Completed
1
29
US, RoW
peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
05/13
05/13
NCT02112799: Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patients

Completed
1
55
RoW
NVR 3-778, Placebo for NVR 3-778, Pegasys, peginterferon alfa-2a
Novira Therapeutics, Inc.
Chronic Hepatitis B
05/16
05/16

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