Hepatitis B  >>  Pegasys (pegylated interferon α -2a)  >>  Phase 4
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22 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Pegasys (pegylated interferon α -2a) / Roche
NCT02604823: A Study of Peginterferon Alfa-2a (Pegasys) in Participants With Hepatitis B E-Antigen (HBeAg)-Positive Chronic Hepatitis B Virus (HBV)

Completed
4
307
RoW
Peginterferon alfa-2a, Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
11/05
11/05
NCT02570191: A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV)

Completed
4
60
Europe
Peginterferon alfa-2a, Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
02/07
02/07
NCT00226382: Treatment With Peginterferon Alfa-2a (40 KD) of Chronic Hepatitis B Patients, Who Have Failed Anti-viral Treatment

Completed
4
50
RoW
Pegylated Interferon-alfa-2a
Chinese University of Hong Kong, Hoffmann-La Roche
Chronic Hepatitis B
04/08
04/08
NCT01519921: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Positive Chronic Hepatitis B.

Completed
4
150
RoW
peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
06/08
06/08
NCT02791269: A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access Program

Completed
4
24
RoW
Peginterferon alfa-2a, Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
07/08
07/08
NCT00291616: Efficacy Study of Thymosin alpha1 & Pegylated Interferon-alpha2a to Treat Chronic Hepatitis B

Completed
4
52
RoW
Pegylated Interferon-alpha2a, Thymosin alpha1 & Pegylated Interferon-alpha2a
Seoul National University Hospital, Roche Pharma AG, SciClone Pharmaceuticals
Chronic Hepatitis B
08/08
08/08
NCT02598063: A Study to Evaluate Efficacy and Safety of Peginterferon Alfa-2a (Pegasys) and Adeforvir Dipivoxil (ADV) in Participants With Lamivudine-Resistant Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis B

Completed
4
255
RoW
Adefovir dipivoxil, Lamivudine, Peginterferon alfa-2a, Pegasys
Hoffmann-La Roche
Hepatitis B, Chronic
04/09
04/09
NCT01787279: An Expanded Access Study of Pegasys (Peginterferon Alfa-2a) in Patients With HBeAg-Negative Chronic Hepatitis B

Completed
4
59
RoW
Peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
05/09
05/09
NCT00487747: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis B.

Completed
4
18
RoW
peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
10/09
10/09
NCT00614471: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Entecavir in Treatment-Naive Patients With HBeAg-Positive Chronic Hepatitis B.

Completed
4
219
RoW
Entecavir, peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
10/09
10/09
NCT00436163 / 2006-005370-49: A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B

Completed
4
39
Europe
Peginterferon alfa-2a, Pegasys®
Hoffmann-La Roche
Hepatitis B, Chronic
05/10
05/10
NCT00435825 / 2006-000870-63: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).

Completed
4
551
US, Europe, RoW
peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
12/10
12/10
NCT00940485: A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis B

Completed
4
200
RoW
entecavir, peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
12/11
12/11
NCT01086085: A Study of Peginterferon Alfa-2a [PEGASYS] in Patients With Chronic Hepatitis B Who Are HBeAg Positive

Completed
4
265
RoW
Adefovir, peginterferon alfa-2a [PEGASYS]
Hoffmann-La Roche, Major Science and Technology Special Project of China Eleventh Five-year
Hepatitis B, Chronic
03/13
03/13
ARES, NCT00877760 / 2008-006239-11: Augmenting Response to Entecavir With Peginterferon a-2a for the Treatment of HBeAg-positive Chronic Hepatitis B

Completed
4
184
Europe, RoW
pegylated interferon a-2a, Pegasys, Entecavir, Baraclude
Foundation for Liver Research
Chronic Hepatitis B
07/13
07/13
NCT01277601 / 2010-024586-45: Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis B

Completed
4
751
US, Canada, Europe, RoW
TDF, Viread®, Peg-IFN, Pegasys®
Gilead Sciences
Chronic Hepatitis B
08/14
07/15
NCT00922207: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis B

Completed
4
280
RoW
Adefovir, Entecavir, Placebo, peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
09/14
09/14
NCT00927082: A Follow-Up Study to WV19432, to Evaluate Long Term Post-Treatment Effects of PEGASYS (Peginterferon Alfa-2a(40KD))in Patients With HBeAg Positive Chronic Hepatitis B

Completed
4
383
RoW
peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis B, Chronic
11/14
11/14
NCT01179594: A Study of 48 Versus 96 Weeks of Peginterferon Alfa-2a [Pegasys] Treatment, With or Without Entecavir, in Patients With Chronic Hepatitis B.

Withdrawn
4
0
NA
entecavir, peginterferon alfa-2a [Pegasys], placebo
Hoffmann-La Roche
Hepatitis B, Chronic
11/14
11/14
NCT01938781: Optimized Treatment and Regression of HBV-induced Liver Fibrosis

Completed
4
400
RoW
entecavir, entecavir dispersible tablets, Peg-IFN, Pegasys
Beijing Friendship Hospital, Peking University People's Hospital, RenJi Hospital, Peking University, Shanghai Zhongshan Hospital, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Public Health Clinical Center, Nanfang Hospital of Southern Medical University, Sir Run Run Shaw Hospital, Beijing YouAn Hospital, Peking University First Hospital, Beijing 302 Hospital, Peking Union Medical College Hospital, Beijing Ditan Hospital, Beijing Tiantan Hospital, Huashan Hospital, Tongji Hospital, Tang-Du Hospital, Fifth Hospital of Shijiazhuang City, Logistics University of Chinese People's Armed Police Forces, The First Affiliated Hospital of Shanxi Medical University, The Affiliated Hospital of Yanbian University
Liver Fibrosis
12/16
12/16
E+VIP, NCT02097004: Study of Therapeutic Vaccination With Intensified Schedule Plus Pegasys Dual Therapy on Chronic Hepatitis B Infection

Completed
4
111
RoW
Peginterferon alfa-2a, Pegasys, HBV vaccination, Euvax B Inj, Entecavir, Baracrude
Seoul National University Hospital
Hepatitis B, Chronic
01/18
03/18
NCT03084250: The Investigation of Peginterferon Alfa-2a on Optimal in Chronic Hepatitis B Patients Who Have a High Risk of HCC

Active, not recruiting
4
150
RoW
Peginterferon Alfa-2A, Pegasys, Adefovir, entecavir,tenofovir, either of them
Shanghai Nanhui Nanhua Hospital
Hepatitis B
04/23
12/23

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