Pegasys (pegylated interferon α -2a) / Roche |
NCT02908191: A Study in Healthy Volunteers and Patients With Chronic Hepatitis B |
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| Completed | 1a/1b | 86 | RoW | ABI-H0731, Placebo for ABI-H0731, Sugar pill manufactured to mimic the ABI-H0731 tablet, Entecavir, Tenofovir disoproxil fumarate, Pegasys, peginterferon alfa-2a, Nucleos(t)ide | Assembly Biosciences | Chronic Hepatitis B | 03/18 | 06/18 | | |
NCT02401737: Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients |
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| Completed | 1b | 58 | US, RoW | NVR 3-778, Placebo for NVR 3-778, Pegasys, peginterferon alfa-2a | Novira Therapeutics, Inc. | Chronic Hepatitis B | 05/16 | 05/16 | | |
NCT01087944: A Study of Administration of Peginterferon Alfa-2a [Pegasys] by Autoinjector Versus Pre-filled Syringe in Patients With Chronic Hepatitis C |
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| Completed | 1 | 60 | US | Autoinjector, Pre-filled syringe | Hoffmann-La Roche | Hepatitis C, Chronic | 06/10 | 06/10 | | |
NCT00882193: Pilot Study of Betaine + Combination Antiviral Therapy for Chronic Hepatitis C Genotype 1 Non-responder/Relapsers |
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| Terminated | 1 | 2 | US | Betaine, trimethylglycine, Peginterferon alpha 2a, Pegasys, Ribavirin, Copegus | University of Nebraska | Chronic Hepatitis C, Genotype 1, Relapse | 01/11 | 01/11 | | |
NCT01889849: Comparative Pharmacokinetics and Pharmacodynamics of Peginterferon BIP48 and 40kDa in Healthy Volunteers |
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| Completed | 1 | 32 | RoW | BIP 48, Peginterferon alfa 2b 48kDA, Pegasys, Peginterferon alfa 2a 40kDA | The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) | Chronic Viral Hepatitis C | 08/11 | 08/11 | | |
NCT01185860: A Study of Ritonavir-Boosted Danoprevir (RO5190591) in Combination With Pegasys and Ribavirin in Patients With Chronic Hepatitis C Genotype 1 |
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| Completed | 1 | 59 | Europe, RoW | danoprevir, peginterferon alfa-2a [Pegasys], placebo, ribavirin, ritonavir | Hoffmann-La Roche | Hepatitis C, Chronic | 01/12 | 01/12 | | |
NCT00962871: A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both |
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| Completed | 1 | 30 | US, RoW | peginterferon alfa-2a [Pegasys], tenofovir | Hoffmann-La Roche | Hepatitis B, Chronic | 02/12 | 02/12 | | |
NCT01337375: A Study of the Pharmacokinetics And Pharmacodynamics of Intravenously Administered Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C And Previous Non-Response to Pegylated Interferon And Ribavirin Combination Therapy |
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| Completed | 1 | 31 | Europe | peginterferon alfa 2a [Pegasys], peginterferon alfa-2a [Pegasys] | Hoffmann-La Roche | Hepatitis C, Chronic | 04/12 | 04/12 | | |
NCT00962975: A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies |
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| Completed | 1 | 29 | US, RoW | peginterferon alfa-2a [Pegasys] | Hoffmann-La Roche | Hepatitis B, Chronic | 05/13 | 05/13 | | |
NCT02112799: Safety and Efficacy Study of NVR 3-778 in Healthy Volunteers and Hepatitis B Patients |
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| Completed | 1 | 55 | RoW | NVR 3-778, Placebo for NVR 3-778, Pegasys, peginterferon alfa-2a | Novira Therapeutics, Inc. | Chronic Hepatitis B | 05/16 | 05/16 | | |