Skin Diseases  >>  sorafenib  >>  Phase 2
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15 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
sorafenib / Generic mfg.
NCT00493636: 1st or 2nd Line MBC (Metastatic Breast Cancer) With Previous Avastin (Bevacizumab) Therapy

Checkmark +gem/cape in pts who progressed during or after bevacizumab
Feb 2013 - Feb 2013: +gem/cape in pts who progressed during or after bevacizumab
Checkmark P2 data (TIES)
Mar 2012 - Mar 2012: P2 data (TIES)
Checkmark P2 data
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Completed
2b
160
US
Gemcitabine, Gemzar, Sorafenib, Nexavar, Placebo, Sugar pill, Capecitabine, Xeloda
Accelerated Community Oncology Research Network, Amgen
Breast Cancer
09/10
11/12
NCT00101400: BAY43-9006 - Phase II in Advanced Breast Cancer

Completed
2
54
Europe
Sorafenib (Nexavar, BAY43-9006)
Bayer
Breast Neoplasms, Breast Cancer
01/06
01/08
NCT00096434: Sorafenib in Treating Patients With Metastatic Breast Cancer

Completed
2
23
US
sorafenib tosylate, laboratory biomarker analysis
National Cancer Institute (NCI)
Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer
06/06
 
NCT00632541: A Phase II Study of Bevacizumab + Sorafenib in Metastatic Breast Cancer

Checkmark In combination with sorafenib in pts with mBC
Jul 2013 - Jul 2013: In combination with sorafenib in pts with mBC
Terminated
2
18
US
Sorafenib, Bevacizumab, Imaging
Hoosier Cancer Research Network, Genentech, Inc., Bayer, Amgen
Metastatic Breast Cancer
03/09
03/09
NCT00607438: A Phase II Study Of Abraxane and Nexavar in the First-Line Treatment of Locally Advanced or Metastatic Breast Cancer

Terminated
2
16
US
Paclitaxel Albumin Nanoparticle for Injectable Suspension (Abraxane), Abraxane, Sorafenib (Nexavar), Nexavar
Veeda Oncology, Bayer, Celgene Corporation
Breast Cancer
05/09
05/09
NCT00722072: Sorafenib and Fulvestrant in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Aromatase Inhibitor Therapy

Terminated
2
12
US
fulvestrant, sorafenib tosylate
OHSU Knight Cancer Institute, National Cancer Institute (NCI)
Breast Cancer
07/10
07/12
SOFIA, NCT00548899 / 2007-000124-41: Neoadjuvant Chemotherapy Including Sorafenib in Women With Previously Untreated Primary Breast Cancer

Completed
2
36
Europe
Nexavar (Sorafenib)
German Breast Group, Bayer
Breast Cancer
09/11
12/11
NCT00525161: Study Adding Multikinase Inhibitor Sorafenib to Existing Endocrine Therapy in Patients With Advanced Breast Cancer

Terminated
2
11
US
sorafenib, Nexavar
Suleiman Massarweh, Bayer
Breast Cancer
01/13
01/15
NCT00573755: Sorafenib and Letrozole, Anastrozole, or Exemestane in Treating Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Metastatic Breast Cancer

Checkmark Data-SABCS
Dec 2011 - Dec 2011: Data-SABCS
Terminated
2
4
US
anastrozole, exemestane, letrozole, sorafenib tosylate, placebo
Mayo Clinic, National Cancer Institute (NCI)
Breast Cancer
04/13
04/13
NCT01320111 / 2009-018025-73: Breast Cancer Study: Paclitaxel Versus Paclitaxel Plus Sorafenib in Second- or Third-line Treatment

Completed
2
59
Europe
Paclitaxel and Sorafenib, sorafenib = nexavar, Paclitaxel
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH, iOMEDICO AG
Metastatic Breast Cancer
08/14
08/14
NCT01194869: Preoperative Trial of Sorafenib in Combination With Cisplatin Followed by Paclitaxel for Early Stage Breast Cancer

Terminated
2
25
US
Sorafenib, Nexavar, Cisplatin, Platinol, CDDP, Cis-diamminedichloroplatinum(II), Paclitaxel, Taxol
Emory University, Amgen, Bayer
Breast Cancer
06/15
06/15
NCT01762150: Sorafenib Combined With Chemotherapy for Renal Collecting Duct Carcinoma

Checkmark ASCO 2014
May 2014 - May 2014: ASCO 2014
Completed
2
26
RoW
Sorafenib, Nexavar, Gemcitabine, Gemzar, Cisplatin, Cis-Dichlorodiamineplatinum
Peking University Cancer Hospital & Institute, Bayer
Renal Cell Carcinoma
12/16
06/18
NCT00217399: Sorafenib and Anastrozole in Treating Postmenopausal Women With Metastatic Breast Cancer

Completed
1/2
35
US
sorafenib tosylate, BAY 43-9006, BAY 43-9006 Tosylate Salt, BAY 54-9085, Nexavar, SFN, anastrozole, ANAS, Arimidex, ICI-D1033
National Cancer Institute (NCI)
Recurrent Breast Cancer, Stage IV Breast Cancer
07/09
01/13
NCT00825734: Phase I/II Trial of Sorafenib Plus Ixabepilone in HER2-Negative Metastatic Breast Cancer

Checkmark P2 data - SABCS
Dec 2012 - Dec 2012: P2 data - SABCS
Completed
1/2
83
US
Sorafenib, Nexavar (Sorafenib), Ixabepilone, Ixempra (Ixabepilone)
SCRI Development Innovations, LLC, Bayer, Bristol-Myers Squibb
Metastatic Breast Cancer
06/13
08/14
NCT00828074: Sorafenib and Vinorelbine in Treating Women With Stage IV Breast Cancer

Checkmark Vinorelbine & sorafenib in mBC
Dec 2013 - Dec 2013: Vinorelbine & sorafenib in mBC
Completed
1/2
46
US
sorafenib tosylate, vinorelbine ditartrate
City of Hope Medical Center, National Cancer Institute (NCI)
Breast Cancer
04/14
04/14

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