Sarcoma  >>  Neupogen (filgrastim)  >>  Phase 2
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46 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Neupogen (filgrastim) / Kyowa Kirin, Amgen
SAKK 57/93, NCT00002526: Chemotherapy in Treating Patients With Advanced Sarcoma

Completed
2
20
Europe
filgrastim, doxorubicin hydrochloride, ifosfamide
Swiss Group for Clinical Cancer Research
Ovarian Cancer, Sarcoma
09/95
09/95
NCT00001059: Comparison of Liposomal Doxorubicin Used Alone or in Combination With Bleomycin Plus Vincristine in the Treatment of Kaposi's Sarcoma in Patients With AIDS

Completed
2
120
US
Doxorubicin hydrochloride (liposomal), Filgrastim, Bleomycin sulfate, Vincristine sulfate
National Institute of Allergy and Infectious Diseases (NIAID), Sequus Pharmaceuticals, Amgen
Sarcoma, Kaposi, HIV Infections
 
08/98
NCT00003776: Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Completed
2
US
filgrastim, cisplatin, doxorubicin hydrochloride, ifosfamide, leucovorin calcium, methotrexate, trimetrexate glucuronate, surgical procedure
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Sarcoma
03/00
03/00
NCT00002804: Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

Completed
2
43
US, Europe
filgrastim, Granulocyte-Colony Stimulating Factor, Neupogen, G-CSF, doxorubicin hydrochloride, Adriamycin, NSC#123127, ifosfamide, Isophosphamide, IFEX, mesna, Sodium 2-Mercaptoethane Sulfonate, Mesnex, Urimetexan, NSC#113891, vincristine sulfate, VCR, Oncovin, NSC#67574, conventional surgery, brachytherapy, low-LET cobalt-60 gamma ray therapy, low-LET electron therapy, low-LET photon therapy
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
06/00
04/06
NCT00003657: High-dose ICE With Amifostine

Completed
2
24
US
filgrastim, Amifostine, Ethyol®, Carboplatin, Paraplatin, Etoposide, Toposar, VePesid, Etopophos, Ifosfamide, Ifex, peripheral blood stem cell transplantation
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Bladder Cancer, Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Extragonadal Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer, Lung Cancer, Ovarian Cancer, Sarcoma, Testicular Germ Cell Tumor, Unspecified Adult Solid Tumor, Protocol Specific
11/00
06/02
NCT00004157: Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors

Completed
2
US
filgrastim, recombinant interleukin-11
Fred Hutchinson Cancer Center, National Cancer Institute (NCI)
Breast Cancer, Gestational Trophoblastic Tumor, Kidney Cancer, Lymphoma, Neuroblastoma, Ovarian Cancer, Sarcoma, Testicular Germ Cell Tumor
04/02
04/02
NCT00002791: Chemotherapy Plus Radiation Therapy Followed by Surgery in Treating Patients With Soft Tissue Sarcoma

Completed
2
US, Canada, RoW
filgrastim, dacarbazine, doxorubicin hydrochloride, ifosfamide, mesna, conventional surgery, brachytherapy, intraoperative radiation therapy, radioisotope therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI), Eastern Cooperative Oncology Group
Sarcoma
05/02
11/13
NCT00002643: Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Ewing's Sarcoma or Primitive Neuroectodermal Tumor

Completed
2
130
US, Canada, Europe, RoW
filgrastim, amifostine trihydrate, cyclophosphamide, doxorubicin hydrochloride, etoposide, ifosfamide, topotecan hydrochloride, vincristine sulfate, conventional surgery, low-LET cobalt-60 gamma ray therapy, low-LET electron therapy, low-LET photon therapy
National Cancer Institute (NCI), Children's Cancer Group
Neutropenia, Sarcoma
06/03
 
NCT00004066: Gemcitabine, Docetaxel, and Filgrastim in Treating Patients With Recurrent or Persistent Leiomyosarcoma or Soft Tissue Sarcoma

Completed
2
82
US
filgrastim, docetaxel, gemcitabine hydrochloride
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Ovarian Cancer, Sarcoma, Small Intestine Cancer
10/03
10/03
NCT00002825: Docetaxel in Treating Children With Recurrent Solid Tumors

Completed
2
20
US, Canada, RoW
filgrastim, docetaxel
National Cancer Institute (NCI)
Brain and Central Nervous System Tumors, Neuroblastoma, Sarcoma
12/04
 
NCT00003955: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Completed
2
77
Europe, Canada, US, RoW
dactinomycin, filgrastim, pegfilgrastim, sargramostim, cyclophosphamide, irinotecan hydrochloride, vincristine sulfate, radiation therapy
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
01/05
10/09
NCT00002515: Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancer

Completed
2
US
filgrastim, carboplatin, thiotepa, topotecan hydrochloride, autologous bone marrow transplantation, bone marrow ablation with stem cell support, in vitro-treated bone marrow transplantation
Memorial Sloan Kettering Cancer Center
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer, Liver Cancer, Lymphoma, Neuroblastoma, Ovarian Cancer, Retinoblastoma, Sarcoma, Testicular Germ Cell Tumor
04/05
04/05
NCT00023998: Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Completed
2
80
US
doxorubicin hydrochloride, ADM, ADR, Adria, Adriamycin PFS, Adriamycin RDF, cisplatin, CACP, CDDP, CPDD, DDP, methotrexate, amethopterin, Folex, methylaminopterin, Mexate, MTX, leucovorin calcium, CF, CFR, LV, filgrastim, G-CSF, Neupogen, therapeutic conventional surgery, radiation therapy, irradiation, radiotherapy, therapy, radiation, etoposide, EPEG, VP-16, VP-16-213, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, trastuzumab, anti-c-erB-2, Herceptin, MOAB HER2, laboratory biomarker analysis
National Cancer Institute (NCI)
Metastatic Osteosarcoma
11/05
05/07
NCT00101127: Docetaxel, Gemcitabine, and Filgrastim (G-CSF) or Pegfilgrastim in Treating Patients With Advanced, Persistent, or Recurrent Uterine Leiomyosarcoma

Completed
2
US
filgrastim, pegfilgrastim, docetaxel, gemcitabine hydrochloride
Gynecologic Oncology Group, National Cancer Institute (NCI)
Sarcoma
07/06
 
NCT00019864: Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Terminated
2
100
US
filgrastim, cisplatin, dexrazoxane hydrochloride, doxorubicin hydrochloride, leucovorin calcium, methotrexate, adjuvant therapy, conventional surgery, neoadjuvant therapy
National Cancer Institute (NCI)
Cardiac Toxicity, Sarcoma
12/06
10/11
NCT00035620: Pegfilgrastim as Support to Pediatric Sarcoma Patients Receiving Chemotherapy

Completed
2
44
US
pegfilgrastim, filgrastim
Amgen
Sarcoma, Neutropenia
01/07
04/07
NCT00031629: Combination Chemotherapy and Filgrastim or Pegfilgrastim in Treating Patients With Recurrent or Persistent Cancer of the Uterus

Completed
2
51
US
Docetaxel, Docecad, RP56976, Taxotere, Taxotere Injection Concentrate, Filgrastim, Filgrastim XM02, Filgrastim-sndz, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tbo-filgrastim, Tevagrastim, Zarxio, Gemcitabine Hydrochloride, dFdCyd, Difluorodeoxycytidine Hydrochloride, Gemzar, LY-188011, LY188011, Pegfilgrastim, Filgrastim SD-01, filgrastim-SD/01, HSP-130, Neulasta, Neulastim, Pegfilgrastim Biosimilar HSP-130, SD-01, SD-01 sustained duration G-CSF
Gynecologic Oncology Group, National Cancer Institute (NCI)
Recurrent Uterine Corpus Sarcoma, Uterine Corpus Leiomyosarcoma
07/07
 
NCT00025363: Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

Completed
2
150
US
vincristine sulfate, leurocristine sulfate, VCR, Vincasar PFS, irinotecan hydrochloride, Campto, Camptosar, CPT-11, irinotecan, U-101440E, cyclophosphamide, CPM, CTX, Cytoxan, Endoxan, Endoxana, doxorubicin hydrochloride, ADM, ADR, Adria, Adriamycin PFS, Adriamycin RDF, ifosfamide, Cyfos, Holoxan, IFF, IFX, IPP, etoposide, EPEG, VP-16, VP-16-213, tirapazamine, SR 4233, Tirazone, WIN 59075, filgrastim, G-CSF, Neupogen, sargramostim, GM-CSF, Leukine, Prokine, pharmacological study, pharmacological studies, pharmacogenomic studies, Pharmacogenomic Study, laboratory biomarker analysis
National Cancer Institute (NCI)
Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma, Embryonal-botryoid Childhood Rhabdomyosarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Childhood Rhabdomyosarcoma
10/07
 
NCT00084838: Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT

Completed
2
25
US
filgrastim, filgrastim XM02, G-CSF, cisplatin, CACP, cis-DDP, cis-diamminedichloro platinum (II), cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cismaplat, Platinol, cyclophosphamide, Ciclofosfamida, Ciclofosfamide, Claphene, CP monohydrate, CPM, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphanum, Cytophosphane, Mitoxan, Syklofosfamid, Zytoxan, Clafen, Cytoxan, Neosar, cytarabine, arabinofuranosylcytosine, arabinosylcytosine, aracytidine, beta-cytosine arabinoside, cytarabine hydrochloride, cytarabinum, cytosine arabinoside, cytosine arabinosine hydrochloride, Cytosar-U, Tarabine PFS, dexrazoxane hydrochloride, Totect, Zinecard, doxorubicin hydrochloride, Adriamycin PFS, Adriamycin RDF, etoposide, VP-16, leucovorin calcium, folinate calcium, folinic acid, methotrexate, temozolomide, Temodar, Methazolastone, Temodal, TMZ, CCRG-81045, therapeutic hydrocortisone, vincristine sulfate, leurocristine sulfate, Vincasar PFS, radiation therapy, Dactinomycin, ACT-D, actinomycin C1, actinomycin D, actinomycin I1, actinomycin IV, actinomycin X 1, actinomycin-[thr-val-pro-sar-meval], AD, dactinomycine, meractinomycin
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Central Nervous System Tumor, Pediatric
02/08
03/13
NCT00072280: Surgery and/or Chemotherapy in Treating Children With Infantile, Congenital, or Childhood Fibrosarcoma

Terminated
2
7
US, Canada, RoW
dactinomycin, DACT, Actinomycin-D, Cosmegen, NSC #3053, cyclophosphamide, Cytoxan, NSC #26271, etoposide, ETOP, VePesid, Etopophos, VP-16, NSC #141540, ifosfamide, Isophosphamide, Iphosphamide, Z4942, Ifex, NSC #109724, vincristine sulfate, Oncovin, VCR, LCR, NSC #67574, Conventional Surgery, MESNA (mercaptoethane sulfonate), Sodium 2-mercaptoethane sulfonate, UCB 3983, Mesnex, NSC #113891, Filgrastim, Granulocyte Colony-Stimulating Factor, r-metHuG-CSF, G-CSF, Neupogen, NSC #614629
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
03/08
03/08
NCT00061893: Vinblastine, Celecoxib, and Combination Chemotherapy in Treating Patients With Newly-Diagnosed Metastatic Ewing's Sarcoma Family of Tumors

Completed
2
38
Canada, US, RoW
celecoxib, cyclophosphamide, doxorubicin hydrochloride, etoposide, ifosfamide, vinblastine sulfate, vincristine sulfate, conventional surgery, radiation therapy, MESNA, Filgrastim, G-CSF
Children's Oncology Group, National Cancer Institute (NCI)
Sarcoma
04/08
12/13
NCT00245011: Samarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma

Completed
2
11
US
filgrastim, Neupogen, ifosfamide, Ifex, peripheral blood stem cell transplantation, Sm-EDTMP (low dose), sm-EDTMP (higher dose)
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, National Cancer Institute (NCI)
Sarcoma
10/08
03/09
NCT00043979: Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas

Completed
2
60
US
F-18 Fluorodeoxyglucose, FDG, therapeutic allogeneic lymphocytes, cyclophosphamide, Cytoxan, cyclosporine, Sandimmune, doxorubicin hydrochloride, Adriamycin, etoposide, Vepesid, fludarabine phosphate, Fludara, melphalan, Alkeran, prednisone, Deltasone, sirolimus, Rapamune, tacrolimus, Prograf, vincristine sulfate, Oncovin, peripheral blood stem cell transplantation, PBSCT, Filgrastim, Peripheral Blood Stem Cell donation
National Cancer Institute (NCI)
Sarcoma
05/09
12/11
NCT00068393: Doxorubicin and Gemcitabine in Treating Patients With Locally Recurrent or Metastatic Unresectable Renal Cell Carcinoma

Completed
2
39
US
Doxorubicin, Adriamycin, Rubex, Gemcitabine, G-CSF (granulocyte-colony stimulating factor), Neupogen, Filgrastim, Neulasta, pegfilgrastim
Eastern Cooperative Oncology Group, National Cancer Institute (NCI)
Metastatic Renal Cell Carcinoma, Renal Cell Carcinoma With Sarcomatoid Features
06/09
05/11
NCT00073983: Gemcitabine and Docetaxel in Treating Patients With Recurrent Osteosarcoma (Closed to Accrual as of 12/21/06) or Ewing's Sarcoma or Unresectable or Locally Recurrent Chondrosarcoma

Completed
2
54
US
filgrastim, pegfilgrastim, docetaxel, gemcitabine hydrochloride, microarray analysis, laboratory biomarker analysis, pharmacokinetic study
Sarcoma Alliance for Research through Collaboration
Sarcoma
01/10
12/10
NCT00025441: Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Completed
2
Europe
dactinomycin, filgrastim, carboplatin, cyclophosphamide, doxorubicin hydrochloride, epirubicin hydrochloride, etoposide, ifosfamide, vincristine sulfate, peripheral blood stem cell transplantation, radiation therapy
Societe Internationale d'Oncologie Pediatrique, Children's Cancer and Leukaemia Group, Societe Francaise Oncologie Pediatrique
Ovarian Cancer, Sarcoma, Small Intestine Cancer
 
03/10
NCT00089544: Preoperative Thalidomide With Radiation Therapy For Patients With Low-Grade Primary Soft Tissue Sarcoma or Thalidomide With Radiation Therapy and Chemotherapy For Patients With High-Grade or Intermediate-Grade Primary Soft Tissue Sarcoma of the Arm, Leg, or Body Wall

Terminated
2
23
US
Dacarbazine, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, Asercit, Biocarbazine, Dacarbazina, Dacarbazina Almirall, Dacarbazine - DTIC, Dacatic, Dakarbazin, Deticene, Detimedac, DIC, Dimethyl (triazeno) imidazolecarboxamide, Dimethyl Triazeno Imidazol Carboxamide, Dimethyl Triazeno Imidazole Carboxamide, dimethyl-triazeno-imidazole carboxamide, Dimethyl-triazeno-imidazole-carboximide, DTIC, DTIC-Dome, Fauldetic, Imidazole Carboxamide, Imidazole Carboxamide Dimethyltriazeno, WR-139007, Doxorubicin Hydrochloride, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), ADM, Adriacin, Adriamycin, Adriamycin Hydrochloride, Adriamycin PFS, Adriamycin RDF, ADRIAMYCIN, HYDROCHLORIDE, Adriamycine, Adriblastina, Adriblastine, Adrimedac, Chloridrato de Doxorrubicina, DOX, DOXO-CELL, Doxolem, Doxorubicin.HCl, Doxorubin, Farmiblastina, FI 106, FI-106, hydroxydaunorubicin, Rubex, Filgrastim, FILGRASTIM, LICENSE HOLDER UNSPECIFIED, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tevagrastim, Ifosfamide, Asta Z 4942, Asta Z-4942, Cyfos, Holoxan, Holoxane, Ifex, IFO, IFO-Cell, Ifolem, Ifomida, Ifomide, Ifosfamidum, Ifoxan, IFX, Iphosphamid, Iphosphamide, Iso-Endoxan, Isoendoxan, Isophosphamide, Mitoxana, MJF 9325, MJF-9325, Naxamide, Seromida, Tronoxal, Z 4942, Z-4942, Laboratory Biomarker Analysis, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, irradiation, RADIATION, Radiotherapeutics, radiotherapy, RT, Therapy, Radiation, Thalidomide, (+)-Thalidomide, (-)-Thalidomide, .alpha.-Phthalimidoglutarimide, 2, 6-Dioxo-3-phthalimidopiperidine, Alpha-Phthalimidoglutarimide, Contergan, Distaval, Kevadon, N-(2,6-Dioxo-3-piperidyl)phthalimide, N-Phthaloylglutamimide, N-Phthalylglutamic Acid Imide, Neurosedyn, Pantosediv, Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (+)-, Phthalimide, N-(2, 6-dioxo-3-piperidyl)-, (-)-, Sedalis, Sedoval K-17, Softenon, Synovir, Talimol, Thalomid, Therapeutic Conventional Surgery
National Cancer Institute (NCI), Radiation Therapy Oncology Group
Recurrent Adult Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma AJCC v7, Stage II Adult Soft Tissue Sarcoma AJCC v7, Stage III Adult Soft Tissue Sarcoma AJCC v7
09/11
11/13
NCT00544778: Combination Chemotherapy and Dexrazoxane Followed by Surgery and Radiation Therapy in Treating Patients With Advanced Soft Tissue Sarcoma or Recurrent Bone Sarcoma

Terminated
2
7
US
filgrastim, dexrazoxane hydrochloride, doxorubicin hydrochloride, ifosfamide, irinotecan hydrochloride, protein expression analysis, immunoenzyme technique, adjuvant therapy, conventional surgery, neoadjuvant therapy, radiation therapy
City of Hope Medical Center, National Cancer Institute (NCI)
Sarcoma
11/11
 
NCT00189137: Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma

Completed
2
84
US
ifosfamide and doxorubicin vs gemcitabine and docetaxel
University of Michigan Rogel Cancer Center
Sarcoma, Soft Tissue
11/12
10/15
NCT00017160: Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Primary or Recurrent Sarcoma

Withdrawn
2
0
US, Canada
doxorubicin, filgrastim, ifosfamide, biological response modifier therapy, brachytherapy, chemotherapy, colony-stimulating factor therapy, conventional surgery, cytokine therapy, intraoperative radiotherapy, radiation therapy, surgery
Radiation Therapy Oncology Group, National Cancer Institute (NCI)
Stage III Adult Soft Tissue Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Stage IVA Adult Soft Tissue Sarcoma, Stage IIB Adult Soft Tissue Sarcoma, Stage IIC Adult Soft Tissue Sarcoma
 
 
NCT00304083: Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

Completed
2
48
US
filgrastim, doxorubicin hydrochloride, etoposide, ifosfamide, conventional surgery, radiation therapy
Sarcoma Alliance for Research through Collaboration, National Cancer Institute (NCI)
Neurofibromatosis Type 1, Sarcoma
06/14
06/14
NCT00002601: Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma

Completed
2
13
US
filgrastim, cisplatin, doxorubicin hydrochloride, ifosfamide, melphalan, peripheral blood stem cell transplantation
City of Hope Medical Center, National Cancer Institute (NCI)
Sarcoma
09/14
09/14
NCT02259348: Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

Terminated
2
12
US
Cyclophosphamide, Cytoxan, Fludarabine, Fludara, Fludarabine monophosphate, G-CSF, Filgrastim, Neupogen®, Interleukin-2, IL-2, Aldesleukin, Melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran®, Thiotepa, ThioplexV, TESPA, TSPA, Rituximab, Rituxan™, Natural killer cell therapy, NK cell therapy, T-cell depleted HPC transplant, HPC,A Infusion(ɑ/β T cell depleted), CD45RA-depleted HPC transplant
St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myelogenous Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)
04/15
03/16
2015-000087-34: Clinical trial comparing Lipegfilgrastim to Filgrastim in Pediatric Patients Diagnosed with Ewing Family of Tumors or Rhabdomyosarcoma Receiving Chemotherapy. Vizsgálat a lipegfilgrastim kezelés összehasonlítására a filgrastim kezeléssel, Ewing tumorok családjába tartozó betegséggel, vagy rhabdomioszarkómával diagnosztizált és kemoterápiával kezelt gyermek betegekben

Ongoing
2
42
Europe, RoW
Lipegfilgrastim, Neupogen, XM22, Solution for injection, LONQUEX, Neupogen 30 MU (0.3 mg/ml) solution for injection
Merckle GmbH, Merckle GmbH
Neutropenia in pediatric patients diagnosed with Ewing family of Tumors or rhabdomyosarcoma receiving chemotherapy Neutropénia Ewing tumorok családjába tartozó betegséggel, vagy rhabdomioszarkómával diagnosztizált és kemoterápiával kezelt gyermek betegekben, treatment of chemotherapy induced neutropenia (white blood cell decrease) a kemoterápia okozta neutropenia (a fehérvérsejtek csökkenése), Diseases [C] - Blood and lymphatic diseases [C15]
 
 
NCT00003273: Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

Withdrawn
2
0
US, Canada, RoW
filgrastim, carboplatin, cisplatin, cyclophosphamide, etoposide, leucovorin calcium, methotrexate, temozolomide, thiotepa, vincristine sulfate, autologous bone marrow transplantation, peripheral blood stem cell transplantation, radiation therapy
NYU Langone Health
Brain and Central Nervous System Tumors, Neuroblastoma, Retinoblastoma, Sarcoma
 
 
hSTAR GBM, NCT05052957: (Hematopoetic Stem Cell (HPC) Rescue for GBM)

Recruiting
2
16
US
P140K-MGMT, O6-benzylguanine, BG, Photon Based Radiotherapy, temozolomide, TMZ, Filgrastim, G-CSF,Granulocyte-Colony Stimulating Factor, carmustine, BCNU,bis-chloronitrosourea
Leland Metheny, National Cancer Institute (NCI)
Glioblastoma Multiforme, Glioblastoma Multiforme, Adult, Supratentorial Glioblastoma, Supratentorial Gliosarcoma
06/24
12/24
NCT02790515: Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

Recruiting
2
52
US
Anti-thymocyte globulin (rabbit), Thymoglobulin®, rabbit ATG, Blinatumomab, Blincyto, Cyclophosphamide, Cytoxan, Fludarabine, Fludara, G-CSF, Filgrastim, Neupogen®, Melphalan, L-phenylalanine mustard, Phenylalanine mustard, L-PAM, L-sarcolysin, Alkeran, Mesna, Mesnex, Rituximab, Rituxan™, Tacrolimus, FK506, Prograf®, Protopic®, Thiotepa, Thioplex® by Immunex, TESPA, TSPA, HPC,A Infusion, Transplant, CliniMACS, Cell Selection System, Sirolimus, Rapamycin, Rapamune®
St. Jude Children's Research Hospital
Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myeloid Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)
07/24
07/25
NCT00077285: Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma

Active, not recruiting
2
65
US
filgrastim, carboplatin, cyclophosphamide, dexrazoxane hydrochloride, doxorubicin hydrochloride, etoposide, ifosfamide, irinotecan hydrochloride, vincristine sulfate, conventional surgery, radiation therapy
Memorial Sloan Kettering Cancer Center, National Cancer Institute (NCI)
Sarcoma
10/24
10/24
RMS13, NCT01871766: Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

Active, not recruiting
2
98
US
Vincristine, Oncovin®, Dactinomycin, Actinomycin-D, Cosmegen®, Cyclophosphamide, Cytoxan(R), Surgical Resection, Surgery, Radiation, Proton Beam Radiation, External Beam Radiation, Brachytherapy, Bevacizumab, rhuMab, VEGF, Avastin®, Sorafenib, Nexavar®, Myeloid Growth Factor, G-CSF, Filgrastim, Pegfilgrastim, Lymph Node Sampling, Irinotecan, Camptosar ®, Ifosfamide, Ifex ®, Etoposide, VP-16, Vepesid®, Etoposide Phosphate, Etopophos®, Doxorubicin, Adriamycin®, Dexrazoxane, Zinecard, ^1^1C-methionine, Contrast Media
St. Jude Children's Research Hospital
Rhabdomyosarcoma
07/25
06/30
NCT00003425: Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect

Completed
1/2
25
US
filgrastim, amifostine trihydrate, WR-2721, cyclophosphamide, melphalan, peripheral blood stem cell transplantation
University of Kentucky
Breast Cancer, Leukemia, Lymphoma, Neuroblastoma, Ovarian Cancer, Sarcoma, Unspecified Adult Solid Tumor, Protocol Specific
07/02
 
NCT00023738: Chemotherapy, SU5416, Radiation Therapy, and Surgery in Treating Patients With Soft Tissue Sarcoma

Completed
1/2
US, Canada
filgrastim, dacarbazine, doxorubicin hydrochloride, ifosfamide, semaxanib, conventional surgery, radiation therapy
Radiation Therapy Oncology Group, National Cancer Institute (NCI)
Sarcoma
 
10/03
NCT00005952: Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Completed
1/2
30
US
filgrastim, temozolomide, peripheral blood stem cell transplantation
Duke University, National Cancer Institute (NCI)
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer, Neuroblastoma, Ovarian Cancer, Sarcoma, Testicular Germ Cell Tumor
11/05
11/05
NCT00118326: Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease

Completed
1/2
US
filgrastim, allogeneic bone marrow transplantation
Fred Hutchinson Cancer Center
Kidney Cancer, Leukemia, Lymphoma, Myelodysplastic Syndromes, Neuroblastoma, Sarcoma
 
05/07
NCT01027910: PCI-24781 in Combination With Doxorubicin to Treat Sarcoma

Completed
1/2
20
US
PCI-24781, PCI24781, Doxorubicin, Adriamycin, GCSF, Neupogen
Massachusetts General Hospital, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Pharmacyclics LLC.
Sarcoma
03/15
03/15
NCI-2013-00701, NCT00669669: O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomas

Terminated
1/2
12
US
3-Dimensional Conformal Radiation Therapy, 3-dimensional radiation therapy, 3D CONFORMAL RADIATION THERAPY, 3D CRT, 3D-CRT, Conformal Therapy, Radiation Conformal Therapy, Autologous Hematopoietic Stem Cell Transplantation, Autologous Stem Cell Transplantation, Carmustine, BCNU, Becenum, Becenun, BiCNU, Bis(chloroethyl) Nitrosourea, Bis-Chloronitrosourea, Carmubris, Carmustin, Carmustinum, FDA 0345, Gliadel, N,N'-Bis(2-chloroethyl)-N-nitrosourea, Nitrourean, Nitrumon, SK 27702, SRI 1720, WR-139021, Filgrastim, Filgrastim XM02, G-CSF, Neupogen, r-metHuG-CSF, Recombinant Methionyl Human Granulocyte Colony Stimulating Factor, rG-CSF, Tbo-filgrastim, Tevagrastim, In Vitro-Treated Peripheral Blood Stem Cell Transplantation, in vitro-treated PBPC transplantation, in vitro-treated peripheral blood progenitor cell transplantation, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, O6-Benzylguanine, 6-O-BENZYLGUANINE, O(6)-Benzylguanine, Plerixafor, AMD 3100, JM-3100, Mozobil, SDZ SID 791, Proton Beam Radiation Therapy, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac
Fred Hutchinson Cancer Center
Glioblastoma, Gliosarcoma
07/18
01/21
NCT06023641: Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

Recruiting
1/2
100
US
Vincristine, Oncovin, Dactinomycin, (actinomycin-D), Cyclophosphamide, Cytoxan®., Surgical Resection, Proton beam radiation or external beam radiation or brachytherapy, Liposomal irinotecan, (Onivyde®), Vinorelbine, Navelbine, Temozolomide, Temodar, Filgrastim, peg-filgrastim, Neupogen
St. Jude Children's Research Hospital
Rhabdomyosarcoma
10/34
10/37

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