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ACTRN12613000702718: A comparative bioequivalence study of warfarin brands in cardiovascular patients |
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| Not yet recruiting | 4 | 50 | | | Therapeutcs Research Centre, University of South Australia, Therapeutcs Research Centre
university of South Australia | Atrial fibrillation, Venous thrombosis, Pulmonary embolism, Recurrent emboli, Prosthetic valve replacement, Acute myocardial infarction (to prevent systemic embolism) | | | | |
ACTRN12608000446369: Thrombophilia in Pregnancy Prophylaxis Study: a multicentre, multinational, randomised controlled trial of prophylactic low molecular weight heparin in high-risk pregnant thrombophilic women. |
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| Recruiting | 4 | 385 | | | The Ottawa Health Research Institute, Canadian Institute for Health Research | Venous thromboembolism (VTE) and placenta mediated pregnancy complications in thrombophilic women. | | | | |
2012-005410-19: Testing of reversal of anticoagulants in a patient model of controled arterial bleeding |
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| Ongoing | 4 | 30 | Europe | protamine sulfate, -, Solution for infusion, Protamine sulphate | Jessaziekenhuis Hasselt, Jessaziekenhuis Stadsomvaart 11 Hasselt | With the novel oral anticoagulants, including EDOXABAN-DABIGATRANRIVAROXABAN- APIXABAN, we are entering a new era of anticoagulation for atrial fibrillation (AF) (and deep vein thrombosis). Nevertheless, at the time, the lack of a reversal agent is an important limitation with these agents, especially in case of major hemorrhage or the need to perform emergency invasive procedures., Reversal of anticoagulation by drugs, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR-ONC-11001532: Estimation of the warfarin dosage with clinical and pharmacogenetic data for Chinese patients |
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| Completed | 4 | 5000 | | genotype analysis | Institute of Clinical Pharmacology, Central South University; Department of Cardiothoracic Surgery, Xiangya Second Hospital, Central South University, self-funding | Patients who need to take warfarin, including prothetic heart valve replacement, atrial fibrilation, deep vein thrombosis, pulmanory ebolism, stroke. | | | | |
ChiCTR-TRC-11001577: Randomized controlled study of TIPS versus EBL plus propranolol for preventing variceal rebleeding in advanced cirrhotic patients combined with portal vein thrombosis |
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| Completed | 4 | 72 | | TIPS ;EBL+propranolol | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Self-financing | hepatic cirrhosis, esophageal variceal bleeding | | | | |
ChiCTR-TRC-14005223: Efficacy and Safety of rivaroxaban or warfarin on venous thromboembolic disease: A Randomized controlled trial |
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| Recruiting | 4 | 40 | | Warfarin ;rivaroxaban | State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Diseases, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China; First Affiliated Hospital of Guangzhou Medical Uni, self-financing | venous thromboembolic disease | | | | |
2006-006416-30: Effect of two distinct dosing regimen of acetaminophen on the anticoagulant effect of warfarin |
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| Ongoing | 4 | 45 | Europe | Doliprane, Doliprane | Unité de Recherches Thérapeutiques | Arterial and venous thromboembolic disease including atrial fibrillation | | | | |
2006-004199-11: NOSTRADAMUS: Testing for thrombophilia in patients with a first episode of venous thromboembolism: a randomized controlled trial to assess effects on clinical outcomes, quality of life, and costs. |
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| Ongoing | 4 | 1334 | Europe | | Academic Medical Center | A randomized controlled trial of testing and no testing for thrombophilia in patients with a first episode of venous thrombosis or pulmonary embolism (venous thromboembolism, VTE) will be performed. Subsequent additional anticoagulant treatment for a predefined period will be installed in those in whom thrombophilia is detected in the testing group, while others will receive a standard predefined duration of treatment. | | | | |
2007-007890-22: Prevention of portal vein Thrombosis with anticoagulant therapy in patients with hepatic cirrhosis (Child B and C) |
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| Ongoing | 4 | 152 | Europe | CLEXANE*6SIR 4000UI/0,4ML, CLEXANE*6SIR 4000UI/0,4ML | AZIENDA OSPEDALIERA POLICLINICO DI MODENA | Pazienti ambulatoriali e ospedalizzati affetti da cirrosi a eziologia virale o non, in classe B o C di Child, e assenza di trombosi portale o spleno-mesenterica | | | | |
2007-003762-18: Prospective monocenter accuracy study of Vasovist contrast enhanced magnetic resonance venography (CE-MRV) to detect venous thrombi in patients with Ultrasonography detected peripheral acute deep venous thrombosis (DVT) in at least one vessel |
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| Ongoing | 4 | 77 | Europe | VASOVIST, VASOVIST | Hospices Civils de Lyon | Acute deep vein thrombosis (DVT) | | | | |
2010-022119-20: A randomised controlled trial of extended warfarin treatment versus routine warfarin treatment for the prevention of recurrent venous thromboembolism and post thrombotic syndrome in patients being treated for a first episode of unprovoked VTE |
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| Ongoing | 4 | 352 | Europe | Warfarin Sodium, BO1AA, Warfarin sodium, Warfarin sodium | The University of Birmingham | Patients with a Venous Thromboembolism (VTE) | | | | |
2011-002128-41: The influence of renal function on the amount of nadroparin in blood |
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| Ongoing | 4 | 30 | Europe | Fraxiparine, Fraxiparine, Fraxiparine | Erasmus MC, Erasmus MC | Venous thromboembolism | | | | |
ChiCTR-IPR-17012975: Effect of rivaroxaban on venous thromboembolism after posterior lumbar interbody fusion in elderly patients |
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| Completed | 4 | 120 | | Rivaroxaban ;placebo | Guangzhou Panyu Hospital of Chinese Medicine; Guangzhou Panyu Hospital of Chinese Medicine, none | Venous thromboembolism | | | | |
ChiCTR-IPR-15007324: The mechanical and medical prevention of Lower Extremity Deep Venous Thrombosis formation post gynecologic pelvic surgery, a multiple center randomized case control study |
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| Recruiting | 4 | 1000 | | graduated compression stockings ;graduated compression stockings +low molecular weight heparin ;graduated compression stockings + intermittent pneumatic compression ;graduated compression stockings +low molecular weight heparin+intermittent pneumatic compression | Beijing Chaoyang Hospital affiliated to Capital Medical University; Beijing Anzhen Hospital affiliated to Capital Medical University, capital medical development research fund | deep venous thrombosis formation post gynecologic pelvic surgery | | | | |
ChiCTR-IPR-17013008: Randomized open clinical study of indobufen and low molecular weight heparin in preventing the formation of deep vein thrombosis (DVT) after hip arthroplasty |
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| Recruiting | 4 | 200 | | oral Indobufen ;hypodermic injection low-molecular-weight heparin | Hebei Medical University Third Hospital; Hebei Medical University Third Hospital, None | Sterile femoral head necrosis | | | | |
ChiCTR-OPC-17011716: Analysis of the association among rivaroxaban blood concentration, anti-factor Xa activity and clinical prognosis in patients with deep vein thrombosis (DVT) treated with rivaroxaban |
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| Recruiting | 4 | 70 | | rivaroxaban | Peking Union Medical College Hospital; Peking Union Medical College Hospital, self-raised fund | Deep vein thrombosis | | | | |
ChiCTR-IPR-17010898: Effect of anticoagulant treatment on deep vein thrombosis post-endovenous radiofrequency catheter ablation |
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| Recruiting | 4 | 200 | | intravenous injection of 3,000 U of heparin immediately after the sheath puncture, and was followed by an additional 1,000 U of heparin for the subsequent each hour. ;not given heparin injection | The first people’s Hospital of Yunnan Province; The first people，s Hospital of Yunnan Province, Fund support and patient contributions | Venous thrombosis | | | | |
2018-001443-31: DOAC concentrations in blood prior to surgery study: DALI study |
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| Not yet recruiting | 4 | 300 | Europe | Dabigatran, Rivaroxaban, Apixaban, EU/1/08/442/001, EU/1/08/472/025, EU/1/11/691/015, Capsule, hard, Coated tablet, Pradaxa, Xarelto, Eliquis | Leiden University Medical Center, Leiden University Medical Center | No medical condition will be investigated. This study will only investigate DOAC levels during surgery. Patients who use DOACs are patients with venous thrombosis and atrial fibrillation., No medical condition will be investigated. This study will only investigate DOAC levels during surgery. Patients who use DOACs are patients with venous thrombosis and atrial fibrillation., Not possible to specify | | | | |
ChiCTR1800016829: anti-coagulation effect of aspirin, LMWH and rivaroxaban after total hip arthroplasty:a prospective randomised control trial |
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| Recruiting | 4 | 240 | | aspirin ;LMWH ;rivaroxaban | Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University; Department of Orthopaedic Surgery, West China Hospital, West China Medical School, Sichuan University, self-fund | arthroplasty | | | | |
ChiCTR-OPC-17012858: Safety and effectiveness of rivaroxaban in anticoagulation therapy for elderly patients with atrial fibrillation and venous thromboembolism: a prospective observational study |
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| Recruiting | 4 | 200 | | rivaroxaban ;non-rivaroxaban | Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine; Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Self-financing | thrombosis | | | | |
2017-002340-32: APIDULCIS: Extended anticoagulation treatment with low-dose apixaban in patients with a first venous thromboembolism and a positive d-dimer, who were treated with standard course of anticoagulation APIDULCIS: Trattamento a lungo termine con Apixaban a basso dosaggio in pazienti con un primo episodio di tromboembolismo venoso e D-dimero positivo e che sono già stati trattati con terapia anticoagulante |
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| Not yet recruiting | 4 | 1200 | Europe | Apixaban, [BMS-562247-01], Film-coated tablet, ELIQUIS - 2.5 MG-COMPRESSA RIVESTITA CON FILM-USO ORALE-BLISTER (PVC/PVDC/ALU) 60 COMPRESSE | FONDAZIONE ARIANNA ANTICOAGULAZIONE, Bristol-Myers Squibb (BMS) | a first episode of proximal deep vein thrombosis (DVT) and/or pulmonary embolism (PE) Primo episodio di trombosi venosa profonda (TVP) prossimale degli arti inferiori e/o Embolia Polmonare (EP), A first episode of proximal deep vein thrombosis (DVT) with or without a pulmonary embolism (PE) Un primo episodio di trombosi venosa profonda prossimale agli arti inferiori con o senza embolia polmonare associata, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
ChiCTR1800016430: Combined use of rivaroxaban and tranexamic acid for hemorrhage and thrombosis management in spine surgery |
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| Recruiting | 4 | 2000 | | nothing ;Preoperative and intraoperative application of tranexamic acid ;Oral rivaroxaban 8 h after surgery, applied 35 days after surgery ;Preoperative and intraoperative application of tranexamic acid,oral rivaroxaban 8 h after surgery, applied 35 days after surgery | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Self-fund | Venous thromboembolism | | | | |
ChiCTR1800015065: Indobufen in diabetic nephrotic syndrome in patients with deep venous thrombosis prevention and treatment of clinical research |
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| Recruiting | 4 | 176 | | Indobufen tablets ;Clopidogrel | China-Japan Friendship Hospital Clinical Research Ethics Committee; China-Japan Friendship Hospital Clinical Research Ethics Committee, None | Diabetic nephropathy syndrome | | | | |
2018-004450-24: The interaction between the blood thinner edoxaban and the hormonal treatment tamoxifen in breast cancer patients |
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| Not yet recruiting | 4 | 26 | Europe | Lixiana, Film-coated tablet, Lixiana | Tergooi Hospital, dep of internal medicine, Daiichi Sankyo | If there are increased plasma levels of edoxaban when used concomitantly with the P-glycoproteïne inhibitor tamoxifen for the treatment of venous thromboembolism in patients with breast cancer., If the amount of the blood thinner edoxaban in the blood increases while used simoultaneously with the hormonal treatment tamoxifen in patients with breast cancer who have thrombosis, Body processes [G] - Chemical Phenomena [G02] | | | | |
2018-003958-25: Screening for cancer with a very effective imaging technique to early tumors in patients with unprovoked venous thromboembolic disease with a slight risk of developing cancer. Open randomized clinical trial. Detección del cáncer con una técnica de imagen muy eficaz para detectar tumores precozmente en pacientes con enfermedad tromboenbolica venosa no provocada con un algo riesgo de desarrollar cáncer. Ensayo clínico aleatorizado abierto. |
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| Not yet recruiting | 4 | 650 | Europe | Fludesoxiglucosa (18F), Anticoagulant and preservative solution for blood, Fludesoxiglucosa (18F)- IBA | Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla, PI18/01097 (ISCIII) | Venous thromboembolic disease Enfermedad tromboembólica venosa, The purpose of this study is to determine the effectiveness of the use of PET/CT to detect occult cancer in patients with venous thromboembolic disease vs. the diagnostic tests that are commonly used. Se pretende conocer la eficacia del uso de PET/TAC para detectar cáncer oculto en pacientes con enfermedad tromboembólica venosa vs. las pruebas de diagnostico que se utilizan habitualmente., Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02] | | | | |
ChiCTR1800018927: Combined application of rivaroxaban and tranexamic acid in the management of hemorrhage and thrombosis in traumatic surgery |
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| Not yet recruiting | 4 | 1200 | | Physical prophylaxis Lower limb thrombosis ;1g of intravenous tranexamic acid before incision, maintained at 15mg/kg during operation ;1g of tranexamic acid before incision, maintained at 15mg/kg during operation, and rivaroxaban 8 hours after operation | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, Self-fund | Venous thromboembolism | | | | |
ChiCTR1800016711: Clinical study on the improvement of lower extremity deep venous thrombosis and the treatment of constipation by thrombolysis with catheter |
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| Recruiting | 4 | 100 | | Routine nursing + Ear hole sticking pressure + mirabilite coating shenque hole ;Routine nursing | the First Affiliated Hospital of Guangxi Medical University; the First Affiliated Hospital of Guangxi Medical University, Guangxi health and Family Planning Commission | Lower limb deep venous thrombosis | | | | |
ChiCTR1800020289: A randomized controlled trial for Aspirin or Rivaroxaban for venous thromboembolism prophylaxis after total joint arthroplasty |
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| Recruiting | 4 | 120 | | aspirin 100mg bid after operation ;Rivaroxaban 10mg qd after operation | Peking Union Medical College Hospital; Peking Union Medical College Hospital, Orthopaedic department, Peking Union Medical College Hospital | osteoarthritis | | | | |
2014-005162-29: Treatment of thrombosis in the abdominal veins Behandeling van trombose in de buikvenen |
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| Not yet recruiting | 4 | 100 | Europe | rivaroxaban, Tablet, rivaroxaban 20 mg | University of Insubria, Amsterdam UMC, location AMC | Splanchnic vein thrombosis (SVT) is an unusual site manifestation of venous thromboembolism (VTE). It includes the Budd-Chiari syndrome (BCS), portal vein thrombosis (PVT), mesenteric vein thrombosis (MVT) and splenic vein thrombosis (spVT). PVT is the most frequent manifestation of SVT, followed by MVT. Splanchische veneuze trombose (SVT) is wat locatie betreft een ongewoonlijke manifestatie van veneuze trombo-embolie (VTE). Het bevat de Budd-Chiari syndrome, vena porta trombose, vena mesenterica trombose en vena lienalis/splenica trombose., The condition called splanchnic vein thrombosis (SVT) which causes decreased blood flow through one of your splanchnic veins (portal, mesenteric, or splenic vein). d. Bij splanchnische veneuze trombose wordt obstructie veroorzaakt in 1 van de aderen van het maagdarmstelsel, hierdoor kan het zuurstofarme bloed niet meer goed verder kan stromen., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2018-003852-19: An Open Label, Non-Randomised, Phase IV Clinical Trial to Determine the Transfer of Apixaban and Rivaroxaban in Breast Milk Following Oral Administration |
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| Not yet recruiting | 4 | 4 | Europe | Rivaroxaban, Apixaban, Film-coated tablet, Xarelto, Eliquis | King's College London, King's College Hospital NHS Foundation Trust, King's College London, Kings College London | healthy volunteers (Venous Thromboembolism), healthy volunteers (Blood clots during breast feeding), Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
ChiCTR1900024985: Combined use of rivaroxaban and tranexamic acid for hemorrhage and thrombosis management in spine surgery |
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| Not yet recruiting | 4 | 900 | | nothing ;The tranexamic acid 2g was intravenously instilled 30 minutes before the incision, and intraoperative local application of 1 g of tranexamic acid. ;Preoperative and intraoperative application of tranexamic acid,oral rivaroxaban 8 h after surgery, applied 35 days after surgery | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, self-funded | Venous thromboembolism | | | | |
ChiCTR1800016229: A randomized controlled trial for assessing the effectiveness and safety of patients with abdominal or pelvic tumors receiving prolonged postoperative thromboprophylaxis |
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| Not yet recruiting | 4 | 682 | | standard prolonged thromboprophylaxis with low molecular weight heparin till 4 weeks after operation ;routine non-standard postoperative thromboprophylaxis | Ruijin Hospital, Shanghai Jiaotong University School of Medicine; Ruijin Hospital, Shanghai Jiaotong University School of Medicine, self-financing | venous thromboembolism | | | | |
ChiCTR1800019890: Effect of gene polymorphism on the efficacy of direct oral anticoagulant therapy in patients with venous thromboembolism |
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| Not yet recruiting | 4 | 200 | | Dabigatran ;Rivaroxaban | Shanghai Pulmonary Hospital; Shanghai Pulmonary Hospital, shanghai pulmonary hospital | venous thromboembolism | | | | |
ChiCTR1900023372: Efficacy and safety of low molecular weight heparin in the prevention of acute necrotizing pancreatitis complicated with portal vein thrombosis: a multicenter, prospective, double-blind, randomized controlled trial |
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| Not yet recruiting | 4 | 160 | | Low molecular weight heparin ;Saline | The First Affiliated Hospital of Nanchang University; The First Affiliated Hospital of Nanchang University, Self-financing | Acute necrotizing pancreatitis | | | | |
2020-005467-31: Effect of Tinzaparin on inflammatory biomarkers during the acute phase of deep vein thrombosis Effet de la Tinzaparine sur les marqueurs inflammatoires sériques à la phase aiguë de la thrombose |
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| Not yet recruiting | 4 | 12 | Europe | Tinzaparine, Injection, INNOHEP | CHU Amiens-Picardie, CHU Amiens-Picardie | acute phase of deep vein thrombosis phase aiguë de la thrombose, acute phase of deep vein thrombosis phase aiguë de la thrombose, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
FILMS, ChiCTR2000035142: Fondaparinux Sodium for Vascular Surgery Inpatients Thromboprophylaxis versus Low-molecular-weight Heparins: A Prospective, Multicenter, Randomized Controlled Trial |
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| Not yet recruiting | 4 | 940 | | Sulfonda heparan sodium, 2.5mg, QD, IH ;enoxaparin, 4000IU, QD, IH | General Hospital of Tianjin Medical University; General Hospital of Tianjin Medical University, China Foundation for Health Promotion | venous thromboembolic prophylaxis | | | | |
| Terminated | 4 | 800 | Europe | Apixaban, Apixaban and positive d-dimer | Arianna Anticoagulazione Foundation | Venous Thromboembolism, Anticoagulants | 09/21 | 01/23 | | |
ChiCTR2000029081: Prospective Randomized Trial on Efficacy of Rivaroxaban and Wafarin on Preventing Vein Thromboembolism in Nephrotic Syndrome |
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| Not yet recruiting | 4 | 144 | | 10mg/d Rivaroxaban on preventing vein thromboembolism ;Warfarin targeting INR 2-3 on preventing vein thromboembolism | Peking Union Medical College Hospital, Chinese Academy of Medical Science; Peking Union Medical College Hospital, Chinese Academy of Medical Science, Self-supporting | Nephrotic Syndrome | | | | |
ChiCTR1900025948: A clinical study for the efficacy and safety of a multicenter, open, randomized, low-dose aspirin for prevention of deep vein thrombosis after PICC catheterization |
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| Recruiting | 4 | 554 | | oral low-dose Aspirin ;No oral aspirin | The Fifth Affiliated of Sun Yat-Sen University; The Fifth Affiliated of Sun Yat-sen University, The Fifth Affiliated of Sun Yat-Sen University | Deep Vein Thrombosis | | | | |
2019-002323-15: Pre- vs. postoperative thromboprophylaxis for liver resection – a prospective, multicenter, randomized controlled trial |
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| Not yet recruiting | 4 | 1012 | Europe | Fragmin, Klexane, Solution for injection in pre-filled syringe, Fragmin, Klexane | Helsinki University Hospital, Helsinki University Hospital and Syöpäsäätiö (Finnish Cancer Foundation) | Venous thromboembolism, Venous thromboembolism, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
ChiCTR2100042259: Effectiveness and safety of sulfonate in the prevention of venous thromboembolism after hip fracture |
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| Recruiting | 4 | 90 | | Sulfonda liver decanodium 2.5mg, subcutaneous injection. ;Enoxaparin sodium 4000IU (Sanofi) subcutaneous injection ;Oral rivaroxaban 10mg (Bayer) | Affiliated Hospital of North Sichuan Medical College; Affiliated Hospital of North Sichuan Medical College, Sichuan Medical Association | Hip fracture | | | | |
ChiCTR2100049891: Sequential use of different anticoagulant drugs for prevention of venous thromboembolism in hospitalized patients with traumatic fractures: a multi-center, prospective and practical clinical study |
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| Not yet recruiting | 4 | 7414 | | Fondaparinux (during hospitalization) + Rivaroxaban/low molecular weight heparin/Fondaparinux (after discharge); low molecular weight heparin (during hospitalization) + rivaroxaban/low molecular weight heparin/fondaparinux (after discharge) | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, China Red Cross Foundation | Prevention of venous thromboembolic events | | | | |
ChiCTR2100047815: Efficacy of Sichong tablet in the treatment of deep venous thrombosis in the Internet plus mode |
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| Recruiting | 4 | 300 | | WeChat official account ;nothing ;nothing ;Oral administration of Sichong tablets | Affiliated Hospital of Shandong University of traditional Chinese Medicine; Affiliated Hospital of Shandong University of traditional Chinese Medicine, Shandong Administration of traditional Chinese Medicine | Deep venous thrombosis of lower extremity | | | | |
ChiCTR2000036497: A randomized controlled trial for assessing the effectiveness and safety of patients with malignant abdominal or pelvic tumors receiving prolonged postoperative thromboprophylaxis |
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| Not yet recruiting | 4 | 682 | | 对照组 ;试验组 | Ruijin Hospital, Shanghai Jiaotong University School of Medicine; Ruijin Hospital, Shanghai Jiaotong University School of Medicine, self-finanacing | venous thromboembolism | | | | |
NCT03988101: Role of Statin in Venous Dysfunction in Patients With Venous Thromboembolism Event |
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| Recruiting | 4 | 100 | RoW | Rosuvastatin 20mg, Control | Yonsei University | Venous Thromboembolism, Dyslipidemias | 11/22 | 11/22 | | |
NCT02342444: Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD) |
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| Recruiting | 4 | 606 | US | Enoxaparin Sodium Injection 30 mg BID, Lovenox, Enoxaparin Sodium Injection 40 mg QD | Oregon Health and Science University | Trauma, Surgery, Deep Vein Thrombosis (DVT), Thromboembolic Events | 12/24 | 03/25 | | |
ChiCTR2100042205: A comparative study on prevention of lower extremity deep vein thrombosis after hip/knee replacement using sulfonate and ntrexapparin calcium based on ERAS concept |
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| Recruiting | 4 | 80 | | Sulfodagan-Gui Sodium Injection (Jiangsu Hengrui Company) 2.5mg was injected subcutaneously 12 hours after operation ;Subcutaneously injected Natreheparin calcium 57 IU/kg 6 hours after operation | Affiliated Hospital of North Sichuan Medical College; Affiliated Hospital of North Sichuan Medical College, Sichuan Medical Association | Osteoarthritis;Necrosis of femoral head | | | | |
ChiCTR2100041689: Study on the correlation between the risk of thrombosis and bleeding after hip and knee replacement and the effect of anticoagulation |
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| Recruiting | 4 | 600 | | aspirin ;Enoxaparin ;Rivaroxaban | The Second Affiliated Hospital of Kunming Medical University; The Second Affiliated Hospital of Kunming Medical University, The Second Affiliated Hospital of Kunming Medical University | Hip and knee replacement, deep vein thrombosis | | | | |
2023-000150-20: The effect of exercise on function and concentrations of a single dose of unfractionated heparin Effekten af fysisk aktivitet på optagelse og virkning af ufraktioneret heparin |
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| Ongoing | 4 | 15 | Europe | Heparin "LEO", injektionsvæske, opløsning 5.000 IE/ml, Solution for injection in vial, Heparin "LEO", injektionsvæske, opløsning 5.000 IE/ml | Bispebjerg-Frederiksberg Hospital, Department of Clinical Pharmacology, Bispebjerg-Frederiksberg Hospital | Unfractionated heparin is used for the prevention and treatment of deep vein thrombosis and complications hereof Ufraktioneret heparin bruges til forebyggelse og behandling af dyb venetrombose og komplikationer til dette, Unfractionated heparin is used for the prevention and treatment of deep vein thrombosis and complications hereof Ufraktioneret heparin bruges til forebyggelse og behandling af dyb venetrombose og komplikationer til dette, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
| Completed | 4 | 85 | Europe | Enoxaparin | Tampere University Hospital, Heart Hospital, Tampere University Hospital | Venous Thromboembolism, Pulmonary Embolism, Thromboprophylaxis | 03/23 | 03/23 | | |
NCT04645550: Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT） |
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| Completed | 4 | 120 | RoW | Apixaban, ELIQUIS, Warfarin, Warfarin Sodium, Athrombine, COUMADIN, PANAWARFIN, Aspirin, Acenterine, Acetard, Acetophen, Dipyridamole, Gardoxin, Coribon, Curantyl, Dilaplus, Low molecular weight heparin, Fraxiparine | Northern Jiangsu People's Hospital | Cirrhosis, Splenectomy; Status, Venous Thrombosis, Hypertension, Portal | 03/23 | 03/23 | | |
Ésquilo, NCT05303818: Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer |
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| Not yet recruiting | 4 | 68 | RoW | Rivaroxaban 10 MG | Hospital do Servidor Publico Estadual | Deep Venous Thrombosis, Colonic Cancer | 06/23 | 06/24 | | |
ONCO DVT, NCT03895502: Optimal Duration of Anticoagulation Therapy for Isolated Distal Deep Vein Thrombosis in Patients With Cancer Study |
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| Completed | 4 | 605 | Japan | 12-month Edoxaban, 3-month Edoxaban | Takeshi Morimoto | Venous Thrombosis, Neoplasms, Anticoagulant | 06/23 | 08/23 | | |
ChiCTR2200063132: Clinical study on changes of coagulation and fibrinolysis system and deep vein thrombosis in Tibetan patients after major spinal surgery |
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| Not yet recruiting | 4 | 60 | | Tranexamic acid was injected intravenously 50mg/kg before surgery ;Tranexamic acid was injected intravenously 20mg/kg before surgery ;None | Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region; Hospital of Chengdu Office of People's Government of Tibetan Autonomous Region, Natural Science Foundation of Tibet Autonomous Region (XZ202101ZR0047G) | Lumbar spinal stenosis; Lumbar disc herniation | | | | |
ChiCTR2200063471: Effect of Low-dose vs Standard-dose Rivaroxaban Prophylaxis on Venous Thromboembolism Among Patients Undergoing Knee Arthroplasty: a Randomized Clinical Trial |
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| Not yet recruiting | 4 | 108 | | Rivaroxaban (5 mg po qd) ;Rivaroxaban (10 mg po qd) | The Second Affiliated Hospital of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, Self-funded | Osteoarthritis | | | | |
NCT05001776: Endovenous Laser Ablation in Acute Thrombophlebitis of the Varicose Great Saphenous Vein |
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| Completed | 4 | 105 | RoW | Endovenous laser ablation, Ablation of varicose vein, Fondaparinux Sodium, Anticoagulation | National Medical Research Center for Therapy and Preventive Medicine | Superficial Vein Thrombosis, Endovenous Laser Ablation | 12/23 | 12/23 | | |
ChiCTR2100049014: A multi-center, prospective, real-world study of different anticoagulation strategies to prevent venous thromboembolism in cancer patients |
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| Not yet recruiting | 4 | 1378 | | Fondaparinux ;Low molecular weight heparin | Anhui Cancer Hospital; Anhui Cancer Hospital, chinese red cross foundation | Tumor associated thrombosis | | | | |
| Recruiting | 4 | 650 | Europe | Fludeoxyglucose 18F, 18-Fludeoxyglucose (18FDG) | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Venous Thromboembolic Disease, Respiratory Disease, Pulmonary Disease, Deep Venous Thrombosis, Pulmonary Embolism, Screening, Undefined | 12/23 | 12/23 | | |
NCT05081375: Pre-operative Enoxaparin in the Surgical Management of Multi-trauma Patients Undergoing Orthopedic Surgical Procedures |
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| Terminated | 4 | 6 | US | Enoxaparin Injectable Product, Lovenox, Sodium chloride, Placebo | Valleywise Health | Venous Thrombosis Deep (Limbs), Surgical Blood Loss | 11/23 | 11/23 | | |
NCT03244020: LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology |
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| Enrolling by invitation | 4 | 1434 | US | Aspirin 325mg, ASA, Enoxaparin 40Mg/0.4mL Prefilled Syringe, Lovenox | Massachusetts General Hospital | Sarcoma, Soft Tissue Sarcoma, Bone Sarcoma, Bone Metastases, Venous Thromboembolism, Hematoma, Anticoagulant-induced Bleeding | 12/27 | 07/28 | | |
IDAHeT, NCT04710732: Individual Dose Adjustment of Low-molecular-weight-heparin by Thromodynamics Test. |
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| Recruiting | 4 | 150 | RoW | Standard Enoxaparin 40 mg once-daily before randomization, Standard Enoxaparin 40 mg once-daily after randomization, Escalated Enoxaparin 30 mg twice-daily after randomization, Anti-embolic elastic compression stockings, Thrombodynamic test (TD) | Pirogov Russian National Research Medical University | Venous Thromboembolism | 12/23 | 01/24 | | |
HI-PRO, NCT04168203: Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism |
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| Active, not recruiting | 4 | 600 | US | Apixaban 2.5 MG, Placebo oral tablet | Brigham and Women's Hospital | Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism | 11/23 | 06/25 | | |
ESRETP, ChiCTR2000036790: The efficacy and safety of Rivaroxaban and Enoxaparin for thromboprophylaxis after pulmonary surgery for cancer: a single, randomized, single-blind, parallel control clinical study. |
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| Not yet recruiting | 4 | 740 | | oral take rivaroxaban ;Hypodermic injection of Enoxaparin | Shanghai Pulmonary Hospital; Shanghai Pulmonary Hospital, Shenkang Hospital Development Center of Shanghai | Venous Thromboembolism | | | | |
| Recruiting | 4 | 100 | RoW | r-Hirudin, Thrombexx | MinaPharm Pharmaceuticals | Prophylaxis of Deep Vein Thrombosis | 12/23 | 12/23 | | |
SAFE-SSPE, NCT04263038: Clinical Surveillance vs. Anticoagulation for Low-risk Patients With Isolated Subsegmental Pulmonary Embolism |
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| Recruiting | 4 | 276 | Europe, Canada | Rivaroxaban, Placebo | Drahomir Aujesky, University of Bern, Schweizerischer Nationalfonds, Leiden University Medical Center, The Ottawa Hospital, Bayer | Pulmonary Embolism, Embolism, Embolism and Thrombosis, Lung Diseases, Cardiovascular Diseases, Respiratory Tract Diseases, Venous Thromboembolism, Anticoagulant-induced Bleeding, Bleeding | 05/26 | 05/26 | | |
| Terminated | 4 | 9 | Canada | tinzaparin, Rivaroxaban | Sunnybrook Health Sciences Centre, LEO Pharma, Sunnybrook Research Institute | Deep Vein Thrombosis, Post Thrombotic Syndrome | 01/24 | 01/24 | | |
| Completed | 4 | 229 | Europe, Canada, US, RoW | Apixaban, Standard of Care | Bristol-Myers Squibb, Pfizer | Venous Thromboembolism | 04/24 | 04/24 | | |
COBRRA, NCT03266783: Comparison of Bleeding Risk Between Rivaroxaban and Apixaban for the Treatment of Acute Venous Thromboembolism |
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| Recruiting | 4 | 2760 | Europe, Canada, RoW | Apixaban, Eliquis, Rivaroxaban, Xarelto | Ottawa Hospital Research Institute, Canadian Institutes of Health Research (CIHR), Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network | Venous Thromboembolism | 08/24 | 12/24 | | |
T-REX HMB, NCT06452342: TRanEXamic Acid to Decrease Heavy Menstrual Bleeding in Individuals Anticoagulated for Venous Thromboembolism Pilot Study |
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| Not yet recruiting | 4 | 20 | NA | Tranexamic acid, Cyclokapron, No Tranexamic acid | University Health Network, Toronto, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network | Venous Thromboembolism, Venous Thromboses, Heavy Menstrual Bleeding, Anticoagulants and Bleeding Disorders | 04/26 | 04/26 | | |
ONCO PE, NCT04724460: Optimal Duration of Anticoagulation Therapy for Low-risk Pulmonary Embolism Patients With Cancer |
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| Active, not recruiting | 4 | 177 | Japan | Long DOAC, Short DOAC | Takeshi Morimoto, Bayer Yakuhin, Ltd. | Venous Thrombosis, Neoplasms, Anticoagulants | 09/24 | 12/24 | | |
| Recruiting | 4 | 65000 | Europe | Dalteparin Prefilled Syringe, Tinzaparin profiled syringe | Herlev Hospital | Anticoagulant, Venous Thromboembolism, Prophylaxis, Treatment | 03/25 | 03/25 | | |
PEPPER, NCT02810704: Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement |
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| Recruiting | 4 | 20000 | Canada, US | Enteric Coated Aspirin, Aspirin, Warfarin, Coumadin, Rivaroxaban, Xarelto | Dartmouth-Hitchcock Medical Center, Patient-Centered Outcomes Research Institute, University of Maryland, Baltimore, Brigham and Women's Hospital, Northwestern University, Medical University of South Carolina | Pulmonary Embolism, Venous Thrombosis | 07/25 | 07/25 | | |
ChiCTR2200066819: Benefit and risk assessment of preoperative use of low-molecular-weight heparin to prevent venous thrombosis in elderly patients with unstable intertrochanteric fractures |
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| Not yet recruiting | 4 | 100 | | Low-molecular-weight heparin ;Physiological saline preoperation and LMWH postoperation | Hengyang Central Hospital; Hengyang Central Hospital, Hunan Provincial Health Commission and Hengyang Central Hospital | Unstable intertrochanteric fractures in the elderly | | | | |
ChiCTR2300074296: Rivaroxaban versus no anticoagulation for post-discharge thromboprophylaxis after thoracoscopic surgery for lung cancer: an open-label, multicenter, randomized, controlled trial |
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| Not yet recruiting | 4 | 540 | | Oral rivaroxaban prolongs prophylactic anticoagulation ;none | Shanghai Pulmonary Hospital; Shanghai Pulmonary Hospital, Scientific research fund | Venous Thromboembolism | | | | |
| Recruiting | 4 | 6660 | Europe | Dalteparin Sodium, Tinzaparin Sodium, Enoxaparin Sodium, Rivaroxaban, Apixaban, Dabigatran Etexilate | Imperial College London | Venous Thromboembolism, Varicose Veins | 06/26 | 12/26 | | |
ChiCTR2300069862: The clinical study of direct oral anticoagulant drugs on regulating hypercoagulability of liver cirrhosis to improve prognosis after transjugular intrahepatic portosystemic shunts |
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| Not yet recruiting | 4 | 100 | | Treated with DOACs after TIPS ;without anticoagulants after TIPS | West China Hospital, Sichuan University; West China Hospital, Sichuan University, The study is a prospective randomized controlled study, thus human sample collection and research funds are not involved. | Liver cirrhosis | | | | |
DANNOAC-VTE, NCT03129555: The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism |
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| Recruiting | 4 | 5000 | Europe | Dabigatran Etexilate Oral Capsule, Rivaroxaban Oral Tablet, Edoxaban Oral Tablet, Apixaban Oral Tablet | Herlev and Gentofte Hospital, Danish Society of Cardiology | Deep Vein Thrombosis, Pulmonary Embolism | 03/27 | 03/29 | | |
ChiCTR2300073012: Comparison of curative effect and safety between vascular interventional and endoscopic therapy on the prevention of EGVB in patients with PVT/CTPV |
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| Not yet recruiting | 4 | 120 | | endoscopic sequential therapy ;Vascular interventional therapy | West China Hospital, Sichuan University; West China Hospital, Sichuan University, Popularization and Application Project of Sichuan Health Commission (21PJ027) | portal vein thrombosis/Cavernous Transformation of the Portal Vein | | | | |
