| Venous Thromboembolism |
ACTRN12622000285752: The effect of pre-operative oral antibiotics on post-operative surgical site infections in patients undergoing elective colorectal surgery. |
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| Not yet recruiting | 2 | 500 | | | Mr Asiri Arachchi, Department of Colorectal Surgery, Dandenong Hospital, Monash Health | Surgical Site Infections, Venous thromboembolism, Urinary tract infections, Respiratory infections, Gastrointestinal infections, Mortality | | | | |
| Recruiting | 2 | 600 | | | South East Sydney and Illawarra Area Health Service , Thrombosis and Haemostasis Society of Australia and New Zealand | Cancer-associated thrombosis, Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism | | | | |
2010-019500-23: Therapy with Pegylated Interferon Alfa-2a for Patients with Polycythemia Vera or Essential Thrombocythemia who are Either Hydroxyurea Resistant or Intolerant Or have had Abdominal Vein Thrombosis. Terapia con l'interferone Alfa-2a (PEGASYS) Peghilato per i pazienti con Policitemia Vera o Trombocitemia Essenziale che sono resistenti o intolleranti al trattamento con Hydroxyurea o che hanno avuto una trombosi della vena spalcnica. |
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| Ongoing | 2 | 188 | Europe | Solution for injection, Peginterferon PFS | CONSORZIO MARIO NEGRI SUD, Myeloproliferative Disorders-Research Consortium | High risk polycythemia vera and high risk essential thrombocythemia Policitemia Vera (PV) ad alto rischio o Trombocitemia Essenziale (ET) ad alto rischio, polycythemia vera or essential thrombocythemia Policitemia Vera o Tromcitemia Essenziale, Diseases [C] - Blood and lymphatic diseases [C15] | | | | |
2012-000165-20: Clinical trial to evaluate the results of intravitreal bevacizumab injections in cases of recurrence of macular edema secondary to retinal vein thrombosis previously treated with ozurdex Ensayo Clínico para evaluar los resultados del tratamiento con inyecciones intravítreas de bevacizumab en los casos de recidiva del edema macular secundario a trombosis de vena de retina que ha sido tratado previamente con ozurdex |
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| Ongoing | 2 | 53 | Europe | Solution for infusion, AVASTIN | Fundación para la Investigación biomédica del Hospital Universitario Ramón y Cajal. Madrid, Concedida ayuda a la investigación clínica independiente 2011.MSPI. EC11-136 | Macular edema secondary to retinal vein occlusion Edema macular secundario a oclusiones venosas de retina, Visual loss due to Macular edema after retinal vein occlusion La pérdida de visión por edema macular debido a trombosis venosa de la retina, Diseases [C] - Eye Diseases [C11] | | | | |
2012-002253-30: A phase 2 study of Ruxolitinib in patients with splanchnic vein thrombosis associated with myeloproliferative neoplasm Studio di fase II del Ruxolitinib in pazienti con Trombosi delle Vene Splancniche associata a Neoplasia Mieloproliferativa |
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| Ongoing | 2 | 21 | Europe | Jakafy, Jakafy | UNIVERSITA\' DEGLI STUDI DI FIRENZE, Dipartimento di Ematologia dell’Università degli Studi di Firenze | splanchnic vein thrombosis associated with myeloproliferative neoplasm TROMBOSI SPLANCNICA ASSOCIATA A NEOPLASIA MIELOPROLIFERATIVA | | | | |
2016-003240-37: Study to evaluate the effect of rivaroxaban in patients with advanced liver disease with portal vein thrombosis Estudio para evaluar el efecto del rivaroxaban en pacientes con enfermedad hepática en fase avanzada con trombosis portal |
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| Ongoing | 2 | 134 | Europe | Film-coated tablet, Xarelto® | Fundación para la Investigación Biomédica Hospital Ramón y Cajal, Carlos III Health Institute (National Health System) | Liver cirrhosis and portal vein thrombosis Cirrosis hepática y trombosis de la vena porta, Liver disease in advanced stage, with the possibility of developing portal vein thrombosis (occlusion of the vein that carries blood to the liver) Enfermedad hepática en fase avanzada, con posibilidad de desarrollar trombosis en la vena porta (oclusión de la vena que lleva la sangre al hÃgado), Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2016-005184-13: METRO STUDY - MESOGLYCAN VERSUS PLACEBO INSECONDARY PREVENTION OF SURFACE VEIN THROMBOSIS STUDIO METRO - MESOGLICANO VERSUS PLACEBO NELLAPREVENZIONE SECONDARIA DELLA TROMBOSI VENOSA SUPERFICIALE |
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| Ongoing | 2 | 650 | Europe | Prisma, [B01AB], Capsule, hard, PRISMA | MEDIOLANUM FARMACEUTICI S.P.A., Mediolanum Farmaceutici s.p.a. | patients with SVT of the lower limbs that have completed the acutephase treatment cycle pazienti affetti da TVS degli arti inferiori che abbiano completato il ciclodi terapia della fase acuta, Patients with Superficial Vein Thrombosis of the lower limbs that havecompleted the acute phase treatment cycle pazienti affetti da Trombosi Venosa Superficiale degli arti inferiori cheabbiano completato il ciclo di terapia della fase acuta, Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2019-000133-39: A proof-of-concept study to evaluate 99mTechnetium radiolabeled Fucoidan as a diagnostic modality for thrombosis |
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| Ongoing | 2 | 12 | Europe | Fucoidan, radiolabelled solution for IV injection, Solution for injection | Academic Medical Center, European Union | Deep vein thrombosis, A blood clot in the leg, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01] | | | | |
2019-001723-12: Aspirin® plus rivaroxaban versus rivaroxaban alone for the prevention of venous stent thrombosis in patients with post-thrombotic syndrome (long-term condition associated with redness, swelling, leg pain, and ulcers as a results of deep vein thrombosis) |
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| Not yet recruiting | 2 | 316 | Europe | Aspirin protect 100 mg, Film-coated tablet, Aspirin protect 100 mg | Universitätsspital Zürich, Klinik für Angiologie, Universitätsspital Zürich, Klinik für Angiologie, Bayer (Schweiz) AG, BARD Medica S.A. | Post-thrombotic syndrome, Post-thrombotic syndrome is a long-term complication of a deep vein thrombosis. It may include following symptoms: pain, swelling, itching , red/brown skin discoloration and ulcer at the affected leg., Diseases [C] - Cardiovascular Diseases [C14] | | | | |
2020-002210-41: Screening for occult malignancy using Positron Emission Tomography/Computed Tomography (FDG PET/CT) in patients with unprovoked venous thromboembolism Intérêt de la Tomographie par Emission de Positons dans le dépistage du cancer chez les patients atteints de maladie veineuse thromboembolique non provoquée. |
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| Not yet recruiting | 2 | 1276 | Europe | Fludesoxyglucose (18F), Injection, FLUDESOXYGLUCOSE (18F)-CURIUM | CHRU de Brest, CHRU de Brest | Embolism venous Neoplasm malignant Maladie thromboembolique veineuseCancer, Embolism venous Neoplasm malignant Maladie thromboembolique veineuseCancer, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01] | | | | |
ChiCTR2000031649: A prospective, randomized, controlled study of rivaroxaban in the prevention of venous thrombosis in patients with deep vein catheterization chemotherapy for breast cancer |
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| Completed | 2 | 200 | | rivaroxaban 10mg.po.qd ;Without preventive anticoagulant | Beijing Chaoyang District San Huan Cancer Hospital; Beijing Chaoyang District San Huan Cancer Hospital, Apply for funds from chaoyang district science and technology commission | Venous thrombosis of breast cancer | | | | |
NCT05189002: A Study to Evaluate Dimolegin in Prevention of Thromboembolic Complications During Knee Replacement |
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| Active, not recruiting | 2 | 240 | RoW | Dimolegin 40 mg, DD217, Dimolegin 60 mg, Fragmin, Dalteparin sodium | PharmaDiall Ltd. | Venous Thromboembolism | 08/21 | 12/22 | | |
| Withdrawn | 2 | 40 | US | OsciPulse system, Flowtron ACS900 | OsciFlex LLC, University of Pennsylvania | Venous Thromboses, Ischemic Stroke | 12/22 | 03/23 | | |
| Active, not recruiting | 2 | 560 | Europe | Mesoglycan Oral Tablet, Prisma, Placebo Oral Tablet, placebo | Quovadis Associazione, Neopharmed Gentili S.p.A. | Superficial Venous Thrombosis of Leg, Secondary Prevention | 02/23 | 09/24 | | |
NCT05203705: Clinical Study on the Efficacy and Safety of Multiple Oral Administrations of SHR2285 Tablets in Patients Undergoing Elective Total Knee Arthroplasty |
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| Recruiting | 2 | 500 | RoW | SHR2285 tablet, Enoxaparin | Shanghai Hengrui Pharmaceutical Co., Ltd. | Prevention of Venous Thrombosis After TKA | 04/23 | 05/23 | | |
WAVe, NCT03297359: Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism |
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| Terminated | 2 | 92 | Canada | Dalteparin | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network | Cancer, Venous Thromboembolism, Obesity | 11/23 | 11/23 | | |
ChiCTR2300070746: A single arm, single center, prospective clinical study on the efficacy and safety of external radiotherapy (EBRT) combined with lenvatinib in the treatment of hepatocellular carcinoma with portal vein thrombus |
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| Recruiting | 2 | 30 | | radiotherapy in combination with lenvatinib | Zhongshan Hospital Fudan University; Zhongshan Hospital Fudan University, Chinese Anti-Cancer Association | hepatocellular carcinoma | | | | |
PORTAL, NCT05625893: Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion |
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| Recruiting | 2 | 63 | RoW | PBT and atezolizumab/bevacizumab | Samsung Medical Center | Hepatocellular Carcinoma, Portal Vein Thrombosis | 09/23 | 12/25 | | |
ARIVA, NCT04128956: Aspirin® Plus Rivaroxaban Versus Rivaroxaban Alone for the Prevention of Venous Stent Thrombosis in Patients With PTS |
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| Terminated | 2 | 172 | Europe | Aspirin 100mg, Aspirin | University of Zurich, University Hospital Heidelberg, Medical University of Vienna, RWTH Aachen University, Klinikum Arnsberg, University Hospital Freiburg | Venous Thromboses, Stent Stenosis | 02/24 | 02/24 | | |
NCT05166239: HAIC Combine With Lenvatinib and PD-1 Inhibitors for Advanced HCC With PVTT |
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| Recruiting | 2 | 66 | RoW | HAIC, Lenvatinib 1, PD-1 Inhibitors, PD-1, Lenvatinib 2, PD-1 inhibitors 2 | Peking University | Hepatocellular Carcinoma, Portal Vein Thrombosis | 12/23 | 12/24 | | |
NCT06180889: Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty |
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| Recruiting | 2 | 240 | RoW | Enoxaparin, KN060 Low, KN060 Middle, KN060 Hight | Suzhou Alphamab Co., Ltd. | Knee Arthroplasty, Total | 12/25 | 04/26 | | |
| Completed | 2 | 272 | Europe | Rivaroxaban 10 MG Oral Tablet [Xarelto] | Insel Gruppe AG, University Hospital Bern, Bayer, Janssen Pharmaceuticals | Bariatric Surgery | 12/23 | 12/23 | | |
AIRPORT-MPN, NCT04243122: Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients |
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| Completed | 2 | 44 | Canada | Apixaban 2.5 MG Oral Tablet [ELIQUIS], Eliquis, Aspirin 81 mg, Acetylsalicylic acid | Ottawa Hospital Research Institute, Canadian Venous Thromboembolism Clinical Trials and Outcomes Research (CanVECTOR) Network, the Association médicale universitaire de l'Hôpital Montfort (AMUHM), Canadian Hematology Society | Myeloproliferative Neoplasm (MPN), Essential Thrombocythemia (ET), JAK2 Mutation, Polycythemia Vera (PV), Primary Myelofibrosis, Venous Thromboembolism (VTE) | 10/23 | 05/24 | | |
SIRIUS, NCT06149520: A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis |
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| Recruiting | 2 | 255 | Europe, Canada, RoW | BAY3018250, Placebo to BAY3018250 | Bayer | Thrombolysis, Symptomatic Proximal Deep Vein Thrombosis | 08/25 | 10/25 | | |
NCT06220123: A Study to Evaluate the Efficacy and Safety of SHR-2004 Injection in Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery |
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| Not yet recruiting | 2 | 350 | NA | SHR-2004, Enoxaparin Sodium Injection; Rivaroxaban Tablets | Beijing Suncadia Pharmaceuticals Co., Ltd | Preventing Postoperative Venous Thromboembolism in Patients Undergoing Ovarian Cancer Surgery | 06/25 | 07/25 | | |
NCT04295486: Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For VTE Following Total Joint Arthroplasty |
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| Recruiting | 2 | 5478 | US | Aspirin | University of Miami | Venous Thromboembolism | 03/25 | 03/25 | | |
ChiCTR2200058539: A one-arm Phase II clinical study to evaluate the efficacy and safety of TACE, radiotherapy combined with targeting and immune transformation for hepatocellular carcinoma complicated with portal vein thrombus |
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| Not yet recruiting | 2 | 53 | | Conversion therapy of TACE, radiotherapy combined with carrilizumab and Apatinib mesylate | Guangxi Medical University Cancer Hospital; Guangxi Medical University Cancer Hospital, Self-raised | hepatocellular carcinoma | | | | |
NCT05752461: SHR-2004 for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty |
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| Recruiting | 2 | 316 | RoW | SHR-2004 injection, Enoxaparin sodium injection | Beijing Suncadia Pharmaceuticals Co., Ltd | Prevention of Venous Thromboembolism After Knee Arthroplasty | 06/24 | 09/24 | | |
| Not yet recruiting | 2 | 40 | NA | Apixaban | University of Vermont Medical Center, Dartmouth-Hitchcock Medical Center, MaineHealth | Glioblastoma, Astrocytoma, Venous Thromboembolism | 06/24 | 12/24 | | |
NCT04947826: Combination Therapy of HAIC and HLX10 and HLX04 in HCC With Major Portal Vein Tumor Thrombosis |
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| Not yet recruiting | 2 | 100 | NA | HAIC (Hepatic arterial infusion chemotherapy), HLX10 (PD-1 antibody), HLX04 (VEGF antibody), Placebo | Shanghai Zhongshan Hospital, Shanghai Henlius Biotech | Hepatocellular Carcinoma With Major Portal Vein Thrombosis | 07/24 | 07/24 | | |
ROXI-VTE II, NCT06454630: A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants |
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| Not yet recruiting | 2 | 180 | NA | REGN7508, Enoxaparin, Inhixa | Regeneron Pharmaceuticals | Venous Thromboembolism | 03/25 | 03/25 | | |
NCT05618808: A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants |
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| Completed | 2 | 373 | Europe, Canada | REGN9933, Enoxaparin, Lovenox, Apixiban, Eliquis | Regeneron Pharmaceuticals | Venous Thromboembolism | 05/24 | 05/24 | | |
ROXI-CATH, NCT06299111: A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) |
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| Not yet recruiting | 2 | 195 | NA | REGN9933, REGN7508, Placebo | Regeneron Pharmaceuticals | Venous Thromboembolism | 06/26 | 06/26 | | |
NCT05872841: H101 Combined With TACE for Primary Hepatocellular Carcinoma With Portal Vein Thrombosis |
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| Not yet recruiting | 2 | 38 | NA | Recombinant human adenovirus type 5 + TACE, H101+TACE | Tianjin Medical University Cancer Institute and Hospital | Primary Hepatocellular Carcinoma, Portal Vein Thrombosis | 12/24 | 06/25 | | |
API-AHAI, NCT05089227: Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study |
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| Recruiting | 2 | 72 | Europe | treatment "intervention", treatment "standard", biological assessment | Centre Hospitalier Universitaire Dijon | Prolonged Anticoagulation, Venous Thromboembolic Disease, Autoimmune Hemolytic Anemia | 08/25 | 08/25 | | |
NCT04156230: Diagnostic Validity of [18F]GP1 PET for Diagnosing Acute Deep Vein Thrombosis |
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| Recruiting | 2 | 63 | RoW | [18F]GP1 positron emission tomography/computed tomography | Dae Hyuk Moon | Venous Thrombosis | 12/25 | 12/25 | | |
TRAIT, NCT05794165: Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism |
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| Enrolling by invitation | 2 | 314 | US | Thrombate infusion, Placebo | The University of Texas Health Science Center, Houston, Grifols Shared Services North America, Ind. | Trauma Injury, Thromboembolism, Venous Thromboembolism | 11/26 | 03/27 | | |
NCT04504318: Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT |
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| Recruiting | 1/2 | 106 | US | Apixaban 2.5 MG Oral Tablet, Enoxaparin 40Mg/0.4mL Prefilled Syringe | Stanford University | Venous Thromboembolism | 08/24 | 08/24 | | |
NCT04833764: Mechanisms of Deep Vein Thrombosis (DVT) and Vein Wall Fibrosis |
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| Recruiting | 1/2 | 30 | US | Rosuvastatin | Khanh Nguyen | Post-thrombotic Syndrome, Deep Vein Thrombosis Leg | 06/25 | 06/25 | | |
NCT05286320: Phase Ib/II Trial of Combining Pembrolizumab and Lenvatinib With SBRT for HCC Patients With Portal Vein Thrombosis. |
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| Not yet recruiting | 1/2 | 27 | RoW | Lenvatinib/Pembrolizumab plus SBRT combinations, Lenvima, Keytruda | National Taiwan University Hospital | Unresectable Hepatocellular Carcinoma, Pembrolizumab, Lenvatinib, Stereotactic Body Radiotherapy | 09/26 | 09/26 | | |
