Liver Diseases  >>  ribavirin  >>  Phase 4
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35 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
ribavirin / Generic mfg.
NCT00475072: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Ribavirin in Hemophiliac Patients With Chronic Hepatitis C.

Completed
4
14
RoW
peginterferon alfa-2a [Pegasys], ribavirin
Hoffmann-La Roche
Hepatitis C, Chronic
07/06
07/06
NCT00087594: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Copegus (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Enrolled in a Methadone Maintenance Treatment Program.

Completed
4
48
US
peginterferon alfa-2a [Pegasys], ribavirin
Hoffmann-La Roche
Hepatitis C, Chronic
10/06
10/06
NCT00948220: Influence of Antiviral Therapy on Bone Mineral Density and Metabolism in Patients With Chronic Hepatitis C

Completed
4
26
Europe
peginterferon alfa-2a and ribavirin, Pegasys, Copegus
University of Ulm, Hoffmann-La Roche
Hepatitis C, Chronic, Liver Diseases, Virus Diseases
01/07
03/08
TRIC-1, NCT00546442: Treatment Insulin Resistence in HCV G-1 Patient

Completed
4
126
Europe
Metformine, Placebo of metformine
Valme University Hospital
Chronic Hepatitis C
 
01/07
NCT00266318: Study of High Dosage CIFN Plus RBV for HCV Genotype 1 Infected Patients Who Are Nonresponders to Prior Therapy

Completed
4
40
US
Interferon Alfacon-1 and Ribavirin
Beth Israel Medical Center, InterMune
Hepatitis C
05/07
05/07
NCT00275548: Safety and Effectiveness Using Pegasys and Copegus in Recipients of Liver Transplantation With Hepatitis C

Completed
4
12
US
Pegasys, peginterferon alfa-2a, Ro25-8310), Copegus, (ribavirin, Ro20-9963)
Mayo Clinic, Roche Pharma AG
Liver Transplant, Hepatitis C
06/07
04/09
NCT00107653: Latino Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) in Treatment-Naive Patients With Chronic Hepatitis C-Genotype 1.

Completed
4
569
US
Ribavirin, Peginterferon alfa-2a
Hoffmann-La Roche
Hepatitis C, Chronic
09/07
09/07
NCT00001854: Long-Term Therapy With Ribavirin for Chronic Hepatitis C

Completed
4
50
US
Ribavirin
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Hepatitis C
10/07
01/08
NCT00495131: Randomized Trial of 24 or 48 Weeks of Peginterferon Alfa-2a Plus Ribavirin for HCV Genotype 1-infected Patients

Completed
4
308
RoW
Pegylated interferon alfa-2a plus ribavirin, Pegasys plus Robatrol
National Taiwan University Hospital, National Science Council, Taiwan
Hepatitis C, Chronic
06/08
07/08
NCT01258101: A Study of PEGASYS (Peginterferon Alfa-2a) Plus Ribavirin in Patients With Chronic Hepatitis C (CHC), Genotype 2 or 3

Checkmark Data
Jul 2011 - Jul 2011: Data
Completed
4
395
Europe
peginterferon alfa-2a [Pegasys], ribavirin
Hoffmann-La Roche
Hepatitis C, Chronic
07/08
07/08
PHOENIX, NCT00087633: Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) Administered After Liver Transplantation for Hepatitis C.

Completed
4
115
US
peginterferon alfa-2a [Pegasys], Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
10/08
10/08
PILOT-NR, NCT00530972 / 2005-001192-34: Pilot Study of Patients Chronic Hepatitis C in Co-infected HIV Patients Relapsers After Previous Therapies

Completed
4
50
Europe
Peginterferon alfa-2a plus ribavirin adjusted to body weight
Hospital Carlos III, Madrid
Chronic Hepatitis C, HIV Infections
12/08
12/08
NCT00800748 / 2005-003932-23: A Study of Combination Treatment With Peginterferon Alfa-2a (Pegasys) Plus Ribavirin (Copegus) in Participants With Chronic Hepatitis C

Completed
4
372
Europe, RoW
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
01/09
01/09
NCT00353418 / 2005-005506-23: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C (CHC) Genotype 1 and Human Immunodeficiency Virus-1 (HIV-1) Co-infection

Completed
4
415
US
Peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
04/09
04/09
NCT00394277 / 2005-005507-41: A Study of Induction Dosing With PEGASYS (Peginterferon Alfa-2a [40KD]) Plus Copegus in Treatment-Naive Patients With Chronic Hepatitis C

Checkmark EASL 2013: CHARIOT
Apr 2013 - Apr 2013: EASL 2013: CHARIOT
Completed
4
1175
US, Canada, Europe, RoW
peginterferon alfa-2a, Pegasys, Ribavirin, Copegus
Hoffmann-La Roche
Hepatitis C, Chronic
04/09
04/09
NCT00207311: Study for the Treatment of Significant Steatosis With Xenical Followed by Treatment of Hepatitis C With Pegasys/Copegus

Completed
4
30
US
Xenical, Pegasys, Copegus, Xenical (orlistat), Pegasys (PEG-Interferon alpha-2a), Xenicare Program, Xenical placebo, Pegasys (Peg interferon alpha-2a)
Brooke Army Medical Center, Hoffmann-La Roche, The Geneva Foundation
Fatty Liver, Hepatitis C
05/09
05/09
NCT00993122: Ribavirin Pre-treatment Followed by Combined Standard Therapy in Hepatitis C Virus (HCV) Recipients

Completed
4
100
Europe
ribavirin pre-treatment, ribavirin pre treatment, ribavirin priming, Recurrence of hepatitis c, hepatitis c, transplanted patients, ribavirin, HCV
University of Roma La Sapienza
Hepatitis C
04/10
02/12
NCT00192569: Australian Trial in Acute Hepatitis C

Completed
4
167
RoW
Pegylated Interferon alfa 2a, pegasys, Ribavirin (HIV conifected patients only)
Kirby Institute, The University of New South Wales, National Institutes of Health (NIH)
Hepatitis C
06/10
06/10
NCT00686777: Pegylated Interferon (PEG-IFN) Alfa-2b and Low Dose Ribavirin for the Treatment of Chronic Hepatitis C Patients With Genotype 1 High Viral Load and Low Body Weight (Study P05172)(COMPLETED)

Completed
4
75
NA
Pegylated Interferon alfa-2b, SCH 54031, Ribavirin, SCH 18908
Merck Sharp & Dohme LLC
Hepatitis C, Chronic
12/10
12/10
NCT00545233: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus COPEGUS (Ribavirin) With or Without Pioglitazone in Treatment-Naive Patients With Chronic Hepatitis C and Insulin Resistance.

Completed
4
155
US
peginterferon alfa-2a [Pegasys], Pegasys, ribavirin [Copegus], Copegus, Pioglitazone, Actos
Hoffmann-La Roche
Hepatitis C, Chronic
12/10
12/10
Ribados, NCT00484328: Ribavirin, Its Dosing Regime

Completed
4
15
Europe
Ribavirin
Maastricht University Medical Center, Roche Pharma AG
Hepatitis C
12/12
12/12
NCT00977054: Double Filtration Plasmapheresis for Hepatitis C Virus (HCV) Genotype 1 Patients With High Viral Load

Terminated
4
59
RoW
DFPP + Peg-IFN + RBV, DFPP: Plasmaflo + Cascadeflo EC-50W (Asahi), Peg-IFN alfa-2a: Pegasys (Hoffman La-Roche), RBV: Copegus (Hoffman La-Roche), Peg-IFN + RBV
National Taiwan University Hospital, National Science Council, Taiwan, Department of Health, Executive Yuan, R.O.C. (Taiwan)
Hepatitis C
12/12
12/12
NCT01033448: A Study of Extended Therapy of PEGASYS (Peginterferon Alfa-2a) in Combination With COPEGUS (Ribavirin) in Patients With Chronic Hepatitis C and Slow Response

Completed
4
59
RoW
COPEGUS, peginterferon alfa-2a [Pegasys]
Hoffmann-La Roche
Hepatitis C, Chronic
06/13
06/13
NCT01045278 / 2007-001130-13: Hepatitis C in a Cohort of Patients With Maintenance Therapy for Opiate Dependence - Prevalence, Severity and Outcome of Antiviral Therapy

Completed
4
277
Europe
Pegylated interferon-alfa-2b and ribavirin
Region Skane
Hepatitis C
09/13
09/13
NCT01585324 / 2011-001256-10: A Study of The Relationship Between Drop in Hemoglobin and Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Copegus (Ribavirin) and Pegasys (Peginterferon Alfa-2a)

Completed
4
30
Europe
peginterferon alfa-2a [Pegasys], ribavirin [Copegus]
Hoffmann-La Roche
Hepatitis C, Chronic
01/14
01/14
NCT00532701: Peginterferon Alfa-2a and Ribavirin for Genotype 2 Chronic Hepatitis C: Duration and Ribavirin Dose Stratified by RVR

Completed
4
880
RoW
Peg-IFN + WB RBV for 16 weeks, Pegasys plus Copegus, Peg-IFN + LD RBV for 16 weeks, Peg-IFN + WB RBV for 24 weeks, Peg-IFN + WB RBV for 48 weeks, Peg-IFN + LD RBV for 24 weeks
National Taiwan University Hospital, National Science Council, Taiwan, Department of Health, Executive Yuan, R.O.C. (Taiwan)
Chronic Hepatitis C
03/14
03/14
NCT01591460 / 2011-004810-41: A Triple Combination Therapy Study of Boceprevir, Pegasys and Copegus in Previously Untreated Patients With Genotype 1 Chronic Hepatitis C

Completed
4
165
Europe
boceprevir, peginterferon alfa-2a [Pegasys], ribavirin (Copegus]
Hoffmann-La Roche
Hepatitis C, Chronic
06/14
06/14
NCT01405027: Impact of Physician Directed Education on Patient Compliance With Hepatitis C Therapy

Checkmark ACG 2013: OPTIMAL
Sep 2013 - Sep 2013: ACG 2013: OPTIMAL
Completed
4
197
US
Educational Intervention, Peg-Intron, Pegasys, Victrelis, Pegylated interferon alfa 2B, Pegylated interferon alfa 2A, Boceprevir, Ribavirin, Patient education and management skills training
Chronic Liver Disease Foundation, SCRI Development Innovations, LLC, Merck Sharp & Dohme LLC
Chronic Hepatitis C, Genotype 1
07/14
07/14
ATAHC-II, NCT01336010: Treatment of Recently Acquired Hepatitis C Virus Infection

Completed
4
82
RoW
Peginterferon alfa-2a, Pegasys, Ribavirin
Kirby Institute
Acute Hepatitis C
06/15
06/15
VALOR-HCV, NCT02128542: Efficacy and Safety of Sofosbuvir+Ribavirin in Genotype 2 HCV-infected U.S. Veterans With Cirrhosis

Completed
4
66
US
Sofosbuvir, SovaldiĀ®, GS-7977, PSI-7977, RBV
Gilead Sciences
Hepatitis C Virus Infection
06/15
06/15
NCT01686789: Randomized Controlled Open Label Trial of Peg Alpha 2a Interferon and Adjusted-dose of Ribavirin vs. Standard Therapy in the Treatment of Naive Chronic Hepatitis C Patients Infected With Genotype 4

Completed
4
181
RoW
Pegylated interferon alpha-2a
King Abdulaziz Medical City
Chronic Hepatitis C Virus
08/15
08/15
NCT02220868: Sofosbuvir, Ribavirin, for the Treatment of Chronic Hepatitis C Virus Genotype 1 in HIV-Coinfected Patients Receiving Fixed Dose Co-formulation Emtricitabine/ Tenofovir/Cobicistat/Elvitegravir: A Pilot Study

Completed
4
10
US
Sofosbuvir, Ribavirin, and Stribild
Saint Michael's Medical Center
Hepatitis C Infection, HIV Infection
08/15
09/15
DARE-C, NCT01743521: DAA Based Therapy for Recently Acquired Hepatitis C

Completed
4
14
RoW
TPV/PEG-IFN/RBV, Telaprevir brand name: INCIVO, Ribavirin brand name: COPEGUS, PEG-IFN brand name: PEGASYS
Kirby Institute, Janssen-Cilag Ltd.
Hepatitis C, Chronic
11/15
01/16
DARE-C II, NCT02156570: DAA-based Therapy for Recently Acquired Hepatitis C II (DAA = Directly Acting Antiviral)

Completed
4
20
RoW
Sofosbuvir and ribavirin, Sovaldi, Copegus
Kirby Institute
Hepatitis C
08/17
12/17
NCT02304159: Study to Evaluate the Safety and Efficacy of Daclatasvir/Sofosbuvir/Ribavirin for 16 Versus 24 Weeks for HCV Genotype 3 Cirrhotics

Completed
4
39
US
daclatasvir, DCV, BMS-790052, Daklinza, Sofosbuvir, Sovaldi, SOF, Ribavirin, RBV
Tarek I. Hassanein, M.D., FACP, FAG, AGAF
Hepatitis C, Cirrhosis
08/17
08/17

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