Neurologic Manifestations  >>  topiramate  >>  Phase 3
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18 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
topiramate / Generic mfg.
NCT00236418: A Study of the Efficacy and Safety of Topiramate in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Completed
3
80
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures
 
12/96
NCT00266591: A Study of the Efficacy and Safety of Topiramate Treatment in Patients With Epilepsy

Completed
3
51
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures
 
04/97
NCT00236704: A Study of the Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures

Completed
3
80
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures
 
12/99
NCT00236886: Prospective Pilot Study on Metabolism and Weight Changes in Topiramate-Treated Epilepsy Patients

Completed
3
49
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Epilepsies, Partial, Epilepsy, Generalized, Seizures
 
06/00
NCT00236743: A Study of the Effectiveness and Safety of Topiramate in the Treatment of Children With Epilepsy

Completed
3
90
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Epilepsies, Partial, Seizures
 
10/00
NCT00236717: A Study of the Effectiveness and Safety of Topiramate Compared With a Standard Therapy in Patients Newly Diagnosed With Epilepsy

Completed
3
865
US
Topiramate; Carbamazepine; Valproate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures
 
11/00
NCT00236756: A Study of the Efficacy and Safety of Topiramate as an add-on Therapy in the Treatment of Epilepsy Patients With Lennox-Gastaut Syndrome

Completed
3
100
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures
 
02/01
NCT00253175: A Study of the Effectiveness and Safety of Topiramate for the Prevention of Migraine

Completed
3
211
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Ortho-McNeil Neurologics, Inc.
Vascular Headaches, Migraine
 
12/01
NCT00230698: A Study of the Effectiveness and Safety of Topiramate Monotherapy in Patients With Recently Diagnosed Partial-Onset Seizure

Completed
3
451
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Epilepsies, Partial, Seizures
 
08/02
NCT00236509: A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine

Completed
3
763
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Migraine, Common Migraine, Classic Migraine, Headache
 
09/02
NCT00236561: A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine

Completed
3
786
US
topiramate, propranolol
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Migraine, Common Migraine, Classic Migraine, Headache
 
12/02
NCT00231556: A Study on Safety and Efficacy of Two Doses of Topiramate as Monotherapy in the Treatment of Newly Diagnosed or Recurrent Epilepsy

Completed
3
750
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Epilepsy, Seizures, Epilepsies, Partial, Epilepsy, Generalized, Epilepsy, Tonic-Clonic
 
09/03
NCT00236496: A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause.

Completed
3
223
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Ortho-McNeil Neurologics, Inc.
Essential Tremor
 
02/04
NCT00210821: Comparing the Safety and Effectiveness of Topiramate With the Safety and Effectiveness of Amitriptyline in Preventing Migraine Headaches

Completed
3
347
US
topiramate
Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Ortho-McNeil Neurologics, Inc.
Migraine, Headache
 
11/05
NCT00210535: A Study of the Effectiveness and Safety of Topiramate for the Prevention of Migraine Attacks in Children

Completed
3
110
US
Topiramate; Placebo
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Migraine, Vascular Headaches
 
11/06
NCT00113815: Topiramate as Adjunctive Therapy in Infants 1-24 Months for the Control of Partial Onset Seizures

Completed
3
118
US, Canada, Europe, RoW
topiramate, placebo
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Partial Seizure Disorder, Epilepsy, Seizures
06/07
11/07
NCT00563459: Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy.

Terminated
3
89
US
carisbamate, topiramate, levetiracetam
SK Life Science, Inc.
Epilepsy, Seizures
04/10
04/10
NCT01581281: The Childhood and Adolescent Migraine Prevention Study

Terminated
3
488
US
Amitriptyline, Topiramate, Placebo
Children's Hospital Medical Center, Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS)
Migraine, Migraine Disorders, Headache
04/15
01/16

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