Recruiting

N/A

100

 

normal labor ;abnormal labor

Guangzhou Women and Children's Medical Center; Guangzhou Women and Children's Medical Center, Departmental finance

ischemia-reperfusion of myometrium during labor

 

 

Enrolling by invitation

N/A

200

NA

Istituto di Neuroscienze Consiglio Nazionale delle Ricerche, Careggi Hospital, University of Florence

Acute Ischemic Stroke, Reperfusion Injury, Cerebral Edema, Hemorrhagic Transformation Due to Acute Stroke, Animal Model

05/20

03/23

Recruiting

N/A

12

 

N/A

Shanghai Tongren Hospital; Shanghai Tongren Hospital, National Natural Science Foundation of China (81873540)

Myocardial infarction

 

 

Completed

N/A

80

 

Low central venous pressure technology ;normal CVP

Hu'nan Cancer Hospital; Hu'nan Cancer Hospital, self-funded

Liver cancer

 

 

Recruiting

N/A

40

 

cardiac surgery

Renmin Hospital of Wuhan University; Renmin Hospital of Wuhan University, Self-financing

Diabetic myocardial ischemia reperfusion injury

 

 

Recruiting

N/A

120

 

SVV 3%~5% ;SVV 6%~9% ;SVV 10%~13%

The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital); The First Affiliated Hospital of University of science and technology of China (Anhui Provincial Hospital), Application research of Anhui Provincial public welfare technology on linkage projects

Knee replacement

 

 

Recruiting

N/A

90

RoW

remote ischemic preconditioning, Sham remote ischemic preconditioning

Assiut University

Ischemia Reperfusion Injury

01/22

03/22

Recruiting

N/A

100

 

None ;No

Affiliated Hospital of Southwest Medical University; Affiliated Hospital of Southwest Medical University, Scientific research subject

Myocardial Ischemia- reperfusion Injury

 

 

Completed

N/A

250

US

Rohan Dharmakumar

06/24

06/24

Recruiting

N/A

60

 

general anesthesia ;General anesthesia combined with nerve block

Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University; Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University, self-funded

Lower limb surgery in children

 

 

Not yet recruiting

N/A

120

 

N-acetylcysteine ;Normal saline

Tianjin Medical University General Hospital; Zhongnan Hospital of Wuhan University, The row surface of the State Natural Science Fund projects

liver cancer

 

 

Recruiting

N/A

40

Europe

MAP increased to optimize cerebral blood flow, MAP between 65 and 85 mmHg

Centre Hospitalier le Mans

Cardiac Arrest, Cerebral Lesion, Ischemic Encephalopathy, Ischemic Reperfusion Injury

09/22

09/22

Active, not recruiting

N/A

200

Europe

Selective intracoronary hypothermia + PPCI, Selective intracoronary hypothermia, Standard PPCI

Catharina Ziekenhuis Eindhoven, Abbott, Golden Jubilee National Hospital, Onze Lieve Vrouwziekenhuis Aalst, Rigshospitalet, Denmark, Örebro University, Sweden, Skane University Hospital, University of Belgrade, Mid and South Essex NHS Foundation Trust

Acute Myocardial Infarction, Reperfusion Injury

09/22

06/23

Recruiting

N/A

30

RoW

Retrograde renal graft reperfusion, Venous reperfusion, Conventional antegrade renal graft reperfusion (without retrograde reperfusion), Arterial reperfusion

West Kazakhstan Medical University

Kidney Transplantation, Ischemic Reperfusion Injury, Reperfusion

12/22

03/23

Completed

N/A

2

RoW

Patients with coronary artery bypass surgery routine procedural administration of cardioplegia solutions, Patients who underwent heart valve surgery without coronary artery disease routine procedural administration of cardioplegia solutions

Tamer cebe, Istanbul University - Cerrahpasa (IUC)

Cardiovascular Diseases, Myocardial Reperfusion Injury

07/23

07/23

Not yet recruiting

N/A

500

 

Nil

the First Affiliated Hospital, School of Medicine, Zhejiang University; the First Affiliated Hospital, School of Medicine, Zhejiang University, the National Natural Science Foundation of China

liver transplantation

 

 

Recruiting

N/A

200

 

Acute isovolumetric hemodilution via radial artery causes ischemic preconditioning ;Acute isovolumetric hemodilution via the internal jugular vein without ischemic preconditioning

Affiliated Hospital of Guangdong Medical University; Affiliated Hospital of Guangdong Medical University, Self-funded

Liver ischemia reperfusion injury

 

 

Recruiting

N/A

86

RoW

Pneumoperitoneum preconditioning, Sham-Pneumoperitoneum preconditioning

Nanjing First Hospital, Nanjing Medical University

Ischemia Reperfusion Injury

06/23

06/23

Not yet recruiting

N/A

 

First Affiliated Hospital of Zhengzhou University; First Affiliated Hospital of Zhengzhou University, self-raised

Myocardial ischemia-reperfusion injury associated with cardiopulmonary bypass

 

 

Not yet recruiting

N/A

68

NA

SMOFlipid, smoflipid 20% lipid emulsion, Normal saline 0.9%

Assiut University

Ischemic Reperfusion Injury

08/23

10/23

Not yet recruiting

N/A

80

 

Inflate and pressurize the left lower limb blood pressure cuff to 200mmHg for 5min, and then deflate for 5min ;The left lower limb adopts the same technique, but the cuff is not inflated

First Affiliated Hospital of Gannan Medical College; First Affiliated Hospital of Gannan Medical College, Self-finance

Hepatectomy

 

 

Not yet recruiting

N/A

180

 

Dexmedetomidine ;Ulinastatin ;Dexmedetomidine and Ulinastatin ;0.9% Saline(placebo)

The First Affiliated Hospital, The Air Force Medical University; The First Affiliated Hospital, Air Force Medical University, None

laparoscopic liver resection

 

 

Recruiting

N/A

270

RoW

No intervention

Qin Zhang

Liver Injury

12/23

09/24

Not yet recruiting

N/A

40

 

Inhalation of sevoflurane before pulmonary artery perfusion ;Total intravenous anesthesia

Wuxi People's Hospital; Wuxi People's Hospital, Wuxi Municipal Health Commission

lung injury

 

 

Recruiting

N/A

108

 

Nil

Dongguan Hospital of Southern Medical University; Dongguan Hospital of Southern Medical University, self-funded

Acute ischemic stroke

 

 

Not yet recruiting

N/A

120

 

Before induction of anesthesia, general anesthesia was performed after ultrasound-guided femoral nerve block ;Before induction of anesthesia, general anesthesia was performed after ultrasound-guided femoral nerve block. Dexmedetomidine 0.8μg/kg was pumped intravenously for 10min 15min before induction of anesthesia, and then continued to be infused at 0.5μg/ (kg·h) until 30min before the end of surgery ;Before induction of anesthesia, ultrasound-guided femoral nerve block was performed, and then general anesthesia was performed. After induction of anesthesia, orthopedic tourniquet was tied and inflated to 200 mmHg(1 mmHg=0.133 kPa) for 5 min and deflated for 5 min, and three cycles were repeated ;An orthopedic pressure tourniquet was placed on the lower extremity 24 h before surgery and inflated to 200 mmHg for 5 min and deflated for 5 min. Three cycles were repeated

The Third Hospital of Hebei Medical University; The Third Hospital of Hebei Medical University, 2022 Provincial Excellent Talents Program funded by the Government (Leader)

Ischemia-reperfusion injury

 

 

Not yet recruiting

N/A

40

Europe

3-hydroxybuturate

University of Aarhus, Aarhus University Hospital

Heart Failure, Ischemia Reperfusion Injury, Mitochondrial Pathology

01/24

01/24

Not yet recruiting

N/A

30

NA

Thermogard XP3, intravascular hypothermia treatment

Liping Liu

Ischemic Stroke, Revascularization, Endovascular Treatment, Reperfusion Injury

03/24

03/24

Not yet recruiting

N/A

35

Europe

Mechanical ischemic preconditioning of diep-type flap

Assistance Publique - Hôpitaux de Paris, INSERM Bichat hospital

Breast Cancer

05/24

05/24

Recruiting

N/A

16

US

autologous mitochondria transplantation

Boston Children's Hospital

Extracorporeal Membrane Oxygenation Complication

06/24

06/25

Not yet recruiting

N/A

160

 

None ;None ;None

Nanfang Hospital of Southern Medical University; Nanfang Hospital of Southern Medical University, National Natural Science Foundation of China

Sepsis caused by intestinal ischemia-reperfusion injury

 

 

Recruiting

N/A

300

RoW

TENS

Bakulev Scientific Center of Cardiovascular Surgery, State Budget Public Health Institution Scientific Research Institute - Ochapovsky Regional Clinical Hospital

Vagus Nerve Stimulation, Acute Coronary Syndrome, Ischemia Reperfusion Injury

09/24

12/25

Recruiting

N/A

300

RoW

multimodal magnetic resonance imaging or computed tomography, blood samples collection, neurological examination

Second Affiliated Hospital, School of Medicine, Zhejiang University

Stroke, Cerebral Venous System, Reperfusion Injury

12/24

12/25

Not yet recruiting

N/A

100

NA

Extracorporeal cardiac shock wave therapy(ECSW)

The First Affiliated Hospital of Kunming Medical College

Myocardial Reperfusion Injury, Treatment Outcome, Prognosis, ST Elevation Myocardial Infarction

12/24

12/24

Not yet recruiting

N/A

40

 

Tocilizumab ;Normal saline

Renji Hospital Affiliated to Shanghai Jiao Tong University Medical College ; Renji Hospital Affiliated to Shanghai Jiao Tong University Medical College, None

Kidney transplant

 

 

Recruiting

N/A

100

Europe

Subcutaneous blood glucose monitoring device

Instituto de Investigación Hospital Universitario La Paz

Cerebral Infarction

04/25

04/25

Recruiting

N/A

1200

RoW

Remote Ischaemic Conditioning (RIC), Sham-control

University of Cape Town, Groote Schuur Hospital, South Africa, Uganda Heart Institute, Mombasa Hospital, Kenya, Coast General Teaching Hospital, Kenya, Kenyatta National Hospital, Al Shaab Teaching Hospital, Sudan, Sudan Heart Centre, Sudan, Aliaa Specialist Hospital, Sudan, Medani Heart Centre, Sudan, Al Saha Specialised Hospital, Sudan, Omdurman Hospital, Sudan, Victoria Hospital, South Africa, George Hospital, South Africa, Charlotte Maxeke Hospital, South Africa, Tshepong Hospital, South Africa, Wentworth Hospital, South Africa, Grey's Hospital, Universitas Academic Hospital, South Africa, University College, London, Royal Care international Hospital, Sudan, Nairobi West Hospital, Kenya

STEMI, Remote Ischaemic Conditioning, Myocardial Reperfusion Injury

12/25

12/25

Recruiting

N/A

80

 

placebo ;Yixin Decoction

Shuguang Hospital affiliated with Shanghai University of TCM; Shuguang Hospital affiliated with Shanghai University of TCM, Shanghai Municipal Health Commission

myocardial ischemia reperfusion injury

 

 

Not yet recruiting

N/A

40

 

Professor Igor Konstantinov, National Health and Medical Research Council (NHMRC)

Cardiopulmonary by-pass surgery-associated ischemia-reperfusion stress in paediatric patients with congenital heart disease.

 

 

Not yet recruiting

N/A

45

 

Royal Perth Hospital, Royal Perth Hospital Medical Research Fundation

Ischaemic reperfusion injuries

 

 

Not yet recruiting

N/A

100

RoW

ischemic reperfusion injury

The Second Affiliated Hospital of Chongqing Medical University, Second Affiliated Hospital of Third Military Medical University

Postoperative Complications

09/23

11/23