| | N/A | 20 | Europe | AVAPS-AE, AVAPS-AE mode of ventilator therapy | Philips Respironics | Chronic Obstructive Pulmonary Disease | 12/12 | 12/12 | | |
| Active, not recruiting | N/A | 1500 | Canada | | McGill University Health Centre/Research Institute of the McGill University Health Centre, Canadian Institutes of Health Research (CIHR), GlaxoSmithKline, AstraZeneca, Pfizer, Boehringer Ingelheim, Novartis, Takeda, Merck Sharp & Dohme LLC, Almirall, SAS | COPD, Chronic Obstructive Pulmonary Disease | 12/22 | 12/22 | | |