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ACTRN12613000651785: Phase I, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics of RPH-203 Following a Single Dose in Healthy Male Volunteers |
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| Not yet recruiting | 1 | 48 | | | Nucleus Network Limited, R-Pharm | Bone Metastasis , Osteoporosis | | | | |
ACTRN12620000013965: A Study to Compare the Pharmacokinetic Similarity of JHL1266 versus Prolia in Healthy Subjects |
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| Not yet recruiting | 1 | 225 | | | JHL Biotech Australia Pty Ltd., JHL Biotech Australia Pty Ltd. | Osteoporosis | | | | |
ACTRN12623000520639: A Study to Compare the Pharmacokinetic, Pharmacodynamics, safety, Tolerability and Immunogenicity of BP16 versus Prolia (US and EU approved) in Healthy male Volunteers. |
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| Recruiting | 1 | 204 | | | CuraTeQ Biologics Private Ltd., CuraTeQ Biologics Private Ltd. | Osteoporosis | | | | |
| Recruiting | 1 | 44 | | a single dose of GB223 ;a single dose of GB223 ;a single dose of GB223 ;a single dose of GB223 ;a single dose of GB223 | The Fifth Affiliated Hospital of Guangzhou Medical University; Genor Biopharma Co., Ltd, company invest | Treatment of postmenopausal women with osteoporosis and treatment of solid tumor bone metastasis, prevention of bone-related events in patients with solid tumor bone metastasis | | | | |
NCT00548288: Effect of Local Pamidronate in Preventing Bone Loss After Total Hip Arthroplasty |
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| Not yet recruiting | 1 | 40 | Europe | pamidronate | General and Teaching Hospital Celje | Arthroplasty, Mineral Density | | | | |
ChiCTR-TRC-08000120: Randomized controlled study on Traditional Chinese Medicine Yiguyin for osteoporosis in postmenopausal women |
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| Recruiting | 1 | 240 | | Traditional Chinese Medicine Yiguyin, decocted and taking twice a day for 60 days. ;Western Medicine: alpha D3 or alfacalcidol 0.25 μg po. Qd (initial dosage 0.50 μg); calcium agents 1 tablet po. Bid for 60 days | The Eighth Hospital of Wenzhou; Level of the institution：, Self-funded and funded by Wenzhou Scientific and Technical Committee | Osteoporosis in postmenopausal women | | | | |
| Completed | 1 | 288 | | supplied with 900mg calcium and 30g protein per day ;supplied with 900mg calcium per day | Chinese Nutrition Society; Chinese Nutrition Foundation, Chinese Nutrition Foundation | Osteoporosis, Hypertention and Metabolic Syndrome | | | | |
ChiCTR-PRC-09000518: The effects of calcium, vitamin D supplementation on falls and bone health in Chinese postmenopausal women |
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| Completed | 1 | 304 | | added 900 mg calcium or 900 mg calcium plus 800IU vitamin D ;added 900 mg calcium or 900 mg calcium plus vitamin D 800IU per person per day | Institute for Nutrition and Food Safety, Chinese Center for Disease Control and Prevention; Chinese Nutrition Society, Supported by Chinese Nutrition Society 2007 | Osteoporosis, flalling，fracture. | | | | |
NCT02580604: PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2) |
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| Recruiting | 1 | 35 | US | Calcium Chloride/Calcium Gluconate, Placebo | University of Colorado, Denver, National Center for Advancing Translational Sciences (NCATS) | Osteoporosis | 06/24 | 09/24 | | |
ChiCTR1800017552: Study for the Pharmacokinetics, Safety and Immunogenicity of KN012 and Prolia |
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| Not yet recruiting | 1 | 106 | | A single dose of 60 mg will be administered subcutaneously. ;A single dose of 60 mg will be administered subcutaneously. | The First Hospital of Jilin University; Feiyang Biotechnology (Jilin) Co., Ltd., Feiyang Biotechnology (Jilin) Co., Ltd. | Treatment of postmenopausal women with osteoporosis at high risk for fracture | | | | |
ChiCTR-IIC-17012958: Liver kidney in the treatment and application research on the development of postmenopausal osteoporosis |
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| Recruiting | 1 | 30 | | Traditional Chinese medicine | Gansu province hospital of TCM; Gansu province hospital of TCM, The natural science foundation of gansu province | osteoporosis | | | | |
ChiCTR-OID-17014203: Study on open, single center tolerance and pharmacokinetics of recombinant human parathyroid hormone (1-84) for injection in healthy subjects |
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| Not yet recruiting | 1 | 28 | | 25μg ;50μg ;75μg ;100μg | Xiyuan Hospital China Academy of Chinese Medical Sciences; Xiyuan Hospital China Academy of Chinese Medical Sciences, Sponsor | Osteoporosis in menopause women | | | | |
ACTRN12621001521819: Development of an Oral Preparation of Zoledronic Acid for Use in Postmenopausal Osteoporosis/Osteopenia |
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| Completed | 1 | 30 | | | The University of Auckland, The University of Auckland | Osteoporosis, Osteopenia | | | | |
ChiCTR1800015107: The effects of lilalucopeptide combined with alendronate on bone mineral density and serum BGP, s-ctx and BAP levels in patients with type 2 diabetes mellitus and osteoporosis. |
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| Not yet recruiting | 1 | 80 | | Lilalupeptide combined with alendronate sodium therapy. ;Novorapid 30 combined with alendronate sodium. | Gansu Province Hospital of TCM; Gansu province hospital of TCM, Gansu health and family planning commission. | Type 2 diabetes | | | | |
NCT04940845: Comparing of the Pharmacokinetic, Safety and Immunogenicity of HS-20090-2 Injection and Prolia® in Healthy Adults |
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| Recruiting | 1 | 174 | RoW | HS-20090-2, Prolia | Shanghai Hansoh Biomedical Co., Ltd | Postmenopausal Osteoporosis | 06/22 | 06/22 | | |
NCT04435158: A Multiple Dose Study to Evaluate the Effect of SHR-1222 Injection in Postmenopausal Osteoporosis Patients |
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| Completed | 1 | 107 | RoW | SHR-1222, Placebo | Jiangsu HengRui Medicine Co., Ltd. | Osteoporosis | 07/22 | 07/22 | | |
ChiCTR2000038593: The efficacy and adverse reactions of different infusion plan of zoledronic acid in patients with osteoporosis |
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| Not yet recruiting | 1 | 96 | | infuse zoledronic acid 100% in one time ; infuse 20% of zoledronic acid for the first time,infuse the other 80% for the second time ;infuse 50% of zoledronic acid for the first time,infuse the other 50% for the second time ;infuse 80% of zoledronic acid for the first time,infuse the other 20% for the second time | The Second Affiliated Hospital of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, Self-financing | osteoporosis | | | | |
NCT02306187: The Effectiveness of Eldecalcitol in the Bisphosphonate Non-respondered-patients With Osteoporosis |
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| Recruiting | 1 | 100 | Japan | Edirol, Eldecalcitol | Shinshu University | Osteoporosis | 12/22 | 12/24 | | |
ChiCTR2200057644: The effect of milk supplementation on bone health in adults aged 18 to 22 years old |
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| Not yet recruiting | 1 | 106 | | milk supplementation 500 mL per day ;no | Wenzhou Medical University; The Second Affiliated Hospital of Wenzhou Medical University, self-funded | The prevention of osteoporosis | | | | |
NCT05391776: TST002 Intervenous Injection in Postmenopausal Women and Men With Reduced Bone Mineral Density |
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| Recruiting | 1 | 32 | RoW | TST002 Injection, TST002-IgG4, placebo | HJB (Hangzhou) Co., Ltd. | Osteoporosis | 04/23 | 06/23 | | |
NCT05360511: Erythropoietin Gel as an Adjunct to Xenograft in the Surgical Management of Intrabony Periodontal Defects |
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| Completed | 1 | 26 | RoW | particulate xenograft + erythropoietin gel., The mix of xenograft and EPO gel, particulate xenograft, The xenograft alone | Ain Shams University | Periodontal Bone Loss | 09/23 | 10/23 | | |
ChiCTR2200060058: Clinical effect of point application combined with desomumab in the treatment of postmenopausal osteoporosis |
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| Not yet recruiting | 1 | 60 | | Desomumab + basic treatment ;Acupoint sticking + desomumab + basic treatment | The Second Affiliated Hospital of Zhejiang Chinese Medicine University; The Second Affiliated Hospital of Zhejiang Chinese Medicine University, National Natural Science Foundation of China, No.82074183 | Postmenopausal osteoporosis | | | | |
NCT04449211: The Effectiveness in the Treatment of Long Bone Defect Using 3D-printed Implant |
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| Recruiting | 1 | 10 | RoW | Implantation, Bone defect implant | Cho Ray Hospital, Commonwealth Scientific and Industrial Research Organisation, Australia, 3 Dimensional Tech Vision Limited Company | Bone Loss, Defect Limb | 10/23 | 12/23 | | |
ChiCTR2300068318: Effects of high calcium and polyprotein milk on bone metabolism in postmenopausal women: a prospective cohort study |
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| Not yet recruiting | 1 | 150 | | Drink 250 mL high calcium and protein milk in the morning ;Drink 250 mL high calcium and protein milk at night ;Drink 250 mL high calcium and protein milk in the morning and evening | The First Hospital of China Medical University; The First Hospital of China Medical University, self-funded | Osteoporosis | | | | |
NCT05743452: Clinical Trial on the Safety and Efficacy of Magnesium Doped Calcium Silicate 3d Alveolar Bone Repair Unit for Periodontal Bone Defects |
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| Recruiting | 1 | 5 | RoW | GBR with CS@Mg | Second Affiliated Hospital, School of Medicine, Zhejiang University | Alveolar Bone Loss | 12/23 | 12/23 | | |
ACTRN12623000204640: A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ALG-801 in Healthy Postmenopausal Women |
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| Completed | 1 | 32 | | | AliveGen USA, Inc., AliveGen USA, Inc. | Bone loss, Muscle wasting | | | | |
ChiCTR2200058780: Effect of tele-exercise rehabilitation intervention for women with high risk of osteoporotic fractures |
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| Not yet recruiting | 1 | 794 | | Based on the control group, the intervention group will be provided tele-exercise rehabilitation program delivered through telerehab APP ;receive tele-education guidance about OP once a week via telerehab APP and are reviewed outpatient at follow-up time, provided by doctors and nurses | Rehabilitation Medical Center, West China Hospital, Sichuan University; Rehabilitation Medical Center, West China Hospital, Sichuan University, Special Fund of West China Nursing Discipline Development of Sichuan University | Osteoporosis | | | | |
NCT05225857: A First-in-Human Study Evaluating AGA2118 in Men and Postmenopausal Women |
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| Completed | 1 | 90 | RoW | AGA2118, Placebo | Angitia Biopharmaceuticals, Angitia Australia Pty Ltd | Osteoporosis | 01/24 | 01/24 | | |
| Completed | 1 | 208 | Europe, RoW | AVT03, AVT03 proposed Biosimilar to Denosumab, Denosumab, Xgeva | Alvotech Swiss AG | This is a Phase I Study Conducted in Healthy Volunteers | 04/24 | 04/24 | | |
ChiCTR2200063236: Clinical study of Jiawei Yougui pill combined with Jintiange capsule in the treatment of kidney deficiency and blood stasis type OP |
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| Not yet recruiting | 1 | 120 | | Tonifying kidney and activating blood soup ;Jintiange capsule ;Jiawei Yougui pill ;Jiawei Yougui pill combined with Jintiange capsule | Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine; Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Jintiange Young and Middle-Aged Scientific Research Training Fund | Primary osteoporosis | | | | |
NCT05775094: A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis |
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| Recruiting | 1 | 10 | US | Romosozumab | Memorial Sloan Kettering Cancer Center | Multiple Myeloma, Osteoporosis | 03/25 | 03/25 | | |
NCT05930704: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-2017 Injection in Postmenopausal Women |
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| Recruiting | 1 | 45 | RoW | SHR-2017 injection, Placebo | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Osteoporosis | 04/25 | 04/25 | | |
