Not yet recruiting

N/A

92

 

Jianpi Liqi Huashi decoction ;Placebo (1/10 dosage Jianpi Liqi Huashi decoction)

Infectious Disease Hospital of Pudong New Area Shanghai; Infectious Disease Hospital of Pudong New Area Shanghai, Shanghai Pudong New Area Science and Technology Commission

non-alcoholic steatohepatitis

 

 

Recruiting

N/A

240

 

Placebo ;baicalin ;metformin; baicalin plus metformin

the Central Hospital of Qingdao; the Central Hospital of Qingdao, the Central Hospital of Qingdao

non-alcoholic steatohepatitis

 

 

Completed

N/A

410

 

No

not applicable; Level of the institution：, no source of support

live liver donors (LLDs) with and without non-alcoholic steatohepatitis

 

 

Completed

N/A

272

RoW

sleeve gastrectomy, Liver Biopsy

Egyptian Liver Hospital

Obesity, Obesity, Morbid, Bariatric Surgery Candidate, Steatosis of Liver, Steatohepatitis, Nonalcoholic

12/23

05/24

Not yet recruiting

N/A

200

 

There is no drug treatment, and patients are required to strictly control their diet, formulate a professional diet table and exercise strictly ;Diammonium glycyrrhizate enteric capsule 150mg 3/ d, oral, 12 weeks ;Vitamin E 800mg/d, oral, 12 weeks ;Diammonium glycyrrhizate enteric capsule 150mg 3/ d, oral, 12 weeks , Vitamin E 800mg/d, oral, 12 weeks

First Affiliated Hospital, Jilin University; First Affiliated Hospital, Jilin University, First Affiliated Hospital, Jilin University

non-alcoholic steatohepatitis

 

 

Recruiting

N/A

80

US

Hyperpolarized (HP) 13C, HP 13C, Hyperpolarized 13C-Urea, HP13C-urea, copol, Magnetic Resonance Imaging, MRI, MR, Saline Flush

Michael Ohliger, MD PhD, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Non Alcoholic Steatohepatitis, NAFLD, NASH

02/25

02/25

Recruiting

N/A

120

 

Diet

Affiliated Hospital of Hangzhou Normal University; Affiliated Hospital of Hangzhou Normal University, Project subsidy for Social Development Research Initiative design of Hangzhou City

nonalcoholic steatohepatitis

 

 

Recruiting

N/A

200

Europe

Sleeve-Gastrectomy, Roux en Y gastric bypass

RWTH Aachen University

Bariatric Surgery Candidate, Nonalcoholic Steatohepatitis, Obesity

12/20

12/22

Active, not recruiting

N/A

500

Europe

Liver biopsy

Catholic University of the Sacred Heart

NASH - Nonalcoholic Steatohepatitis, NAFLD, Obesity, Obesity, Morbid

01/21

01/23

Recruiting

N/A

20

 

Daily energy intake as 1600-1700kcal for male patients and 1300-1400kcal for female patients combined with Vitamin E soft gel treatment in a dose of 100mg bid,PO. Continue this management 7 days per week for 24 weeks. ;2 days per week with Daily energy intake as 500-600kcal, and the rest 5 days with normal diet(2250kcal/day for male patients and 1800kcal/day for female patients) combined with Vitamin E soft gel treatment in a dose of 100mg bid,PO. Continue this for 24 weeks.

the First Affiliated Hospital of Wenzhou Medical University; the First Affiliated Hospital of Wenzhou Medical University, High Level Creative Talents from Department of Public Health in Zhejiang Province

Non-diabetic Patients with Nonalcoholic Steatohepatitis

 

 

Completed

N/A

160

RoW

Evaluation of the degree of fibrosis and steatosis, Screening for the components of metabolic syndrome, Measurement of serum semaphorin concentrations, Identification of semaphorin gene polymorphisms

University Hospital for Infectious Diseases, Croatia, Croatian Science Foundation

Non-Alcoholic Fatty Liver Disease, Immune Response, Biomarkers, Liver Fibrosis, Non Alcoholic Steatohepatitis

09/21

03/22

Recruiting

N/A

1000

Europe

biopsy-proven NAFLD patients with non-invasive tests of liver fibrosis (blood tests, elastography devices) and biobank

University Hospital, Angers

NAFLD

11/24

12/24

Not yet recruiting

N/A

 

West China Hospital of Sichuan University; Tianjin Third Central Hospital, Philips (China) Investment Co. Ltd.

non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatosis hepatitis (NASH)

 

 

Recruiting

N/A

50

Europe

Ultrasound and Magnetic Resonance

Azienda Unità Sanitaria Locale Reggio Emilia

Non-Alcoholic Fatty Liver Disease, Steatohepatitis, Nonalcoholic, Liver Fibroses

01/22

06/22

Enrolling by invitation

N/A

30

RoW

MLCT Oil, LCT Oil (Corn Oil)

National University Hospital, Singapore, Wilmar International

Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, NAFLD

03/22

03/23

Completed

N/A

84

Europe

oatmeal flakes with prebiotic food supplements, millet flakes

RWTH Aachen University

NASH - Nonalcoholic Steatohepatitis

04/22

04/22

Recruiting

N/A

61

Europe

LiverMultiScan, Multiparametric Magnetic Resonance Imaging (mpMRI)

Perspectum

Liver Diseases, Primary Biliary Cirrhosis, Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, Cirrhosis, Hemochromatosis, Viral Hepatitis, Autoimmune Hepatitis, Primary Sclerosing Cholangitis

06/22

11/22

Recruiting

N/A

400

Europe, Japan, US, RoW

Ultrasound application

Tokyo Medical University

Nonalcoholic Steatohepatitis, Ultrasound, Elastography

07/22

07/22

Active, not recruiting

N/A

533

US

Transient Elastography

Joslin Diabetes Center

Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Fibrosis, Liver, Type 1 Diabetes, Cirrhosis, Liver

08/22

12/24

Active, not recruiting

N/A

40

Europe

Magnetic Resonance Imaging, magnetic resonance spectroscopy, Stable Isotope Study

University of Oxford

Non-Alcoholic Fatty Liver Disease

10/27

10/27

Not yet recruiting

N/A

360

NA

Ultrasound, Fibroscan

Assiut University

Steatohepatitis, Nonalcoholic

09/22

12/22

Recruiting

N/A

160

 

Essentiale combined with Kuhuang Granules placebo ;Essentiale combined with Kuhuang Granules

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine; Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai Shenkang Hospital Development Center

nonalcoholic steatohepatitis

 

 

Active, not recruiting

N/A

164

US

Liver Incytes System, MRE, MRI PDFF, Fibroscan

Sonic Incytes

Non-Alcoholic Fatty Liver Disease (NAFLD), Non-Alcoholic Steatohepatitis (NASH), Liver Fibroses, Liver Steatoses

11/22

07/23

Recruiting

N/A

450

US

ELF Test

University of Kansas Medical Center, Gilead Sciences

Fatty Liver, NAFLD

12/22

12/22

Recruiting

N/A

8

Europe

Margarine

Maastricht University Medical Center, Raisio Group, Unilever R&D, BASF

NASH - Nonalcoholic Steatohepatitis

12/22

12/23

Not yet recruiting

N/A

52

Europe

Plant stanols (3g/day), Benecol (Raisio Nutrition Ltd., Raisio, Finland), Placebo

Maastricht University Medical Center

Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, NAFLD, NASH, NASH - Nonalcoholic Steatohepatitis, Childhood Obesity, Childhood Overweight, Pediatric Obesity

12/22

12/22

Recruiting

N/A

60

 

Electro-acupuncture ;Minimal-acupuncture

Beijing Friendship Hospital, Capital Medical University; Beijing Friendship Hospital, Capital Medical University, self-raised

Non-alcoholic steatohepatitis

 

 

Recruiting

N/A

40

Europe

Liver Fine-Needle Aspiration

Hospices Civils de Lyon

Liver Diseases

01/26

01/26

Completed

N/A

155

US

University of Pittsburgh

Alcoholic Liver Disease, Non-Alcoholic Fatty Liver Disease, Steatohepatitis, Nonalcoholic, Steatohepatitis

04/23

04/23

Completed

N/A

81

US

Positron Emission Tomography (PET) on EXPLORER, PET Scan, Magnetic Resonance Imaging, MRI, Echocardiogram and Electrocardiogram, Echo and EKG or ECG, Blood test, Lab test

University of California, Davis

Non-Alcoholic Fatty Liver Disease (NAFLD), Nonalcoholic Steatohepatitis (NASH)

05/23

05/23

Not yet recruiting

N/A

124

 

Polyene Phosphatidylcholine Capsule ;Xiaozhi Hugan Capsule

The First Affiliated Hospital of He'nan University of Traditional Chinese Medicine; The First Affiliated Hospital of He'nan University of Traditional Chinese Medicine, Special Project of Traditional Chinese Medicine Scientific Research of He'nan Province (No. 2019JDZX2012)

Non-Alcoholic Steatohepatitis

 

 

Active, not recruiting

N/A

10

RoW

NUTRITIONAL EDUCATIONAL INTERVENTION IN FATTY LIVER DISEASE NON-ALCOHOLIC (NAFLD).

Universidade Federal do Paraná

Steatohepatitis, Nonalcoholic, Steatosis, Liver Diseases, Steatohepatitis

06/23

07/24

Active, not recruiting

N/A

20

US

Insulin Resistance, Quality of Life Assessment, Liver Function Test, Radiologic features of NASH, Serologic features of NASH

Brigham and Women's Hospital, American Society for Gastrointestinal Endoscopy, Boston Scientific Corporation

Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty, Non-alcoholic Fatty Liver Disease (NAFLD), Endoscopic Ultrasound, Liver Function, Obesity, Liver Fibroses

09/24

12/24

Recruiting

N/A

700

Europe

ultrasound, elastography, controlled attenuation parameter (CAP), FLI, FIB-4, NFS

University Hospital, Antwerp

NAFLD, Type 1 Diabetes, Cardiovascular Diseases

07/23

07/25

Not yet recruiting

N/A

400

 

N/A ;N/A ;N/A ;N/A

Nanhai hospital, Southern Medical University; Nanhai hospital, Southern Medical University, self-raised

Nonalcoholic steatohepatitis

 

 

Not yet recruiting

N/A

1000

NA

Ultrasound liver assessment, Elastography, Ultrasound attenuation, Sound speed

E-Scopics

Liver Diseases, Liver Cirrhosis, NASH - Nonalcoholic Steatohepatitis, Non-Alcoholic Fatty Liver Disease, Fibrosis, Liver, Steatosis of Liver

09/23

09/23

Active, not recruiting

N/A

40

US

Medication Adherence Problem Solving for Hypertension

Rush University Medical Center

Hypertension, Adherence, Medication

08/24

08/24

Active, not recruiting

N/A

20

Europe

Formula diet

West German Center of Diabetes and Health

Steatohepatitis, Nonalcoholic

12/24

03/25

Completed

N/A

72

RoW

Intermittent calorie restriction, Standard of care

Ewha Womans University Mokdong Hospital

Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis

12/23

12/23

Not yet recruiting

N/A

450

RoW

Genomics (DNA Extraction), Epi-genomics, Proteomics (Glycoproteomics), Salivary Metabolomics, Individualized counselling for behavioural modification

National Research Centre, Egypt

Non-Alcoholic Fatty Liver Disease, Non Alcoholic Steatohepatitis

12/23

04/24

Recruiting

N/A

5000

Canada

routine screening, physician-driven screening

LMC Diabetes & Endocrinology Ltd.

Nonalcoholic Steatohepatitis, Type 2 Diabetes

10/25

10/25

Active, not recruiting

N/A

233

US

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Chronic or Recovered Hepatitis B, Chronic or Recovered Hepatitis C, Chronic or Recovered Hepatitis D, NAFLD, NASH

12/26

12/26

Active, not recruiting

N/A

35

US

Natalie Torok

NASH - Nonalcoholic Steatohepatitis

01/24

03/24

Completed

N/A

80

RoW

Total intravenous anesthesia group, TIVA group, sevoflurane group, SEVO group

Benha University

Laparoscopic Sleeve Gastrectomy

05/24

05/24

Completed

N/A

97

Europe

Ultrasound Attenuation imaging measurement

Hywel Dda Health Board

Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Non-alcoholic Steatohepatitis, Steatosis of Liver

04/24

04/24

Recruiting

N/A

380

RoW

Tanta University

Metabolic- Associated Fatty Liver Disease (MAFLD)

10/24

11/24

Recruiting

N/A

140

RoW

Bariatric surgery, Liver biopsy, Portal vein sampling

National Taiwan University Hospital, Ministry of Science and Technology, Taiwan

Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, Bariatric Surgery

04/24

09/24

Recruiting

N/A

24

US

Magnetic Resonance Imaging (MRI), Ultrasound (US)

University of Wisconsin, Madison

NAFLD, NASH

04/26

04/27

Recruiting

N/A

225

US

Liver Multi Scan, Biopsy

Perspectum

NASH - Nonalcoholic Steatohepatitis

05/24

05/24

N/A

152

US

Magnetic Resonance Elastography (MRE), MRI, Liver biopsy, Intraoperative Biopsy

University of Wisconsin, Madison, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), GE Healthcare, Pfizer, Siemens Medical Solutions, National Center for Advancing Translational Sciences (NCATS)

Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis