Recruiting

4

40

 

75mg/m2Docetaxel+30mg/m2Lobaplatin ;75mg/m2Docetaxel+gemcitabine

Guizhou Cancer Hospital; None, self - provided

Breast Cancer

 

 

Completed

4

6

 

sunitinib or sorafenib combining with gemcitabine plus cisplatin

peking university cancer hospital institute; Peking University Cancer Hospital and Institute, the program for new century excellent talents in university (985-2-085-113)

the collecting duct carcinoma of kidney

 

 

Completed

4

64

 

Integrated TCM treatment regimen include herbal injection(cinobufacini injection or Yan-shu injection), herbal decoction(Ziyin Shengjing Jiedu Fang, Yiqi Jianpi Jiedu Fang, or Yiqi Yangyin Jiedu Fang), and point application(DU 4, RN 4, ST 36 and BL 23). Patients receive herbal injection 20ml/day for 10 days every 21 days and herbal decoction and point application every day throughout the maintenance treatment. Dressings are changed every 24 hours. Cycles were repeated until disease progression, ;Single-agent maintenance chemotherapy regimen: pemetrexed 500mg/m2 vein Infusion on day 1, docetaxel 75mg/m2 vein Infusion on day 1, or gemcitabine 1000mg/m2 vein Infusion on day 1and day 8 every 21 days. Cycles were repeated until disease progression, unacceptable toxicity, or until the patient requested therapy discontinuation.

Longhua Hospital Affiliated to Shanghai University of TCM; Science and Technology Commission of Shanghai Municipality, Science and Technology Commission of Shanghai Municipality

advanced non-small-cell lung cancer (stage IIIB/IV)

 

 

Completed

4

210

 

Vinorelbine +cisplatin ;Etoposide+cisplatin ;Erlotinib ;Vinorelbine +cisplatin of Gemcitabine+cisplatin or Paclitaxel+cisplatin ;Vinorelbine +cisplatin of Gemcitabine+cisplatin or Paclitaxel+cisplatin ;Gemcitabine+cisplatin

First Affiliated Hospital Bengbu Medical College; First Affiliated Hospital of Anhui Traditional Chinese Medical College, Health Department of Anhui Province

Non-Small-Cell Lung Cancer

 

 

Completed

4

112

 

GEM 1000mg/m2 d1, I.V.ggt30-60/min ;Sorafenib 400mg bid po

Henan Cancer Hospital; Level of the institution：, Self financed

Liver cell cancer

 

 

Completed

4

120

 

Group rHuTPO: Patients were treated with recombinant human thrombopoietin(rHuTPO)on d2,d4,d6,d9 of chemotherapy cycle. ;Patients were treated with recombinant human interleukin-11(rHuIL-11)on d9-d15 after chemotherapy

Shanghai Chest Hospital; Sun Yat-Sen University Cancer Center, Shenyang Sunshine Pharmaceutical Co., LTD.

NSCLC

 

 

Recruiting

4

120

 

paclitaxel plus gemcitabine ;paclitaxel sequential gemcitabine

Peking University Cancer Hospital & Institute; Fuling Central Hospital of Chongqing, Peking University Cancer Hospital (Beijing Cancer Hospital)

Breast Cancer

 

 

 

4

28

Europe

Gemcitabine, Oxaliplatin, Gemzar, Eloxatin, Gemzar, Eloxatin

Barts & The London NHS Trust

Locally advanced or metastatic transitional cell carcinoma of the urinary tract

 

 

Ongoing

4

100

Europe

CISPLATINO TEVA, GEMZAR, FARMORUBICINA, XELODA, TAXOTERE, CISPLATINO TEVA, GEMZAR, FARMORUBICINA, XELODA, TAXOTERE

FONDAZIONE CENTRO S. RAFFAELE DEL MONTE TABOR

patients affected by adenocarcinoma at stage III or IV who are candidate to receive upfront chemotherapy according to PDXG or PEXG regimen.

 

 

Recruiting

4

300

 

Nedaplatin+gemcitabine ;cisplatin+gemcitabine

The First Affiliated Hospital of Guangxi Medical University; The First Affiliated Hospital of Guangxi Medical University, self-raised

Advanced lung squamous cell carcinoma

 

 

Not yet recruiting

4

424

 

Taxus capsule ;Pemetrexed ;Taxus capsule ;Gemcitabine

Guanganmen Hospital of Chinese Academy of traditional Chinese Medicine; Guang An Men Hospital of China Academy of Traditional Chinese Medicine, Chongqing Sainuo Biological Pharmaceutical Co., Ltd

non-small cell lung cancer

 

 

Completed

4

100

 

Pharmacological interventions

First Affiliated Hospital of Zhejiang University; First Affiliated Hospital of Zhejiang University, Self-collected funds

Advanced breast cancer

 

 

Not yet recruiting

4

20

 

three - dimensional interstitial radiotherapy, Gemcitabine chemotherapy

The Affiliated Hospital of Southwest Medical University; The Affiliated Hospital of Southwest Medical University, 2017 Sichuan Province health and family planning research projects funded projects

Locally advanced pancreatic cancer

 

 

Recruiting

4

200

 

Oxaliplatin: 85 mg/m2, intravenous infusion, day 1; leucovorin: 400 mg/m2, intravenous infusion, day 1; irinotecan: 150 mg/m2 , Intravenous infusion, day 1; bolus injection of 5-FU: 2400 mg/m2, intravenous infusion, 46 hours; once every two weeks ;Albumin paclitaxel (nab-paclitaxel): 125mg/m2, intravenous infusion (30 minutes), on day 1, 8; gemcitabine (GEM): 1000 mg/m2, intravenous infusion, on day 1, 8; Once every three weeks

Wannan Medical College; Wannan Medical College, Self-financing

Pancreatic cancer

 

 

Not yet recruiting

4

80

 

Intravesical instillation of gemcitabine chemotherapy after bladder tumor surgery ;Intravesical instillation of Pseudomonas aeruginosa injection after bladder tumor operation

Lanzhou University Second Hospital; Lanzhou University Second Hospital, Sub-project of the key research and development project in Gansu Province: “Regularization and diagnosis of cystatin cancer and promotion and application of different urinary diversion procedures”.

Non-muscle invasive bladder cancer

 

 

Recruiting

4

175

Europe

PAXG regimen (cisplatin, nab-paclitaxel, capecitabine, gemcitabine) chemotherapy

IRCCS San Raffaele

Pancreatic Ductal Adenocarcinoma

01/22

01/26

Not yet recruiting

4

240

 

Fasting oral Anlotinib Hydrochloride Capsules 1 capsule daily+GP induced chemotherapy+IMRT concurrent chemotherapy ;GP induced chemotherapy+IMRT concurrent chemotherapy

Wuzhou Red Cross Hospital; Wuzhou Red Cross Hospital, CHIA TAI TIANQING (CTTQ) Pharmaceutical Co., Ltd.

Nasopharyngeal carcinoma

 

 

Not yet recruiting

4

40

 

Apatinib 250mg, po, qd+Gemcitabine, iv, d1, d8+Paclitaxel, iv, d1

First Affiliated Hospital of Zhengzhou University; First Affiliated Hospital of Zhengzhou University, Self-pay

Advanced Hepatosarcomatoid Carcinoma

 

 

Recruiting

4

30

China

gemcitabine + Albumin paclitaxel + Toripalimab monoclonal antibody

West China Hospital of Sichuan University ; West China Hospital of Sichuan University, Latitudinal project

pancreatic cancer

 

 

Recruiting

4

46

 

Carrelizumab combined with gemcitabine

Zhujiang Hospital of Southern Medical University; Zhujiang Hospital of Southern Medical University, Self-raising

Advanced urothelial carcinoma

 

 

Recruiting

4

10

 

Donafenib, Teggio

Fudan University Shanghai Cancer Center; Fudan University Shanghai Cancer Center, self-funded

pancreatic cancer

 

 

Not yet recruiting

4

30

China

Tislelizumab in combination with gemcitabine and oxaliplatin

Jiangsu Provincial People's Hospital ; Jiangsu Provincial People's Hospital, Self-collected

ENKTCL

 

 

Recruiting

4

100

 

Neoadjuvant therapy stage: Sintilimab antibody 200mg, q3w, 3 weeks per cycle, 2-4 cycles, then receive chest CT evaluation. Surgical treatment stage: the patients who have a response to targeting therapy (CR+PR) and the patients who have no response to targeting therapy but can still receive surgical treatment ;Neoadjuvant therapy stage: sintilimab 200mg, q3w, 3 weeks per cycle, 2-4 cycles; bevacizumab, 3 weeks per cycle, 2-4 cycles, then receive chest CT evaluation. Surgical treatment stage: the patients who have a response to targeting therapy (CR+PR) and the patients who have no response to targeting therapy but ;Neoadjuvant therapy stage: PD-1 antibody 200mg, q3w, 3 weeks per cycle, 2-4 cycles; Platinum-based chemotherapy (squamous: carboplatin AUC5, paclitaxel 200mg/m2 or gemcitabine 1000mg/m2; non-squamous: carboplatin AUC5, pemetrexed 500mg/m2), 3 weeks per cycle, 2-4 cycles, then receive chest CT evaluation. Surgical treatment stage:

Department of Thoracic Surgery, Shanghai Pulmonary Hospital; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Shanghai Hospital Development Center

Non-small cell lung cancer

 

 

Active, not recruiting

4

15

US

Aliya Pulsed Electric Fields (PEF) ablation, Nivolumab plus Platinum Doublet Chemotherapy, Carboplatinum, Cipsplatin, Pemetrexed, Gemcitabine, Paclitaxel, Standard of care neoadjuvant therapy, Vinorelbine, Surgical Resection

Galvanize Therapeutics, Inc.

NSCLC

06/24

06/24

Not yet recruiting

4

30

 

Immunotherapy combined with chemotherapy (GP regimen) + carrilizumab

West District of the First Affiliated Hospital of University of Science and Technology of China; West District of the First Affiliated Hospital of University of Science and Technology of China, self-raised

Nasopharyngeal carcinoma

 

 

Recruiting

4

30

China

Tislelizumab in combination with gemcitabine and Sega

The First Affiliated Hospital of Shandong First Medical University (Shandong Qianfoshan Hospital) ; The First Affiliated Hospital of Shandong First Medical University (Shandong Qianfoshan Hospital), Beijing Medical Award Foundation

Advanced pancreatic cancer

 

 

Not yet recruiting

4

20

RoW

Lenvatinib, Adebrelimab, GEMOX（Gemcitabine and oxaliplatin）

Zhiyong Huang

Intrahepatic Cholangiocarcinoma

04/25

05/25

Recruiting

4

36

RoW

Disitamab Vedotin and Gemcitabine

Chunguang yang (101937)

Radical Cystectomy, Urothelial Carcinoma

09/24

09/25

Not yet recruiting

4

200

 

Gemcitabine 1g diluted with 50ml normal saline ;Gemcitabine 1g diluted with 50ml normal saline

The Second Hospital of Tianjin Medical University; The Second Hospital of Tianjin Medical University, Funded by Haosen Company

bladder cancer

 

 

Recruiting

4

40

China

triplizumab combined with paclitaxel ;triplizumab combined with paclitaxe ;triplizumab combined with paclitaxe ;triplizumab combined with paclitaxe

The Second Hospital of Tianjin Medical University ; The Second Hospital of Tianjin Medical University, tianjinshiqingnianrencaituojugongcheng

Urothelial carcinoma

 

 

Not yet recruiting

4

25

NA

Bacillus Calmette Guerin, Gemcitabine

Assiut University

Urothelial Carcinoma Bladder, Sperm Count, Low, Testis; Fibrosis

12/25

12/25

Not yet recruiting

4

41

China

Tislelizumab combined with gemcitabine and cisplatin

Army Medical Center ; Army Medical Center, No

Bladder Cancer