Intrahepatic Cholangiocarcinoma  >>  gemcitabine  >>  Phase 2
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16 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
gemcitabine / Generic mfg.
NCT00084942: Gemcitabine and Capecitabine in Treating Patients With Advanced and/or Inoperable Cholangiocarcinoma or Carcinoma of the Gallbladder

Completed
2
US
capecitabine, gemcitabine hydrochloride
Roswell Park Cancer Institute
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
05/04
11/06
NCT00009893: Combination Chemotherapy in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Completed
2
42
US
fluorouracil, gemcitabine hydrochloride, leucovorin calcium
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
01/05
10/09
SAKK 44/02, NCT00073905: Adjuvant Palliative Capecitabine and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Biliary Tract Cancer

Completed
2
44
Europe
capecitabine plus gemcitabine
Swiss Group for Clinical Cancer Research
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer, Pain
06/06
01/09
NCT00033540: S0202 Gemcitabine and Capecitabine for Unresectable Locally Advanced Metastatic Gallbladder Cancer or Cholangiocarcinoma

Completed
2
57
US
capecitabine, Xeloda (NSC-712807), gemcitabine hydrochloride, Gemzar (NSC-613327)
Southwest Oncology Group, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
04/08
07/11
NCT00075504: Triapine and Gemcitabine Hydrochloride in Gallbladder Cancer

Completed
2
33
US
triapine, 3-AP, OCX-191, gemcitabine, dFdC, difluorodeoxycytidine hydrochloride, Gemzar
National Cancer Institute (NCI)
Stage II Gallbladder Cancer, Stage IIIA Gallbladder Cancer, Stage IIIB Gallbladder Cancer, Stage IVA Gallbladder Cancer, Stage IVB Gallbladder Cancer
01/09
01/09
NCT01534637: Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancer

Completed
2
22
US
aprepitant, Emend, L-754030, MK-0869, ONO-7436, gemcitabine hydrochloride, dFdC, difluorodeoxycytidine hydrochloride, gemcitabine, Gemzar, capecitabine, CAPE, Ro 09-1978/000, Xeloda, fluorouracil, 5-fluorouracil, 5-Fluracil, 5-FU, radiation therapy, irradiation, radiotherapy, therapy, radiation, questionnaire administration, quality-of-life assessment, quality of life assessment, nausea and vomiting therapy, antiemetic support, management of nausea and vomiting, nausea and vomiting management, therapy, nausea and vomiting, vomiting and nausea management, management of therapy complications, complications of therapy, management of
Wake Forest University Health Sciences, National Cancer Institute (NCI), Merck Sharp & Dohme LLC
Extrahepatic Bile Duct Cancer, Nausea, Vomiting, Stage II Pancreatic Cancer, Stage III Pancreatic Cancer, Stage IV Pancreatic Cancer
12/09
08/12
NCT01151761: Phase II SBRT & Chemo for Unresectable Cholangiocarcinoma Followed by Liver Transplantation

Terminated
2
2
US
Stereotactic Body Radiotherapy, External photon radiation, Gemcitabine, Gemzar, Cisplatin, Platinol, Platinol-AQ, Carboplatin, Paraplatin, Paraplatin-AQ, Capecitabine, Xeloda, 5FU, Fluorouracil, Adrucil, Carac, Efudix, Efudex, Fluoroplex, Liver transplantation
Stanford University
Cholangiocarcinoma, Hepatobiliary Neoplasm, Liver Cancer, Bile Duct Cancer, Cancer of Gallbladder
04/12
07/12
VANGOGH, NCT00753675 / 2007-003056-12: Vandetanib Gemcitabine Or Placebo Plus Gemcitabine Or Vandetanib Monotherapy In Advanced Biliary Tract Cancer

Completed
2
174
Europe
ZD6474, Vandetanib, Zactima, Gemcitabine, Gemzar, Placebo matching ZD6474
Genzyme, a Sanofi Company
Biliary Tract Cancer, Gallbladder Cancer, Cancer Of The Extrahepatic Bile Duct, Ampullary Carcinoma
09/12
09/12
NCT01096745: Randomized Trial of Gemcitabine/Cisplatin Versus S-1/Cisplatin in Advanced Biliary Cancer

Terminated
2
78
RoW
Gemcitabine, Cisplatin, Gemcitabine - Gemcitane, Cisplatin - Cispulan, S-1, Cisplatin, S-1; TS-1, Cisplatin ; Cispulan
Gyeongsang National University Hospital, Samsung Medical Center, Dong-A University, Chung-Ang University
Metastatic Biliary Tract Cancer, Locally Advanced Biliary Tract Cancer
03/13
09/13
NCT00832637: Gemcitabine, Oxaliplatin, Tarceva &/or Cisplatin in HCC & Biliary Tree Cancers

Terminated
2
33
US
Cisplatin, Platinol®, Erlotinib, Tarceva®, Gemcitabine, Gemzar®
New Mexico Cancer Care Alliance
Hepatocellular Carcinoma, Cholangiocellular Carcinoma, Cholangiocarcinoma of the Extrahepatic Bile Duct, Bile Duct Cancer, Periampullary Adenocarcinoma, Gallbladder Cancer, Extrahepatic Bile Duct Cancer
06/13
03/17
NCT00919061: Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naive to Systemic Therapy

Completed
2
39
US
Gemcitabine, Cisplatin, Sorafenib
Memorial Sloan Kettering Cancer Center, Bayer
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
03/14
03/14
S0809, NCT00789958: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct

Completed
2
105
US
capecitabine, Xeloda, NSC-712807, gemcitabine hydrochloride, Gemzar, NSC-619927, 3-dimensional conformal radiation therapy, 3D radiotherapy, intensity-modulated radiation therapy, IMRT
Southwest Oncology Group, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
12/14
12/17
NCT02254681: Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC

Terminated
2
6
US
Gemcitabine, Gemzar, Cisplatin, Platinol, low dose radiotherapy
Allina Health System
Intrahepatic Cholangiocarcinoma
09/16
09/16
NCT02181634 / 2015-002066-24: Phase II Trial of Nab-Paclitaxel and Gemcitabine for First-Line Treatment of Patients With Cholangiocarcinoma

Completed
2
74
US, Europe
Nab-Paclitaxel and Gemcitabine, Abraxane®, Cytotoxic Antimicrotubular, Gemzar®, Pyrimidine Antimetabolite
PrECOG, LLC., Celgene Corporation
Cholangiocarcinoma
09/16
10/17
MispheC, NCT01912053: Efficacy Study of Intra-hepatic Administration of Therasphere® in Association With Intravenous Chemotherapy to Treat Cholangiocarcinoma

Completed
2
41
Europe
Therasphere® in association with Gemcitabine and Cisplatin, 90-Yttrium theraspheres
Center Eugene Marquis
Cholangiocarcinoma
12/16
11/17
NCT00059865: Gemcitabine Plus Pemetrexed Disodium in Treating Patients With Unresectable or Metastatic Biliary Tract or Gallbladder Cancer

Completed
1/2
68
US
gemcitabine hydrochloride, pemetrexed disodium
Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI)
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
02/07
02/08

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