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| Not yet recruiting | 1 | 10 | | | Medlab Clinical, Medlab Clinical | Anxiety | | | | |
ACTRN12618001135202: Comparative bioavailability assessment between 4 x 60 mg R107 tablets administered orally and 0.5mg/kg ketamine IV infusion over 40 minutes in healthy male and female participants under fasting conditions. |
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| Not yet recruiting | 1 | 12 | | | Zenith Technology Corporation Limited, Douglas Pharmaceuticals Limited | Depression, Anxiety | | | | |
ACTRN12622000446763: Comparative bioavailability assessment between 1 x 60 mg R-192 tablet and 1 x 60 mg R-107 tablet administered orally in healthy participants under fasting conditions. |
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| Not yet recruiting | 1 | 14 | | | Zenith Technology Corporation Limited, Douglas Pharmaceuticals Limited | Depression, Anxiety | | | | |
ACTRN12623000884606: Functional, cognitive and behavioural effects of 5-MeO-DMT administered by intramuscular injection |
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| Not yet recruiting | 1 | 15 | | | Swinburne University of Technology, Hawthorn, Psychedelic Research in Science & Medicine (PRISM) Ltd | Depression | | | | |
ACTRN12624000025538: A study to assess two formulations of VLS-01 (VLS-01-IV and VLS-01-BU) in Healthy Adult Volunteers |
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| Not yet recruiting | 1 | 16 | | | atai Therapeutics Pty. Ltd., atai Therapeutics Pty. Ltd. | Depression | | | | |
ACTRN12621000868886p: A Phase I Trial on The Bioavailability and Half-Life of Sublingually Administered Cannabis Products in Healthy People |
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| Not yet recruiting | 1 | 20 | | | Soma Group Limited, Soma Group Limited | Anxiety | | | | |
ACTRN12621000868886: A Phase I Trial on The Bioavailability and Half-Life of Sublingually Administered Cannabis Products in Healthy People |
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| Not yet recruiting | 1 | 20 | | | Soma Group Limited, Soma Group Limited | Anxiety | | | | |
ACTRN12623000832673: Treatment Resistant Depression Intervention with Psilocybin-assisted Psychotherapy |
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| Not yet recruiting | 1 | 20 | | | St. Vincent's Hospital, Sydney, Black Dog Institute | Treatment Resistant Depression | | | | |
ACTRN12617001339347p: Effects of lithium and fampridine on electroencephalography profiles in healthy volunteers |
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| Not yet recruiting | 1 | 24 | | | University of Otago, University of Otago | Bipolar Disorder | | | | |
ACTRN12620001102965p: Pharmacokinetics of allopregnanolone after multiple dose administration of progesterone in post-menopausal healthy volunteer women. |
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| Not yet recruiting | 1 | 24 | | | Royal Australian New Zealand College of Psychiatry, Royal Australian New Zealand College of Psychiatry | Post Partum Depression; Postnatal care. | | | | |
ACTRN12617001339347: Effects of lithium and fampridine on electroencephalography profiles in healthy volunteers |
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| Not yet recruiting | 1 | 24 | | | University of Otago, University of Otago | Bipolar Disorder | | | | |
ACTRN12620001102965: Pharmacokinetics of allopregnanolone after multiple dose administration of progesterone in post-menopausal healthy volunteer women. |
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| Not yet recruiting | 1 | 24 | | | Royal Australian New Zealand College of Psychiatry, Royal Australian New Zealand College of Psychiatry | Post Partum Depression, Postnatal care. | | | | |
ACTRN12616001351404: A single and multiple dose safety and tolerability study of oral ketamine in healthy volunteer and patients with a history of depression or anxiety. |
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| Not yet recruiting | 1 | 48 | | | Zenith Technology Corp Ltd, Douglas Pharmaceuticals Limited | Depression, Anxiety | | | | |
ACTRN12621000160831p: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GRX-917 in Healthy Subjects |
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| Not yet recruiting | 1 | 76 | | | Gaba Therapeutics Australia Pty Ltd a subsidiary of Gaba Therapeutics, Inc, Gaba Therapeutics Australia Pty Ltd a subsidiary of Gaba Therapeutics, Inc | Anxiety | | | | |
| Not yet recruiting | 1 | 80 | | | PharmaCann Pty Ltd, PharmaCann Pty Ltd | Anxiety | | | | |
| Not yet recruiting | 1 | 190 | | | University of Otago, Otago University | Anxiety | | | | |
| Not yet recruiting | 1 | 190 | | | University of Otago, Otago University | Anxiety | | | | |
ACTRN12606000111572: A randomised controlled trial of a letter intervention in primary care patients to improve depression and anxiety disorders |
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| Not yet recruiting | 1 | 200 | | | The Alfred Hospital, Beyondblue | DSM-IV Axis 1 Depressive and Anxiety Disorders | | | | |
ACTRN12606000422527: Vietnam Veterans - Real Partners in Health: Does self-management support improve your health? |
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| Not yet recruiting | 1 | 200 | | | Department of Veteran Affairs, Department of Veteran Affairs | Alcohol-related disorders in Vietnam Veterans, Post Traumatic Stress Disorder in Vietnam Veterans, Major Depression in Vietnam Veterans | | | | |
ACTRN12606000483550: Randomised controlled trial of a New Zealand developed screening questionnaire for depression compared with a gold standard |
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| Not yet recruiting | 1 | 5500 | | | Dr Felicity Goodyear-Smith, Health Research Council of New Zealand | Depression | | | | |
ACTRN12622001315707: An open label study to evaluate the safety, tolerability, and subjective effects of two dimethyltryptamine (DMT) and harmala alkaloid containing formulations in healthy volunteers |
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| Recruiting | 1 | 8 | | | St Vincent's Hospital, Melbourne, Psychae Therapeutics | Depression, Alcohol Use Disorder, Trauma | | | | |
| Recruiting | 1 | 100 | | | University of Auckland, Oakley Mental Health Research Foundation | Mild-to-moderate depression | | | | |
| Recruiting | 1 | 120 | | | Gold Coast Community Child Health, Queensland Department of Health | Depression and Interpersonal problems (loss & grief, interpersonal disputes, social isolation, role transitions). | | | | |
ACTRN12605000203651: A Controlled Breathing Course Promoting Social and Emotional Health for Vietnam Veterans with Chronic Posttraumatic Stress Disorder - A Randomized Controlled Trial |
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| Active, not recruiting | 1 | 30 | | | University of Queensland | Post-traumatic Stress Disorder | | | | |
ACTRN12611000270910: Acceptance and Commitment Therapy (ACT) to enhance stress resilience in police recruits: A randomized control trial |
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| Active, not recruiting | 1 | 160 | | | Australian National University, NSW Police Association and NSW Police Joint Grant | Depression, Anxiety Disorders, Substance Use Disorders | | | | |
| Recruiting | 1 | 20 | | | University of Sydney, Unfunded | Death anxiety | | | | |
ACTRN12622000851763: VLS-01-101: A study to assess Two formulations of VLS-01 (VLS-01 BU and VLS-01-IV) in healthy participants |
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| Recruiting | 1 | 48 | | | Viridia Life Sciences Australia Pty Ltd, Viridia Life Sciences Australia Pty Ltd | Treatment resistant Depression (TRD) | | | | |
ChiCTR-IPC-15006566: Repetitive Transcranial Magnetic Stimulation (rTMS) Improves Facial Affect Recognition in bipolar disorder and the mechanism |
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| Not yet recruiting | 1 | 40 | | Repetitive Transcranial Magnetic Stimulation ;sham Repetitive Transcranial Magnetic Stimulation | Pecking University Sixth Hospital; Pecking University Sixth Hospital, Natural Science Foundation of China (81401101) | bipolar disorder | | | | |
ChiCTR-TRC-12002640: A phase III clinical research on renzhujianwei granule in treating chronic atrophic gastritis (qi deficiency, blood stasis and hot depression syndrome) |
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| Completed | 1 | 510 | | Renzhujianwei granule ;simulated agent of Renzhujianwei granule ;Renzhujianwei granule+ simulated agent of Weifuchu ;Weifuchun tablet +simulated agent of Renzhujianwei granule | General Hospital of Shenyang Miliary Region; General Hospital of Shenyang Miliary Region, Nanjing Zhongshan Pharmaceutical CO.,LTD | chronic atrophic gastritis | | | | |
ChiCTR-TRC-09000484: The Standardize Study on Treatment of Obsessive Compulsive Disorder by Acupoint Stimulating. |
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| Completed | 1 | 360 | | acupoint stimulating with medication ;acupoint stimulating with placebo ;blank stimulating with medication | Tongde Hospital of Zhejiang Province; 中华人民共和国科技部, 国家中医药管理局, The Ministry of Science and Technology of China, State Administration of Traditional Chinese Medicine | Obsessive Compulsive Disorder | | | | |
ChiCTR-TRC-13002976: A brief integrated sleep-focused treatment for persistent sleep disturbances in residual depression: An assessor-blind, parallel group, randomized controlled study |
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| Recruiting | 1 | 80 | | Cognitive-behavioral therapy for insomnia (CBT-I) versus imagery rehearsal therapy (IRT) | Health and Health Services Research Fund; The Chinese University of Hong Kong, Health and Medical Research Fund (HMRF) | Insomnia and Nightmare | | | | |
ChiCTR-IPC-15005969: Neurophysiological and biochemical mechanism involve in the efficacy of cognitive-coping therapy for obessive-compulsive disorder |
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| Recruiting | 1 | 360 | | Pharmacoterapy plus cognitive-coping therapy ;Pharmacotherapy plus psychological support ;No intervention or cognitive-coping therapy | Xinxiang Medical University; Xinxiang Medical University, Xinxiang Medical University, National Ntural Scienc Foundation of China | Obsessive-compulsive disorder | | | | |
ChiCTR-TRC-13003220: Prognostic influence of antidepressant treatment for stable chronic obstructive pulmonary disease patients with depression |
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| Completed | 1 | 120 | | antidepressant treatment ;placebo | Department of Respiratory Medicine, Huai’an Second People's Hospital; Level of the institution：, hospital preparation | chronic obstructive pulmonary disease | | | | |
| Recruiting | 1 | 60 | | Behavior An aerobic exercise programme consists of jogging, fast walking and cycling, as adjunct treatment to treatment as usual for 12 weeks versus Treatment as usual in the psychiatric outpatient clinics; | Dr. CHEUNG Lap Kei, the principal investigator, who is a resident in the Department of Psychiatry, Tai Po Hospital; Tai Po Hospital, self support | Depression | | | | |
ChiCTR-IPC-15006159: The effectiveness of acupressure for the management of depressive symptoms and mental health problems in elderly people: a randomised controlled trial |
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| Not yet recruiting | 1 | 144 | | Acupressure versus Sham acupressure and standard care. Duration: 12 weeks | School of Nursing, The Hong Kong Polytechnic University; Kwai Chung Hospital, Angel S.P. Chan Lau Endowed Fund | Depression | | | | |
| Not yet recruiting | 1 | 80 | | Music is played 20 minutes before and during colonoscopy procedure ;Participants are received the usual care plus music interventions. The usual care consists of before the colonoscopy, patients are required to receive a bowel cleaning preparation in order to ensure that the bowel is clear for proper visualization. ;The day of the procedure, patient is admitted to the day surgical ward, history and vital signs are completed, the consent of colonoscopy is obtained, and an intravenous line is inserted into the patient. | KO Shuk Yee; Level of the institution：, Nethersole School of Nursing, CUHK | Anxiety, pain, sedative and analgesic medication requirements, heart rate, blood pressure, and procedure satisfaction | | | | |
ChiCTR-IIC-16007820: Smiley Activation Project - Community/Home-based Depression Treatment for the Elderly |
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| Not yet recruiting | 1 | 40 | | Problem solving treatment and behavioral activation versus Treatment as usual ;It is a community-based treatment program using methods of problem solving treatment and behavioral activation to reduce depression in older adults with minor depression or dysthymia. Problem-solving treatment is a brief, practical psychological treatment which helps participants to identify and solve problems. ;Behavioral activation is a behavioral treatment that primarily focuses on increasing rewarding activities, overcoming avoidance living patterns, and re-establishing healthy life routines through pleasant activity scheduling. Talk and behavioral psychotherapy ;There would be four to eight sessions over a period of no more than six months. About 1 hour per session, Session 1 to 3: weekly; 4 to 5: biweekly; 6 to 8: monthly | City University of Hong Kong; Hong Kong Family Welfare Society, The Hongkong and Shanghai Banking Corporation Limited through the Community Chest of Hong Kong | depression | | | | |
ChiCTR-TRC-08000276: A study for the Mechanism of the scalp acupuncture therapy of depression by using PET technology |
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| Completed | 1 | 98 | | Oral administration F1 Uoxetine; of the 48 patients, 6 patients received the PET test before and after the treatment. ;Receive head acupuncture treatment. Acupoints: MS5, MS1 and MS2. Of the 50 patients, 12 received the PET test before and after the treatment. | College of TCM, Southern Medical University, First Military Medical University; Chinese National Natural Science Fund Committee, National Natural Science Foundation of China | Depression | | | | |
ChiCTR-TRC-09000438: Treatment of Depression Using Sleep Electroencephalogram Modulated Repetitive Transcranial Magnetic Stimulation |
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| Completed | 1 | 164 | | sleesleep electroencephalogram-modulated repetitive transcranial magnetic stimulation ;conventional repetitive transcranial magnetic stimulation ;Sham repetitive transcranial magnetic stimulation | Affiliated Lianyungang Hospital, Medical College of Xuzhou; Personnel Office, Science and Technology Office, Jiangsu Province, Personnel Office, Science and Technology Office, Jiangsu Province | Depression | | | | |
NCT00320645: Impact of Pregnancy and the Postpartum Period on Women With Bipolar Disorder |
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| Recruiting | 1 | 200 | US | | National Institute of Mental Health (NIMH) | Bipolar Disorder | | | | |
ChiCTR-TRC-08000278: The clinical research for the optimal design of electro-acupuncture in the treatment of light or medium depression |
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| Completed | 1 | 162 | | Electronic acupuncture. The acupoints same as acupuncture group include Baihui, Yintang, Fengfu, Fengchi(two sides), Dazhui, Leiguan (two sides), Shanyingjiao (two sides). Two days one time, three times a week, total 6 weeks. ;Drug control. Giving Paroxetine Hydrochloride Tablets, 10 mg ont time a day at first two days of treatment; from the third day, 20 mg one a day for 6 weeks. ;We search the same acupuncture points and take the same operation in both acupuncture groups. The acupoints same as acupuncture group include Baihui, Yintang, Fengfu, Fengchi(two sides), Dazhui, Leiguan (two sides), Shanyingjiao (two sides). Two days one time, three times a week, total 6 weeks. | Southern Medical University; Ministry of Science and Technology, People's Republic of China, , 11.5 State Key Project | Depression | | | | |
| Completed | 1 | 24 | | 30 mg po. (reference), washout 14 days, 30 mg po(test) ;30 mg po.(test), washout 14 days, 30 mg po (reference) | West China Hospital, Sichuan University; Novartis（Bengal）Pharmaceutical Co., Ltd., Novartis（Bengal）Pharmaceutical Co., Ltd. | Depression | | | | |
| Completed | 1 | 80 | | Nil | Hong Kong Family Welfare Society; None, Community Chest | depression and anxiety | | | | |
| Completed | 1 | 480 | | Acupuncture points: Baihui, Yitang, Fengfu, Fengchi(bilateral), Dazhui, Neiguan(bilateral), Sanyinjiao(bilateral). ;Acupuncture points: Baihui, Yitang, Fengfu, Fengchi(bilateral), Dazhui, Neiguan(bilateral), Sanyinjiao(bilateral). ;We use paroxetine HCl (comparing drug) as the base therapy. The dosage is 10mg/d at the beginning two days, and 20mg/d from two days to the end | Beijing University of Chinese Medicine; The Ministry of Science and Technology of The P.R. China, The Ministry of Science and Technology of China | The depression | | | | |
ChiCTR-CCS-12002164: The cognitive dysfunction and the regional cerebral blood flow in patients with obsessive-compulsive disorder |
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| Completed | 1 | 46 | | NA | Department of Psychology, Third Affiliated Hospital, Sun Yat-sen University; Third Affiliated Hospital ，Sun Yat-sen University, Technology Project of the Guangdong | obsessive-compulsive disorder | | | | |
NCT00896090: Cortical Excitability and Inhibition in Children and Adolescents With Major Depressive Disorder |
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| Recruiting | 1 | | US | | University of Texas Southwestern Medical Center, National Alliance for Research on Schizophrenia and Depression | Depression | 06/11 | 12/11 | | |
ChiCTR-TRC-10001123: A Randomized Controlled Trial of combination of Cognitive-Behavioral Therapy (CBT) with Selective Serotonin Reuptake Inhibitors (SSRIs) Therapy for Obsessive-Compulsive Disorder (OCD) and Generalized Anxiety Disorder (GAD) |
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| Completed | 1 | 400 | | combination of 16 times of CBT and therapeutic dose of SSRIs ;therapeutic dose of SSRIs ;therapeutic dose of SSRIs ;combination of 12 times of CBT and therapeutic dose of SSRIs | Peking University Sixth Hospital; Ministry of Science and Technique, China, National Key Technology R&D Program in the 11th Five year Plan of China | Obsessive-Compulsive Disorder(OCD) and Generalized Anxiety Disorder(GAD) | | | | |
ChiCTR-OCH-12002332: The instant effects of auricular pressing on heart rate variability of the pre-exam anxiety students: The autonomic nerve regulation action of auricular pressing |
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| Completed | 1 | 60 | | ear points press ;ear points press | Southern Medical University and Department of Clinical Medicine, University of Bergen; Level of the institution：, Special Funding for Research provided by Southern Medical University and Clinical School of Norway Bergen University | pre-exam anxiety | | | | |
ChiCTR-ONRC-11001311: A fcMRI Study on the post-effect of Electro-Acupuncture at Yintang (EX-HN3) and Baihui Acupoint (DU20) |
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| Completed | 1 | 24 | | reveive electro-acupuncture at Yintang (EX-HN3) and Baihui (DU20) for 30 min. Before and after the needling, all the volunteers receive the resting cerebral functional magnetic resonance scan by the GE 3.0T NMR spectrometer ;reveive electro-acupuncture at Yintang (EX-HN3) and Baihui (DU20) for 30 min. Before and after the needling, all the volunteers receive the resting cerebral functional magnetic resonance scan by the GE 3.0T NMR spectrometer | Southern Medical University; Southern Medical University, the 3rd Key Subject of the | primary depression | | | | |
| Completed | 1 | 16 | | a single oral dose of 25mg agomelatine | the Third Xiangya Hospital of Central South University; the Third Xiangya Hospital of Central South University, This work was supported by the National Scientific Foundation of China (No. 81373476, 81302851, 81301924) | depression | | | | |
ChiCTR-TRC-10000795: Oxygen therapy for memory dysfunction after electroconvulsive treatment: a randomized controlled trial |
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| Completed | 1 | 60 | | Patients were treated with cytidine diphosphate choline after ECT ;Patients were treated with oxygen therapy after ECT | Suzhou Guang-Ji Hospital; Level of the institution：, Self-funding | Major depression | | | | |
| Completed | 1 | 140 | | Add the following treatment based on the basic treatment: do the acupuncture on Lieque and Zhaohai, retain them for 30 mins after the needling sensation is attained; bury the intradermal needle after the withdrawal. Use 2 groups of acupoints: 1. Xinshu, Shenshu; 2. Danshu, Anmian, both groups are used alternately. ;Basic treatment, use the Siguan, Baihui and Yintang for acupuncture, after the needling sensation attained, manipulate the needle by the way of transporting qi. First the Four gates, and then Baihui, Yintang, after that, take a deep breath for 6 times, rest for 1 min and take deep breath again for&# | The second affiliated hospital of Guangzhou University of Chinese Medicine; Level of the institution：, Department of Science and Technology of Guangdong Province | insomnia with depression | | | | |
ChiCTR-TRC-11001540: An Investigation on the prioritization scheme in the treatment of Mild-to-moderate depressive Disorder by Acupuncture: A Randomized Controlled Clinical Trail |
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| Recruiting | 1 | 432 | | The patients receive a 30-minute electro-acupuncture treatment, applied once another day, total 3 times a week over 6 consecutive weeks. Meanwhile, Seroxat is administered as a dose of 10mg a day for the fist 2days, then increased to 20mg day. ;The patients receive a 30-minute manual acupuncture treatment, applied once another day, total 3 times a week over 6 consecutive weeks. ;The patients receive a 30-minute electro-acupuncture treatment, applied once another day, total 3 times a week over 6 consecutive weeks. ;The patients receive a 30-minute electro-acupuncture treatment, applied once another day, total 3 times a week over 6 consecutive weeks. ;Seroxat is administered as a dose of 10mg a day for the fist 2days, then increased to 20mg day, the total treatment is over 6 consecutive weeks. ;The patients receive a 30-minute manual acupuncture treatment, applied once another day, total 3 times a week over 6 consecutive weeks. Meanwhile, Seroxat is administered as a dose of 10mg a day for the fist 2days, then increased to 20mg day. | School of TCM, Southern Medical University; School of TCM, Southern Medical University, the 3rd Key Subject of the 211 Project of Guangdong Province | Mild-to-moderate depressive Disorder | | | | |
ChiCTR-TRC-13003179: The different effects of agomelatine and escitalopram on the circadian rhythmic system in the first episode depressive patients |
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| Completed | 1 | 90 | | agomelatine 25-50mg per day before sleep ;escitalopram 10-20mg per day after breakfast ;No intervention | National Institute on Drug Dependence, Peking University; Level of the institution：, Natural Science Foundation of China | Depression | | | | |
ChiCTR-OCC-12002329: A Functional Resting-state Magnetic Resonance Study on the Patients with Anxiety Disorder and Syndrome of Liver Depression Transforming into Fire |
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| Completed | 1 | 60 | | NA ;NA ;NA | The Second Affiliated Hospital of Beijing University of Traditional Chinese Medicine East Hospital encephalopathy two branch; The Second Affiliated Hospital of Beijing University of Traditional Chinese Medicine East Hospital, The doctoral program of higher education of specialized research fund | Anxiety disorder | | | | |
ChiCTR-TRC-12002738: The study on manual-based group cognitive-behavioral therapy for minor depressive disorder and dysthymia in Chinese population |
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| Completed | 1 | 200 | | mannual-based cognitive behavioral therapy ;Antidepressant drug | Shanghai Mental Health Center; None, Algorithm Guided Treatment Strategies for Major Mental Disorders | minor depressive disorder and dysthymia | | | | |
| Completed | 1 | 80 | | Acupuncture ;Acupuncture | Nanjing Brain Hospital; None, the Foundation of traditional Chinese Medicine Department of Jiangsu Health | Depression | | | | |
ChiCTR-TRC-12003489: Early intervention and prevention with acupuncture therapy on the post stroke depression: A randomized controlled clinical trial |
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| Completed | 1 | 244 | | Acupuncture ;NA | Jiangsu Province Hospital of Traditional Chinese Medicine; Jiangsu Province Hospital of Traditional Chinese Medicine, State Administration of Traditional Chinese Medicine | post stroke depression | | | | |
Medlink, NCT01583764: Mobile Technology to Engage and Link Patients and Providers in Antidepressant Treatment |
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| Not yet recruiting | 1 | 50 | US | Medlink system | Northwestern University, National Institute of Mental Health (NIMH) | Depressive Disorder, Major | 01/15 | 04/15 | | |
2005-005645-19: RCT of oral ibuprofen for procedural anxiety, distress and pain in children with cancer |
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| Ongoing | 1 | 50 | Europe | ibuprofen, | Dept of ped hem/onc | Pain and anxiety relief before needle insertion in a subcutanously implanted iv port in children with cancer. | | | | |
ChiCTR-IPR-15006300: The Impact Of Music Combined Taichi Exercise Therapy On Depression Among Community-dwelling Elderly |
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| Recruiting | 1 | 118 | | music combined with Taichi exercise ;Control | Yaan Vocational College; None, Self-collected | Geriatric depression | | | | |
ChiCTR-OCC-14004280: Study for the funtion and mechanism of MicroRNAs in the patients with depression and antidepression treatment by ketamine |
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| Completed | 1 | 60 | | Nil | Affiliated Hospital of Luzhou Medical College; Affiliated Hospital of Luzhou Medical College, the National Natural Science Foundation of China | Depression | | | | |
ChiCTR-IPC-15006700: Efficacy and immune mechanisms of omega-3 as synergist in treatment of major depressive disorder |
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| Not yet recruiting | 1 | 80 | | Antidepressants + Omega-3 ;Antidepressants | Guangzhou Huiai Hospital; Guangzhou Huiai Hospital, Guangzhou key medical disciplines (GBH2014-ZD08) | Major depressive disorder | | | | |
ChiCTR-IPR-15005911: Establishment and intervention block mechanism of a "profession - management - autonomy" positive psychological experience intervention model among empty nesters |
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| Not yet recruiting | 1 | 200 | | profession - management - autonomy intervention model ;regular health promotion intervention. | Wenzhou Medical University; Level of the institution：, the Natural Science Project of Zhejiang province (LY14G030025) and self-raised funds | empty nester depression anxiety | | | | |
ChiCTR-OIC-17011465: A Controlled Study of Effect of Intervention in Strengthening Outpatient with Bipolar Disorder and the Development and Evaluation of Tools |
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| Completed | 1 | 80 | | manual-based group cognitive-behavioral therapy | Shanghai Mental Health Center; Shanghai Mental Health Center, Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University | Bipolar Disorder | | | | |
ChiCTR-IPQ-15006310: Relationship between postpartum depression and labor pain:the neurobiology mechanism |
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| Recruiting | 1 | 616 | | TENS+Dola ;Dola ;ANALGESIA+DOLA | Women's Hospital, School of Medicine, Zhejiang University; Women's Hospital, School of Medicine, Zhejiang University, National Natural Science Foundation 81371244 | Postpartum depression | | | | |
ChiCTR1800018699: Bioequivalence evaluation of two paroxetine tablets before and after meals in healthy Chinese volunteers: A Single-dose, randomized, open-label, two-period crossover trial |
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| Not yet recruiting | 1 | 56 | | test drug in the 1st period and reference drug in the 2nd period ;reference drug in the 1st period and test drug in the 2nd period | The First Affiliated Hospital, Zhejiang University; Jianfeng Pharmaceuticals, All funds provided by the project sponsor Zhejiang Jianfeng Pharmaceutical Co., Ltd. | Depression | | | | |
ChiCTR1800018430: Study on brain structural MRI in post traumatic stress disorder patients who lost child |
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| Not yet recruiting | 1 | 40 | | Functional magnetic resonance examination ;Functional magnetic resonance examination | First Affiliated Hospital of Medical College, Shihezi University; Level of the institution：, 2012 Corps Science and Technology Key Areas | Post-traumatic stress disorder | | | | |
ChiCTR-IIR-17010453: The correlation of SCIT intervention and brain network connection in patient with major depressive disorder |
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| Recruiting | 1 | 240 | | no ;SCIT intervention ;CBT Intervention | Tianjin Anding Hospital (Tianjin Mental Health Centre); Tianjin Anding Hospital (Tianjin Mental Health Centre), The Key Research Project of Tianjin Health Bureau | major depressive disorder | | | | |
| Not yet recruiting | 1 | 176 | | dancing program ;usual care | no sponsor; Level of the institution：, No funding | breast cancer | | | | |
ChiCTR1800016589: Effects of immersive virtual reality intervention on pain and anxiety among pediatric patients undergoing venipuncture: A randomized controlled trial |
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| Not yet recruiting | 1 | 200 | | Immersive virtual reality ;receive standard care only | The Nethersole School of Nursing, The Chinese University of Hong Kong; Nil, Nil | Pain | | | | |
ACTRN12620000571976: Evaluation of Shift, a smartphone application for Junior Medical Officers in New South Wales during the COVID-19 epidemic. |
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| Active, not recruiting | 1 | 75 | | | UNSW Sydney (University of New South Wales, Sydney), NSW Ministry of Health, Insurance and Care NSW, Australian Government Department of Health | Depression, Anxiety, COVID-19-related anxiety | | | | |
| Recruiting | 1 | 120 | | Intervention 3.2g/day, oral, three months ;placebo 3.2g/day, oral, three months | Tianjin Medical University; Tianjin Medical University, BY-HEALTH Co., Ltd. | depression | | | | |
ChiCTR1900026481: Bioequivalence pre-test of fluoxetine hydrobromide in healthy humans |
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| Not yet recruiting | 1 | 24 | | T ;R ;T ;R | Changsha Third Hospital; Changsha Third Hospital, Offer by the sponsor | Adult depression | | | | |
iCBT for GAD, ChiCTR2000032618: Treatment of generalized anxiety disorder: A randomized controlled trial of an internet self-help program with minimal non-therapist support |
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| Not yet recruiting | 1 | 114 | | internet self-help program ;waitlist, to receive same internet self-help program 10 weeks after subject recruitment | Nil, student study; Level of the institution：, Nil, student study | Generalized Anxiety Disorder | | | | |
NCT04536233: Effects of MSCs Derived Pleiotropic Factors on Wound Healing in Endonasal Surgeries |
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| Not yet recruiting | 1 | 50 | NA | MSCs Derived Pleiotropic Factors, physiological saline | Chinese PLA General Hospital | MSCs Derived Pleiotropic Factors on Wound Healing in Endonasal Surgeries | 01/21 | 03/21 | | |
2021-000567-77: A study to evaluate the safety and tolerability and to assess blood levels of seltorexant in adolescents with Major Depressive Disorder who have not responded well to their current antidepressant and psychotherapy |
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| Ongoing | 1 | 52 | Europe, US | Seltorexant 20mg Film Coated tablets, Seltorexant 10mg Film coated tablets, JNJ-42847922, Film-coated tablet | Janssen-Cilag International NV, Janssen-Cilag International NV | Major Depressive Disorder, Depression, Diseases [C] - Nervous System Diseases [C10] | | | | |
NCT04658732: A Comparative Study of Oral Gabapentin, Oral Alprazolam and Intravenous Dexmedetomidine on Perioperative Anxiety and Pain During Posterior Segment Eye Surgery Under Peribulbar Block : a Randomized, Double-blind Study. |
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| Recruiting | 1 | 45 | RoW | Administration of Alprazolam , Gabapentin , Dexmedetomidine | Ehab Tarek Fahmy | Sedation for Patients Undergoing Peribulbar Block | 06/21 | 08/21 | | |
| Not yet recruiting | 1 | 106 | | Brief psychoeducation ;Digital intervention | Research Services and Knowledge Transfer Office (RSKTO), University of Macau; Macao Foundation, University of Macau | depression | | | | |
| Not yet recruiting | 1 | 30 | NA | Duavive 0.45Mg-20Mg Tablet, Duavive | St. Joseph's Healthcare Hamilton, McMaster University, Pfizer | Menopause, Depression, Anxiety, Sleep | 09/21 | 09/21 | | |
ChiCTR2100049759: Effects of Electroacupuncture Combined with Psychological Intervention on Hospitalized Patients with Post-Stroke Depression |
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| Not yet recruiting | 1 | 100 | | Electroacupuncture ;No | Qilu Hospital of Shandong University; Qilu Hospital of Shandong University, self-funded | Post-Stroke Depression | | | | |
2021-001337-40: STUDY TO DETERMINE EFFICACY AND SAFETY OF BXCL501 IN AGITATION ASSOCIATED WITH PEDIATRIC SCHIZOPHRENIA AND BIPOLAR DISORDER ESTUDIO PARA DETERMINAR LA EFICACIA Y LA SEGURIDAD DE BXCL501 EN LA AGITACIÓN ASOCIADA A ESQUIZOFRENIA Y TRASTORNO BIPOLAR PEDIÁTRICOS |
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| Not yet recruiting | 1 | 120 | Europe | BXCL501, Buccal film | BioXcel Therapeutics, Inc., BioXcel Therapeutics, Inc. | Subject that meets DSM-5 criteria for schizophrenia, schizoaffective, or schizophreniform disorder, or other specified/unspecified schizophrenia spectrum and/or other psychotic disorders OR Subject meets DSM-5 criteria for bipolar disorder (bipolar I or II ). Pacientes que cumplan los criterios de DSM-5 para esquizofrenia, trastorno esquizoafectivo o trastorno esquizofreniforme u otro espectro de esquizofrenia especificado/no especificado uy otros trastornos psicóticos O Pacientes que cumplan los criterios de DSM-5 para trastorno bipolar (bipolar I o II)., Schizophrenia and bipolar disorder Esquizofrenia y trastorno bipolar, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT03953729: Effectiveness of Pre-emptive Analgesia in Children With Molar-incisor Hypomineralization (MIH) |
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| Recruiting | 1 | 50 | RoW | Ibuprofen, Placebo | University of Sao Paulo | Pain, Anxiety | 10/21 | 12/21 | | |
| Recruiting | 1 | 112 | | single dose ;20/40/80mg,oral every day, 7days ;High fat diet | Chinese PLA General Hospital; Level of the institution：, Sponsor | Major depressive disorder | | | | |
NCT04097080: Comparative Controlled Study of Analgesic, Antiasthenic and Anti-Anxiety Effects of Xenon in Patients With Parkinson's Disease |
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| Recruiting | 1 | 60 | RoW | NBTX-001, Standard of Care | Nobilis Therapeutics Inc. | Parkinson Disease | 11/21 | 12/21 | | |
NCT04729244: The Study of Hemp Oil CBD for Evaluation of Efficacy and Safety in Treatment of Pain, Anxiety and Insomnia Management |
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| Not yet recruiting | 1 | 30 | US | CBD, CBD tincture, CBD cream | Advanced Pain and Rehab Specialists, Hemp synergistics | CBD, Pain, Chronic, Anxiety, Insomnia, Opioid Use | 11/21 | 02/22 | | |
NCT04939909: Botulinum Toxin Relieves Anxiety, Depression and Sleep Disorderes in Patients With Blepharospasm |
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| Recruiting | 1 | 50 | RoW | Botulinum toxin type A | Second Affiliated Hospital, School of Medicine, Zhejiang University | Blepharospasm | 12/21 | 07/22 | | |
ChiCTR2100052595: A Single-Center, Open-Label, Randomized, Single-Dose, Two-Period, Two-Sequence, Crossover Study to Assess the Bioequivalence of Test Formulation Amitriptyline Hydrochloride Tablets with Reference Formulation Amitriptyline Hydrochloride Tablets in Healthy Adult Subjects under Fasting and Fed Conditions |
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| Recruiting | 1 | 50 | | TR ;RT | The First Affiliated Hospital of Zhejiang University School of Medicine; Changzhou SiYao pharmaceutical co., LTD, All funds provided by the project sponsor Changzhou SiYao pharmaceutical Co., Ltd. | depression | | | | |
ChiCTR2000040759: Association between anxiety and clinical outcomes in patients with hypertrophic cardiomyopathy |
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| Not yet recruiting | 1 | 600 | | None | Jiaxing Science and Technology Bureau; The First Hospital of Jiaxing, Jiaxing Science and Technology Bureau | Hypertrophic cardiomyopathy | | | | |
ACTRN12621001365853: A study of RLS103 (CBD-Technosphere® Inhalation Powder) in Healthy Adult Volunteers
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| Completed | 1 | 30 | | | Receptor Life Sciences Australia Pty Ltd, Receptor Life Sciences Australia Pty Ltd | Panic Disorder , Social Anxiety Disorder | | | | |
| Completed | 1 | 10 | US | WET | University of Texas at Austin, University of Michigan | Posttraumatic Stress Disorder, Depressive Symptoms, Burn Out, Anxiety, Work Related Stress | 03/23 | 09/23 | | |
NCT05912335: Clinical Efficiency of Xanthan Hydrogels Containing Local Anesthetics Encapsulated in Nanostructured Lipid Carries |
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| Completed | 1 | 40 | RoW | Topical anesthetic, Topical Formulation | University of Campinas, Brazil | Dental Trauma, Local Anesthesia, Oral Cavity Disease | 02/22 | 05/22 | | |
| Completed | 1 | 61 | US | Radically Open Dialectical Behavior Therapy (RO DBT) | Washington University School of Medicine | Anorexia Nervosa, Obsessive-Compulsive Disorder, Social Phobia, Depression, Anxiety | 02/22 | 02/22 | | |
ACTRN12621000436875: A randomised, double-blind, placebo-controlled trial of repeated microdoses of lysergic acid diethylamide (LSD) in healthy volunteers |
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| Completed | 1 | 80 | | | The University of Auckland, Health Research Council of New Zealand | Major depressive disorder | | | | |
NCT04922593: Relative Bioavailability of LY03010 Compared to Listed Drug |
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| Completed | 1 | 281 | US | LY03010; paliperidone palmitate, INVEGA SUSTENNA | Luye Pharma Group Ltd. | Schizophrenia, Psychotic Disorders, Mood Disorders, Schizophrenia Spectrum, Mental Disorders, Antipsychotic Agents, Tranquilizing Agents, Central Nervous System Depressants, Physiological Effects of Drugs, Psychotropic Drugs, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action | 03/22 | 04/22 | | |
ChiCTR2100051813: Aerobic exercise improves anxiety, depression and cognitive flexibility under stress |
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| Not yet recruiting | 1 | 45 | | Aerobic bicycle ;None | Guangzhou Sport University; Guangzhou Sport Universiry, None | N/A | | | | |
NCT05015192: Single Ascending Dose Study of NH102 in Healthy Subjects |
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| Recruiting | 1 | 72 | RoW | NH102, H04, Placebo | Jiangsu Nhwa Pharmaceutical Co., Ltd. | Depression | 04/22 | 04/22 | | |
NCT04280965: Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury |
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| Completed | 1 | 28 | US | Quetiapine Fumarate, Seroquel, Standard of care meducations | The University of Texas Health Science Center at San Antonio, South Central MIRECC | Post Traumatic Stress Disorder | 04/22 | 10/22 | | |
ChiCTR2100047195: The effectiveness evaluaton of Intervention model of perinatal depression in women with fetal anomaly |
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| Recruiting | 1 | 52 | | Perinatal depression intervention program ;Routine nursing | Third Xiangya Hospital of Central South University; Central South University, National Natural Science Foundation of China (General Project) | depression | | | | |
NCT05196971: A Study To Evaluate The Safety, Tolerability And Pharmacokinetics of HS-10345 In Treatment-Resistant Depression |
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| Completed | 1 | 12 | RoW | HS-10345 84mg, HS-10345, Placebo, HS-10345 Placebo | Jiangsu Hansoh Pharmaceutical Co., Ltd. | Treatment Resistant Depressive Disorder | 04/22 | 10/22 | | |
