| Metabolic Diseases |
NCT00942552: Treatment of Mild Gestational Diabetes With Glyburide Compared to Placebo |
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| Recruiting | 4 | 400 | US | Glyburide, Placebo, ADA diet + nutritional counseling | University of Texas Southwestern Medical Center | Gestational Diabetes, Pregnancy Complications | 06/10 | | | |
NCT01865214: Outcome and Treatment Quality Study of Tolvaptan to Treat Hyponatremia in Patients With Heart Failure. |
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| Recruiting | 4 | 100 | RoW | Tolvaptan | Korea Otsuka International Asia Arab, Korea Otsuka Pharmaceutical Co.,Ltd. | Heart Failure With Hyponatremia | 07/14 | 12/14 | | |
NCT01816997: The Statins on Glucose Homeostasis in Subjects With Impaired Fasting Glucose |
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| Recruiting | 4 | 160 | RoW | Pravastatin, Pravastatin (Mevalotin), Rosuvastatin, Crestor, Control, placebo | Taipei Veterans General Hospital, Taiwan | Diabetes | 12/17 | 12/22 | | |
NCT00923715: Exenatide (Byetta) Versus Pramlintide (Symlin): Role in Post-Prandial Hyperglycemia |
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| Enrolling by invitation | 3 | 63 | US | Insulin, Insulin and Exenatide, Insulin and Pramlintide | Baylor College of Medicine, Albert Einstein College of Medicine of Yeshiva University | Diabetes Mellitus, Type 1 | 12/11 | 05/12 | | |
| Not yet recruiting | 3 | 300 | US | Vitamin D3 Supplementation | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type 2 Diabetes | 12/17 | 12/17 | | |
| | 2 | 24 | US | Glutamine, Glutamine Dipeptide, Placebo, Surgery | Ziegler, Thomas R., M.D. | Stress Hyperglycemia, Insulin Resistance, Trauma, Critical Illness | 07/13 | 02/14 | | |
NCT00005130: Coronary Artery Risk Development in Young Adults |
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| Active, not recruiting | N/A | 5115 | NA | | National Heart, Lung, and Blood Institute (NHLBI) | Cardiovascular Diseases, Coronary Disease, Hypertension, Heart Diseases, Obesity, Diabetes Mellitus | 06/33 | 06/33 | | |
NCT00934258: Effect of Genes on Rosuvastatin Therapy for Hyperlipidemia |
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| Available | N/A | | RoW | rosuvastatin,fenofibrate, CYP2C9, UGT1A1, UGT1A3, OATP2, BCRP | National Taiwan University Hospital | Hyperlipidemia | | | | |
NCT00965315: A Multicenter Randomized Parallel-group Study to Investigate the Efficacy of a Combination of Rosuvastatin and Fenofibrate in the Patients With Diabetes or Atherosclerotic Vascular Diseases With Metabolic Syndrome |
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| Available | N/A | | RoW | Rosuvastatin,SFC fenofibrate | National Taiwan University Hospital | Diabetes, CVD | | | | |
NCT00948493: Treatment Use of Generex Oral-lyn™ in Patients With Diabetes |
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| No Longer Available | N/A | | US | Buccal insulin spray, Generex Oral-lynTM (oral, buccal insulin spray) | Generex Biotechnology Corp. | Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus | | | | |
NCT01049633: B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure |
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| No Longer Available | N/A | | US | Allogeneic Pancreatic Islet Cells, Sirolimus, Basiliximab, Tacrolimus, Antibacterial, Antifungal, and Antiviral Prophylaxis, Trimethoprim/sulfamethoxazole, Septra SS, Clotrimazole, Mycelex Troche, Valganciclovir, Valcyte, Heparin, Anticoagulation and Hematological Agent, Enoxaparin, Lovenox; Anticoagulation and Hematological Agent, Pentoxifylline, Aspirin, ASA | National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type 1 Diabetes Mellitus | | | | |
NCT02300753: Emergency Administration of EPI-743 to a Single Patient With Leber's Hereditary Optic Neuropathy [LHON] |
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| No Longer Available | N/A | | US | EPI-743, Vincerinone (TM), Vatiquinone | Edison Pharmaceuticals Inc | Leber's Hereditary Optic Neuropathy | | | | |
| Available | N/A | | RoW | Abroma Augusta Q (mother tincture), Abroma Augustum, | Fr Muller Homoeopathic Medical College | Type II Diabetes Mellitus | 12/14 | 12/14 | | |
NCT01798914: Patient Transitioning From Exubera® Inhalation Powder to Technosphere® Insulin Inhalation Powder |
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| No Longer Available | N/A | | US | Technosphere Insulin Inhalation Powder, Afrezza Inhalation Powder | Mannkind Corporation | Type 1 Diabetes, Type 2 Diabetes | 04/15 | 05/15 | | |
NCT02008188: Early Feasibility Study of Adaptive Advisory/Automated (AAA) Control of Type 1 Diabetes (Italy) |
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| Active, not recruiting | N/A | 12 | Europe | Closed Loop Control with the Advisory/Automated Adaptive (AAA) Control system | University of Virginia, National Institutes of Health (NIH) | Type 1 Diabetes Mellitus | 05/15 | 05/15 | | |
NCT01309022: Immunosuppressive Medications for Participants in ITN005CT (NCT00014911) |
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| No Longer Available | N/A | | US | Sirolimus, Rapamune®, Tacrolimus, Prograf®, Mycophenolate mofetil, MMF, CellCept, Mycophenolic acid, Myfortic® | National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN) | Diabetes Mellitus, Type 1 | | | | |
| | N/A | 120 | US | Exercise training protocol, cardio, resistance training, Dietary, diet, nutrition, Educational control., education, behavioral | University of Pittsburgh, National Institute on Aging (NIA) | Aging | 09/16 | 09/16 | | |
NCT02097251: An Open-Label Treatment Protocol With UX003 rhGUS Enzyme Replacement Therapy for an Advanced Stage MPS 7 Patient |
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| No Longer Available | N/A | | US | UX003, recombinant human beta glucuronidase, rhGUS | Joyce Fox, Ultragenyx Pharmaceutical Inc | Mucopolysaccharidosis Type 7 | | | | |
CLA, NCT01797276: Dichloroacetate Treatment of Congenital Lactic Acidosis Phase B: Expanded Access |
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| No Longer Available | N/A | | US | Dichloroacetate, DCA | University of Florida | Mitochondrial Enzyme Deficiencies | | | | |
NCT01883154: The Impact of Placental Factors on Fetal Intrauterine Growth and in Intrauterine Programming of the Metabolic Syndrome |
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| Not yet recruiting | N/A | 160 | RoW | | Meir Medical Center | Normal Pregnancies | 09/17 | 09/23 | | |
NCT02233257: Expanded Access for Lorenzo's Oil (GTO/GTE) in Adrenoleukodystrophy |
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| No Longer Available | N/A | | US | Lorenzo's Oil, Glyceryl trierucate | University of Minnesota | X-linked Adrenoleukodystrophy | | | | |
NCT00962260: Expanded Access Trial of Plant Expressed Recombinant Glucocerebrosidase (prGCD) in Patients With Gaucher Disease |
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| No Longer Available | N/A | | US, RoW | Plant cell expressed recombinant glucocerebrosidase (prGCD), taliglucerase alfa | Pfizer | Gaucher Disease | | | | |
| Enrolling by invitation | N/A | 80 | Europe | | Oslo University Hospital, Aarhus University Hospital | Diabetes Mellitus, Pancreas Transplantation, Allograft Rejection, Surgical Complication Nec, Allograft Biopsies | 04/19 | 10/28 | | |
NCT02035891: Low-dose Colchicine in Patients With Type 2 Diabetes Mellitus and Microalbuminuria |
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| Active, not recruiting | N/A | 160 | RoW | colchicine 0.5mg/d, placebo 0.5mg/d | Chongqing Medical University | Diabetic Nephropathy | 09/19 | 06/23 | | |
| Recruiting | N/A | 750 | US | | Cystinosis Research Foundation | Cystinosis, Nephropathic Cystinosis, Renal Fanconi Syndrome | 12/20 | 12/22 | | |
| Active, not recruiting | N/A | 366 | Europe | Pre-diabetes screening | Nantes University Hospital | Pre-diabetes | 06/23 | 06/23 | | |
NCT02003781: Individualized Prevention Strategy for High Risk Patients in Cardiovascular Disease: Prospective Cohort Study (Cardiovascular and Metabolic Disease Etiology Research Center - HIgh Risk Cohort) CMERC-HI |
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| Recruiting | N/A | 4000 | RoW | | Yonsei University | High Risk Cardiovascular Disease Patients | 10/23 | 10/23 | | |
NCT01055093: Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients |
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| Recruiting | N/A | 2000 | Europe | | German Diabetes Center | Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2 | 09/25 | 09/35 | | |
| Enrolling by invitation | N/A | 2246 | Europe | Individual treatment, mulitinterventional | Odense University Hospital, Region of Southern Denmark, Hospital of South West Denmark, General Practice Research Database | Type 2 Diabetes, Hypertension | 10/25 | 10/25 | | |
| Recruiting | N/A | 2000 | Europe | Fibrosis Biomarkers, AST:ALT ratio, APRI, BARD score, ELF Score, FIB4, NAFLD Fibrosis Score,Transient Elastography | University of Nottingham | Chronic Liver Disease, Alcohol Use Disorder, Type 2 Diabetes, Persistently Elevated ALT, Obesity | 05/33 | 05/33 | | |
NCT01386801: Multicenter Research Study to Build a Repository to Study Chronic Diseases in Indiana |
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| Active, not recruiting | N/A | 1000 | US | | Fairbanks Institute, Indiana University School of Medicine, Richard M. Fairbanks Foundation, BioCrossroads, Regenstrief Institute, Inc. | Diabetes Mellitus Type II | 12/49 | 06/50 | | |
NCT01779115: Registry of Diabetes Patients in a Large Health Maintenance Organization in Israel |
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| Enrolling by invitation | N/A | 126000 | RoW | | Maccabi Healthcare Services, Israel | Type 1 Diabetes, Type 2 Diabetes | 12/00 | | | |