| Mental Retardation |
2006-004891-10: Future strategies for vocational rehabilitation schizophrenia |
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| Ongoing | 4 | 100 | Europe | Ziprasidon, Risperidon, Capsule, hard, Film-coated tablet, Zeldox Hartkapseln, Risperdal | Charité - Universitätsmedizin Berlin | The social implications and long-term consequences of mental disorders regarding sick days at work, unemployment rates and early retirement are considerable. This trial is being conducted to understand whether and how atypical antipsychotic treatment effects long-term job rehabilitation in daily life and 2) and whether, how and which social psychiatric strategies (job consulting, vocational services, work rehabilitation, individual cognitive training) support or amplify these beneficial effects. | | | | |
2010-024551-82: This a study using Atomoxetine in children with Attention Deficit Hyperactivity Disorder (ADHD) and a specific deletion in the 22qDS gene. |
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| Ongoing | 4 | 40 | Europe | Strattera 10mg, Strattera 18mg, Straterra 25mg, Straterra 40mg, Straterra 60mg, Straterra 80mg, Capsule, hard, Strattera 10mg, Strattera 18mg, Strattera 25mg, Strattera 40mg, Strattera 60mg, Strattera 80mg | King's College London, South London and Maudsley NHS Foundation Trust, King's College London, NIHR Central Commissioning Facility | Attention Deficit Hyperactivity Disorder (ADHD) in children with 22qDS deletion syndrome, Attention Deficit Hyperactivity Disorder (ADHD) in children with 22qDS deletion syndrome, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2011-005476-41: Ketamine augmentation of (meaning addition to) ECT to improve outcomes in depression. |
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| Ongoing | 4 | 180 | Europe | Ketalar, Solution for injection/infusion, Ketalar | Manchester Mental Health and Social Care Trust, Efficacy and Mechanism Evaluation programme, National Health Service | Depressive disorder requiring treatment with electroconvulsive treatment (ECT), Depression requiring treatment with electroconvulsive treatment (ECT), Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2012-000547-27: A Pilot Randomised Controlled Trial of Drug Treatment for Depression in Patients undergoing Haemodialysis |
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| Ongoing | 4 | 60 | Europe | Sertraline, Capsule, Sertralin - 1 A Pharma® 50 mg Filmtabletten | East and North Hertfordshire NHS Trust, University of Hertfordshire, National Institute of Health Research, | Major Depressive Disorder in Patients with End Stage Renal Disease, Depression in patients with kidney disease, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2012-003072-39: Oxytocin in PTSD: Effectiveness in addition to psychotherapy Oxytocine bij PTSS: Effectiviteit als toevoeging aan psychotherapie |
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| Ongoing | 4 | 24 | Europe | Nasal drops, solution, Syntocinon, nasal spray 40 IU/ml | Academic Medical Center, University of Amsterdam, Academic Medical Center, University of Amsterdam | Posttraumatic stress disorder Posttraumatische stress stoornis, posttraumatic stress disorder posttraumatische stress stoornis, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2012-001548-23: Doxazosin for PTSD With sleepregistration (DoPS). Doxazosine voor PTSS met slaapregistratie (DoPS) |
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| Ongoing | 4 | 20 | Europe | Doxazosin, Capsule | ParnassiaBavoGroup, ParnassiaBavoGroup | Posttraumatic stress disorder posttraumatische stress stoornis, Posttraumatic Stress disorder. posttraumatische stress stoornis, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Ongoing | 4 | 165 | Europe | escitalopram or nortriptyline, Capsule, Escitalopram 5mg (RVG 30494) Nortriptyline 10mg (RVG 03285) and 25mg (RVG 03286) | University Medical Center Groningen, ZonMW, Lundbeck BV | Major Depressive Disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Ongoing | 4 | 60 | Europe | Sertraline, Generic sertraline, Tablet, Sertraline | Hertfordshire Partnership University NHS Foundation Trust, University of Hertfordshire, National Institute of Health Research, Hertfordshire Partnership University Foundation NHS Trust, South West London and St Georges Mental Health NHS Trust, Southern Health NHS Foundation Trust | Obsessive Compulsive Disorder, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2010-021343-41: Variations of blood phenylalanine and tyrosine in children with phenylketonuria under sapropterin |
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| Ongoing | 4 | 20 | Europe | Soluble tablet, Kuvan | University Medical Center Groningen, Merck KGaA | Phenylketonuria (PKU) is an autosomal recessive metabolic genetic disorder by a mutation in the gene for the enzyme phenylalanine hydroxylase (PAH), rendering it nonfunctional. Left untreated, the disease will result in high concentrations of phenylalanine (Phe) in blood and tissues, likely resulting in severe mental retardation and behavioural problems. Treatment focusus on the restriction of dietary phenylalanine intake with supplementation of a synthetic phenylalaninefree amino acid mixture., Phenylketonuria (PKU) is an autosomal recessive metabolic genetic disorder. Untreated, PKU can lead to mental retardation and behavioural problems., Diseases [C] - Nutritional and Metabolic Diseases [C18] | | | | |
ChiCTR-TRC-12002629: Randomised-controlled study on effectiveness of the Multidisciplinary Assessment and Psychosocial Intervention Program (MAP) |
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| Recruiting | 4 | 110 | | Drug treatment and time-limited psychosocial inter ;Drug treatment and time-limited psychosocial inter | nil; None, nil | Common Mental Disorders e.g. Anxiety, Depression | | | | |
2013-002720-16: EMPHAS I Evaluation of Methylphenidate in adults with ADHD and Substance Use Disorder EMPHAS IUtvärdering av metylfenidat hos vuxna med ADHD och substansberoende. |
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| Ongoing | 4 | 200 | Europe | | Stockholms Läns Sjukvårdsområde (SLSO), Stockholms Läns Landsting, Beroendecentrum Stockholm | ADHD, Attention Deficit Hyperactivity Disorder, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Ongoing | 4 | 100 | Europe | Baclofen, Tablet, Baclofen - generic product | Central and North West London NHS Foundation Trust | GHB/GBL Withdrawal Syndrome, Using GHB/GBL repeatedly can cause severe withdrawal symptoms, including insomnia, anxiety, tremors, and increased heart rate and blood pressure, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Ongoing | 4 | 40 | Europe | Priadel, Prolonged-release tablet, Priadel | University of Oxford, Wellcome Trust | Bipolar disorder with current mood instability, Mood disorder characterised by periods of abnormally high and/or low mood., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2014-002451-26: The effect of ketamine on suicidality KETAMIININ VAIKUTUS ITSETUHOISUUTEEN |
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| Ongoing | 4 | 72 | Europe | Solution for infusion, Ketalar | Department of Psychiatry, Helsinki University Central Hospital, Department of Psychiatry, Helsinki University Central Hospital | Depression, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2014-002002-20: A multicentre randomized double-blind placebo controlled discontinuation trial of methylphenidate |
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| Ongoing | 4 | 120 | Europe | Capsule, hard, Concerta | UMCG, ZonMw, Shire | attention-deficit/hyperactivity disorder, attention-deficit/hyperacitivity disorder (ADHD), Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2015-001639-19: Transcranial direct current stimulation and venlafaxine in the treatment of depression |
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| Ongoing | 4 | 60 | Europe | Capsule, hard, Venlafaxin Mylan 75 mg | Národní ústav duševního zdraví, Agentura pro zdravotnický výzkum České republiky | Depressive disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2014-004448-37: Brain inflammation in patients with chronic fatigue syndrome |
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| Ongoing | 4 | 20 | Europe | [11C]PK11195, [11C]PK11195, Injection | University Medical Center Groningen, University Medical Center Groningen | Chronic Fatigue Syndrome, Chronic Fatigue Syndrome, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2014-003651-54: Off-label risperidone in children and adolescents (ORCA): Discontinuation study Off-label risperidon bij kinderen en adolescenten (ORKA): afbouw studie |
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| Ongoing | 4 | 120 | Europe | risperidone, Oral solution | UMCG, ZonMW | no specific condition, we will investigate children who have been using risperidone on an off-label basis for at least one year., no specific condition, we will investigate children who have been using risperidone on an off-label basis for at least one year., Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2005-005330-12: Omega-3 Fatty Acids Supplementation for Adolescent Boys with Attention Deficit Hyperactivity Disorder : a double-blind, randomized controlled trial |
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| Ongoing | 4 | 60 | Europe | Eye Q, | King\'s College London (IOP) | Attention deficit / hyperactivity disorder (ADHD) is defined by DSM-IV criteria, which shows inattention, hyperactivity and impulsivity.ADHD is one of the most common child psychiatric disorders, more likely to be seen in males, and the prevalence is estimated approximately 5% in the UK (NICE ADHD guideline).ADHD is often prominent in early childhood and persist through adolescence to adulthood. | | | | |
2006-005216-27: Selkäytimeen annettu entsyymikorvaus mukopolysakkaridoosi I:n selkäytimen puristuman hoidossa. Kansainvälinen monikeskustutkimus. A study of intrathecal enzyme replacement therapy for spinal cord compression in mucopolysaccharidosis I, MIRC-001. |
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| Ongoing | 4 | 1 | Europe | Aldurazyme | HUS, Hospital for Children and Adolescents | Mucopolysaccharidosis I H/S, lysosomal storage disease with clinical manifestations such as progressive joint stiffness, growth retardation, corneal clouding, hepatosplenomegaly, cardiac and respiratory dysfunction, and in severe fore, mental retardation | | | | |
2007-004528-19: Electrophysiological measurement of anterior cingulate cortex (ACC) function in schizophrenic patients treated with Seroquel® or Fluanxol® |
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| Ongoing | 4 | 50 | Europe | Seroquel (Quetiapine), Fluanxol (Flupentixol), Seroquel, Fluanxol, Seroquel, Fluanxol | University of Wuerzburg | schizophrenia (295.10, 295.20, 295.30, 295.90 according to Diagnostic and Statistical Manual of Mental Disorders- Fourth Edition (DSM-IV) | | | | |
2007-005451-42: Long-term use of antipsychotics for behavioral symptoms in patients with mental retardation; a controlled discontinuation study |
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| Ongoing | 4 | 100 | Europe | Capsule* | University Medical Center Groningen | Mental retardation | | | | |
2014-003718-10: off-label use of risperidone in people with intellectual disability: A discontinuation study Off-label gebruik van risperidon door mensen met een verstandelijke beperking: een afbouwstudie |
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| Ongoing | 4 | 120 | Europe | Risperidone, | UMCG, ZonMW, Het Zorgondersteuningsfonds | no specific condition, we will investigate people with intellectual disability who have been using risperidone on an off-label basis for at least one year. | | | | |
| Ongoing | 4 | 44 | Europe | Capsule, hard, Acnamino MR 100mg capsules | King's College London, South London and Maudsley NHS Foundation Trust, NIHR BRC | Depression, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2011-001088-28: Trial to study the use of injectable buprenorphine in patients who persist in using illicit heroin to find an acceptable dose that could help reduce the use of illicit heroin |
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| Ongoing | 4 | 10 | Europe | Buprenorphine, Injection, Temgesic Injection 1ml | South London and Maudsley NHS Foundation Trust, King's College London, Action on Addiction & National Addiction Centre | Addiction to illicit heroin, Addiction to illicit heroin, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2015-004271-78: Randomised controlled trial of the short term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder |
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| Ongoing | 4 | 200 | Europe | Concerta XL 18 mg prolonged-release tablets, Tablet, Concerta XL | King's College London, NIHR EME | Attention Deficit Hyperactivity Disorder (ADHD), ADHD, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2015-000502-19: Effects of sex hormones on serotonin synthesis and degradation measured with positron emission tomography Effekte von Sexualhormonen auf Serotoninsynthese und -Abbau, gemessen mit der Positronen-Emissions-Tomographie |
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| Ongoing | 4 | 92 | Europe | Finasteride, Orgametril, Estradot, Estradiol hemihydrate, Estradiol, 12.352, Injection, Tablet, Transdermal patch, Transdermal gel, Nebido, Finasteride, Orgametril, Androcur, Cerazette, Decapeptyl, Estradot, Estrofem, Estrogel, Testogel | Medical University of Vienna, Department of Psychiatry and Psychotherapy, FWF | Gender Dysphoria (Female-to-male transsexuals and male-to-female transsexuals), A person who has a strong conviction of belonging to the opposite sex and whants to live and be accepted as a member of the opposite sex, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2013-000338-37: Evaluation of the necessity of a pharmacological treatment with antipsychotics for the prevention of relapse in long-term stabilized schizophrenic patients: a randomized, single-blind, longitudinal trial Evaluation der Notwendigkeit einer antipsychotischen Erhaltungstherapie zur Rückfallprophylaxe bei langfristig stabilen schizophrenen Patienten – eine einfach-verblindete, randomisierte, Pilotstudie |
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| Not yet recruiting | 4 | 25 | Europe | Capsule, hard, Tablet, Capsule, Oral drops, Injection, Chlorprothixen, Sertindol | Technische Universität München, vertreten durch das Klinikum rechts der Isar, Deutsche Forschungsgemeinschaft (DFG) | schizophrenia or schizoaffective disorder in remission for at least 3 years under a stable antipsychotic medication., schizophrenia or schizoaffective disorder in remission for at least 3 years under a stable antipsychotic medication., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2015-001599-23: Imaging of brain inflammation in schizophrenic patients treated with simvastatin |
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| Ongoing | 4 | 75 | Europe | [11C]PK11195, [11C]PK11195, Injection | University Medical Center Groningen, NWO (Nederlandse Organisatie voor Wetenschappelijk Onderzoek) | Schizophrenia, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2014-005366-30: RESOLVING THE NEUROBIOLOGICAL MECHANISMS OF ANXIETY DISORDERS – BRAIN IMAGING SUB-STUDY |
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| Ongoing | 4 | 70 | Europe | Escitalopram, Tablet | University of Helsinki, Jane and Aatos Erkko Foundation | Social Anxiety disorder, Social Anxiety disorder, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2016-001217-25: Emotion, Serotonin and Premenstrual Dysphoric Disorder (EmSeP) |
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| Not yet recruiting | 4 | 50 | Europe | Cipralex, N06AB10, Tablet, Cipralex - Escitalopram (Lundbeck) | Uppsala University, Swedish Research Council | Premenstrual Dysphoric Disorder, Mood disorder with onset of mood and physical symptoms in the luteal phase of the menstrual cycle, a decline in symptom severity after onset of menstruation., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2016-001637-27: Lithium versus Quetiapine in Treatment Resistant Depression. |
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| Ongoing | 4 | 276 | Europe | Lithium carbonate, Quetiapine, Lithium citrate, Tablet, Syrup | South London and Maudsley NHS Foundation Trust, King's College London, National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme | Treatment resistant major depressive disorder (single episode or recurrent). Treatment resistant depression, defined as failure to respond to two or more adequate doses of antidepressant in the current episode, Treatment resistant depression: where the person with depression has not responded adequately to two or more antidepressants given in the current episode of depression., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Ongoing | 4 | 479 | Europe | Mirtazapine Hexal, Sertralin Hexal, Citalopram Hexal, Fluoxetin EG, Tablet, Film-coated tablet, Capsule, Mirtazapine Hexal, Sertralin Hexal, Citalopram Hexal, Fluoxetin EG | PRIMENT Clinical Trials Unit, UCL, National Institute of Health Research | Depression, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR-IPR-17013122: The effects and safety of topiramate or metformin on obesity induced by antipsychotics in patients with mental disorders: a randomized clinical trial |
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| Completed | 4 | 62 | | Topiramate ;Metformin | Huaian 3rd People's Hospital, Jiangsu Province; Huaian 3rd People's Hospital, The sources of funding were mainly from huaian city science and technology bureau and huaian 3rd people's hospital, Jiangsu Province | Obesity caused by antipsychotics | | | | |
2016-000565-23: TAILOR - an experimental study comparing discontinuation with maintenance therapy of antipsychotic medication in patients with newly diagnosed schizophrenia or schizophrenia-like psychosis without psychotic symptoms |
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| Ongoing | 4 | 250 | Europe | | Trygfonden, Region Hovedstaden, Regionernes Medicin Pulje | Patients with newly diagnosed schizophrenia or schizophreniform psychosis in remission of psychotic symptoms, Patients with newly diagnosed schizophrenia or similar conditions, who no longer experience psychotic symptoms, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2016-002161-56: Towards the understanding of neuronal mechanisms of compulsive sexual behaviors - pharmacotherapy Badania neuronalnych mechanizmów kompulsywnych zachowań seksualnych - farmakoterapia |
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| Ongoing | 4 | 75 | Europe | Natrexone Hydrochloride Accord, Coated tablet, Parogen, Naltrexone Hydrochloride Accord | Mateusz Gola, Mateusz Gola | compulsive sexual behavior (hypersexual disorder) kompulsywne zachowania seksualne (zaburzenie hiperseksualne), compulsive sexual behavior (sex addiction) kompulsywne zachowania seksualne (uzależnienie od seksu), Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2016-004884-38: Evaluation of the effectiveness of loxapine in agitated patients with personality disorder Evaluación de la eficacia de la loxapina en pacientes agitados con trastorno de personalidad |
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| Ongoing | 4 | 30 | Europe | Inhalation powder, pre-dispensed, ADASUVE 9.1 mg inhalation powder, pre-dispensed | Vall d'Hebron University Hospital, Vall d'Hebron University Hospital | Acute pre/agitated patients with personality disorder Agitación en pacientes con trastorno de personalidad., Patients with personality disorder that arrive to the ER with an acute pre/agitation state Pacientes con trastorno de personalidad que acuden a urgencias en un estado de agitación o pre-agitación agudo., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-003115-20: Effectiveness of haloperidol for the treatment of acute confusional state (delirium) in patients treated at the intensive care |
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| Ongoing | 4 | 742 | Europe | Solution for infusion, Haloperidol | Erasmus Medical Center Rotterdam, ZonMw | Delirium, Acute confusion, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-004064-35: Liraglutide and the management of overweight and obesity in people with schizophrenia |
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| Not yet recruiting | 4 | 60 | Europe | Saxenda, Placebo, Injection, Saxenda | Southern Health NHS Foundation Trust, Novo Nordisk limited | Schizophrenia, schizoaffective disorder or first episode psychosis, Severe mental illness, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-004706-18: Long acting naltrexone for opioid addiction: the importance of mental, physical and societal factors for sustained abstinence and recovery |
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| Not yet recruiting | 4 | 150 | Europe | Vivitrol (Extended-release naltrexone hydrochloride for extended-release injectable suspension), N07BB04, Injection, Vivitrol | Akershus University Hospital, Norwegian Research Council, Akershus University Hospital, Haukeland University Hospital, Sørlandet Hospital Trust, Vestfold Hospital Trust, Oslo University Hospital Trust | Opioid addiction, Addiction to heroin and other opioids, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2018-000178-31: Metabolic Dysfunctions Associated with Pharmacological Treatment of Schizophrenia Alteraciones metabólicas asociadas al tratamiento farmacológico de la esquizofrenia |
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| Ongoing | 4 | 48 | Europe | Olanzapine, Aripiprazole, Tablet, Olanzapine, Aripiprazole | Fundación para la Investigación e Innovación Biosanitaria de Asturias (FINBA), Fundación para la Investigación e Innovación Biosanitaria de Asturias (FINBA) | Schizophrenia Esquizofrenia, Schizophrenia Esquizofrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-002097-38: SAM study: an epigenetic therapy for depression after childhood trauma |
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| Ongoing | 4 | 100 | Europe | S-Adenosylmethionine, Tablet | University Medical Centre Utrecht, ZonMw, Hersenstichting, University Medical Centre Utrecht | Bipolar depression, depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-005100-99: Pharmacoepidemiology and pharmacogenetics of antidepressant treatment for depressive disorders Masennuslääkehoidon farmakoepidemiologia ja -genetiikka (PEGAD) |
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| Ongoing | 4 | 1000 | Europe | All antidepressants (ATC: N06A) marketed in Finland, including all their trade names | Helsinki University and University Hospital | Depression (ICD-10 F32 and F33). Clinically diagnosed depression (F32-33), with symptom severity equaling or exceeding score 10 in the Patient Health Questionnaire (PHQ-9), Depression Depressio, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2013-002386-18: Connectivity of a network associated with rest and inhibition of responses under the influence of atomoxetine/placebo in patients with attention-deficits/hyperactivity disorder- a pharmacological fMRTI study including a scan measuring brain activity while participants are in a resting state and while performing an inhibitory control task |
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| Not yet recruiting | 4 | 52 | Europe | Atomoxetine, 60775.04.00, Capsule, Strattera | RWTH Aachen Clinical Trials Center Aachen (CTC-A), RWTH Aachen Clinical Trials Center Aachen (CTC-A) | Patients with Attention-Deficit/Hyperactivity Disorders (ADHD), Patients with ADHD which is a disorders causing inattention, hyperactivity and impulsivity, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-004984-11: "Study of maintenance of the efficacy and adverse effects of pharmacological treatments in sex offenders with paraphilia" " Etude de maintien de l'efficacité et des effets indésirables des traitements pharmacologiques chez les délinquants sexuels atteints de paraphilie " |
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| Not yet recruiting | 4 | 200 | Europe | | ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP), DGOS | Sexual offenders with paraphilia Délinquants sexuels atteints de paraphilie, Sex offenders with paraphilie Délinquants sexuelles paraphiliques, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2018-002267-25: THE EFFECT OF GENETIC AND EPIGENETIC DISPOZITIONS ON THE EFFICIENCY AND SAFETY OF OLANZAPINE PSYCHOSIS THERAPY VLIV GENETICKÝCH A EPIGENETICKÝCH DISPOZIC NA ÚČINNOST A BEZPEČNOST LÉČBY PSYCHÓZ OLANZAPINEM |
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| Not yet recruiting | 4 | 200 | RoW | Tablet | Fakultní nemocnice Brno, Fakultní nemocnice Brno/Masarykova univerzita | Psychoses, Psychoses, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2017-004834-26: What is the influence on the amount of clozapine in a patient's blood whenclozapine is used once daily instead of twice daily? Wat is het effect op de hoeveelheid clozapine in het bloed als clozapine éénkeer per dag wordt gebruikt in plaats van twee keer per dag? |
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| Not yet recruiting | 4 | 50 | Europe | clozapine | Albert Schweitzer hospital, Scientific committee of the Albert Schweitzer hospital | Schizophrenia Schizofrenie, Schizophrenia Schizofrenie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-004030-28: Changes in mental capacity and weight gain during antidepressant treatment. |
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| Ongoing | 4 | 320 | Europe | Tablet, Brintellix | Psychiatric Research Unit, Psychiatric Research Unit | Major Depressive Disorder., Major Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-003705-17: Hydrocortisone as co-treatment to prevent neuropsychiatric adverse effects of dexamethasone. Hydrocortison als co-medicatie om nadelige neuropsychiatrische effecten van dexamethason tegen te gaan. |
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| Not yet recruiting | 4 | 180 | Europe | Tablet, Hydrocortison Tiofarma 20 mg, tabletten | LUMC, ZonMw | Neuropsychiatric adverse effects which can be caused by dexamethasone. For example delirium, anxiety, depression, mania and psychosis. But also cognitive impairment and sleep disturbance. Psychiatrische klachten die kunnen ontstaan bij dexamethason gebruik, zoals delier, angst, depressie, manie en psychoses. Ook cognitieve klachten en slaap klachten., Neuropsychiatric adverse effects which can be caused by dexamethasone. For example delirium, anxiety, depression, mania and psychosis. But also cognitive impairment and sleep disturbance. Psychiatrische klachten die kunnen ontstaan bij dexamethason gebruik, zoals delier, angst, depressie, manie en psychoses. Ook cognitieve klachten en slaap klachten., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2017-002406-12: HAMLETT. Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment. A study comparing continuation versus discontinuation/dose reduction of antipsychotic medication in patients remitted after a first episode of psychosis HAMLETT. Handling Antipsychotic Medication: Lange termijn evaluatie van specifiek toegepaste medicatie. Vergelijking tussen het doorgaan met antipsychotische medicatie bij patiënten die hersteld zijn van eerste psychotische episode en vroegtijdig afbouwen/stoppen. |
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| Not yet recruiting | 4 | 512 | Europe | RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE, CID5073, CID135398745, CID5002, CID60795, CID3559, CID5355, CID115237, CID16362, CID213046, CID135398737, CID2159, CID5467, CID60149, CID667467, CIS5311507, Tablet, RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE | University Medical Center Groningen, ZonMw | HAMLETT compares regular treatment guidelines for patients in remission after a first episode of psychosis, namely continuation with antipsychotic medication for at least one year, with early dose reduction/discontinuation. HAMLETT vergelijkt de reguliere behandeling van patiënten in remissie na een eerste psychotische episode zoals beschreven in de richtlijnen, namelijk het continueren van antipsychotica voor minstens 1 jaar, met het vroegtijdig afbouwen/stoppen met medicatie., HAMLETT compares continuation versus early discontinuation of antipsychotic medication in patients who have recovered from their first episode of psychosis. HAMLETT vergelijkt de reguliere behandeling van patiënten die hersteld zijn van een eerste psychose, namelijk minimaal 1 jaar antipsychotica gebruiken, met vroegtijdig afbouwen/stoppn met medicatie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 60 | Europe | DM-Aripiprazole, DM-Olanzapine, DM- Quetiapine, DM-Risperidone, Tablet, Aripiprazole, Olanzapine, Quetiapine, Risperidone | Otsuka Pharmaceutical, Otsuka Pharmaceutical | Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-002232-82: Downstream targets of SSRI effect in treatment of Major Depressive Disorder |
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| Ongoing | 4 | 20 | Europe | [11C]AZ10419369, Escitalopram, Solution for injection, Tablet | Karolinska Institutet, Soderstrom-Konig foundation, Thurings foundation | Major depressive disorder (MDD), Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-001023-13: PAX-D: Randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression |
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| Ongoing | 4 | 204 | Europe | Pramipexole 0.18mg Tablets, Pramipexol Aurobindo 0.18 mg, Pramipexole Aurobindo 0.18 mg, Pramipexole 0.7mg Tablets, Pramipexol Aurobindo 0.7 mg, Pramipexole Aurobindo 0.7 mg, Tablet, Pramipexole 0.18mg Tablets, Pramipexol Aurobindo 0.18 mg, Pramipexole Aurobindo 0.18 mg, Pramipexole 0.7mg Tablets, Pramipexol Aurobindo 0.7 mg, Pramipexole Aurobindo 0.7 mg | University of Oxford / Clinical Trials and Research Governance, National Institute for Health Research (NIHR) | Treatment resistant depression, Clinical depression that has not responded to two antidepressant treatments, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-003128-19: Biomarkers in patients with Schizophrenia responding to Clozapine treatment Biomarkører hos patienter med Skizofreni der responderer på behandling med clozapin |
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| Not yet recruiting | 4 | 200 | Europe | clozapine, Tablet | Psykiatrisk Center Glostrup, Mental Health services, Capital region of Denmark | schizophrenia skizofreni, Conditions with cronic psychotic symptoms Lidelser med kroniske psykotiske symptomer, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2013-000970-31: Randomized, placebo-controlled multicenter trial of lithium plus treatment as usual (TAU) for acute suicidal ideation and behaviour in patients with suicidal major depressive episode |
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| Not yet recruiting | 4 | 254 | Europe | Capsule, Quilonum retard | Technische Universität Dresden, Bundesministerium für Bildung und Forschung, American Suicide Foundation | Diagnosis of a major depressive episode; inpatient at screening visit; suicidal ideation/behaviour present defined by a clinical rating of ≥ 8 on the Sheehan Suicidality Tracking Scale (S-STS) at screening and a rating of ≥20 on the Montgomery Asberg Depression Scale (MADRS) at both screening and baseline visits; both gender, age ≥18 years., patients who are severely depressive and have suicidal ideation or behaviour, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-002776-14: Inflammation-based stratification for add-on anti-inflammatory therapy in psychosis. Inflammatie-gebaseerde stratificatie voor toegevoegde dubbele immuungerichte behandeling in psychose |
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| Not yet recruiting | 4 | 235 | Europe | Celecoxib, Minocycline, Capsule, Tablet, Celecoxib, Minocycline | CAPRI-Universiteit Antwerpen, UPC Duffel | Psychosis spectrum disorders, i.e. schizophrenia, psychotic disorders, schizoaffective disorders, etc., Psychosis Psychose, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 8 | Europe | Tablet, Propranolol HCl | TNO, TNO | Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-000102-28: Does the glucagon-like peptide-1 receptor agonist semaglutide prevent deterioration of metabolic state in prediabetic or diabetic patients with schizophrenia treated with the antipsychotic compounds clozapine or olanzapine? Kan tillægsbehandling med glukagonlignende peptid-1 receptoragonisten semaglutid forebygge forværring af metaboliske forstyrrelser hos prediabetiske og diabtetiske skizofrene patienter, der er i behandling med olanzapin eller clozapin? |
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| Not yet recruiting | 4 | 104 | Europe | Suspension for injection in pre-filled pen, Ozempic | Mental Healt Center Copenhagen, Novo Nordisk, Region Hovedstaden Psykiatri | Schizophrenia spectrum disorder F20-F29, Mental Health Psykisk sygdom, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-004018-33: Prefrontal brain networks for cognitive flexibility in cognitive task for humans. |
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| Ongoing | 4 | 40 | Europe | Seropram, Film-coated tablet, Concentrate for solution for infusion, Cipralex, Seropram | Department of Psychiatry and Psychotherapy, Medical University of Vienna, Medical University of Vienna | Major depressive disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 15 | Europe | Tablet, Propranolol HCl | TNO, TNO | Post-traumatic stress disorder., Post-traumatic stress disorder., Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2020-005726-29: An open label signal detection study to evaluate the effects of cariprazine on cognitive functioning in patients with schizophrenia in need of adjustment of oral antipsychotic treatment |
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| Not yet recruiting | 4 | 20 | Europe | Capsule, hard, Reagila | Medical University Innsbruck, Gedeon Richter Plc. | Schizophrenia, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-005633-33: Prediction of ECT treatment response and reduction of Cognitive Side-effects using EEG and Rivastigmine |
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| Not yet recruiting | 4 | 100 | Europe | Rivastigmine, Transdermal patch, Rivastigmine | University Medical Center Groningen, Netherlands Organization for Scientific Research | A depressive disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-000712-30: Cortisol in personalized treatment for posttraumatic stress disorder (PTSD) Cortisol in persoonsgerichte behandeling voor posttraumatische stressstoornis (PTSS) |
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| Not yet recruiting | 4 | 190 | Europe | Hydrocortison CF, RVG 50730, Capsule, Hydrocortison CF | Radboudumc, ZonMw | Posttraumatic Stress Disorder (PTSD) Posttraumatische Stressstoornis (PTSS), Posttraumatic Stress Disorder (PTSD) Posttraumatische Stressstoornis (PTSS), Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR2000032283: A multicenter study for the injection of rat nerve growth factor in the treatment of temporary mental retardation in children |
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| Recruiting | 4 | 20 | | Routine rehabilitation treatment + Injection of rat nerve growth factor ;Routine rehabilitation treatment | The First Affiliated Hospital of Anhui Medical University; The First Affiliated Hospital of Anhui Medical University, Enterprise financing | Temporary mental development disorder in children | | | | |
2021-001268-58: Investigation of effects of cariprazine in patients with mitochondrial schizophrenia A cariprazine hatásának vizsgálata mitochondriális dysfunkcióval asszociált schizophreniában |
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| Not yet recruiting | 4 | 10 | Europe | Reagila, Capsule, Reagila | Semmelweis University, STIA-POC-2020, Semmelweis University, STIA-POC-2020, Gedeon Richter | Mitochondrial disease associated schizophrenia Mitochondrialis betegséghez társuló schizophrenia, schizophrenia associating with mitochondrial disease schizophrenia, amely mitochondrialis betegséghez társul, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2021-000862-14: Effects of low dose Aspirin in bipolar disorder – a randomized controlled trial |
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| Not yet recruiting | 4 | 250 | Europe | Capsule, Hjertemagnyl | Copenhagen Affective Disorder research Center (CADIC),, Region Hovedstadens Psykiatri | Bipolar disorder, Bipolar disorder is a common psychiatric disorder, formerly known as manio-depressive disorder.It has a life-long course characterized by high risk of recurrence of manic and depressive episodes., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-005450-18: Can we improve antipsychotic medication safety by measuring medication blood concentration in children and adolescents. |
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| Ongoing | 4 | 140 | Europe | Tablet, Risperidone | Erasmus MC, Erasmus MC | irritability in autism spectrum disorder, Irritability and aggression in children with autism., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-001817-35: Treatment of opioid dependency in patients with chronic pain: a comparative study between suboxone and methadone. Behandeling van opiaatafhankelijkheid bij pijn: een vergelijkende studie met suboxone en methadon. |
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| Ongoing | 4 | 100 | Europe | Methadone, Sublingual tablet, Tablet, Suboxone, Methadone | Radboud University Medical Center, Dutch Research Council (NWO) | Opioid use disorder Stoornis in het opioïdgebruik, Dependence on opioids Afhankelijkheid aan opiaten, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR1900025810: The effect of Shexiang Tongxin Droping Pills on coronary microvascular dysfunction (CMVD) among those with mental disorder and non-obstructive coronary artery disease based on stress cardiac magnetic resonance images-a study protocol |
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| Not yet recruiting | 4 | 72 | | Shexiang Tongxin Droping Pills combined with other drug treatment group ;Nicroandil combined with other drug treatment group | Beijing Anzhen Hosptial, Capital Medical University; Beijing Anzhen Hosptial, Capital Medical University, Coronary microvascular disease innovation foundation of 2018 | Coronary microvascular disease | | | | |
2021-003816-20: Effect of lurasidone on cerebral structure in patients with recent-onset schizophrenia Impatto della terapia antipsicotica con lurasidone sulla struttura cerebrale dei pazienti con schizofrenia ad esordio recente |
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| Not yet recruiting | 4 | 20 | Europe | Latuda, [Lurasidone], Film-coated tablet, LATUDA - 37 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER ALU/ALU - 28X1 COMPRESSE (DOSE UNITARIA), LATUDA - 18,5 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER ALU/ALU - 1X28 COMPRESSE (DOSE UNITARIA), LATUDA - 74 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER ALU/ALU - 28X1 COMPRESSE (DOSE UNITARIA) | FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Società Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. - Viale Amelia, 70 - Roma | Schizophrenia Schizofrenia, Schizophrenia Schizofrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-004404-18: Effect of antipsychotic therapy with aripiprazole long-acting on the brain structure of patients with a first episode of schizophrenia Impatto della terapia antipsicotica con aripiprazolo in formulazione a rilascio prolungato sulla struttura cerebrale dei pazienti al primo episodio di schizofrenia |
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| Not yet recruiting | 4 | 15 | Europe | Abilify Maintena, [Aripiprazolo long-acting], Powder and solvent for prolonged-release suspension for injection, ABILIFY MAINTENA - 300 MG - POLVERE E SOLVENTE PER SOSPENSIONE A RILASCIO PROLUNGATO PER INIEZIONE - USO INTRAMUSCOLARE - FLACONCINO (VETRO) - POLVERE: 300 MG + SOLVENTE: 2 ML - 1 FLACONCINO POLVERE + 1 FLACONCINO SOLVENTE + 1 SIRINGA CON AGO + 1 SIR, ABILIFY MAINTENA - 400 MG - POLVERE E SOLVENTE PER SOSPENSIONE A RILASCIO PROLUNGATO PER INIEZIONE - USO INTRAMUSCOLARE - FLACONCINO (VETRO) - POLVERE: 400 MG + SOLVENTE: 2 ML - 1 FLACONCINO POLVERE + 1 FLACONCINO SOLVENTE + 1 SIRINGA CON AGO + 1 SIR | FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Otsuka Pharmaceutical Italy s.r.l., Via Fabio Filzi 29, 20124 - Milano (MI) | Onset of schizophrenia Esordio di schizofrenia, Onset of symptoms of schizophrenia Prima presentazione di sintomatologia schizofrenica, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-006510-36: Exploring the relationship between gut microbiota and the efficacy of antidepressant treatment in patients with depression Verkennen van de relatie tussen darmbacteriën en de effectiviteit van behandeling met antidepressiva in patiënten met depressie |
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| Ongoing | 4 | 25 | Europe | Capsule | Radboudumc, Radboudumc | Major Depressive Disorder Major Depressive Disorder, Depression Depressie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR1900024126: The efficacy, safety and related mechanisms of bifidobacteria in the adjuvant treatment of mental disorder |
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| Recruiting | 4 | 240 | | Bifidobacterium triple live capsule ;Placebo capsule | Second Xiangya Hospital, Central South University.; Second Xiangya Hospital, Central South University., NSFC81501163 | Mental disorder | | | | |
ChiCTR2000032886: A multicenter study for mouse nerve growth factor in the treatment of provisional intellectual development disorders in children |
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| Not yet recruiting | 4 | 120 | | Routine rehabilitation treatment + mouse nerve growth factor ;Routine rehabilitation treatment | The First Affiliated Hospital of Anhui Medical University/ The Third Affiliated Hospital of Jiamusi University/ Xi'an TCM Hospital of Encephalopathy; The First Affiliated Hospital of Anhui Medical University;, Self-financing | Disorder of intellectual development, provisional | | | | |
2021-003588-85: Individualized care with antipsychotics in patients suffering from schizophrenia spectrum disorders |
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| Not yet recruiting | 4 | 100 | Europe | Olanzapine, Risperidone, Tablet, , Aripiprazole, Olanzapine, Risperidone | UCLouvain, FNRS | Schizophrenia, schizoaffective disorders,psychosis not otherwise specified, and dellusional disorders, psychosis, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-006800-34: Phase IV interventional pharmacological study to identify the changes in neuroplasticity at the cellular, molecular and neural level that occur in patients with major depression following the introduction of drug therapy with venlafaxine. Studio interventistico farmacologico di fase IV per identificare i cambiamenti di neuroplasticità a livello cellulare, molecolare e neurale che si verificano nei pazienti con depressione maggiore in seguito all’introduzione della terapia farmacologica con venlafaxina. |
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| Not yet recruiting | 4 | 30 | Europe | ZARELIS - 75 MG COMPRESSE A RILASCIO PROLUNGATO, [Venlafaxina], Prolonged-release tablet, ZARELIS - 75 MG COMPRESSE A RILASCIO PROLUNGATO 14 COMPRESSE IN BLISTER PVC/PCTFE/AL | FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, Fondazione Cariplo - Bando di ricerca 2019 “Ricerca sulla Sindrome ansioso-depressiva: prevenzione, diagnosi precoce e t | patients with major depression Pazienti affetti da depressione maggiore, Mental disorder Disturbo mentale, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2020-004172-17: Comparison of effectiveness of Electroconvulsive Therapy and Esketamine nasal spray in patients with depression |
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| Not yet recruiting | 4 | 30 | Europe | Nasal spray, Spravato | Medizinische Universität Innsbruck, Medizinische Universität Innsbruck | treatment resistant depression, treatment resistant depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-003676-13: Comparison of anesthesia with methohexital to anesthesia with a mixture of propofol and ketamin for electroconvulsive therapy |
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| Ongoing | 4 | 100 | Europe | Brevimytal, Ketanest S, Propfol Fresenius 1%, Powder for solution for injection/infusion, Solution for injection, Emulsion for injection, Brevimytal, Ketanest S, Propofol "Fresenius" 1% | Medical University of Vienna, Medical University of Vienna | severe uni- or bipolar depression (F32.2, F32.2, F33.2, F33.3, F31.4, F31.5), Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT04781998: Is Saxenda® a Viable Treatment of Obese Patients in Forensic Psychiatry? |
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| Completed | 4 | 24 | Europe | liraglutide 3 mg (Saxenda®) once-daily | Anders Fink-Jensen, MD, DMSci | Mental Disorder, Metabolic Disturbance, Feasibility, Overweight and Obesity, Liraglutide | 07/22 | 09/22 | | |
ChiCTR2100050008: The study on effects of esketamine on early postoperative mood in patients with preoperative anxiety and depression after undergoing laparoscopic total hysterectomy |
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| Not yet recruiting | 4 | 120 | | injection esketamine at 0.2mg/kg ;injection normal saline | Hefei Hospital Affiliated to Anhui Medical University; Hefei Hospital Affiliated to Anhui Medical University, Anhui Medical University | Pain and Neuropsychiatric disease | | | | |
2019-001518-40: Netherlands study of Optimal, PERsonalized Antidepressant use (OPERA-DISCONTINUATION) Nederlandse studie naar Optimaal gePERsonaliseerd Antidepressiva gebruik (OPERA-AFBOUW) |
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| Not yet recruiting | 4 | 400 | Europe | Sertraline, Citalopram, n/a, Tablet, Sertraline, Citalopram | VU Medical Center, The Netherlands Organisation for Health Research and Development (ZonMw) | Depression Depressie, Depression Depressie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR2100048875: A multicenter, randomized, double-blind, placebo-controlled trial of the efficacy and safety of agomelatine in patients with rapid eye movement (REM) sleep behavior disorder (RBD) |
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| Not yet recruiting | 4 | 50 | | Agomelatine 25mg/d, oral treatment before sleep, the dose was increased to 50mg/d after 2 weeks of treatment if no liver impairment occurs ;Placebo, oral treatment before sleep | Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Jiangsu Hansoh Pharmaceutical Group Co., Ltd | Rapid eye movement (REM) sleep behavior disorder (RBD) | | | | |
2020-003718-11: The effectiveness of pharmacological treatment with the glucagon-like peptide-1 receptor agonist Liraglutide 3mg (Saxenda®) once-daily for weight management in forensic psychiatry ER GLP-1 AGONISTEN SAXENDA ET EFFEKTIVT LÆGEMIDDEL TIL BEHANDLING AF OVERVÆGT HOS PATIENTER INDLAGT PÅ EN RETSPSYKIATRISK AFDELING? |
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| Not yet recruiting | 4 | 40 | Europe | Saxenda, Suspension for injection in pre-filled pen, Saxenda | Mental Health Center Copenhagen, Mental Health Centre Sct. Hans, Glostrup and Copenhagen | Severe mental illnessObesity, Mental HealthOvervægt, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-006108-34: Trial Examining Methods for Antidepressant Discontinuation Methoden om antidepressiva te stoppen vergeleken. De TEMPO-studie |
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| Ongoing | 4 | 200 | Europe | Paroxetine, Venlafaxine ER, Tablet | AmsterdamUMC (location VUmc), ZonMW | Major Depressive Disorder Depressie, Depression Depressie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR2100049994: The study on effects of esketamine on early postoperative mood in patients with preoperative anxiety and depression after undergoing laparoscopic total hysterectomy |
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| Recruiting | 4 | 120 | | esketamine with 0.2mg/kg ;normal saline was injected | Hefei Hospital Affiliated to Anhui Medical University; Hefei Hospital Affiliated to Anhui Medical University, Anhui Medical University | Pain and Neuropsychiatric disease | | | | |
2019-004880-33: Reward-specific changes of the chemical messenger dopamine in the brain of healthy and depressed people Veränderungen in der Menge des Botenstoffs Dopamin durch Belohnungsreize bei Aufgaben, gemessen im Gehirn gesunder und depressiver Personen |
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| Not yet recruiting | 4 | 100 | Europe | Tablet, Cipralex® 10 mg - Filmtabletten, Wellbutrin XR 150 mg - Retardtabletten | Medical University of Vienna, University Department of Psychiatry and Psychotherapy, Medical University of Vienna, University Department of Psychiatry and Psychotherapy | Major Depression Depressive Episode, Depression, a disease characterized by lowering of mood, reduction of energy, and decrease in activity. Capacity for enjoyment, interest, and concentration is reduced. Depression. Betroffene Patienten unter einer gedrückten Stimmung und einer Verminderung von Antrieb und Aktivität. Die Fähigkeit zu Freude, das Interesse und die Konzentration sind vermindert., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-005007-12: Study of Trazodone Once-a-Day for treatment of Depression in patients with breast cancer. |
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| Not yet recruiting | 4 | 100 | Europe | Trittico XR 150 mg prolonged-release tablets, Trittico XR 300 mg prolonged -release tablets, Prolonged-release tablet, Trittico XR 150 mg prolonged-release tablets, Trittico XR 300 mg prolonged-release tablets | Angelini Pharma S.p.A., Angelini Pharma S.p.A. | Major Depressive Disorder, Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2022-000696-39: Estrogen replacement therapy (ERT) for treatment of adolescent anorexia nervosa Not applicable |
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| Not yet recruiting | 4 | 30 | Europe | Estradot, G03CA03, Transdermal patch, Estradot | Helse-Nord, Helse-Nord | Anorexia nervosa Anorexia nervosa, Anorexia Anoreksi, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2022-001582-12: Open, multicenter, randomized clinical trial to evaluate the efficacy and safety of aripiprazole vs paliperidone / risperidone using multi-omics data in patients with a first psychotic episode. Ensayo clínico abierto, multicéntrico, aleatorizado para evaluar la eficacia y seguridad de aripiprazol vs paliperidona / risperidona mediante datos multi-ómicos en pacientes con un primer episodio psicótico. |
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| Ongoing | 4 | 244 | Europe | Injection, Abilify Maintena, Xeplion | Consorcio Centro de Investigacion Biomedica en Red (CIBER), Instituto de Salud Carlos III | First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-003242-20: Effects of recreational nitrous oxide use on psychomotor functioning related to driving performance Effecten van recreatief lachgasgebruik op psychomotorisch functioneren gerelateerd aan rijvaardigheid |
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| Not yet recruiting | 4 | 36 | Europe | Niontix, Medicinal gas, liquefied, Niontix | Maastricht University, Politieacademie | The impairing effects of recreational nitrous oxide use on psychomotor functioning related to driving performance and its relation to detected concentration in exhaled air De schadelijke effecten van recreatief gebruik van distikstofmonoxide op het psychomotorisch functioneren in verband met rijvaardigheid en het verband met de gedetecteerde concentratie in de uitgeademde lucht, The intoxicating effects of recreational nitrous oxide use on functions necessary for driving a car and its relationship to measured values of nitrous oxide in exhaled air De bedwelmende effecten van recreatief lachgasgebruik op functies nodig voor het besturen van een auto en de relatie hiervan tot gemeten waarden van lachgas in uitgeademde lucht, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2022-003279-41: Investigating the neuroreceptor NMDA in the brain of healthy and depressed people Untersuchung des Neurorezeptors NMDA im Gehirn gesunder und depressiver Personen |
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| Not yet recruiting | 4 | 60 | Europe | Tablet, Cipralex® 10 mg - Filmtabletten | Medical University of Vienna, University Department of Psychiatry and Psychotherapy, Medical University of Vienna, University Department of Psychiatry and Psychotherapy | Major Depression Depressive Episode, Depression, a disease characterized by lowering of mood, reduction ofenergy, and decrease in activity. Capacity for enjoyment, interest, andconcentration is reduced. Depression. Betroffene Patienten unter einer gedrückten Stimmung undeiner Verminderung von Antrieb und Aktivität. Die Fähigkeit zu Freude,das Interesse und die Konzentration sind vermindert., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2022-003237-19: The difference in the mechanism of action between two brands of dexamfetamine in adults with ADHD. Het verschil in de werkingsmechanisme tussen twee merken dexamfetamine bij volwassenen met ADHD. |
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| Ongoing | 4 | 26 | Europe | Dexamfetamine, N06BA02, Tablet, Tentin | Amsterdam UMC, Amsterdam UMC, ADHDcentraal | Attention Deficit Hyperactivity Disorder (ADHD) Aandachtstekort Hyperactiviteitstoornis (ADHD), Attention Deficit Hyperactivity Disorder (ADHD) Aandachtstekort Hyperactiviteitstoornis (ADHD), Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 20 | Europe | GLIATILIN, [n.a.], Capsule, soft, GLIATILIN - 10 CAPSULE GELATINA MOLLE 600 MG | Azienda Socio Sanitaria Territoriale di Lodi, ITALFARMACO S.p.A. | Under threshold depression of the elderly. Depressione sottosoglia dell’anziano., n.a. n.a., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
HECBA-PSY, NCT05583240: Influence of Olfaction Essential Oils on the Consumption of Benzodiazepine Receptor Agonists & Z-Drugs (BZRAs) Prescribed as " if Needed " in Psychiatric Outpatients (). |
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| Recruiting | 4 | 50 | Europe | Essences and Essential Oils | Etablissement Public de Santé Barthélemy Durand | Psychiatric Disorder, Benzodiazepine Withdrawal | 04/23 | 07/23 | | |
2022-000043-74: Effects of depression and antidepressants on infants´ adaption after birth |
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| Not yet recruiting | 4 | 150 | Europe | Antidepressants (SSRI, SNRI), Tablet | Medical University of Vienna, Medical University of Vienna | major depressive disorderpoor neonatal adaptation syndrome (after antidepressant use during pregnancy), depressionadaptation problems in infants due to antidepressants used by their mothers during pregnancy, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR2200063143: Clinical efficacy of Linaclotide in treatment of mental disease with constipation |
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| Not yet recruiting | 4 | 224 | | Linaclotide ;Polyethylene glycol 4000 powder | 984 Hospitail of Joint Logistic Support Force; 984 Hospitail of Joint Logistic Support Force, Self-raised | Constipation | | | | |
NCT01453127: DaTSCAN Imaging in Aging and Neurodegenerative Disease |
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| Enrolling by invitation | 4 | 500 | US | I-123 Ioflupane solution injection prior to SPECT scan (DaTscan), Single photon emission computed tomography (SPECT) scan | Mayo Clinic | Dementia, Parkinsonism, Mild Cognitive Impairment, REM Sleep Behavior Disorder | 12/25 | 12/25 | | |
ChiCTR2200056223: A Multicenter Observational Study of Rehabilitation Training Combined with Mouse Nerve Growth Factor for Injection in The Treatment of Children With Provisional Intellectual Development Disorders by Different Pathogenic Factors |
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| Recruiting | 4 | 300 | | Rehabilitation training+Mouse nerve growth factor for injection ;Rehabilitation training+Mouse nerve growth factor for injection ;Rehabilitation training+Mouse nerve growth factor for injection ;Rehabilitation training+Mouse nerve growth factor for injection ;Rehabilitation training+Mouse nerve growth factor for injection | Children's Hospital Affiliated to Shandong University; Children's Hospital Affiliated to Shandong University, Self-financing | Disorder of intellectual development, provisional | | | | |
PWS-GXR, NCT05657860: Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome |
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| Recruiting | 4 | 33 | US | Guanfacine Extended Release, Intuniv, Placebo | Maimonides Medical Center | Prader-Willi Syndrome, Aggression, Self-Injurious Behavior, Pathologic Processes, Behavioral Symptoms, Intellectual Disability, Neurobehavioral Manifestations, Neurologic Manifestations, Nervous System Diseases, Abnormalities, Multiple, Congenital Abnormalities, Chromosome Disorders, Genetic Diseases, Inborn, Obesity, Overnutrition, Nutrition Disorders, Antihypertensive Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Physiological Effects of Drugs, Skin-Picking | 01/24 | 01/24 | | |
ChiCTR2100048253: Research on Psychiatric Disease and Metabolism of Medical Union in Huangpu District, Shanghai |
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| Not yet recruiting | 4 | 60 | | Polyethylene glycol loxenatide injection | Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, self-funded | endocrine metabolism diseases | | | | |