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CLOZ-AID, NCT04529226: Study to Compare Clozapine vs Treatment as Usual in People With Intellectual Disability & Treatment-resistant Psychosis |
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| Active, not recruiting | 2 | 75 | Europe | Clozapine, Nemex, Leponex, haloperidol, pimozide, olanzapine, risperidone, amisulpride | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | Psychosis, Intellectual Disability | 01/25 | 12/25 | | |
NCT05321498: Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation |
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| Withdrawn | 2 | 60 | NA | XPro1595, INB03/XPro™, XENP1595, Dominant-negative Tumor Necrosis Factor (DN-TNF), Placebo, Matching Placebo | Inmune Bio, Inc. | Mild Cognitive Impairment (MCI), Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Mental Disorders | 10/23 | 10/23 | | |
| Completed | 2 | 275 | US | Common Elements Toolbox, COMET, Single-session intervention, Doing What Matters in Times of Stress: An Illustrated Guide, Self-help Plus, Guided self-help | Indiana University | Depression, Anxiety, Emotion Regulation | 05/23 | 09/23 | | |
NCT04937452: Dopaminergic Therapy for Frontotemporal Dementia Patients |
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| Active, not recruiting | 2 | 75 | Europe | Rotigotine 4Mg/24Hrs Patch, Neupro, Rotigotine 6Mg/24Hrs Patch, Placebo | I.R.C.C.S. Fondazione Santa Lucia, Alzheimer's Drug Discovery Foundation | Frontotemporal Dementia, Dementia, Aphasia, Primary Progressive, Pick Disease of the Brain, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Neurocognitive Disorders, Mental Disorders, Neurodegenerative Diseases, Frontotemporal Lobar Degeneration, TDP-43 Proteinopathies, Proteostasis Deficiencies, Metabolic Disease, Aphasia, Speech Disorders, Language Disorders, Communication Disorders, Neurobehavioral Manifestations, Neurologic Manifestations | 12/23 | 04/24 | | |
NCT05554094: Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder |
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| Recruiting | 2 | 15 | US | Psilocybin | Ohio State University | PTSD, Stress Disorders, Traumatic, Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Mental Disorder | 01/25 | 07/25 | | |
NCT04821856: Evaluation of the Effectiveness of Cannabidiol in Treating Severe Behavioural Problems in Children and Adolescents With Intellectual Disability |
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| Recruiting | 2 | 140 | RoW | Cannabidiol Oil, Placebo | Murdoch Childrens Research Institute, Monash University, University of Sydney, Deakin University | Intellectual Disability, Child Behavior Problem | 05/25 | 06/25 | | |
| Not yet recruiting | 2 | 180 | NA | TMS | Brigham and Women's Hospital, National Institutes of Health (NIH) | Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder, Mood Disorders, Psychiatric Disorder, Mental Disorder, Depression, Anxiety | 06/29 | 06/30 | | |
| Not yet recruiting | 2 | 80 | US | Transcranial magnetic stimulation, Sham transcranial magnetic stimulation | Brigham and Women's Hospital | Anxiety Disorders, Mental Disorder, Psychiatric Disorder | 08/28 | 02/29 | | |
NCT05904717: Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder |
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| Recruiting | 2 | 40 | Europe, RoW | PXS-4728 (A), Matching Placebo (B) | Pharmaxis | REM Sleep Behavior Disorder | 09/24 | 01/25 | | |
MINDFuL, NCT05318976: A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation |
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| Recruiting | 2 | 201 | Europe, Canada, RoW | XPro1595, INB03/XPro™, XENP1595, DN-TNF, Placebo, Matching Placebo | Inmune Bio, Inc. | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders, Mild Cognitive Impairment | 12/24 | 12/24 | | |
NCT05838560: Dasatinib Plus Quercetin for Accelerated Aging in Mental Disorders |
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| Recruiting | 2 | 40 | US | Dasatinib + quercetin | Washington University School of Medicine, UConn Health | Schizophrenia, Treatment Resistant Depression, Aging, Premature | 05/25 | 05/26 | | |
NCT05109364: Terazosin and Parkinson's Disease Extension Study |
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| Recruiting | 2 | 15 | US | Terazosin therapy | Cedars-Sinai Medical Center | Symptomatic Parkinson Disease, REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease | 11/25 | 11/25 | | |
NCT04218968: Cardiac Changes in Early Parkinson's Disease: A Follow up Study |
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| Enrolling by invitation | 2 | 15 | US | Carvedilol | Cedars-Sinai Medical Center | REM Sleep Behavior Disorder, Pre-motor Parkinson Disease, Symptomatic Parkinson Disease | 12/25 | 12/25 | | |
NCT04386317: Terazosin Effect on Cardiac Changes in Early Parkinson's Disease |
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| Recruiting | 2 | 15 | US | Terazosin | Cedars-Sinai Medical Center | REM Sleep Behavior Disorder, Pre-motor Parkinson's Disease, Symptomatic Parkinson Disease | 12/25 | 12/25 | | |
NCT05522387: An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease |
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| Active, not recruiting | 2 | 11 | RoW | XPro1595, INB03/XPro™, XENP1595, DN-TNF | Inmune Bio, Inc. | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 05/24 | 09/24 | | |
NCT03862950: A Trial of Metformin in Individuals With Fragile X Syndrome (Met) |
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| Recruiting | 2 | 120 | Canada | Placebo Medication, Placebo, Metformin, Glumetza, Glucophage, Fortamet | University of Alberta, St. Justine's Hospital | Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X-Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders | 06/26 | 06/26 | | |
ANT, NCT05680727: Individualized Functional Connectivity Targeting in aiTBS for Depression |
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| Recruiting | 2 | 40 | US | transcranial magnetic stimulation, TMS, theta burst stimulation, accelerated intermittent theta burst stimulation, aiTBS | Brigham and Women's Hospital | Depressive Disorder, Major, Depression, Mood Disorders, Mental Disorder, Psychiatric Disorder | 07/26 | 01/27 | | |
NCT04534023: A Clinical Study of the Efficacy of Idebenone in the Treatment of iRBD Into Synucleinopathies |
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| Recruiting | 2 | 142 | RoW | Idebenone, Placebo | Ruijin Hospital, Second Affiliated Hospital of Soochow University, Wuhan Union Hospital, China | Rapid Eye Movement Sleep Behavior Disorder, Synucleinopathy | 09/26 | 09/26 | | |
OT-DEFI, NCT05864508: Interest of Oxytocin as an Adjuvant Treatment of Psycho-educational Measures in Challenging Behaviors in Children With Autism Spectrum Disorders and Moderate to Severe Intellectual Disability: Feasibility and Safety Study. |
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| Not yet recruiting | 2 | 30 | Europe | Oxytocin nasal spray | University Hospital, Toulouse | Autism Spectrum Disorder | 12/26 | 12/26 | | |
2012-004579-37: Psilocybin as a model of psychotic illness Psilocybin jako model psychotického onemocnění |
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| Ongoing | 1/2 | 40 | Europe | Psilocybin, THC-1143G, Capsule | National Institute of Mental Health, Internal Grant Agency of the Czech Ministry of Health | Inclusion criteria:a) Men and women at age between 28 and 65 years b) healthy volunteers with negative psychiatric history (severe mental illnesses that meet the criteria of ICD 10 F0.X - F99.X) c) negative family psychiatric history in terms of psychoses up to 2nd generation of relatives Výběrová kritéria:a) Muži a ženy ve věku mezi 28 a 65 letyb) Zdraví dobrovolníci s negativní psychiatrickou anamnézou (závažná duševní onemocnění splňující kriteria MKN 10 F0.X - F99.X)c) Negativní rodinná psychiatrická anamnéza z hlediska psychóz až do příbuzných 2. Stupně, 1. Healthy volunteers without any psychiatric disorder2. Siblings, parents and grandparents must not experience schizophrenia or any other psychosis in the present or in the past 1. Zdraví dobrovolníci bez psychiatrického onemocnění2. Sourozenci, rodiče a prarodiče nesměli prodělat schizofrenii ani jiný typ psychóz v současnosti ani v minulosti, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2009-009475-35: Lack of Empathy as a Symptom in various Psychiatric Disorders |
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| Ongoing | 1/2 | 75 | Europe | oxytocin, RVG 03716, Syntocinon, Syntocinon | KARAKTER universitair centrum voor kinder- en jeudpsychiatrie | Autism Spectrum Disorder (Autism, Asperger\'s Syndrome)Conduct DisorderMild Mental Retardation | | | | |
| Not yet recruiting | 1/2 | 16 | Europe | GH001, Inhalation solution | Gh Research Limited, GH Research Limited | Treatment-resistant depression, Depression that has not responded sufficiently to previous treatment, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-002604-12: The effect of ketamine on aesthetics and role for antidepressant effects Einfluss von Ketamin auf ästhetische Prozesse und Relevanz für antidepressive Effekte |
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| Not yet recruiting | 1/2 | 65 | Europe | Ketamin hameln, 32265.00.00, Solution for injection/infusion, Ketamin-hameln | Medical University of Vienna, Medical University of Vienna, Interdisciplinary Cluster Project | Depression Depression, Depression Depression, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT06003582: Co-production and Feasibility RCT of Intervention to Improve the Mental Health of Children With a Social Worker |
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| Recruiting | 1/2 | 30 | Europe | Infant Parent Support | University of Glasgow, NSPCC, Glasgow City Council, London Borough of Bromley, University of Nottingham, Queen Mary University of London | Parent-Child Relations, Child Mental Disorder, Child Maltreatment | 11/23 | 11/23 | | |
NCT03675282: Quantitative Mapping of Substantia Nigra Iron in Parkinson's Disease (Stages I-IV, REM Sleep Behavior Disorder) and Controls |
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| Completed | 1/2 | 82 | US | (11C)PE2I, PET Scan, Ioflupane, DaT scan | Weill Medical College of Cornell University, National Institute of Neurological Disorders and Stroke (NINDS) | Parkinson Disease, REM Sleep Behavior Disorder, Healthy | 04/24 | 04/24 | | |
NCT06458686: Effect of Vitamin D Supplementation on Mental Health: An Exploratory Study on A University Students Suffering From Vitamin D Deficiency |
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| Not yet recruiting | 1/2 | 70 | NA | Vit D, Placebo | German University in Cairo, Prof. Mohamed Hassan Solayman, Clinical pharmacy Department, German University in Cairo, Prof. May Ahmed Shawki, Clinical Pharmacy Department, Ain Shams University, Egypt | Psychiatric Disorder | 06/26 | 09/26 | | |
2008-003287-18: Functional consequences of decreased RNA expression of certain GABA(A) receptor subunits in fragile X patients using Positron Emission Tomography and [11C]flumazenil. |
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| Ongoing | 1 | 30 | Europe | 11C-flumazenil, Injection* | University Antwerp, University Hospital Leuven gasthuisberg | Fragile X syndrome is the most common form of inherited mental retardation with a prevalence of 1/4000 males and 1/6000 females. Patients are characterized by a mild to severe form of cognitive impairment and light dysmorphic features. Autism-like behaviour, hyperactivity and epilepsy can also be associated with the disease. On the molecular level the disease is caused by a dynamic mutation of a CGG repeat in the 5' UTR of the FMR1 gene. | | | | |
2012-000220-18: Effects of melatonin treatment, light therapy, and sleep improvement in children with sleep onset problems Onderzoek naar de effecten van melatonine, lichttherapie en slaapverbetering in kinderen met inslaapproblemen |
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| Ongoing | 1 | 192 | Europe | Tablet, Bio-Melatonin | University of Amsterdam, University of Amsterdam, Pharma Nord | Delayed Sleep Phase Syndrome Verlaat slaapfase syndroom, Sleep onset problems Inslaapproblemen, Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2010-019420-31: ‘The influence of MAC values and behaviour of a child on emergence delirium after sevoflurane anaesthesia’ |
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| Ongoing | 1 | 40 | Europe | | | ‘Emergence delirium’ (ED) is described as a mental disorder during recovery from general anaesthesia. After the introduction of new inhalation anaesthetics such as sevoflurane, this phenomenon again gained prominence. The specific cause is unknown. Objective of the research | | | | |
2017-000687-16: Novel avenues for the rescue of intellectual disability in Down syndrome strategia farmacologiche per migliorare la disabilit¿ intellettiva nella sindrome di Down |
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| Not yet recruiting | 1 | 20 | Europe | prozac, 25970029, Oral solution, PROZAC - 20 MG/5 ML SOLUZIONE ORALE 1 FLACONE IN VETRO DA 60 ML | AOU FEDERICO II, Universit¿ Alma Studiorum Bologna | DOWN SYNDROME SINDROME DI DOWN, chromosome 21 trisomy trisomia del cromosoma 21, Diseases [C] - Nervous System Diseases [C10] | | | | |
ChiCTR-RPC-15007219: Research of the pathogenesis of REM sleep behavior disorder andits relationship with other neural degeneration diseases |
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| Not yet recruiting | 1 | 120 | | Nil | Department of Neurology, Changzheng Hospital, Second Military Medical University; Department of Neurology, Changzheng Hospital, Second Military Medical University, national natural science foundation project（81070070；81171252） | REM sleep behavior disorder; neurodegeneration disease | | | | |
2016-003529-41: What is the effect of cannabidiol on the function of microglia in patients with schizophrenia? |
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| Not yet recruiting | 1 | 36 | Europe | Cannabidiol, Capsule, hard | University Medical Center Utrecht, Netherlands Organisation for Scientific Research | Schizophrenia patients, Schizophrenia patients, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2019-000989-38: A Study Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children Ages 2–4 Years with Autism Spectrum Disorder Un estudio uqe investiga la farmacocinética, la seguridad y la tolerabilidad del balovaptán en niños de 2 a 4 años con trastorno del espectro autista |
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| Not yet recruiting | 1 | 10 | Europe | RO528-5119/F10, RO528-5119/F11, RO528-5119/F37, RO528-5119/F10, RO528-5119/F11, RO528-5119/F37, Dispersible tablet | Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd, F.Hoffman-La Roche Ltd. | Autism spectrum disorder (ASD) Trastorno del espectro autista (TEA), ASD is a neurodevelopmental disorder that impairs the ability to communicate and interact TEA es un trastorno del desarrollo neurológico que afecta la capacidad de comunicarse e interactuar, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-001337-40: STUDY TO DETERMINE EFFICACY AND SAFETY OF BXCL501 IN AGITATION ASSOCIATED WITH PEDIATRIC SCHIZOPHRENIA AND BIPOLAR DISORDER ESTUDIO PARA DETERMINAR LA EFICACIA Y LA SEGURIDAD DE BXCL501 EN LA AGITACIÓN ASOCIADA A ESQUIZOFRENIA Y TRASTORNO BIPOLAR PEDIÁTRICOS |
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| Not yet recruiting | 1 | 120 | Europe | BXCL501, Buccal film | BioXcel Therapeutics, Inc., BioXcel Therapeutics, Inc. | Subject that meets DSM-5 criteria for schizophrenia, schizoaffective, or schizophreniform disorder, or other specified/unspecified schizophrenia spectrum and/or other psychotic disorders OR Subject meets DSM-5 criteria for bipolar disorder (bipolar I or II ). Pacientes que cumplan los criterios de DSM-5 para esquizofrenia, trastorno esquizoafectivo o trastorno esquizofreniforme u otro espectro de esquizofrenia especificado/no especificado uy otros trastornos psicóticos O Pacientes que cumplan los criterios de DSM-5 para trastorno bipolar (bipolar I o II)., Schizophrenia and bipolar disorder Esquizofrenia y trastorno bipolar, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT04922593: Relative Bioavailability of LY03010 Compared to Listed Drug |
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| Completed | 1 | 281 | US | LY03010; paliperidone palmitate, INVEGA SUSTENNA | Luye Pharma Group Ltd. | Schizophrenia, Psychotic Disorders, Mood Disorders, Schizophrenia Spectrum, Mental Disorders, Antipsychotic Agents, Tranquilizing Agents, Central Nervous System Depressants, Physiological Effects of Drugs, Psychotropic Drugs, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action | 03/22 | 04/22 | | |
ChiCTR2200058387: Clinical Study of Percutaneous Acupoint Electrical Stimulation in Children with Intellectual Disability Based on Electro - optic Biofeedback Technique |
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| Recruiting | 1 | 60 | | Retain the original routine rehabilitation ;Retain the original routine rehabilitation + Percutaneous Acupoint Electrical Stimulation | Fujian University of Traditional Chinese Medicine; People ' s Hospital Affiliated to Fujian University of Traditional Chinese Medicine, self-paying | Intellectual Disability | | | | |
NCT05321602: Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder |
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| Completed | 1 | 89 | US | LY03010 156 mg treatment group, deltoid, paliperidone palmitate, LY03010 156 mg treatment group, gluteal, LY03010 351 mg treatment group, deltoid, LY03010 351 mg treatment group, gluteal | Luye Pharma Group Ltd. | Schizophrenia, Psychotic Disorders, Mood Disorders, Schizophrenia Spectrum and Other Psychotic Disorders, Mental Disorders, Antipsychotic Agents, Tranquilizing Agents, Central Nervous System Depression, Physiological Effects of Drugs, Psychotropic Drugs, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action | 09/22 | 10/22 | | |
2022-002940-27: Stem cell treatment of autism spectrum disorders (ASD) and gastrointestinal problems in children. Stamcellebehandling af autismespektrumforstyrrelser (ASF) og mave-tarmproblemer hos børn. |
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| Not yet recruiting | 1 | 10 | Europe | CSCC_ASC, CSCC_ASC5010, Concentrate and solvent for dispersion for injection | Cell2Cure ApS, Cell2Cure ApS | Children with autism spectrum disorder and gastrointestinal symptoms. Børn med autismespektrumforstyrrelser og mave-tarmproblemer., Children with autism spectrum disorder and gastrointestinal symptoms. Børn med autismespektrumforstyrrelser og mave-tarmproblemer., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT05251779: A Clinical Study on the Effects of Inhalation of Volatile Oil of Cang-Ai Via the Nose on Patients With Depression |
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| Not yet recruiting | 1 | 60 | NA | Volatile Oil of Cang-Ai, CAVO, Bergamot essential oils, Citrus bergamia | Jieqiong Cui | Depressive Disorder, Mental Disorder in Adolescence | 12/22 | 12/22 | | |
ChiCTR2100050197: The effectiveness of MICM to improve medication adherence for dual-diagnosed patients |
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| Not yet recruiting | 1 | 86 | | MOTIVATIONAL INTERVIEWING AND CONTINGENCY MANAGEMENT ;NO TREATMENT | NIL; Level of the institution：, SELF | SUBSTANCE USE DISORDER WITH ANY TYPE OF PSYCHIATRIC DISORDERS | | | | |
NCT04210713: Neuroimmune Dysfunction in Alcohol Use Disorder |
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| Completed | 1 | 142 | US | Minocycline, Sugar pill, Placebo | University of Maryland, Baltimore, National Institute on Alcohol Abuse and Alcoholism (NIAAA) | Alcohol Drinking, Alcohol-Related Disorders, Disease, Inflammation, Alcoholism, Cognitive Dysfunction, Pathologic Processes, Drinking Behavior, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder, Cognition Disorder, Neurocognitive Disorders, Minocycline, Anti-Bacterial Agents, Anti-Infective Agents | 09/23 | 09/23 | | |
| Completed | 1 | 66 | Europe | Natalizumab, Tysabri, Placebo: normal saline | King's College London, South London and Maudsley NHS Foundation Trust | Schizophrenia | 06/23 | 08/23 | | |
ChiCTR2300069453: Probiotics of Infant Gut Origin to Improve Gut and Mental Health in Adults |
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| Completed | 1 | 200 | | Bifidobacterium breve 207-110 billion cfu per day for 30 days. ;Bifidobacterium breve 207-150 billion cfu per day for 30 days. ;Lactobacillus paracasei 207-2,710 billion cfu per day for 30 days. ;Lactobacillus paracasei 207-2,750 billion cfu per day for 30 days. ;Placebo (maltodextrin) was taken per day for 30 days. | Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University; West China School of Public Health, Sichuan University, By-health Co., Ltd. | mental disease | | | | |
N-AND, NCT05273320: Clinical Trial of Nabilone for Aggression in Adults With Intellectual and Developmental Disabilities |
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| Recruiting | 1 | 30 | Canada | Nabilone, 02392925 Teva-Nabilone 0.25 mg Capsule; 02384892 Teva-Nabilone 1 mg Capsule | Hsiang-Yuan Lin | Intellectual Disability, Developmental Disability, Aggression, Behavior Problem | 03/24 | 03/24 | | |
| Not yet recruiting | 1 | 10 | NA | transcranial magnetic stimulation, TMS, accelerated intermittent theta burst stimulation, aiTBS | Brigham and Women's Hospital | Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders, Mental Disorder, Anxiety Disorders, OCD, PTSD | 04/25 | 04/26 | | |
NCT05962424: HNC: Human Neural Circuits Electrophysiology During Cognition |
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| Recruiting | 1 | 120 | US | Ketamine Hydrochloride, Ketalar | Stanford University | Psychiatric Disorder | 09/25 | 09/26 | | |
NCT05301361: Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities |
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| Enrolling by invitation | 1 | 68 | US | Methylphenidate Oral Solution | University of California, Davis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Intellectual Disability, Fragile X Syndrome, Down Syndrome, Attention Deficit Hyperactivity Disorder | 09/25 | 09/26 | | |
RBD, NCT05922995: The Effects of Tasimelteon in Participants With REM Behavior Disorder |
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| Not yet recruiting | 1 | 20 | US | Tasimelteon, Hetlioz | Brigham and Women's Hospital, Vanda Pharmaceuticals | REM Behavior Disorder | 09/26 | 12/28 | | |
ACTRN12623000716662: Effect of Addressing Quality of Life on Challenging Behaviour in Adults with Intellectual or Developmental Disability |
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| Not yet recruiting | N/A | 10 | | | Sophia Kennedy, Te Herenga Waka, Victoria University of Wellington, American Association on Intellectual and Developmental Disabilities | Challenging behaviour, Intellectual Disability, Developmental Disability | | | | |
ACTRN12623000873628: Preliminary study of The Feelings Program for Adolescents with neurodevelopmental conditions delivered in a group clinic-based setting or parent home-based setting to explore feasibility, participant experience and the effect on social emotional domains, wellbeing and mental health concurrent with delivery of the digital version of this intervention. |
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| Not yet recruiting | N/A | 20 | | | The Children's Hospital at Westmead, The Children's Hospital at Westmead | Cerebral Palsy, Mild Intellectual Disability, Autism Spectrum Disorder | | | | |
ACTRN12622000986774: A research study of behavioural activation treatment for depression for adolescents with mild to moderate intellectual disability |
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| Not yet recruiting | N/A | 30 | | | Monash University, Monash-Warwick Alliance | depression, intellectual disability | | | | |
ACTRN12623000245695: The influence of individualised strength and conditioning versus games-based training on health-related components of fitness in young people with intellectual disability |
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| Not yet recruiting | N/A | 36 | | | University of Southern Queensland, University of Southern Queensland | Intellectual disability | | | | |
ACTRN12623001055695: Bridge to Better Health: Capacity Building in Intellectual Disability Health for General Practice |
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| Not yet recruiting | N/A | 208 | | | University of Queensland, National Health and Medical Research Council | Intellectual Disability Health Care | | | | |
ACTRN12623000694617: Rau Mahara Rongomau: Online mental health support while waiting for in-person therapy |
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| Not yet recruiting | N/A | 240 | | | University of Otago, The Wise Group | Depression, Anxiety, Mental distress | | | | |
ACTRN12622001072707: Investigating the effect of an education internvention on stigma in university students towards people with mental disorders. |
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| Not yet recruiting | N/A | 317 | | | Daisy Vidal Gutierrez, Universidad de Concepcion/PROYECTO VRID 2020000137 | stigma towards mental illness | | | | |
ACTRN12622000847718: A process-based psychological treatment informed by relational frame theory for people who meet criteria for multiple psychiatric disorders |
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| Recruiting | N/A | 6 | | | Kompetenscentrum för psykoterapi, Centrum för psykitriforskning, Karlstad University, Karolinska Institutet, Region stockholm | Major Depressive Disorder , Panic Disorder, Agora Phobia, Social Anxiety Disorder, Obsessional Compulsive Disorder, Post-Traumatic Stress Disorder , Generalised Anxiety Disorder | | | | |
ACTRN12623000406606: The hearables study - addressing mental health in hearing impaired older adults through the use of hearable devices and behavioural activation (BA) therapy. |
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| Recruiting | N/A | 240 | | | University of Western Australia, National Health & Medical Research Council | Depression , Social isolation, Hearing loss, Poor quality of life | | | | |
ChiCTR-TRC-09000628: Vaginal birth after caesarean section - effect on maternal psychosocial function |
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| Completed | N/A | 262 | | repeat elective caesarean section Maximum 1 day (the birth of a baby) Attempt of vaginal delivery | The Chinese University of HK; Level of the institution：, RGC grant and CUHK | Behaviors and Mental Disorders | | | | |
ChiCTR-ICR-15006197: Clinically randomized comperative observation of acupuncture treatment of mental retardation based on GAS individualized assessment |
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| Recruiting | N/A | 70 | | acupuncture ;scalp acupuncture | Colledge of Acupuncture, Fujian University of Traditional Chinese Medicine; Colledge of Acupuncture, Fujian University of Traditional Chinese Medicine, Finacial aid from Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Science | Mental Detardation | | | | |
ChiCTR-TRC-05000735: Outcome of postnatal depression screening using Edinburgh Postnatal Depression Scale |
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| Suspended | N/A | 460 | | Postnatal depression screening programme using Edinburgh Postnatal Depression Scale (EPDS is a 10-item self-report questionnaire used for screening postnatal depression). Clinical intervention is based on the EPDS screening score and nursing assessment versus Clinical intervention is based on usual nursing assessment practice for ten minutes | Department of Health; Level of the institution：, Department of Health | Behaviors and Mental Disorders | | | | |
NCT05820269: Predictive Factors for the Outcome of Young Children Emotional and/or Behavioral Disorders After Psychotherapeutic Intervention |
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| Completed | N/A | 272 | Europe | parents-child psychotherapy | University Hospital, Montpellier | Behavioral Disorders, Emotional Disorder of Childhood | 12/13 | 12/13 | | |
ChiCTR-CCC-13003445: Abberant expression of peripheral microRNA in Non-syndromic/non-specific Mental Retardation and its clinical application study |
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| Completed | N/A | 120 | | observation ;NA | 102th hospital of Chinese People’s Liberation Army, clinical hospital of mental health affiliated to the Second Military Medical University; 102th Hospital of Chinese People's Liberation Army, *Medical, pharmaceutical and public health fund of Nanjing Military Command Area | Non-syndromic/non-specific Mental Retardation | | | | |
ChiCTR-ECH-14004633: The incidence and psychological-psychiatric disorders of globus: a multicenter prospective investigation in China |
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| Recruiting | N/A | 200 | | N/A | Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical university; Guangzhou First Municipal People's Hospital, Guangzhou Nan Sha Center Hospital Affiliated to Guangzhou Medical university, Self-funding | Globus | | | | |
| Completed | N/A | 120 | | Peer Support Worker Training ;No intervention | 1) Prof. Winnie Wing Sze MAK, Department of Psychology, The Chinese University of Hong Kong; 2) New Life Psychiatric Rehabilitation Association;; Level of the institution：, None | Mental and behavioral disorder | | | | |
ChiCTR-IOR-15006463: The analysis for the perioperative efficacy of dexmedetomidine on modified electroconvulsive Therapy |
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| Recruiting | N/A | 150 | | dexmedetomidine 0.5ug/Kg ;dexmedetomidine 0.2ug/Kg ;saline | Third Affiliated Hospital of Sun Yat-sen University; Third Affiliated Hospital of Sun Yat-sen University, Self-financing | Mental disease | | | | |
| Completed | N/A | 29 | NA | Guided physical activity, Standard physical activity | Fundación para la Investigación del Hospital Clínico de Valencia | Severe Mental Disorder, Obesity | 06/16 | 06/16 | | |
| Active, not recruiting | N/A | 77000 | Europe | IPS | Norwegian Institute of Public Health, Nordlandssykehuset HF, University of Tromso, London School of Economics and Political Science, University of Melbourne, St George's Healthcare NHS Trust, The University of New South Wales | Severe Mental Disorder | 12/16 | 12/22 | | |
ChiCTR-COC-15006544: The expression level and genetic polymorphism of blood neuregulin-1 in patients with various psychiatric disorders. |
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| Not yet recruiting | N/A | 320 | | N/A ;N/A ;conventional antipsychotic therapy ;none | The First Hospital of Hebei Medical University; The First Hospital of Hebei Medical University, National Natural Science Foundation of China (81301150); Hebei ProvinceScience Foundation of China (H2013206215) | psychiatric disorders | | | | |
REAL-SMART, NCT06262958: Recognition and Early Intervention for Alcohol and Substance Abuse in Adolescence in Adolescent |
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| Recruiting | N/A | 800 | Europe | ASSIST, Treatment as usual | Kuopio University Hospital | Alcoholism, Substance Abuse, Alcohol Dependence, Alcohol-Related Disorders, Substance Use Disorders, Adolescent Behavior, Adolescent Problem Behavior | 06/30 | 06/30 | | |
| Recruiting | N/A | 300 | | Nil | the Third Affilited Hospital of Zhengzhou University; the Third Affilited Hospital of Zhengzhou University, Self-finance | Intellectual disability | | | | |
| Completed | N/A | 385 | Europe | Fibroscan, Blood sample | Centre Hospitalier Esquirol | Severe Bipolar I Disorder (Diagnosis), Bipolar I Disorder, Most Recent Episode Mixed, in Remission, Depression Psychotic Feature, Mood-Incongruent Delusion | 02/18 | 07/21 | | |
ChiCTR-CRC-17010726: Effects of long - term administration of methamphetamine on neuro - endocrine - immune networks |
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| Recruiting | N/A | 200 | | Nil | The Fourth People's Hospital Of Chengdu; The Fourth People 's Hospital Of Chengdu, Hospital allocation | methamphetamine induced mental disorders | | | | |
NCT06434428: Comparison Between Intranasal vs Intravenous Dexmedetomidine for EEG Sedation of Children With Behavior Disorders. |
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| Completed | N/A | 48 | Europe | dexmedetomidine (IV), dexmedetomidine (IN) | Azienda Ospedaliera di Padova | Sedation Complication | 08/21 | 09/22 | | |
ChiCTR-INR-17013188: An intervention study of internet-based cognitive training programs for mental disorders |
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| Recruiting | N/A | 180 | | internet-based cognitive training ;games | Beijing An Ding Hospital, Capital Medical University; Beijing An Ding Hospital, Capital Medical University, Development and application of new diagnosis and treatment technology in schizophrenia or depressive disorder | mental disorders | | | | |
| Recruiting | N/A | 80 | | taken lithium carbonate orally ;taken sodium carbonate orally ;taken sodium carbonate orally ;taken sodium carbonated orlly | The Third Affilited Hospital of Zhengzhou University; The Third Affilited Hospital of Zhengzhou University, self-financing | Metal retardation | | | | |
| Active, not recruiting | N/A | 57212 | RoW | Patient with severe mental disorder without intervention | Ningbo University, The Affiliated Kangning Hospital of Ningbo University | Severe Mental Disorder, Schizophrenia, Bipolar Disorder, Schizo-Affective Psychosis, Paranoid Psychoses, Mental Retardation, Epileptic Psychosis | 12/23 | 12/26 | | |
ChiCTR-IPR-17012125: Mindfulness-based Self-compassion Program for Caregivers of People with Mental Disorders: a Pilot Study |
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| Not yet recruiting | N/A | 30 | | Mindfulness based intervention ;waitlist control | The Chinese University of Hong Kong; Level of the institution：, NA | caregivers of people with mental disorders | | | | |
| Recruiting | N/A | 180 | | No intervention | Department of Military Medical Psychology, Air Force Military Medical University; Department of Military Medical Psychology, Air Force Military Medical University, PLA Key Project BWS16J012 | Mental disorders | | | | |
ChiCTR-DDD-16009898: Research and and Popularization of Drug Metabolizing Enzyme Gene and Transporter Gene Detection in Psychiatric Accurate Drug Administration |
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| Unknown status | N/A | | | | Shanghai Mental Health Center; Shanghai Mental Health Center, three-year project of shenkang | Psychiatric Disease | | | | |
NCT06217237: Optimization and Harmonization of Advanced MRI Sequences |
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| Completed | N/A | 400 | Europe | AD FDT DBL GROUP | IRCCS Centro Neurolesi "Bonino-Pulejo" | Dementia Frontal, Dementia Alzheimers, Lewy Body Variant of Alzheimer Disease, Neuro-Degenerative Disease | 12/20 | 01/21 | | |
ChiCTR1900022440: The effects of premedication on postoperative behavioral disturbances in pediatric patients undergoing sevoflurane general anesthesia |
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| Recruiting | N/A | 120 | | premedication with oral melatonin ;premedication with oral midazolam ;premedication with equal volume of water | Department of Anesthesiology, Shengjing Hospital, China Medical University; Shengjing Hospital, National Nature Science Foundation of China (No. 81671311, No.81870838), the Key Research and Development Program of Liaoning Province (No.2018225004), the Outstanding Scientific Fund of Shengjing Hos | Postoperative behavioral disturbances | | | | |
ChiCTR-DOC-16010081: A diagnostic panel for common psychiatric disorders: a cohort study based on serum protein levels |
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| Unknown status | N/A | | | | Department of Psychosomatics and Psychiatry, Zhongda Hospital, School of Medicine, Southeast University; Zhongda Hospital, School of Medicine, Southeast University, National Natural Science Foundation of China (No. 81071101, 81571330 Yonggui Yuan, 81301167 Zhi Xu), Fundamental Research Funds for the Central Universities (Southeast University, No. 2242016K41053) | mental disorders (include schizophrenia, major depressive disorder, bipolar mania, bipolar depression and panic disorder ) | | | | |
ChiCTR1800014780: Mental Symptoms Evaluation Based on Recognition of Facial Expression and Speech |
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| Not yet recruiting | N/A | | | | the Mental Health Center of West China Hospital, Sichuan University; the Mental Health Center of West China Hospital, Sichuan University, balance provision from other researches | mental diseases (mainly featured with depresion, anxiety, delusion, hallucination) | | | | |
ChiCTR-RRC-16008714: Early screening, gene warning and health management of thyroid function and metabolic index for second pregnancy with advanced maternal age |
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| Recruiting | N/A | 1000 | | none | Department of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University; Zhongda Hospital, School of Medicine, Southeast University, National Natural Science Foundation of China (81570739 Ling Li) | Genetic disease；Gestational thyroid disease；Gestational diabetes mellitus；Gestational overweight and obesity ；Gestational hypertensive disease ；Gestational and perinatal mental disease | | | | |
ChiCTR1900022929: Multi-center random open-labeled parallel controlled trial for evaluating the effectiveness and safety of virtual-reality cognitive function rehabilitation software on cognitive functions for patients with mental disorder |
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| Not yet recruiting | N/A | 76 | | Rehabilitation with VR software ;none | First Affiliated Hospital, Zhejiang University School of Medicine; Hangzhou Yikang Medical Technology Limited Company, Hangzhou Yikang Medical Technology Limited Company | 精神障碍 | | | | |
ChiCTR-IOR-17012306: The effect of dexmedetomidine on prevention electroconvulsive therapy (ECT) postictal delirium |
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| Not yet recruiting | N/A | 450 | | 0.5ug/Kg dexmedetomidine ;Saline | Third Affiliated Hospital of Sun Yat-sen University; Third Affiliated Hospital of Sun Yat-sen University, Sun Yat-Sen University Clinical Research 5010 Program | Mental disease | | | | |
| Active, not recruiting | N/A | 400 | Europe | Psychotherapy | Lovisenberg Diakonale Hospital | Mental Disorders | 12/19 | 12/22 | | |
ChiCTR-OOB-15006347: Imaging investigation of the brain-gut interaction underlying functional constipation causing mental disorders |
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| Recruiting | N/A | 90 | | Drug treatment ;Drug treatment ;N/A | The First Affiliated Hospital of the Fourth Military Medical University of PLA; The First Affiliated Hospital of the Fourth Military Medical University of PLA, National Nature Science Foundation of China | Functonal constiptation | | | | |
NCT05808114: Quality of Life in Children With Psychiatric Disorders and Parental Well-being: Effects of Group CBT |
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| Completed | N/A | 109 | NA | Friends program, TAU | Helsinki University Central Hospital | Quality of Life | 12/19 | 12/19 | | |
CHW, NCT04028609: Community Health Worker Intervention to Improve Post-Hospital Outcomes |
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| Terminated | N/A | 55 | US | Healthy at Home, Services as Usual | University of Illinois at Chicago, National Institute on Disability, Independent Living, and Rehabilitation Research, Substance Abuse and Mental Health Services Administration (SAMHSA) | Chronic Disease (Physical), Mental Disorder | 03/20 | 03/20 | | |
ChiCTR1900027575: Study on the characteristics and relevant factors of shared mental models between doctors and patients in mental disorders |
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| Recruiting | N/A | 450 | | NA ;NA | The Fourth People's Hospital of Chengdu; The Fourth People's Hospital of Chengdu, self-finance | mental disorders | | | | |
NCT04149795: Physical Activity Recommendation Behaviour in German Psychologists |
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| Completed | N/A | 454 | Europe | Online questionnaire | Charite University, Berlin, Germany | Mental Disorder, Physical Activity | 04/20 | 04/20 | | |
ChiCTR1900027283: Screening of sleep disorders in patients with mental disorders in Beijing |
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| Recruiting | N/A | 2100 | | nil | Peking University Sixth Hospital; Peking University Sixth Hospital, nil | schizophrenia, depression and bipolar disorder | | | | |
NCT03377569: Subcortical Oscillations in Human Sleep Dysregulation |
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| Active, not recruiting | N/A | 15 | US | Sleep, PD and DBS | University of Colorado, Denver | Parkinson Disease, REM Behavior Disorder | 08/20 | 12/24 | | |
ChiCTR1900024230: Efficacy of Mindfulness Born Peace and Happiness (MBPH) - a new Mindfulness-based Intervention based on the teachings of Thich Nhat Hanh: A randomized controlled trial on common mental disorders |
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| Not yet recruiting | N/A | 66 | | MBPH ;Treatment as usual | The Chinese University of Hong Kong; Level of the institution：, The Chinese University of Hong Kong | common mental disorders | | | | |
ACTRN12623000047695: Does participation in Nae Umeed (New Hope) group psychosocial intervention improve mental health for carers of people with disability during the acute COVID-19 pandemic in India? A pre-post uncontrolled study. |
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| Completed | N/A | 100 | | | Kaaren Mathias, Herbertpur Christian Hosptial | mental distress, social exclusion | | | | |
ACTRN12622000858796: Process evaluation of a youth resilience intervention in urban North India during the COVID-19 pandemic – a mixed methods study |
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| Completed | N/A | 400 | | | Kaaren Mathias, Herbertpur Christian Hospital | youth mental distress, social exclusion, gender discrimination, poor mental health, Low resilience | | | | |
REPERADO, NCT04467229: Early Detection of Mental Disorders in Adolescents With Chronic Pain: Creation of a Screening Tool for Use by the General Practitioner |
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| Not yet recruiting | N/A | 30 | Europe | Focus group | Assistance Publique - Hôpitaux de Paris | Chronic Pain, Mental Disorder | 09/20 | 09/20 | | |
ChiCTR2000036032: Medical records based retrospective study on the decline rate of renal function and its influencing factors in inpatients with mental disorders |
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| Recruiting | N/A | 300 | | Nil | Third People's Hospital of Huzhou, Zhejiang; Huzhou Third People's Hospital, raise independently | Patients with mental disorders, Renal Function | | | | |
| Recruiting | N/A | 500 | RoW | | The Alfred, Janssen-Cilag Ltd., AstraZeneca, Hospira, now a wholly owned subsidiary of Pfizer | Pregnancy, Mental Disorders | 12/25 | 12/25 | | |