Sexually Transmitted Diseases  >>  tenofovir disoproxil fumarate  >>  Phase 2
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8 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
tenofovir disoproxil fumarate / Generic mfg.
NCT01489046 / 2011-003329-89: Safety, Efficacy and Dose-response Study of BMS-986001 in Subjects With HIV-1 Infection Who Are Treatment-naive

Terminated
2b
297
US, Canada, Europe, RoW
BMS-986001, Placebo matching with BMS-986001, Efavirenz, Sustiva®, Lamivudine, Epivir®, Tenofovir, Viread®
Bristol-Myers Squibb
HIV-1 Infection
03/13
07/14
NCT01737359: A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects.

Terminated
2a
2
RoW
amdoxovir 300 mg bid, DAPD, AMDX, amdoxovir 500 mg bid, tenofovir DF 300 mg qd, Viread
RFS Pharma, LLC
Human Immunodeficiency Virus Infection
02/13
03/13
NCT00046033: Comparing Standard-Dose Versus Adjusted-Dose Lopinavir/Ritonavir Therapy in HIV-Infected Persons With Drug Resistance

Completed
2
118
US
Lopinavir/ritonavir, Ritonavir, Saquinavir, Tenofovir disoproxil fumarate, Amprenavir
National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
03/03
 
NCT00088309: Effect of Tenofovir DF on Bone Metabolism in Children

Completed
2
50
US
Eye exam, Oral exam, CT scan, Neuropsychological testing, Electrocardiogram, Echocardiogram
National Cancer Institute (NCI)
HIV Infections
 
05/06
NCT00350272: Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

Completed
2
76
US
Elvucitabine, ACH-126,443, Lamivudine, 3TC, Tenofovir, Viread, Efavirenz, Sustiva
Alexion, Achillion, a wholly owned subsidiary of Alexion
HIV Infections
08/07
04/09
NCT00119379: Effectiveness of Nucleoside Supplementation or Switch to Tenofovir in Reversing Fat Loss in HIV Infected Adults

Completed
2
50
US
NucleomaxX, uridine, Tenofovir Disoproxil Fumarate, TDF
National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Lipodystrophy, Metabolic Diseases, Nutrition Disorders
10/08
10/08
NCT00131677: Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative Men

Completed
2
400
US
tenofovir disoproxil fumarate, Viread, placebo
Centers for Disease Control and Prevention, San Francisco Department of Public Health, AIDS Research Consortium of Atlanta
HIV Infection
08/09
08/09
NCT00896051 / 2009-010887-41: TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients

Completed
2
50
US, Europe, RoW
Atazanavir (ATV) 300 mg, Atazanavir (ATV) 400 mg, Ritonavir (rtv) 100 mg, Nucleo(side)/(tide) reverse transcriptase inhibitors (NRTIs), Etravirine (ETR) 200 mg, Tenofovir disoproxil fumarate (TDF) 300 mg
Janssen R&D Ireland
HIV Infections, Acquired Immunodeficiency Syndrome
04/12
04/12

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